nitroglycerin has been researched along with Hot Flashes in 4 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Hot Flashes: A sudden, temporary sensation of heat predominantly experienced by some women during MENOPAUSE. (Random House Unabridged Dictionary, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether uninterrupted administration of transdermal nitroglycerin (NTG) to induce nitrate cross-tolerance decreased the frequency or severity of menopause-related hot flashes." | 9.69 | Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial. ( Cummings, SR; Ganz, P; Gibson, CJ; Grady, D; Huang, AJ; Raghunathan, H; Schembri, M; Vittinghoff, E, 2023) |
| "To describe the efficacy and tolerability of continuous nitroglycerin for treatment of hot flashes." | 9.22 | Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. ( Cummings, SR; Ganz, P; Grady, D; Huang, AJ; Schembri, M; Vittinghoff, E, 2016) |
| "To determine whether uninterrupted administration of transdermal nitroglycerin (NTG) to induce nitrate cross-tolerance decreased the frequency or severity of menopause-related hot flashes." | 5.69 | Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial. ( Cummings, SR; Ganz, P; Gibson, CJ; Grady, D; Huang, AJ; Raghunathan, H; Schembri, M; Vittinghoff, E, 2023) |
| "To describe the efficacy and tolerability of continuous nitroglycerin for treatment of hot flashes." | 5.22 | Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. ( Cummings, SR; Ganz, P; Grady, D; Huang, AJ; Schembri, M; Vittinghoff, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, AJ | 2 |
| Cummings, SR | 2 |
| Ganz, P | 2 |
| Schembri, M | 2 |
| Raghunathan, H | 1 |
| Vittinghoff, E | 2 |
| Gibson, CJ | 1 |
| Grady, D | 2 |
| Tuomikoski, P | 2 |
| Ebert, P | 2 |
| Groop, PH | 2 |
| Haapalahti, P | 2 |
| Hautamäki, H | 2 |
| Rönnback, M | 2 |
| Ylikorkala, O | 2 |
| Mikkola, TS | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Vascular Findings Between Symptomatic and Asymptomatic Postmenopausal Women Before and During Hormone Therapy: A Randomized, Placebo-controlled Prospective Study[NCT00668603] | 160 participants (Actual) | Interventional | 2005-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for nitroglycerin and Hot Flashes
| Article | Year |
|---|---|
Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial.
Topics: Double-Blind Method; Female; Hot Flashes; Humans; Menopause; Nitrates; Nitroglycerin; Perimenopause; | 2023 |
Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial.
Topics: Administration, Cutaneous; Adult; Dose-Response Relationship, Drug; Female; Hot Flashes; Humans; Men | 2016 |
Effect of hot flushes on vascular function: a randomized controlled trial.
Topics: Administration, Cutaneous; Administration, Oral; Albuterol; Endothelium, Vascular; Estradiol; Estrog | 2009 |
1 other study available for nitroglycerin and Hot Flashes
| Article | Year |
|---|---|
Evidence for a role of hot flushes in vascular function in recently postmenopausal women.
Topics: Albuterol; Endothelium, Vascular; Female; Hot Flashes; Humans; Middle Aged; Nitroglycerin; Postmenop | 2009 |