nitroglycerin has been researched along with Esophageal and Gastric Varices in 37 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Utilization data linked to the results of a double-blind, placebo-controlled trial demonstrating the efficacy of the terlipressin-glycerin trinitrate combination (TER-GTN) in the reduction of mortality at day 42 for haemorragic patients due to rupture of oesophageal varices." | 5.09 | Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients. ( Combier, E; de Pouvourville, G; Joseph, A; Letoumelin, P; Levacher, S; Pourriat, JL, 1999) |
| "Nitroglycerin dosage was not advanced appropriately in 78% of episodes despite evidence of bradycardia, hypertension and peripheral vasoconstriction." | 3.68 | Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding. ( Burns, SM; Luer, J; Martin, M; Merrill, P; Stone, DD, 1993) |
| "Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin." | 2.41 | The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000) |
| "Bleeding from esophageal varices presents a considerable challenge to clinicians." | 2.40 | Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination? ( Cello, JP, 1997) |
| "In conclusion, chronic administration of organic nitrates, allowing for a nitrate-free interval each day, to cirrhotic patients reduces portal pressure with a variable, dose-dependent effect on azygos blood flow." | 2.39 | Organic nitrates in portal hypertension. ( Hayes, PC; Jones, AL, 1994) |
| "Bleeding from esophagogastric varices carries a high mortality rate." | 2.38 | Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence. ( Marshall, JB, 1991) |
| "Bleeding from oesophageal varices is an uncommon but potentially fatal condition that often leads to expensive hospitalizations in intensive care or high-dependency units." | 1.29 | Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK. ( Bosanquet, N; Burroughs, AK; Greenslade, L; Matheson, LA; Matsaganis, M; McCormick, PA, 1995) |
| "In 40 patients with esophageal varices, esophageal variceal pressure was assessed endoscopically using a pneumatic pressure sensor." | 1.29 | Clinical significance of esophageal variceal pressure in patients with esophageal varices. ( Bandoh, T; Kitano, S; Kobayashi, M; Mitarai, Y; Yoshida, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (18.92) | 18.7374 |
| 1990's | 27 (72.97) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arguedas, MR | 1 |
| Kojima, K | 1 |
| Imazu, H | 1 |
| Matsumura, M | 1 |
| Honda, Y | 1 |
| Umemoto, N | 1 |
| Moriyasu, H | 1 |
| Orihashi, T | 1 |
| Uejima, M | 1 |
| Morioka, C | 1 |
| Komeda, Y | 1 |
| Uemura, M | 1 |
| Yoshiji, H | 1 |
| Fukui, H | 1 |
| McCormick, PA | 1 |
| Greenslade, L | 1 |
| Matheson, LA | 1 |
| Matsaganis, M | 1 |
| Bosanquet, N | 1 |
| Burroughs, AK | 2 |
| Avgerinos, A | 1 |
| Armonis, A | 1 |
| Sarin, SK | 2 |
| Saraya, A | 2 |
| Bandoh, T | 1 |
| Mitarai, Y | 1 |
| Kitano, S | 1 |
| Yoshida, T | 1 |
| Kobayashi, M | 1 |
| D'Amico, G | 1 |
| Traina, M | 1 |
| Vizzini, G | 1 |
| Tinè, F | 1 |
| Politi, F | 1 |
| Montalbano, L | 1 |
| Luca, A | 1 |
| Pasta, L | 1 |
| Pagliaro, L | 1 |
| Morabito, A | 1 |
| Dattani, BH | 1 |
| Troyer, SD | 1 |
| Truitt, CA | 1 |
| Jones, AL | 1 |
| Hayes, PC | 2 |
| Silvain, C | 2 |
| Carpentier, S | 1 |
| Sautereau, D | 2 |
| Czernichow, B | 1 |
| Métreau, JM | 1 |
| Fort, E | 2 |
| Ingrand, P | 2 |
| Boyer, J | 1 |
| Pillegand, B | 2 |
| Doffël, M | 1 |
| Burns, SM | 2 |
| Martin, M | 1 |
| Merrill, P | 1 |
| Luer, J | 1 |
| Stone, DD | 1 |
| Sanyal, AJ | 1 |
| Freedman, AM | 1 |
| Luketic, VA | 1 |
| Purdum, PP | 1 |
| Shiffman, ML | 1 |
| Tisnado, J | 1 |
| Cole, PE | 1 |
| Sugano, S | 1 |
| Suzuki, T | 1 |
| Nishio, M | 1 |
| Makino, H | 1 |
| Okajima, T | 1 |
| Cello, JP | 1 |
| Renner, EL | 1 |
| Eramishantsev, AK | 1 |
| Shertsinger, AG | 2 |
| Kitsenko, EA | 2 |
| Bour, AV | 1 |
| Bokhian, TS | 1 |
| Musin, RA | 1 |
| Nader, A | 1 |
| Grace, ND | 1 |
| Combier, E | 1 |
| Levacher, S | 1 |
| Letoumelin, P | 1 |
| Joseph, A | 1 |
| Pourriat, JL | 1 |
| de Pouvourville, G | 1 |
| Bosch, J | 3 |
| Bush, HL | 1 |
| Nabseth, DC | 1 |
| Matloff, DS | 1 |
| Jenkins, SA | 1 |
| Stein, LB | 1 |
| Dabezies, MA | 1 |
| Silverman, M | 1 |
| Brozena, SC | 1 |
| Iwao, T | 1 |
| Toyonaga, A | 1 |
| Ikegami, M | 1 |
| Sumino, M | 1 |
| Oho, K | 1 |
| Sakaki, M | 1 |
| Nishizono, M | 1 |
| Tanikawa, K | 1 |
| Marshall, JB | 1 |
| Söderlund, C | 1 |
| Eriksson, LS | 1 |
| Beauchant, M | 1 |
| Terés, J | 2 |
| Planas, R | 1 |
| Panes, J | 1 |
| Salmeron, JM | 1 |
| Mas, A | 2 |
| Llorente, C | 1 |
| Viver, J | 1 |
| Feu, F | 1 |
| Rodés, J | 2 |
| Martin, MJ | 1 |
| Sirinek, KR | 1 |
| Adcock, DK | 1 |
| Levine, BA | 1 |
| Westaby, D | 1 |
| Gimson, AE | 1 |
| Polson, RJ | 1 |
| Williams, R | 1 |
| Groszmann, RJ | 1 |
| García-Pagán, JC | 1 |
| García-Tsao, G | 1 |
| Navasa, M | 1 |
| Maier, KP | 1 |
| Staritz, M | 1 |
| Poralla, T | 1 |
| Meyer zum Büschenfelde, KH | 1 |
| Kuzin, GA | 1 |
| Nikitina, EA | 1 |
14 reviews available for nitroglycerin and Esophageal and Gastric Varices
| Article | Year |
|---|---|
The critically ill liver patient: the variceal bleeder.
Topics: Critical Illness; Diagnosis, Differential; Drug Therapy, Combination; Endoscopy, Gastrointestinal; E | 2003 |
Balloon tamponade technique and efficacy in variceal haemorrhage.
Topics: Balloon Occlusion; Catheterization; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hum | 1994 |
Nitroglycerin use in variceal hemorrhage.
Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Midd | 1994 |
Organic nitrates in portal hypertension.
Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans | 1994 |
Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination?
Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Hemosta | 1997 |
[Esophageal varices].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Combined Modality Therapy; Drug Therapy, Combi | 1997 |
Pharmacologic intervention during the acute bleeding episode.
Topics: Acute Disease; Antihypertensive Agents; Blood Flow Velocity; Drug Therapy, Combination; Esophageal a | 1999 |
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination | 2000 |
Treatment of acute variceal bleeding.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Drug Administration Schedule; Emergencies; Endosc | 1992 |
Acute management of bleeding oesophageal varices.
Topics: Acute Disease; Animals; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Esophageal an | 1992 |
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D | 1992 |
Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence.
Topics: Balloon Occlusion; Catheterization; Clinical Protocols; Education, Medical, Continuing; Endoscopy, G | 1991 |
Medical and surgical treatment of acute bleeding from esophageal varices in patients with cirrhosis.
Topics: Catheterization; Clinical Trials as Topic; Endoscopy, Gastrointestinal; Esophageal and Gastric Varic | 1991 |
[Drug treatment of bleeding esophageal varices. Acute therapy and prevention of recurrence].
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Drug Therapy, Combination; Esophageal and Gastr | 1986 |
12 trials available for nitroglycerin and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Effects of intravenous nitroglycerin and nitroglycerin and metoclopramide on intravariceal pressure: a double blind, randomized study.
Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Esophageal and Ga | 1995 |
Terlipressin or vasopressin plus transdermal nitroglycerin in a treatment strategy for digestive bleeding in cirrhosis. A randomized clinical trial. Liver Study Group of V. Cervello Hospital.
Topics: Administration, Cutaneous; Adult; Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; F | 1994 |
Effects of intravenous nitroglycerin and metoclopramide on intravariceal pressure: a double-blind, randomized study.
Topics: Adult; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Humans; Hyperten | 1993 |
Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: a multicenter randomized trial.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Drug Therapy, Combination; Emergencies; Esop | 1993 |
Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy.
Topics: Adult; Aged; Balloon Occlusion; Catheterization; Combined Modality Therapy; Emergencies; Esophageal | 1996 |
Chronic splanchnic hemodynamic effects of low-dose transdermal nitroglycerin versus low-dose transdermal nitroglycerin plus spironolactone in patients with cirrhosis.
Topics: Administration, Cutaneous; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Esopha | 1997 |
Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients.
Topics: Acute Disease; Antihypertensive Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Co | 1999 |
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D | 1992 |
A randomized trial of terlipressin plus nitroglycerin vs. balloon tamponade in the control of acute variceal hemorrhage.
Topics: Adult; Aged; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Emergencies; Esophageal | 1990 |
Vasopressin/nitroglycerin infusion vs. esophageal tamponade in the treatment of acute variceal bleeding: a randomized controlled trial.
Topics: Acute Disease; Adult; Aged; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Esophagea | 1990 |
Controlled clinical trial of injection sclerotherapy for active variceal bleeding.
Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Human | 1989 |
Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: a placebo-controlled clinical trial.
Topics: Administration, Cutaneous; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Dru | 1989 |
12 other studies available for nitroglycerin and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Sclerotherapy for gastric fundal variceal bleeding: is complete obliteration possible without cyanoacrylate?
Topics: Adult; Aged; Cyanoacrylates; Esophageal and Gastric Varices; Feasibility Studies; Female; Gastric Fu | 2005 |
Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK.
Topics: Acute Disease; Costs and Cost Analysis; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; | 1995 |
Clinical significance of esophageal variceal pressure in patients with esophageal varices.
Topics: Aged; Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; E | 1994 |
Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding.
Topics: Bradycardia; Clinical Protocols; Constriction, Pathologic; Drug Monitoring; Drug Therapy, Combinatio | 1993 |
[The conservative therapy of acute esophagogastric hemorrhages in portal hypertension patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Endosc | 1998 |
Intravenous nitroglycerin to improve coronary blood flow and left ventricular performance during vasopressin therapy.
Topics: Animals; Cardiac Output; Coronary Circulation; Dogs; Esophageal and Gastric Varices; Gastrointestina | 1979 |
Fatal torsade de pointes occurring in a patient receiving intravenous vasopressin and nitroglycerin.
Topics: Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Infusions, Intravenous; M | 1992 |
Portohepatic pressures, hepatic function, and blood gases in the combination of nitroglycerin and vasopressin: search for additive effects in cirrhotic portal hypertension.
Topics: Aged; Catheterization, Peripheral; Child; Drug Therapy, Combination; Esophageal and Gastric Varices; | 1992 |
VP/NTG therapy in the patient with variceal bleeding.
Topics: Clinical Protocols; Critical Care; Drug Therapy, Combination; Esophageal and Gastric Varices; Female | 1990 |
Simultaneous infusion of nitroglycerin and nitroprusside to offset adverse effects of vasopressin during portosystemic shunting.
Topics: Adult; Aged; Coronary Disease; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Fe | 1989 |
Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application.
Topics: Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; Esophag | 1985 |
[Use of nitroglycerin in hemorrhages from varicose veins of the esophagus and stomach].
Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Nitroglycerin | 1985 |