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nitroglycerin and Esophageal Varices

nitroglycerin has been researched along with Esophageal Varices in 37 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"Utilization data linked to the results of a double-blind, placebo-controlled trial demonstrating the efficacy of the terlipressin-glycerin trinitrate combination (TER-GTN) in the reduction of mortality at day 42 for haemorragic patients due to rupture of oesophageal varices."5.09Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients. ( Combier, E; de Pouvourville, G; Joseph, A; Letoumelin, P; Levacher, S; Pourriat, JL, 1999)
"Nitroglycerin dosage was not advanced appropriately in 78% of episodes despite evidence of bradycardia, hypertension and peripheral vasoconstriction."3.68Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding. ( Burns, SM; Luer, J; Martin, M; Merrill, P; Stone, DD, 1993)
"Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin."2.41The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000)
"Bleeding from esophageal varices presents a considerable challenge to clinicians."2.40Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination? ( Cello, JP, 1997)
"In conclusion, chronic administration of organic nitrates, allowing for a nitrate-free interval each day, to cirrhotic patients reduces portal pressure with a variable, dose-dependent effect on azygos blood flow."2.39Organic nitrates in portal hypertension. ( Hayes, PC; Jones, AL, 1994)
"Bleeding from esophagogastric varices carries a high mortality rate."2.38Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence. ( Marshall, JB, 1991)
"Bleeding from oesophageal varices is an uncommon but potentially fatal condition that often leads to expensive hospitalizations in intensive care or high-dependency units."1.29Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK. ( Bosanquet, N; Burroughs, AK; Greenslade, L; Matheson, LA; Matsaganis, M; McCormick, PA, 1995)
"In 40 patients with esophageal varices, esophageal variceal pressure was assessed endoscopically using a pneumatic pressure sensor."1.29Clinical significance of esophageal variceal pressure in patients with esophageal varices. ( Bandoh, T; Kitano, S; Kobayashi, M; Mitarai, Y; Yoshida, T, 1994)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19907 (18.92)18.7374
1990's27 (72.97)18.2507
2000's3 (8.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arguedas, MR1
Kojima, K1
Imazu, H1
Matsumura, M1
Honda, Y1
Umemoto, N1
Moriyasu, H1
Orihashi, T1
Uejima, M1
Morioka, C1
Komeda, Y1
Uemura, M1
Yoshiji, H1
Fukui, H1
McCormick, PA1
Greenslade, L1
Matheson, LA1
Matsaganis, M1
Bosanquet, N1
Burroughs, AK2
Avgerinos, A1
Armonis, A1
Sarin, SK2
Saraya, A2
Bandoh, T1
Mitarai, Y1
Kitano, S1
Yoshida, T1
Kobayashi, M1
D'Amico, G1
Traina, M1
Vizzini, G1
Tinè, F1
Politi, F1
Montalbano, L1
Luca, A1
Pasta, L1
Pagliaro, L1
Morabito, A1
Dattani, BH1
Troyer, SD1
Truitt, CA1
Jones, AL1
Hayes, PC2
Silvain, C2
Carpentier, S1
Sautereau, D2
Czernichow, B1
Métreau, JM1
Fort, E2
Ingrand, P2
Boyer, J1
Pillegand, B2
Doffël, M1
Burns, SM2
Martin, M1
Merrill, P1
Luer, J1
Stone, DD1
Sanyal, AJ1
Freedman, AM1
Luketic, VA1
Purdum, PP1
Shiffman, ML1
Tisnado, J1
Cole, PE1
Sugano, S1
Suzuki, T1
Nishio, M1
Makino, H1
Okajima, T1
Cello, JP1
Renner, EL1
Eramishantsev, AK1
Shertsinger, AG2
Kitsenko, EA2
Bour, AV1
Bokhian, TS1
Musin, RA1
Nader, A1
Grace, ND1
Combier, E1
Levacher, S1
Letoumelin, P1
Joseph, A1
Pourriat, JL1
de Pouvourville, G1
Bosch, J3
Bush, HL1
Nabseth, DC1
Matloff, DS1
Jenkins, SA1
Stein, LB1
Dabezies, MA1
Silverman, M1
Brozena, SC1
Iwao, T1
Toyonaga, A1
Ikegami, M1
Sumino, M1
Oho, K1
Sakaki, M1
Nishizono, M1
Tanikawa, K1
Marshall, JB1
Söderlund, C1
Eriksson, LS1
Beauchant, M1
Terés, J2
Planas, R1
Panes, J1
Salmeron, JM1
Mas, A2
Llorente, C1
Viver, J1
Feu, F1
Rodés, J2
Martin, MJ1
Sirinek, KR1
Adcock, DK1
Levine, BA1
Westaby, D1
Gimson, AE1
Polson, RJ1
Williams, R1
Groszmann, RJ1
García-Pagán, JC1
García-Tsao, G1
Navasa, M1
Maier, KP1
Staritz, M1
Poralla, T1
Meyer zum Büschenfelde, KH1
Kuzin, GA1
Nikitina, EA1

Reviews

14 reviews available for nitroglycerin and Esophageal Varices

ArticleYear
The critically ill liver patient: the variceal bleeder.
    Seminars in gastrointestinal disease, 2003, Volume: 14, Issue:1

    Topics: Critical Illness; Diagnosis, Differential; Drug Therapy, Combination; Endoscopy, Gastrointestinal; E

2003
Balloon tamponade technique and efficacy in variceal haemorrhage.
    Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 207

    Topics: Balloon Occlusion; Catheterization; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hum

1994
Nitroglycerin use in variceal hemorrhage.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:2

    Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Midd

1994
Organic nitrates in portal hypertension.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:1

    Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans

1994
Endoscopic management of esophageal variceal hemorrhage: injection, banding, glue, octreotide, or a combination?
    Seminars in gastrointestinal disease, 1997, Volume: 8, Issue:4

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Hemosta

1997
[Esophageal varices].
    Therapeutische Umschau. Revue therapeutique, 1997, Volume: 54, Issue:11

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Combined Modality Therapy; Drug Therapy, Combi

1997
Pharmacologic intervention during the acute bleeding episode.
    Gastrointestinal endoscopy clinics of North America, 1999, Volume: 9, Issue:2

    Topics: Acute Disease; Antihypertensive Agents; Blood Flow Velocity; Drug Therapy, Combination; Esophageal a

1999
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination

2000
Treatment of acute variceal bleeding.
    Gastroenterology clinics of North America, 1992, Volume: 21, Issue:1

    Topics: Acute Disease; Balloon Occlusion; Catheterization; Drug Administration Schedule; Emergencies; Endosc

1992
Acute management of bleeding oesophageal varices.
    Drugs, 1992, Volume: 44 Suppl 2

    Topics: Acute Disease; Animals; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Esophageal an

1992
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
    Drugs, 1992, Volume: 44 Suppl 2

    Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D

1992
Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence.
    Postgraduate medicine, 1991, May-01, Volume: 89, Issue:6

    Topics: Balloon Occlusion; Catheterization; Clinical Protocols; Education, Medical, Continuing; Endoscopy, G

1991
Medical and surgical treatment of acute bleeding from esophageal varices in patients with cirrhosis.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:9

    Topics: Catheterization; Clinical Trials as Topic; Endoscopy, Gastrointestinal; Esophageal and Gastric Varic

1991
[Drug treatment of bleeding esophageal varices. Acute therapy and prevention of recurrence].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-21, Volume: 111, Issue:8

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Drug Therapy, Combination; Esophageal and Gastr

1986

Trials

12 trials available for nitroglycerin and Esophageal Varices

ArticleYear
Effects of intravenous nitroglycerin and nitroglycerin and metoclopramide on intravariceal pressure: a double blind, randomized study.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Esophageal and Ga

1995
Terlipressin or vasopressin plus transdermal nitroglycerin in a treatment strategy for digestive bleeding in cirrhosis. A randomized clinical trial. Liver Study Group of V. Cervello Hospital.
    Journal of hepatology, 1994, Volume: 20, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; F

1994
Effects of intravenous nitroglycerin and metoclopramide on intravariceal pressure: a double-blind, randomized study.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:11

    Topics: Adult; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Humans; Hyperten

1993
Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: a multicenter randomized trial.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Drug Therapy, Combination; Emergencies; Esop

1993
Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy.
    Gastroenterology, 1996, Volume: 111, Issue:1

    Topics: Adult; Aged; Balloon Occlusion; Catheterization; Combined Modality Therapy; Emergencies; Esophageal

1996
Chronic splanchnic hemodynamic effects of low-dose transdermal nitroglycerin versus low-dose transdermal nitroglycerin plus spironolactone in patients with cirrhosis.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:3

    Topics: Administration, Cutaneous; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Esopha

1997
Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients.
    Intensive care medicine, 1999, Volume: 25, Issue:4

    Topics: Acute Disease; Antihypertensive Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Co

1999
Somatostatin in acute bleeding oesophageal varices. Clinical evidence.
    Drugs, 1992, Volume: 44 Suppl 2

    Topics: Acute Disease; Balloon Occlusion; Catheterization; Combined Modality Therapy; Double-Blind Method; D

1992
A randomized trial of terlipressin plus nitroglycerin vs. balloon tamponade in the control of acute variceal hemorrhage.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: Adult; Aged; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Emergencies; Esophageal

1990
Vasopressin/nitroglycerin infusion vs. esophageal tamponade in the treatment of acute variceal bleeding: a randomized controlled trial.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6

    Topics: Acute Disease; Adult; Aged; Balloon Occlusion; Catheterization; Drug Therapy, Combination; Esophagea

1990
Controlled clinical trial of injection sclerotherapy for active variceal bleeding.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:2

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Human

1989
Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: a placebo-controlled clinical trial.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:6

    Topics: Administration, Cutaneous; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Dru

1989

Other Studies

12 other studies available for nitroglycerin and Esophageal Varices

ArticleYear
Sclerotherapy for gastric fundal variceal bleeding: is complete obliteration possible without cyanoacrylate?
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:11

    Topics: Adult; Aged; Cyanoacrylates; Esophageal and Gastric Varices; Feasibility Studies; Female; Gastric Fu

2005
Vasoconstrictors in the management of bleeding from oesophageal varices. A clinico-economic appraisal in the UK.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:4

    Topics: Acute Disease; Costs and Cost Analysis; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage;

1995
Clinical significance of esophageal variceal pressure in patients with esophageal varices.
    Journal of hepatology, 1994, Volume: 21, Issue:3

    Topics: Aged; Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; E

1994
Evaluation and revision of a vasopressin/nitroglycerin protocol for use in variceal bleeding.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 1993, Volume: 2, Issue:3

    Topics: Bradycardia; Clinical Protocols; Constriction, Pathologic; Drug Monitoring; Drug Therapy, Combinatio

1993
[The conservative therapy of acute esophagogastric hemorrhages in portal hypertension patients].
    Klinicheskaia meditsina, 1998, Volume: 76, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Endosc

1998
Intravenous nitroglycerin to improve coronary blood flow and left ventricular performance during vasopressin therapy.
    Surgical forum, 1979, Volume: 30

    Topics: Animals; Cardiac Output; Coronary Circulation; Dogs; Esophageal and Gastric Varices; Gastrointestina

1979
Fatal torsade de pointes occurring in a patient receiving intravenous vasopressin and nitroglycerin.
    Journal of clinical gastroenterology, 1992, Volume: 15, Issue:2

    Topics: Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Infusions, Intravenous; M

1992
Portohepatic pressures, hepatic function, and blood gases in the combination of nitroglycerin and vasopressin: search for additive effects in cirrhotic portal hypertension.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:6

    Topics: Aged; Catheterization, Peripheral; Child; Drug Therapy, Combination; Esophageal and Gastric Varices;

1992
VP/NTG therapy in the patient with variceal bleeding.
    Critical care nurse, 1990, Volume: 10, Issue:9

    Topics: Clinical Protocols; Critical Care; Drug Therapy, Combination; Esophageal and Gastric Varices; Female

1990
Simultaneous infusion of nitroglycerin and nitroprusside to offset adverse effects of vasopressin during portosystemic shunting.
    American journal of surgery, 1989, Volume: 157, Issue:1

    Topics: Adult; Aged; Coronary Disease; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Fe

1989
Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application.
    Gut, 1985, Volume: 26, Issue:5

    Topics: Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; Esophag

1985
[Use of nitroglycerin in hemorrhages from varicose veins of the esophagus and stomach].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:11

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Nitroglycerin

1985