nitroglycerin has been researched along with Graft Occlusion, Vascular in 19 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a prospective, double-blind, randomized trial, we tested the effect of intravenous nitroglycerin on the incidence of angina and minor myocardial necrosis (MMN), as detected by cardiac troponin I increase, after elective coronary stenting." | 9.09 | A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000) |
| "We present a case of coronary artery vasospasm occurring during cardiac catheterization, which occurred while the patient was receiving substantial doses of intravenous nitroglycerin." | 7.67 | Coronary artery vasospasm during treatment with intravenous nitroglycerin. ( Brent, BN; Hom, GA, 1985) |
| " In a prospective, double-blind, randomized trial, we tested the effect of intravenous nitroglycerin on the incidence of angina and minor myocardial necrosis (MMN), as detected by cardiac troponin I increase, after elective coronary stenting." | 5.09 | A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000) |
| "We present a case of coronary artery vasospasm occurring during cardiac catheterization, which occurred while the patient was receiving substantial doses of intravenous nitroglycerin." | 3.67 | Coronary artery vasospasm during treatment with intravenous nitroglycerin. ( Brent, BN; Hom, GA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 11 (57.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshizaki, T | 1 |
| Tabuchi, N | 1 |
| Toyama, M | 1 |
| Castriota, F | 1 |
| Cremonesi, A | 1 |
| Manetti, R | 1 |
| Liso, A | 1 |
| Oshola, K | 1 |
| Ricci, E | 1 |
| Balestra, G | 1 |
| Muraki, S | 1 |
| Tsukamoto, M | 1 |
| Komatsu, K | 1 |
| Sakata, J | 1 |
| Ohori, S | 1 |
| Hasegawa, T | 1 |
| Abe, T | 1 |
| Ashar, V | 1 |
| Niccoli, G | 1 |
| Porto, I | 1 |
| Miwa, S | 1 |
| Desai, N | 1 |
| Koyama, T | 1 |
| Chan, E | 1 |
| Cohen, EA | 1 |
| Fremes, SE | 1 |
| Di Lazzaro, D | 1 |
| Ragni, T | 1 |
| Di Manici, G | 1 |
| Bardelli, G | 1 |
| Da Col, U | 1 |
| Grasselli, F | 1 |
| Antoniella, A | 1 |
| Papa, W | 1 |
| Crusco, F | 1 |
| Giovagnoni, A | 1 |
| Agostoni, P | 1 |
| Vermeersch, P | 1 |
| Vydt, T | 1 |
| Debrauwere, J | 1 |
| Van den Heuvel, P | 1 |
| Convens, C | 1 |
| Van den Branden, F | 1 |
| Verheye, S | 1 |
| Van Langenhove, G | 1 |
| Simon, R | 1 |
| Amende, I | 1 |
| Engel, HJ | 1 |
| Lichtlen, PR | 2 |
| Mügge, A | 1 |
| Heublein, B | 1 |
| Kuhn, M | 1 |
| Nolte, C | 1 |
| Haverich, A | 1 |
| Warnecke, J | 1 |
| Forssmann, WG | 1 |
| He, GW | 1 |
| Ryan, WH | 1 |
| Acuff, TE | 1 |
| Yang, CQ | 1 |
| Mack, MJ | 1 |
| Kaplan, BM | 1 |
| Benzuly, KH | 1 |
| Kinn, JW | 1 |
| Bowers, TR | 1 |
| Tilli, FV | 1 |
| Grines, CL | 1 |
| O'Neill, WW | 1 |
| Safian, RD | 1 |
| Kurz, DJ | 1 |
| Naegeli, B | 1 |
| Bertel, O | 1 |
| Chanda, J | 2 |
| Brichkov, I | 1 |
| Canver, CC | 2 |
| Gabe, ED | 1 |
| Figal, JC | 1 |
| Wisner, JN | 1 |
| Laguens, R | 1 |
| Tadjkarimi, S | 1 |
| O'Neil, GS | 1 |
| Luu, TN | 1 |
| Allen, SP | 1 |
| Schyns, CJ | 1 |
| Chester, AH | 1 |
| Yacoub, MH | 1 |
| Walsh, DB | 1 |
| Zwolak, RM | 1 |
| McDaniel, MD | 1 |
| Schneider, JR | 1 |
| Cronenwett, JL | 1 |
| Peduzzi, P | 1 |
| Hultgren, H | 1 |
| Thomsen, J | 1 |
| Detre, K | 1 |
| Hom, GA | 1 |
| Brent, BN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention[NCT02832115] | Phase 4 | 100 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in Radial artery cross sectional area in mm^2 - Before application of topical nitroglycerine / placebo (Pre dilation) vs Prior to arterial puncture after application of topical nitroglycerine / placebo (Post-dilation) (NCT02832115)
Timeframe: Application of nitroglycerine / placebo until prior to arterial puncture. Approximate 60 to 120 minutes
| Intervention | mm^2 (Mean) |
|---|---|
| Study | 2.5 |
| Control | -0.2 |
Need to abort procedure or convert to transfemoral access (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.
| Intervention | Participants (Count of Participants) |
|---|---|
| Study | 0 |
| Control | 4 |
Patient discomfort or pain during procedure measured using Visual analog scale 0-10, 0 being no discomfort or pain (best) and 10 being worst discomfort or pain (worst) (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.
| Intervention | score on a scale (Mean) |
|---|---|
| Study | 0.792 |
| Control | 0.875 |
"Incidence of radial artery spasm indicated by a Radial artery spasm score of 1 or more. Radial artery spasm score is sum of:~Intraprocedural pain in the forearm aggravated by movement of the catheter/sheath - Absent :0; Present:1~Difficulty in manipulating the catheter- Absence :0; Present:1~Difficulty with sheath removal: Absent: 0; Present:1~Additional use of intraarterial nitroglycerine or verapamil after the initial vasodilator cocktail- No:0; Yes:1" (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.
| Intervention | Participants (Count of Participants) |
|---|---|
| Study | 8 |
| Control | 15 |
Radial pulse at end of procedure 0- 4+, 0 indicating no palpable pulse (worst); 1 + indicating a faint, but detectable pulse; 2 + suggesting a slightly more diminished pulse than normal; 3 + is a normal pulse; and 4 + indicating a bounding pulse (best). (NCT02832115)
Timeframe: At the end of transradial cardiac catheterization after sheath removal
| Intervention | score on a scale (Mean) |
|---|---|
| Study | 2.208333333 |
| Control | 2.166666667 |
2 trials available for nitroglycerin and Graft Occlusion, Vascular
| Article | Year |
|---|---|
A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Coronary Disease; | 2000 |
Ten-year effect of medical and surgical therapy on quality of life: Veterans Administration Cooperative Study of Coronary Artery Surgery.
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Exercise Test; | 1987 |
17 other studies available for nitroglycerin and Graft Occlusion, Vascular
| Article | Year |
|---|---|
Verapamil and nitroglycerin improves the patency rate of radial artery grafts.
Topics: Administration, Topical; Aged; Coronary Artery Bypass; Drug Combinations; Female; Graft Occlusion, V | 2008 |
Impact of cerebral protection devices on early outcome of carotid stenting.
Topics: Aged; Blood Vessel Prosthesis Implantation; Carotid Artery, Common; Carotid Stenosis; Cerebrovascula | 2002 |
Minimally ischemic off-pump coronary artery bypass grafting: active perfusion-assist with nitroglycerin-supplemented blood.
Topics: Coronary Artery Bypass; Coronary Disease; Coronary Vessels; Female; Follow-Up Studies; Graft Occlusi | 2003 |
Diffuse saphenous vein graft spasm.
Topics: Angina Pectoris; Coronary Angiography; Coronary Artery Bypass; Follow-Up Studies; Graft Occlusion, V | 2004 |
Radial artery angiographic string sign: clinical consequences and the role of pharmacologic therapy.
Topics: Adrenergic alpha-Agonists; Anticoagulants; Aspirin; Blood Flow Velocity; Calcium Channel Blockers; C | 2006 |
Noninvasive midterm follow-up of radial artery bypass grafts with 16-slice computed tomography.
Topics: Coronary Angiography; Coronary Artery Bypass; Feasibility Studies; Female; Follow-Up Studies; Graft | 2006 |
Acute and mid-term local vascular effects of compliant balloon inflation (GuardWire system) on saphenous vein bypass grafts: an angiographic analysis.
Topics: Aged; Catheterization; Coronary Angiography; Coronary Artery Bypass; Coronary Stenosis; Coronary Ves | 2007 |
The effect of nitroglycerin and isosorbiddinitrate on myocardial perfusion and hemodynamics in patients with and without coronary disease.
Topics: Blood Flow Velocity; Blood Pressure; Cardiac Pacing, Artificial; Coronary Artery Bypass; Coronary Ci | 1984 |
Impaired coronary dilator responses to substance P and impaired flow-dependent dilator responses in heart transplant patients with graft vasculopathy.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Blood Platelets; Cardiac Catheterization; Coronary | 1993 |
Greater contractility of internal mammary artery bifurcation: possible cause of low patency rates.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Endothelins; Graft Occlusion, Va | 1994 |
Treatment of no-reflow in degenerated saphenous vein graft interventions: comparison of intracoronary verapamil and nitroglycerin.
Topics: Aged; Calcium Channel Blockers; Coronary Angiography; Coronary Artery Bypass; Female; Graft Occlusio | 1996 |
Prevention of radial artery graft vasospasm after coronary bypass.
Topics: Calcium Channel Blockers; Coronary Artery Bypass; Coronary Vasospasm; Culture Techniques; Dose-Respo | 2000 |
Radial artery graft vasospasm.
Topics: Coronary Angiography; Coronary Artery Bypass; Coronary Vasospasm; Graft Occlusion, Vascular; Humans; | 2001 |
Reversal of preexisting vasospasm in coronary artery conduits.
Topics: Arteries; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Di | 2001 |
Comparison of cyclic GMP in human internal mammary artery and saphenous vein: implications for coronary artery bypass graft patency.
Topics: Acetylcholine; Bradykinin; Coronary Artery Bypass; Culture Techniques; Cyclic GMP; Endothelium, Vasc | 1992 |
Intragraft drug infusion as an adjunct to balloon catheter thrombectomy for salvage of thrombosed infragenicular vein grafts: a preliminary report.
Topics: Aged; Blood Vessel Prosthesis; Catheterization; Female; Graft Occlusion, Vascular; Heparin; Humans; | 1990 |
Coronary artery vasospasm during treatment with intravenous nitroglycerin.
Topics: Angina Pectoris; Angina, Unstable; Cardiac Catheterization; Coronary Artery Bypass; Coronary Disease | 1985 |