nitroglycerin has been researched along with Hematochezia in 39 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Hematochezia: The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Utilization data linked to the results of a double-blind, placebo-controlled trial demonstrating the efficacy of the terlipressin-glycerin trinitrate combination (TER-GTN) in the reduction of mortality at day 42 for haemorragic patients due to rupture of oesophageal varices." | 5.09 | Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients. ( Combier, E; de Pouvourville, G; Joseph, A; Letoumelin, P; Levacher, S; Pourriat, JL, 1999) |
| "Nitroglycerin dosage was not advanced appropriately in 78% of episodes despite evidence of bradycardia, hypertension and peripheral vasoconstriction." | 3.68 | Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding. ( Burns, SM; Luer, J; Martin, M; Merrill, P; Stone, DD, 1993) |
| "Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin." | 2.41 | The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000) |
| "Bleeding from esophageal varices presents a considerable challenge to clinicians." | 2.40 | Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination? ( Cello, JP, 1997) |
| "In conclusion, chronic administration of organic nitrates, allowing for a nitrate-free interval each day, to cirrhotic patients reduces portal pressure with a variable, dose-dependent effect on azygos blood flow." | 2.39 | Organic nitrates in portal hypertension. ( Hayes, PC; Jones, AL, 1994) |
| "The pharmacologic treatment of portal hypertension should be able to stop as well as to prevent variceal hemorrhage." | 2.38 | Pharmacologic treatment of portal hypertension. ( Groszmann, RJ; Rodríguez-Pérez, F, 1992) |
| "Bleeding from esophagogastric varices carries a high mortality rate." | 2.38 | Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence. ( Marshall, JB, 1991) |
| "Pretreatment with nitroglycerin, 10(-7), 3 x 10(-7), 10(-6) M for 5 min produced a significant improvement of intestinal tissue morphology and a decrease in the release of both lactate dehydrogenase and malondialdehyde." | 1.31 | Protective effects of nitroglycerin-induced preconditioning mediated by calcitonin gene-related peptide in rat small intestine. ( Dun, Y; Hao, YB; Wu, YX; Zhang, Y; Zhao, RR, 2001) |
| "Bleeding from oesophageal varices is an uncommon but potentially fatal condition that often leads to expensive hospitalizations in intensive care or high-dependency units." | 1.29 | Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK. ( Bosanquet, N; Burroughs, AK; Greenslade, L; Matheson, LA; Matsaganis, M; McCormick, PA, 1995) |
| "In 40 patients with esophageal varices, esophageal variceal pressure was assessed endoscopically using a pneumatic pressure sensor." | 1.29 | Clinical significance of esophageal variceal pressure in patients with esophageal varices. ( Bandoh, T; Kitano, S; Kobayashi, M; Mitarai, Y; Yoshida, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (23.08) | 18.7374 |
| 1990's | 27 (69.23) | 18.2507 |
| 2000's | 3 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kojima, K | 1 |
| Imazu, H | 1 |
| Matsumura, M | 1 |
| Honda, Y | 1 |
| Umemoto, N | 1 |
| Moriyasu, H | 1 |
| Orihashi, T | 1 |
| Uejima, M | 1 |
| Morioka, C | 1 |
| Komeda, Y | 1 |
| Uemura, M | 1 |
| Yoshiji, H | 1 |
| Fukui, H | 1 |
| Levacher, S | 2 |
| Letoumelin, P | 2 |
| Pateron, D | 1 |
| Blaise, M | 1 |
| Lapandry, C | 1 |
| Pourriat, JL | 2 |
| McCormick, PA | 1 |
| Greenslade, L | 1 |
| Matheson, LA | 1 |
| Matsaganis, M | 1 |
| Bosanquet, N | 1 |
| Burroughs, AK | 3 |
| Avgerinos, A | 1 |
| Armonis, A | 1 |
| Bandoh, T | 1 |
| Mitarai, Y | 1 |
| Kitano, S | 1 |
| Yoshida, T | 1 |
| Kobayashi, M | 1 |
| D'Amico, G | 1 |
| Traina, M | 1 |
| Vizzini, G | 1 |
| Tinè, F | 1 |
| Politi, F | 1 |
| Montalbano, L | 1 |
| Luca, A | 1 |
| Pasta, L | 1 |
| Pagliaro, L | 1 |
| Morabito, A | 1 |
| Dattani, BH | 1 |
| Troyer, SD | 1 |
| Truitt, CA | 1 |
| Jones, AL | 1 |
| Hayes, PC | 3 |
| Silvain, C | 2 |
| Carpentier, S | 1 |
| Sautereau, D | 2 |
| Czernichow, B | 1 |
| Métreau, JM | 1 |
| Fort, E | 2 |
| Ingrand, P | 2 |
| Boyer, J | 1 |
| Pillegand, B | 2 |
| Doffël, M | 1 |
| Burns, SM | 2 |
| Martin, M | 1 |
| Merrill, P | 1 |
| Luer, J | 1 |
| Stone, DD | 1 |
| Sanyal, AJ | 1 |
| Freedman, AM | 1 |
| Luketic, VA | 1 |
| Purdum, PP | 1 |
| Shiffman, ML | 1 |
| Tisnado, J | 1 |
| Cole, PE | 1 |
| Patch, D | 1 |
| Cello, JP | 1 |
| Renner, EL | 1 |
| Eramishantsev, AK | 1 |
| Shertsinger, AG | 2 |
| Kitsenko, EA | 2 |
| Bour, AV | 1 |
| Bokhian, TS | 1 |
| Musin, RA | 1 |
| Nader, A | 1 |
| Grace, ND | 1 |
| Combier, E | 1 |
| Joseph, A | 1 |
| de Pouvourville, G | 1 |
| Masaki, E | 1 |
| Takinami, M | 1 |
| Kurata, Y | 1 |
| Kagaya, S | 1 |
| Ahmed, A | 1 |
| Stein, M | 1 |
| Hirshberg, A | 1 |
| Bosch, J | 2 |
| Dun, Y | 1 |
| Hao, YB | 1 |
| Wu, YX | 1 |
| Zhang, Y | 1 |
| Zhao, RR | 1 |
| Bush, HL | 1 |
| Nabseth, DC | 1 |
| Matloff, DS | 1 |
| Rodríguez-Pérez, F | 1 |
| Groszmann, RJ | 2 |
| Jenkins, SA | 1 |
| Stein, LB | 1 |
| Dabezies, MA | 1 |
| Silverman, M | 1 |
| Brozena, SC | 1 |
| Marshall, JB | 1 |
| Söderlund, C | 1 |
| Eriksson, LS | 1 |
| Beauchant, M | 1 |
| Martin, MJ | 1 |
| Sirinek, KR | 1 |
| Adcock, DK | 1 |
| Levine, BA | 1 |
| Westaby, D | 2 |
| Gimson, AE | 1 |
| Polson, RJ | 1 |
| Williams, R | 2 |
| García-Pagán, JC | 1 |
| Terés, J | 1 |
| García-Tsao, G | 1 |
| Navasa, M | 1 |
| Mas, A | 1 |
| Rodés, J | 1 |
| Maier, KP | 1 |
| Gimson, A | 1 |
| Tuggle, DW | 1 |
| Bennett, KG | 1 |
| Scott, J | 1 |
| Tunell, WP | 1 |
| Kuzin, GA | 1 |
| Nikitina, EA | 1 |
| Smith, GH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903): A Multicenter, Single-blind, Randomised Controlled Trial[NCT04028323] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-07-16 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for nitroglycerin and Hematochezia
| Article | Year |
|---|---|
Balloon tamponade technique and efficacy in variceal haemorrhage.
Topics: Balloon Occlusion; Catheterization; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hum | 1994 |
Nitroglycerin use in variceal hemorrhage.
Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Midd | 1994 |
Organic nitrates in portal hypertension.
Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans | 1994 |
Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination?
Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Hemosta | 1997 |
[Esophageal varices].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Combined Modality Therapy; Drug Therapy, Combi | 1997 |
Pharmacologic intervention during the acute bleeding episode.
Topics: Acute Disease; Antihypertensive Agents; Blood Flow Velocity; Drug Therapy, Combination; Esophageal a | 1999 |
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination | 2000 |
Treatment of acute variceal bleeding.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Drug Administration Schedule; Emergencies; Endosc | 1992 |
Pharmacologic treatment of portal hypertension.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Gastrointestinal Hemorrha | 1992 |
Acute management of bleeding oesophageal varices.
Topics: Acute Disease; Animals; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Esophageal an | 1992 |
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D | 1992 |
Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence.
Topics: Balloon Occlusion; Catheterization; Clinical Protocols; Education, Medical, Continuing; Endoscopy, G | 1991 |
Medical and surgical treatment of acute bleeding from esophageal varices in patients with cirrhosis.
Topics: Catheterization; Clinical Trials as Topic; Endoscopy, Gastrointestinal; Esophageal and Gastric Varic | 1991 |
[Drug treatment of bleeding esophageal varices. Acute therapy and prevention of recurrence].
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Drug Therapy, Combination; Esophageal and Gastr | 1986 |
10 trials available for nitroglycerin and Hematochezia
| Article | Year |
|---|---|
Early administration of terlipressin plus glyceryl trinitrate to control active upper gastrointestinal bleeding in cirrhotic patients.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; G | 1995 |
Terlipressin or vasopressin plus transdermal nitroglycerin in a treatment strategy for digestive bleeding in cirrhosis. A randomized clinical trial. Liver Study Group of V. Cervello Hospital.
Topics: Administration, Cutaneous; Adult; Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; F | 1994 |
Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: a multicenter randomized trial.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Drug Therapy, Combination; Emergencies; Esop | 1993 |
Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy.
Topics: Adult; Aged; Balloon Occlusion; Catheterization; Combined Modality Therapy; Emergencies; Esophageal | 1996 |
Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients.
Topics: Acute Disease; Antihypertensive Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Co | 1999 |
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D | 1992 |
A randomized trial of terlipressin plus nitroglycerin vs. balloon tamponade in the control of acute variceal hemorrhage.
Topics: Adult; Aged; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Emergencies; Esophageal | 1990 |
Controlled clinical trial of injection sclerotherapy for active variceal bleeding.
Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Human | 1989 |
Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: a placebo-controlled clinical trial.
Topics: Administration, Cutaneous; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Dru | 1989 |
Haemodynamic response to intravenous vasopressin and nitroglycerin in portal hypertension.
Topics: Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, | 1988 |
16 other studies available for nitroglycerin and Hematochezia
| Article | Year |
|---|---|
Sclerotherapy for gastric fundal variceal bleeding: is complete obliteration possible without cyanoacrylate?
Topics: Adult; Aged; Cyanoacrylates; Esophageal and Gastric Varices; Feasibility Studies; Female; Gastric Fu | 2005 |
Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK.
Topics: Acute Disease; Costs and Cost Analysis; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; | 1995 |
Clinical significance of esophageal variceal pressure in patients with esophageal varices.
Topics: Aged; Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; E | 1994 |
Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding.
Topics: Bradycardia; Clinical Protocols; Constriction, Pathologic; Drug Monitoring; Drug Therapy, Combinatio | 1993 |
Therapeutic benefit of vaso-active drugs for acute variceal bleeding: a real pharmacological effect, or a side-effect of definitions in trials?
Topics: Double-Blind Method; Drug Combinations; Gastrointestinal Hemorrhage; Humans; Lypressin; Nitroglyceri | 1996 |
[The conservative therapy of acute esophagogastric hemorrhages in portal hypertension patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Endosc | 1998 |
Anesthetic management of high-risk cardiac patients undergoing noncardiac surgery under the support of intraaortic balloon pump.
Topics: Aged; Anesthesia, General; Angina Pectoris; Carcinoma; Colectomy; Colon, Sigmoid; Coronary Disease; | 1999 |
Medical consequences of terrorism. The conventional weapon threat.
Topics: Amputation, Traumatic; Blast Injuries; Civil Disorders; Contusions; Critical Care; Digestive System; | 1999 |
Protective effects of nitroglycerin-induced preconditioning mediated by calcitonin gene-related peptide in rat small intestine.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Gastrointesti | 2001 |
Intravenous nitroglycerin to improve coronary blood flow and left ventricular performance during vasopressin therapy.
Topics: Animals; Cardiac Output; Coronary Circulation; Dogs; Esophageal and Gastric Varices; Gastrointestina | 1979 |
Fatal torsade de pointes occurring in a patient receiving intravenous vasopressin and nitroglycerin.
Topics: Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Infusions, Intravenous; M | 1992 |
VP/NTG therapy in the patient with variceal bleeding.
Topics: Clinical Protocols; Critical Care; Drug Therapy, Combination; Esophageal and Gastric Varices; Female | 1990 |
Simultaneous infusion of nitroglycerin and nitroprusside to offset adverse effects of vasopressin during portosystemic shunting.
Topics: Adult; Aged; Coronary Disease; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Fe | 1989 |
Intravenous vasopressin and gastrointestinal hemorrhage in children.
Topics: Child; Drug Administration Schedule; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; | 1988 |
[Use of nitroglycerin in hemorrhages from varicose veins of the esophagus and stomach].
Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Nitroglycerin | 1985 |
Case studies of a clinical pharmacist.
Topics: Aged; Alcoholism; Allopurinol; Arrhythmias, Cardiac; Chloral Hydrate; Colchicine; Digoxin; Drug Syne | 1972 |