nitroglycerin has been researched along with Endotoxemia in 6 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
Excerpt | Relevance | Reference |
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"In a randomized, placebo-controlled, parallel group study, forearm blood flow (FBF) responses to NE, ACh, and the endothelium-independent vasodilator nitroglycerin (NTG) were assessed at baseline, after 4 days of simvastatin 80 mg PO or placebo treatment, and during Escherichia coli endotoxin (lipopolysaccharide [LPS])-induced inflammation in 20 healthy volunteers." | 9.11 | Simvastatin prevents vascular hyporeactivity during inflammation. ( Kapiotis, S; Marsik, C; Mittermayer, F; Pleiner, J; Polterauer, S; Schaller, G; Wolzt, M; Zorn, S, 2004) |
"In a randomized, placebo-controlled, parallel group study, forearm blood flow (FBF) responses to NE, ACh, and the endothelium-independent vasodilator nitroglycerin (NTG) were assessed at baseline, after 4 days of simvastatin 80 mg PO or placebo treatment, and during Escherichia coli endotoxin (lipopolysaccharide [LPS])-induced inflammation in 20 healthy volunteers." | 5.11 | Simvastatin prevents vascular hyporeactivity during inflammation. ( Kapiotis, S; Marsik, C; Mittermayer, F; Pleiner, J; Polterauer, S; Schaller, G; Wolzt, M; Zorn, S, 2004) |
"1." | 1.35 | Effects of 1400W and/or nitroglycerin on renal oxygenation and kidney function during endotoxaemia in anaesthetized rats. ( Dieterich, HJ; Goedhart, PT; Ince, C; Johannes, T; Klingel, K; Mik, EG; Nohé, B; Unertl, KE; Zanke, C, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 4 (66.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cox, LA | 1 |
van Eijk, LT | 1 |
Ramakers, BP | 1 |
Dorresteijn, MJ | 1 |
Gerretsen, J | 1 |
Kox, M | 1 |
Pickkers, P | 1 |
Johannes, T | 1 |
Mik, EG | 1 |
Klingel, K | 1 |
Goedhart, PT | 1 |
Zanke, C | 1 |
Nohé, B | 1 |
Dieterich, HJ | 1 |
Unertl, KE | 1 |
Ince, C | 1 |
Evans, RG | 1 |
May, CN | 1 |
Pleiner, J | 1 |
Schaller, G | 1 |
Mittermayer, F | 1 |
Zorn, S | 1 |
Marsik, C | 1 |
Polterauer, S | 1 |
Kapiotis, S | 1 |
Wolzt, M | 1 |
Kozlov, AV | 1 |
Albrecht, M | 1 |
Donnelly, EM | 1 |
Jafarmadar, M | 1 |
Szelenyi, Z | 1 |
Nohl, H | 1 |
Redl, H | 1 |
Bahrami, S | 1 |
Inan, M | 1 |
Sayek, I | 1 |
Tel, BC | 1 |
Sahin-Erdemli, I | 1 |
2 trials available for nitroglycerin and Endotoxemia
Article | Year |
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Inflammation-induced increases in plasma endocan levels are associated with endothelial dysfunction in humans in vivo.
Topics: Adult; Blood Flow Velocity; Endothelium, Vascular; Endotoxemia; Forearm; Healthy Volunteers; Humans; | 2015 |
Simvastatin prevents vascular hyporeactivity during inflammation.
Topics: Acetylcholine; Adult; Double-Blind Method; Endotoxemia; Endotoxins; Forearm; Humans; Inflammation; M | 2004 |
4 other studies available for nitroglycerin and Endotoxemia
Article | Year |
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Effects of 1400W and/or nitroglycerin on renal oxygenation and kidney function during endotoxaemia in anaesthetized rats.
Topics: Acute Kidney Injury; Amidines; Anesthesia, General; Animals; Benzylamines; Biomarkers; Creatinine; D | 2009 |
Tissue hypoxia as a therapeutic target in acute kidney injury.
Topics: Acute Kidney Injury; Amidines; Animals; Benzylamines; Endotoxemia; Enzyme Inhibitors; Kidney; Male; | 2009 |
Release and hemodynamic influence of nitro-glycerine-derived nitric oxide in endotoxemic rats.
Topics: Animals; Blood Pressure; Chelating Agents; Ditiocarb; Electron Spin Resonance Spectroscopy; Endotoxe | 2005 |
Role of endotoxin and nitric oxide in the pathogenesis of renal failure in obstructive jaundice.
Topics: Acetylcholine; Acute Kidney Injury; Animals; Bile Ducts; Bilirubin; Blood Pressure; Cholestasis; Col | 1997 |