nitroglycerin has been researched along with Hyperhomocysteinemia in 3 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to analyze the sensitivity of rats with prenatal hyperhomocysteinemia (hHCY) in respect of the development of behavioral correlates of headache and spreading cortical depolarization (CSD) in a migraine model induced by the administration of the nitric oxide (NO) donor nitroglycerin." | 8.12 | Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats. ( Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O, 2022) |
| " The aim of this study was to analyze the sensitivity of rats with prenatal hyperhomocysteinemia (hHCY) in respect of the development of behavioral correlates of headache and spreading cortical depolarization (CSD) in a migraine model induced by the administration of the nitric oxide (NO) donor nitroglycerin." | 4.12 | Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats. ( Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O, 2022) |
| " Dosing schedules that include a nitrate-free period often fail to ameliorate the development of nitrate tolerance, and, in fact, can result in an increase in rebound ischemia." | 2.42 | Organic nitrate tolerance and endothelial dysfunction: role of folate therapy. ( Leopold, JA; Loscalzo, J, 2003) |
| " Mechanisms responsible for endothelial dysfunction in hyperhomocyst(e)inaemia are poorly understood, but may involve impaired bioavailability of endothelium-derived nitric oxide (NO)." | 1.31 | Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans. ( Bode-Böger, SM; Böger, RH; Haynes, WG; Knapp, HR; Lentz, SR, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gerasimova, E | 1 |
| Yakovleva, O | 1 |
| Enikeev, D | 1 |
| Bogatova, K | 1 |
| Hermann, A | 1 |
| Giniatullin, R | 1 |
| Sitdikova, G | 1 |
| Leopold, JA | 1 |
| Loscalzo, J | 1 |
| Böger, RH | 1 |
| Lentz, SR | 1 |
| Bode-Böger, SM | 1 |
| Knapp, HR | 1 |
| Haynes, WG | 1 |
1 review available for nitroglycerin and Hyperhomocysteinemia
| Article | Year |
|---|---|
Organic nitrate tolerance and endothelial dysfunction: role of folate therapy.
Topics: Animals; Antioxidants; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Mice; Models | 2003 |
2 other studies available for nitroglycerin and Hyperhomocysteinemia
| Article | Year |
|---|---|
Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats.
Topics: Animals; Anxiety; Cortical Excitability; Female; Homocysteine; Hyperalgesia; Hyperhomocysteinemia; M | 2022 |
Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans.
Topics: Acute Disease; Adult; Arginine; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endotheliu | 2001 |