nitroglycerin has been researched along with Gastroesophageal Reflux in 8 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 7 patients who had significant gastroesophageal reflux associated with spasm, the response to nitroglycerine was unpredictable." | 2.64 | Esophageal spasm: clinical and manometric response to nitroglycerine and long acting nitrites. ( Swamy, N, 1977) |
| "Oesophageal spasm is a common empiric diagnosis clinically applied to patients with unexplained chest pain." | 2.43 | Review article: oesophageal spasm - diagnosis and management. ( Castell, DO; Tutuian, R, 2006) |
| "Chest pain is a common cause for referral to emergency departments." | 1.42 | A jackhammer in the gullet: high amplitude oesophageal contractions as a cause of atypical chest pain. ( Anggiansah, A; Goel, R; Wilkinson, M; Wong, T, 2015) |
| "Two of them had gastro-esophageal reflux." | 1.28 | [Nitroglycerin and angina with angiographically normal coronary vessels. Clinical effects and effects on esophageal motility]. ( Ducloux, G; Marquand, A; Millaire, A; Vaksmann, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goel, R | 1 |
| Anggiansah, A | 1 |
| Wong, T | 1 |
| Wilkinson, M | 1 |
| Tutuian, R | 1 |
| Castell, DO | 1 |
| Ferguson, SC | 1 |
| Hodges, K | 1 |
| Hersh, T | 1 |
| Jinich, H | 1 |
| Anselmino, M | 1 |
| Clark, GW | 1 |
| Hinder, RA | 1 |
| Lagergren, J | 1 |
| Bergström, R | 1 |
| Adami, HO | 1 |
| Nyrén, O | 1 |
| Swamy, N | 1 |
| Millaire, A | 1 |
| Ducloux, G | 1 |
| Marquand, A | 1 |
| Vaksmann, G | 1 |
| Pope, CE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Study To Define The Role Of Various Factors In Development And Progression Of Gastroesophageal Reflux Disease (GERD) And Barrett's Esophagus And The Creation Of A Registry.[NCT00574327] | 3,000 participants (Anticipated) | Observational | 2006-01-31 | Recruiting | |||
| Barrett's Esophagus Study (BEST) Trial - a Multi-Center and Endoscopic Outcomes Project[NCT00586404] | 1,250 participants (Actual) | Observational | 2007-11-30 | Terminated (stopped due to lack of enrollment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for nitroglycerin and Gastroesophageal Reflux
| Article | Year |
|---|---|
Review article: oesophageal spasm - diagnosis and management.
Topics: Administration, Oral; Antidepressive Agents; Botulinum Toxins; Calcium Channel Blockers; Chest Pain; | 2006 |
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E | 1993 |
Esophageal physiology.
Topics: Atropine; Barium Sulfate; Deglutition; Esophageal Achalasia; Esophageal Diseases; Esophagus; Gastrin | 1974 |
1 trial available for nitroglycerin and Gastroesophageal Reflux
| Article | Year |
|---|---|
Esophageal spasm: clinical and manometric response to nitroglycerine and long acting nitrites.
Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Esophageal Achalasia; Esophagus; Femal | 1977 |
4 other studies available for nitroglycerin and Gastroesophageal Reflux
| Article | Year |
|---|---|
A jackhammer in the gullet: high amplitude oesophageal contractions as a cause of atypical chest pain.
Topics: Anti-Ulcer Agents; Chest Pain; Esophageal Motility Disorders; Gastroesophageal Reflux; Humans; Male; | 2015 |
Esophageal Manometry in Patients with Chest Pain and Normal Coronary Arteriogram.
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Diagnosis, Differential; Esophageal Achalasia; Esop | 1981 |
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell; | 2000 |
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell; | 2000 |
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell; | 2000 |
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell; | 2000 |
[Nitroglycerin and angina with angiographically normal coronary vessels. Clinical effects and effects on esophageal motility].
Topics: Angina Pectoris; Chest Pain; Coronary Angiography; Ergonovine; Esophageal Motility Disorders; Esopha | 1989 |