Page last updated: 2024-11-01

nitroglycerin and Flushing

nitroglycerin has been researched along with Flushing in 4 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Flushing: A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine the effect of site of nitroglycerin ointment placement on headache and flushing in healthy subjects."9.07Effect of nitroglycerin ointment placement on headache and flushing in healthy subjects. ( Riegel, B; Shively, M, 1991)
"Fifty-six patients with cardiac disease participated in a study to determine the effect of site placement on patient reports of headache and flushing after topical nitroglycerin ointment placement."9.06Effect of nitroglycerin ointment placement on the severity of headache and flushing in patients with cardiac disease. ( Heywood, G; Jackson, W; Kennedy, A; Riegel, B, 1988)
"The purpose of this study was to determine the effect of site of nitroglycerin ointment placement on headache and flushing in healthy subjects."5.07Effect of nitroglycerin ointment placement on headache and flushing in healthy subjects. ( Riegel, B; Shively, M, 1991)
"Fifty-six patients with cardiac disease participated in a study to determine the effect of site placement on patient reports of headache and flushing after topical nitroglycerin ointment placement."5.06Effect of nitroglycerin ointment placement on the severity of headache and flushing in patients with cardiac disease. ( Heywood, G; Jackson, W; Kennedy, A; Riegel, B, 1988)
"Patients with a Crohn's disease activity index of > or = 150 and < 450 were randomized to receive 12 weeks of either glyceryl trinitrate (initially 6 mg twice daily, increasing to 9 mg twice daily after 6 weeks) or an identical placebo."2.70Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial. ( Ch'Ng, CL; Evans, BK; Green, JT; Hawkes, ND; Hawthorne, AB; Kingham, JG; Mayberry, JF; Rhodes, J; Rhodes, P; Richardson, C; Swift, GL; Thomas, GA; Williams, J, 2001)
"The third woman had migraine but the attacks were not associated with HS."1.38Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine. ( Goadsby, PJ; Mathias, CJ; Viana, M, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Viana, M1
Mathias, CJ1
Goadsby, PJ1
Hawkes, ND1
Richardson, C1
Ch'Ng, CL1
Green, JT1
Evans, BK1
Williams, J1
Rhodes, P1
Rhodes, J1
Swift, GL1
Thomas, GA1
Hawthorne, AB1
Kingham, JG1
Mayberry, JF1
Shively, M1
Riegel, B2
Heywood, G1
Jackson, W1
Kennedy, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Tolerability of Topical Nitroglycerin to Dilate the Radial Artery Prior to Transradial Coronary Angiography[NCT05239013]Early Phase 120 participants (Anticipated)Interventional2022-05-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for nitroglycerin and Flushing

ArticleYear
Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:12

    Topics: Administration, Oral; Adult; Crohn Disease; Dizziness; Double-Blind Method; Exanthema; Female; Flush

2001
Effect of nitroglycerin ointment placement on headache and flushing in healthy subjects.
    International journal of nursing studies, 1991, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Adult; Analysis of Variance; Angina Pectoris; Arm; Female; Flushing; Head

1991
Effect of nitroglycerin ointment placement on the severity of headache and flushing in patients with cardiac disease.
    Heart & lung : the journal of critical care, 1988, Volume: 17, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Coronary Disease; Female; Flu

1988

Other Studies

1 other study available for nitroglycerin and Flushing

ArticleYear
Headache in three new cases of Harlequin syndrome with accompanying pharmacological comparison with migraine.
    Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:6

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Diagnosis, Differential; Dihydroergotamine; Ergotami

2012