nitroglycerin has been researched along with Hibernation, Myocardial in 20 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitroglycerin only has a limited late preconditioning protective effect in conscious animals submitted to a reversible prolonged ischemia since it protects against arrhythmias but not against stunning." | 7.74 | Nitroglycerin induces late preconditioning against arrhythmias but not stunning in conscious sheep. ( Lascano, EC; Negroni, JA; Valle, HF, 2007) |
| "Nitroglycerin only has a limited late preconditioning protective effect in conscious animals submitted to a reversible prolonged ischemia since it protects against arrhythmias but not against stunning." | 3.74 | Nitroglycerin induces late preconditioning against arrhythmias but not stunning in conscious sheep. ( Lascano, EC; Negroni, JA; Valle, HF, 2007) |
| " Also, CBFV responses to acetylcholine, nitroglycerin, and reactive hyperemia (20-s CAO) were not significantly different on days 1 and 2." | 3.71 | Myocardial stunning in exercise-induced ischemia in dogs: lack of late preconditioning. ( Berdeaux, A; De Curzon, OP; Ghaleh, B; Giudicelli, JF; Hittinger, L; Tissier, R, 2001) |
| "Deferoxamine treated control myocytes responded similarly." | 1.36 | Hypoxia inducible factor-1 protects against nitrate tolerance and stunning in rabbit cardiac myocytes. ( Tan, T; Weiss, HR, 2010) |
| "A pig model of myocardial hibernation of 24 hours to 7 days was created through severe left anterior descending coronary artery stenosis with coronary flow reductions of approximately 40%, producing severe regional left ventricular dysfunction but no infarction in seven pigs." | 1.30 | Nitroglycerin enhances the ability of dobutamine stress echocardiography to detect hibernating myocardium. ( Chen, C; Chen, L; Gillam, L; Ma, L; Waters, DD, 1997) |
| "Pretreatment with chelerythrine alone (group IV, n = 5) did not alter stunning." | 1.30 | Nitroglycerin induces late preconditioning against myocardial stunning via a PKC-dependent pathway. ( Banerjee, S; Bolli, R; Dawn, B; Manchikalapudi, S; Qiu, Y; Shirk, G; Takano, H; Tang, XL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (65.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, T | 1 |
| Weiss, HR | 1 |
| Lishmanov, IuB | 1 |
| Minin, SM | 1 |
| Efimova, IIu | 1 |
| Babokin, VE | 1 |
| Saushkina, IuV | 1 |
| Lascano, EC | 1 |
| Valle, HF | 1 |
| Negroni, JA | 1 |
| Przyklenk, K | 1 |
| Kloner, RA | 1 |
| Ling, LH | 1 |
| Tei, C | 1 |
| Pellikka, PA | 1 |
| Iwamoto, T | 1 |
| Miura, T | 1 |
| Urabe, K | 1 |
| Itoya, M | 1 |
| Shimamoto, K | 1 |
| Iimura, O | 1 |
| Pontillo, D | 1 |
| Yamaoka, O | 1 |
| Kinoshita, M | 1 |
| Pomar Domingo, F | 1 |
| Cosín Aguilar, J | 1 |
| Hernándiz, A | 1 |
| Portoles, M | 1 |
| Pallarés, V | 1 |
| Andrés, F | 1 |
| Morishima, N | 1 |
| Mentzer, RM | 1 |
| Rahko, PS | 1 |
| Molina-Viamonte, V | 1 |
| Canver, CC | 1 |
| Chopra, PS | 1 |
| Love, RB | 1 |
| Cook, TD | 1 |
| Hegge, JO | 1 |
| Lasley, RD | 1 |
| Ma, L | 1 |
| Chen, L | 1 |
| Gillam, L | 1 |
| Waters, DD | 1 |
| Chen, C | 1 |
| Sias, TM | 1 |
| Watson, DD | 1 |
| Beller, GA | 1 |
| Oudiz, RJ | 1 |
| Smith, DE | 1 |
| Pollak, AJ | 1 |
| Mena, I | 1 |
| Shapiro, SM | 1 |
| Ginzton, LE | 1 |
| Narahara, KA | 1 |
| Banerjee, S | 1 |
| Tang, XL | 2 |
| Qiu, Y | 1 |
| Takano, H | 2 |
| Manchikalapudi, S | 1 |
| Dawn, B | 2 |
| Shirk, G | 1 |
| Bolli, R | 3 |
| Shinmura, K | 1 |
| Hill, M | 1 |
| Kalweit, G | 1 |
| Schipke, J | 1 |
| Elsner, J | 1 |
| Boeken, U | 1 |
| Feindt, P | 1 |
| Gams, E | 1 |
| De Curzon, OP | 1 |
| Ghaleh, B | 1 |
| Tissier, R | 1 |
| Giudicelli, JF | 1 |
| Hittinger, L | 1 |
| Berdeaux, A | 1 |
| Saeed, MA | 1 |
| Saeed, S | 1 |
| Hyder, SW | 1 |
| Khan, AN | 1 |
| Leesar, MA | 1 |
| Stoddard, MF | 1 |
| Jasti, VG | 1 |
| Masden, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Measurement of Matrix Metalloproteinase Activation Post Myocardial Infarction[NCT00576121] | 0 participants (Actual) | Observational | 2008-07-31 | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitroglycerin and Hibernation, Myocardial
| Article | Year |
|---|---|
Assessment of myocardial viability in chronic left ventricular dysfunction.
Topics: Chronic Disease; Deoxyglucose; Dobutamine; Echocardiography; Fluorine Radioisotopes; Fluorodeoxygluc | 1995 |
Is nitroglycerin useful for the enhancement of viability detection with myocardial perfusion imaging?
Topics: Coronary Disease; Humans; Image Enhancement; Myocardial Stunning; Nitroglycerin; Tomography, Emissio | 1999 |
4 trials available for nitroglycerin and Hibernation, Myocardial
| Article | Year |
|---|---|
Safety, tolerance, and efficacy of adenosine as an additive to blood cardioplegia in humans during coronary artery bypass surgery.
Topics: Adenosine; Adolescent; Cardioplegic Solutions; Cardiovascular Agents; Coronary Artery Bypass; Dopami | 1997 |
Coronary vascular stunning in bypass operations during reperfusion and treatment with nitroglycerin.
Topics: Aged; Coronary Artery Bypass; Coronary Vessels; Female; Humans; Hypertension; Male; Myocardial Reper | 2000 |
Enhanced 99Tc(m)-MIBI SPECT detection of hibernating myocardium following the use of sub-lingual nitroglycerine.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Coronary Circulation; Coronary Disease; Fem | 2001 |
Delayed preconditioning-mimetic action of nitroglycerin in patients undergoing coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Blood Flow Velocity; Blood Pressure; Chest Pain; Collateral Circulat | 2001 |
14 other studies available for nitroglycerin and Hibernation, Myocardial
| Article | Year |
|---|---|
Hypoxia inducible factor-1 protects against nitrate tolerance and stunning in rabbit cardiac myocytes.
Topics: Animals; Calcium-Binding Proteins; Carbazoles; Cell Shape; Cyclic GMP-Dependent Protein Kinases; Def | 2010 |
[Comparative characteristics of revealing hibernated myocardium by means of perfusion and metabolic scintigraphy].
Topics: Coronary Artery Disease; Fatty Acids; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imagin | 2012 |
Nitroglycerin induces late preconditioning against arrhythmias but not stunning in conscious sheep.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Consciousness; Coronary Circulation; Disease | 2007 |
Low-dose i.v. acetylcholine acts as a "preconditioning-mimetic" in the canine model.
Topics: Acetylcholine; Animals; Disease Models, Animal; Dogs; Heart; Humans; Infusions, Intravenous; Myocard | 1995 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating | 1993 |
[The vital myocardium and the echo-nitrate test].
Topics: Echocardiography; Humans; Myocardial Stunning; Nitroglycerin | 1993 |
Role of collateral flow in a pharmacological stress test (a combination of low-dose dobutamine and a vasodilator) as a predictor of wall motion reversibility.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Cardiotonic Agents; Collateral Circulation; | 1995 |
[Effects of nitroglycerin and nifedipine on stunned myocardium due to brief repeated ischemias].
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Data Interpretation, Statistical; Dogs; Ele | 1996 |
The effects of modulation of the L-arginine-nitric oxide pathway on myocardial stunning following repetitive coronary occlusion in dogs.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Disease; Dogs; Enzyme Inhibitors; F | 1995 |
Nitroglycerin enhances the ability of dobutamine stress echocardiography to detect hibernating myocardium.
Topics: Animals; Confounding Factors, Epidemiologic; Diagnosis, Differential; Dobutamine; Drug Synergism; Ec | 1997 |
Nitrate-enhanced thallium 201 single-photon emission computed tomography imaging in hibernating myocardium.
Topics: Female; Humans; Image Enhancement; Male; Middle Aged; Myocardial Stunning; Nitroglycerin; Sensitivit | 1999 |
Nitroglycerin induces late preconditioning against myocardial stunning via a PKC-dependent pathway.
Topics: Alkaloids; Animals; Benzophenanthridines; Cardiotonic Agents; Enzyme Inhibitors; Ischemic Preconditi | 1999 |
Nitric oxide donors attenuate myocardial stunning in conscious rabbits.
Topics: Analysis of Variance; Animals; Blood Pressure; Consciousness; Heart; Heart Rate; Hemodynamics; Infus | 1999 |
Myocardial stunning in exercise-induced ischemia in dogs: lack of late preconditioning.
Topics: Acetylcholine; Animals; Coronary Circulation; Coronary Disease; Dogs; Endothelium, Vascular; Hemodyn | 2001 |