Page last updated: 2024-11-01

nitroglycerin and Hemorrhage

nitroglycerin has been researched along with Hemorrhage in 27 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Hemorrhage: Bleeding or escape of blood from a vessel.

Research Excerpts

ExcerptRelevanceReference
"The threshold for ventricular fibrillation induced by a 200 msec train of pulses was measured during a control period and during an intravenous infusion of nitroglycerin in 14 nonischemic open chest dogs."7.65Effect of nitroglycerin on ventricular fibrillation threshold of nonischemic myocardium. ( Dashkoff, N; Pitt, B; Roland, JM; Varghese, PJ, 1976)
" Nitroglycerin applied in a low dosage with exclusive venodilator effect was added for treatment of pulmonary edema and left ventricular failure."5.26[Hemorrhagic pulmonary edema and cardiac failure following isolated head injury. Treatment with dobutamine and nitroglycerin (author's transl)]. ( Jüngst, BK; Schranz, D; Stopfkuchen, H, 1981)
"The aim of the study was to investigate the use of prophylactic nitroglycerin patch in patients who applied to our clinic with occlusion icter and underwent endoscopic retrograde cholangiopancreatography (ERCP) for complications such as pancreatitis, bleeding, perforation that may occur during and after the procedure, duration of the procedure, length of hospitalization, precut and selective cannulation rates, and mortality."4.31The effect of using nitroderm TTS in ERCP on precut, selective cannulation, and bleeding. ( Calta, AF; Duran, A, 2023)
"The threshold for ventricular fibrillation induced by a 200 msec train of pulses was measured during a control period and during an intravenous infusion of nitroglycerin in 14 nonischemic open chest dogs."3.65Effect of nitroglycerin on ventricular fibrillation threshold of nonischemic myocardium. ( Dashkoff, N; Pitt, B; Roland, JM; Varghese, PJ, 1976)
" Pressure was altered by intravenous bolus injections and continuous infusions of nitroglycerin and methoxamine and also by hemorrhage."3.65The role of arterial baroreceptors in the regulation of arterial pressure in conscious dogs. ( Braunwald, E; Heyndrickx, GR; McRitchie, RJ; Vatner, SF, 1976)
"Nitroglycerin was ineffective in two patients and two other patients required greater than 20 micrograms/kg/min."2.66Comparison of intravenous nitroprusside, nitroprusside-captopril, and nitroglycerin for deliberate hypotension during posterior spine fusion in adults. ( Asher, M; Fox, DK; Porter, SS, 1988)
"Nitroglycerin was utilized in combination with general anesthesia in order to reduce mean arterial blood pressure with the objective of reducing operative blood loss in 26 consecutive patients undergoing radical hysterectomy and pelvic lymphadenectomy."1.27A deliberate hypotensive technique for decreasing blood loss during radical hysterectomy and pelvic lymphadenectomy. ( Burrell, MO; Chambers, DA; Franklin, EW; Mogelnicki, SR; Powell, JL, 1983)
" Nitroglycerin applied in a low dosage with exclusive venodilator effect was added for treatment of pulmonary edema and left ventricular failure."1.26[Hemorrhagic pulmonary edema and cardiac failure following isolated head injury. Treatment with dobutamine and nitroglycerin (author's transl)]. ( Jüngst, BK; Schranz, D; Stopfkuchen, H, 1981)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's5 (18.52)18.2507
2000's3 (11.11)29.6817
2010's1 (3.70)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Calta, AF1
Duran, A1
Kanbak, M1
Oc, B1
Salman, MA1
Ocal, T1
Oc, M1
Ba, ZF2
Kuebler, JF1
Rue, LW1
Bland, KI1
Wang, P2
Chaudry, IH2
Tjandra, JJ1
Tan, JJ1
Lim, JF1
Murray-Green, C1
Kennedy, ML1
Lubowski, DZ1
Previsdomini, M1
Stocker, R1
Corti, R1
Cerutti, B1
Perren, A1
Schranz, D1
Stopfkuchen, H1
Jüngst, BK1
Bertrand, D1
Laxenaire, MC1
Wayoff, M1
Fater, DC1
Sundet, WD2
Schultz, HD1
Goetz, KL2
Powell, JL1
Mogelnicki, SR1
Franklin, EW1
Chambers, DA1
Burrell, MO1
Perotti, GS1
Bosch, J1
Bruix, J1
Mas, A1
Navasa, M1
Rodés, J1
Harkins, JD1
Tobin, T1
Rusyn, VI1
Peresta, IuIu1
Rammal', F1
Chavarha, M1
Hackett, RP1
Ducharme, NG1
Gleed, RD1
Erb, HN1
Mitchell, LM1
Soderholm, LV1
Millard, RW1
Hodgkin, BC1
Nelson, CV1
Dashkoff, N1
Roland, JM1
Varghese, PJ1
Pitt, B1
McRitchie, RJ1
Vatner, SF1
Heyndrickx, GR1
Braunwald, E1
Porter, SS1
Asher, M1
Fox, DK1
Hakumäki, MO1
Wang, BC1
Wang, YC1
Wang, JM1
Fung, TJ1
Chen, HI1
Abiko, Y1
Minamidate, A1
Hashikawa, T1
Bing, RJ3
Hellberg, K3
Wayland, H3
Rickart, A2
Smith, ER1
Redwood, DR1
McCarron, WE1
Epstein, SE1
Lebedev, AA1
Malachevskaia, AS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised, Double-blind, Placebo-controlled, Parallel-group, Multicentre, Interventional Clinical Trial to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus in the Symptomatic Treatment of Haemorrhoids[NCT05750563]80 participants (Anticipated)Interventional2023-02-28Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for nitroglycerin and Hemorrhage

ArticleYear
Rolling review: the treatment of major complications of cirrhosis.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carcinoma, Hepatocellular; Catheterization; Diuretics; Hemorrh

1994
Racing horses, nitroglycerin and exercise induced pulmonary haemorrhage (EIPH).
    Equine veterinary journal, 1995, Volume: 27, Issue:4

    Topics: Animals; Blood Pressure; Capillaries; Hemorrhage; Horse Diseases; Horses; Lung; Lung Diseases; Muscl

1995

Trials

3 trials available for nitroglycerin and Hemorrhage

ArticleYear
Peroperative effects of fresh frozen plasma and antithrombin III on heparin sensitivity and coagulation during nitroglycerine infusion in coronary artery bypass surgery.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:7

    Topics: Aged; Anticoagulants; Antithrombin III; Blood Coagulation; Coronary Artery Bypass; Coronary Artery D

2011
Rectogesic (glyceryl trinitrate 0.2%) ointment relieves symptoms of haemorrhoids associated with high resting anal canal pressures.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2007, Volume: 9, Issue:5

    Topics: Adult; Aged; Anal Canal; Female; Hemorrhage; Hemorrhoids; Humans; Male; Manometry; Middle Aged; Nitr

2007
Comparison of intravenous nitroprusside, nitroprusside-captopril, and nitroglycerin for deliberate hypotension during posterior spine fusion in adults.
    Journal of clinical anesthesia, 1988, Volume: 1, Issue:2

    Topics: Administration, Oral; Adult; Blood Pressure; Captopril; Female; Ferricyanides; Hemorrhage; Humans; H

1988

Other Studies

22 other studies available for nitroglycerin and Hemorrhage

ArticleYear
The effect of using nitroderm TTS in ERCP on precut, selective cannulation, and bleeding.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2023, Volume: 29, Issue:3

    Topics: Catheterization; Cholangiopancreatography, Endoscopic Retrograde; Hemorrhage; Humans; Nitroglycerin;

2023
Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: role of vascular endothelial cell function.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6

    Topics: Acetylcholine; Animals; Aorta; Body Weight; Cardiac Output; Cardiopulmonary Resuscitation; Endotheli

2003
Time course of hemoglobin concentrations in the intensive care unit in nonbleeding patients with acute coronary syndrome.
    The American journal of cardiology, 2007, Aug-15, Volume: 100, Issue:4

    Topics: Acute Disease; Aged; Coronary Care Units; Coronary Disease; Drug Therapy, Combination; Electrocardio

2007
[Hemorrhagic pulmonary edema and cardiac failure following isolated head injury. Treatment with dobutamine and nitroglycerin (author's transl)].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:4

    Topics: Brain Injuries; Cardiac Output, Low; Child; Dobutamine; Hematoma, Subdural; Hemorrhage; Humans; Male

1981
[The role of nitroglycerin in controlled hypotension in surgery of the middle ear].
    Journal francais d'oto-rhino-laryngologie; audiophonologie, chirurgie maxillo-faciale, 1982, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Blood Pressure; Ear, Middle; Female; Heart Rate; Hemorrhage; Humans; Hypotension,

1982
Arterial baroreceptors have minimal physiological effects on adrenal medullary secretion.
    The American journal of physiology, 1983, Volume: 244, Issue:2

    Topics: Adrenal Medulla; Animals; Arteries; Blood Pressure; Carotid Arteries; Denervation; Dogs; Epinephrine

1983
A deliberate hypotensive technique for decreasing blood loss during radical hysterectomy and pelvic lymphadenectomy.
    American journal of obstetrics and gynecology, 1983, Sep-15, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Transfusion; Female; Hemorrhage; Humans; Hypotension, Controlled; Hys

1983
A new technique: nitroglycerin to induce hypotension for Harrington rod procedure.
    AANA journal, 1981, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Blood Volume; Child; Female; Hemorrhage; Humans; Hypotension, Controlled; Male; M

1981
Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation.
    The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Hematocrit; Hemorrhage; Hypoxia; Isot

1993
[The use of nitroglycerin in integral treatment of hemorrhage with portal hypertension].
    Klinichna khirurhiia, 1997, Issue:11-12

    Topics: Acute Disease; Adult; Esophagus; Female; Hemorrhage; Humans; Hypertension, Portal; Male; Middle Aged

1997
Oral nitroglycerin paste did not lower pulmonary capillary pressure during treadmill exercise.
    Equine veterinary journal. Supplement, 1999, Issue:30

    Topics: Administration, Oral; Animals; Exercise Test; Female; Hemorrhage; Horse Diseases; Horses; Male; Nitr

1999
Effect of ventricular end-diastolic volume on vectorcardiographic potentials of the pig.
    The American journal of physiology, 1978, Volume: 235, Issue:2

    Topics: Action Potentials; Animals; Blood Pressure; Coronary Disease; Heart; Heart Rate; Hemorrhage; Myocard

1978
Effect of nitroglycerin on ventricular fibrillation threshold of nonischemic myocardium.
    The American journal of cardiology, 1976, Volume: 38, Issue:2

    Topics: Action Potentials; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Co

1976
The role of arterial baroreceptors in the regulation of arterial pressure in conscious dogs.
    Circulation research, 1976, Volume: 39, Issue:5

    Topics: Animals; Aorta; Blood Pressure; Carotid Sinus; Denervation; Dogs; Dose-Response Relationship, Drug;

1976
Aortic baroreceptor discharge during nonhypotensive hemorrhage in anesthetized dogs.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 2

    Topics: Action Potentials; Animals; Aorta; Blood Pressure; Dogs; Hemodynamics; Hemorrhage; Nitroglycerin; Pr

1985
Effects of nitroglycerin and nitroprusside on the pulmonary hemorrhagic edema induced by cerebral compression and epinephrine.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1985, Volume: 9, Issue:2

    Topics: Animals; Blood Pressure; Brain Injuries; Epinephrine; Female; Ferricyanides; Hemorrhage; Male; Nitro

1985
Discordant response to nitroglycerin of strain gauge arch and maximum rate of rise of left ventricular pressure in dogs.
    Fukushima journal of medical science, 1972, Volume: 18, Issue:3

    Topics: Animals; Blood Transfusion; Dipyridamole; Dogs; Female; Heart; Heart Ventricles; Hemorrhage; Male; N

1972
Microcirculation of the heart.
    Advances in experimental medicine and biology, 1972, Volume: 22

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Cats; Coronary Circulation; Coronary Vess

1972
[Direct visualization of coronary microcirculation].
    Kardiologiia, 1972, Volume: 12, Issue:3

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Cats; Cineradiography; Coronary Circulati

1972
Coronary artery occlusion in the conscious dog. Effects of alterations in arterial pressure produced by nitroglycerin, hemorrhage, and alpha-adrenergic agonists on the degree of myocardial ischemia.
    Circulation, 1973, Volume: 47, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Heart Rate; Hemorrhage; Hyper

1973
[Homeostatic kidney functions in hemorrhage and vasomotor collapse].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1968, Volume: 54, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Amyl Nitrite; Animals; Denervation; Dogs; Hemodynamics; Hemorrhage; H

1968
Studies on the coronary microcirculation by direct visualization.
    Giornale italiano di cardiologia, 1971, Volume: 1, Issue:5

    Topics: Animals; Blood Flow Velocity; Capillaries; Cardiac Catheterization; Cats; Coronary Circulation; Eryt

1971