Page last updated: 2024-11-01

nitroglycerin and Glaucoma

nitroglycerin has been researched along with Glaucoma in 11 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
" Nitroglycerin lowered intraocular pressure in all patients when administered by the perfusion technique."3.66Organic nitrate therapy in glaucoma. ( Wizemann, AJ; Wizemann, V, 1980)
"Intravenously administered nitroglycerin lowers intraocular pressure both in glaucoma patients and healthy subjects."3.66[The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)]. ( Wizemann, A; Wizemann, V, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acharya, S1
Rogers, P1
Krishnamoorthy, RR1
Stankowska, DL1
Dias, HV1
Yorio, T1
Shen, SC1
Ho, WJ1
Wu, SC1
Yu, KH1
Lin, HC1
Lin, YS1
Tsay, PK1
Chu, PH1
WHITWORTH, CG1
GRANT, WM1
Wizemann, AJ1
Wizemann, V2
Wizemann, A1
Wang, RF1
Podos, SM1
Leydhecker, W2
Saman, K1
Hradecká, V1
Brodehl, D1
Steinbach, PD1
Vrba, K1
Svejda, J1
Waller, W1
Krieglstein, G1

Other Studies

11 other studies available for nitroglycerin and Glaucoma

ArticleYear
Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy.
    Bioorganic & medicinal chemistry letters, 2016, Mar-01, Volume: 26, Issue:5

    Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Glaucoma; Humans; Hydrogen

2016
Peripheral vascular endothelial dysfunction in glaucomatocyclitic crisis: a preliminary study.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Autoantibodies; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brachial Arte

2010
USE OF NITRATE AND NITRITE VASODILATORS BY GLAUCOMATOUS PATIENTS.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 71

    Topics: Angina Pectoris; Glaucoma; Humans; Nitrates; Nitrites; Nitroglycerin; Toxicology; Vasodilator Agents

1964
Organic nitrate therapy in glaucoma.
    American journal of ophthalmology, 1980, Volume: 90, Issue:1

    Topics: Administration, Oral; Dose-Response Relationship, Drug; Glaucoma; Humans; Infusions, Parenteral; Int

1980
[The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 177, Issue:3

    Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Isosorbide Dinitrate; Nitr

1980
Effect of the topical application of nitroglycerin on intraocular pressure in normal and glaucomatous monkeys.
    Experimental eye research, 1995, Volume: 60, Issue:3

    Topics: Animals; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Nitroglycerin

1995
[Glaucoma and vasodilating agents].
    Deutsche medizinische Wochenschrift (1946), 1979, Sep-21, Volume: 104, Issue:38

    Topics: Glaucoma; Humans; Isosorbide Dinitrate; Nitroglycerin

1979
[Nitroglycerin and glaucoma].
    Ceskoslovenska oftalmologie, 1975, Volume: 31, Issue:6

    Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nitroglycerin

1975
[What is the effect of glyceryl trinitrate on the intraocular pressure? (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1975, Volume: 166, Issue:6

    Topics: Administration, Oral; Animals; Blood Pressure; Glaucoma; Humans; Injections, Intravenous; Intraocula

1975
[Is nitroglycerin contraindicated in glaucoma?].
    Vnitrni lekarstvi, 1986, Volume: 32, Issue:2

    Topics: Aged; Angina Pectoris; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Nitroglycerin

1986
[The effect of vasodilators on the intraocular pressure (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 164, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Benzyl Compounds; Blood Pressure; Cycloheptanes; D

1974