nitroglycerin has been researched along with Dyspnea in 30 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Dyspnea: Difficult or labored breathing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vasodilators, such as nitroglycerin, have long been first-line treatments for acute heart failure syndromes (AHFS)." | 9.24 | Intravenous nicorandil for treatment of the urgent phase acute heart failure syndromes: A randomized, controlled trial. ( Fujinaga, H; Fujisawa, K; Harada, K; Harada, T; Iima, T; Kageyama, N; Kawata, A; Okada, A; Okumura, T; Saito, A; Shigekiyo, M; Terada, N; Yamamoto, H; Yamamoto, T, 2017) |
| "Cardiac output (CO) change with sublingual nitroglycerin (NTG) could be helpful in the diagnosis of HF in patients with acute undifferentiated dyspnea." | 8.02 | Value of nitroglycerin test in the diagnosis of heart failure in emergency department patients with undifferentiated dyspnea. ( Asma, Z; Bel Haj Ali, K; Beltaief, K; Ben Brahim, N; Ben Soltane, H; Boubaker, H; Bouida, W; Bzeouich, N; Gannoun, I; Grissa, MH; Jeddi, C; Laouiti, K; Lotfi, B; Mariem, K; Msolli, MA; Nouira, S; Riadh, B; Rym, Y; Sekma, A; Trabelssi, I; Zied, M; Zohra, D, 2021) |
| "In 12 patients with coronary heart disease and increased left ventricular filling pressure the pressure lowering effect of an oral long-acting nitroglycerin preparation (Sustac-Retard forte) was investigated at rest (n = 6) and during exercise (n = 6)." | 7.65 | [Action of sustained release nitroglycerin on a pulmonary artery pressure in coronary heart disease (author's transl)]. ( Hochrein, H; Volkmer, F, 1977) |
| "In 15 patients with left ventricular failure, ten with recent myocardial infarction and five with old infarct a highly significant fall in pulmonary-artery pressure occurred within 3-5 minutes of sublingual administration of nitroglycerine, 0." | 7.65 | [Effect of nitroglycerine in acute myocardial infarction: I: Sublingual nitroglycerine in the treatment of left-heart failure and pulmonary oedema (author's transl)]. ( Bussmann, WD; Kaltenbach, M; Vachalowa, J, 1975) |
| "Decompensated congestive heart failure (CHF) is the leading hospital discharge diagnosis in patients older than 65 years." | 6.70 | Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. ( , 2002) |
| " Although there are Free Open Access Medical Education (FOAM) based podcasts as well as few studies to suggest the use of HDN, the evidence is limited by statistical flaws, incomplete dosing parameters and inconsistent methods of administration." | 5.48 | Recognition of Sympathetic Crashing Acute Pulmonary Edema (SCAPE) and use of high-dose nitroglycerin infusion. ( Clarkson, L; Paone, S; Punnapuzha, S; Sin, B, 2018) |
| "Vasodilators, such as nitroglycerin, have long been first-line treatments for acute heart failure syndromes (AHFS)." | 5.24 | Intravenous nicorandil for treatment of the urgent phase acute heart failure syndromes: A randomized, controlled trial. ( Fujinaga, H; Fujisawa, K; Harada, K; Harada, T; Iima, T; Kageyama, N; Kawata, A; Okada, A; Okumura, T; Saito, A; Shigekiyo, M; Terada, N; Yamamoto, H; Yamamoto, T, 2017) |
| "Cardiac output (CO) change with sublingual nitroglycerin (NTG) could be helpful in the diagnosis of HF in patients with acute undifferentiated dyspnea." | 4.02 | Value of nitroglycerin test in the diagnosis of heart failure in emergency department patients with undifferentiated dyspnea. ( Asma, Z; Bel Haj Ali, K; Beltaief, K; Ben Brahim, N; Ben Soltane, H; Boubaker, H; Bouida, W; Bzeouich, N; Gannoun, I; Grissa, MH; Jeddi, C; Laouiti, K; Lotfi, B; Mariem, K; Msolli, MA; Nouira, S; Riadh, B; Rym, Y; Sekma, A; Trabelssi, I; Zied, M; Zohra, D, 2021) |
| " Compared to group 2, group 1 patients more frequently had exercise-induced dyspnea, and had a greater maximum ST-segment depression and a lower coronary blood flow response to adenosine and cold pressor test, but group 2 patients had a more frequent history of rest angina." | 3.88 | Microvascular Angina - Long-Term Exercise Stress Test Follow-up. ( Crea, F; De Vita, A; Filice, M; Lamendola, P; Lanza, GA; Manfredonia, L; Villano, A, 2018) |
| "In 12 patients with coronary heart disease and increased left ventricular filling pressure the pressure lowering effect of an oral long-acting nitroglycerin preparation (Sustac-Retard forte) was investigated at rest (n = 6) and during exercise (n = 6)." | 3.65 | [Action of sustained release nitroglycerin on a pulmonary artery pressure in coronary heart disease (author's transl)]. ( Hochrein, H; Volkmer, F, 1977) |
| "In 15 patients with left ventricular failure, ten with recent myocardial infarction and five with old infarct a highly significant fall in pulmonary-artery pressure occurred within 3-5 minutes of sublingual administration of nitroglycerine, 0." | 3.65 | [Effect of nitroglycerine in acute myocardial infarction: I: Sublingual nitroglycerine in the treatment of left-heart failure and pulmonary oedema (author's transl)]. ( Bussmann, WD; Kaltenbach, M; Vachalowa, J, 1975) |
| "Decompensated congestive heart failure (CHF) is the leading hospital discharge diagnosis in patients older than 65 years." | 2.70 | Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. ( , 2002) |
| " New insight has been gained regarding volume management, including dosing strategies for intravenous loop diuretics and the role of ultrafiltration in patients with heart failure and renal dysfunction." | 2.49 | Acute decompensated heart failure: update on new and emerging evidence and directions for future research. ( Albert, NM; Butler, J; Carson, PE; Collins, SP; Colvin-Adams, M; Dimarco, JP; Ezekowitz, JA; Fang, JC; Givertz, MM; Hernandez, AF; Hershberger, RE; Katz, SD; Krishnamani, R; Rogers, JG; Spertus, JA; Starling, RC; Stevenson, WG; Stough, WG; Sweitzer, NK; Tang, WH; Teerlink, JR; Walsh, MN; Westlake Canary, CA, 2013) |
| "Myocardial infarction is common among the elderly." | 2.39 | Myocardial infarction. Considerations for geriatric patients. ( Sinclair, D, 1994) |
| "74%, respectively) and rales (56% vs." | 1.48 | Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial. ( Ambrosy, AP; Armstrong, PW; Butler, J; Cerbin, LP; Coles, A; DeVore, AD; Ezekowitz, JA; Greene, SJ; Hernandez, AF; Mentz, RJ; Metra, M; O'Connor, CM; Starling, RC; Tang, W; Teerlink, JR; Voors, AA; Wu, A, 2018) |
| " Although there are Free Open Access Medical Education (FOAM) based podcasts as well as few studies to suggest the use of HDN, the evidence is limited by statistical flaws, incomplete dosing parameters and inconsistent methods of administration." | 1.48 | Recognition of Sympathetic Crashing Acute Pulmonary Edema (SCAPE) and use of high-dose nitroglycerin infusion. ( Clarkson, L; Paone, S; Punnapuzha, S; Sin, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (33.33) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 12 (40.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hodroge, SS | 1 |
| Glenn, M | 1 |
| Breyre, A | 1 |
| Lee, B | 1 |
| Aldridge, NR | 1 |
| Sporer, KA | 1 |
| Koenig, KL | 1 |
| Gausche-Hill, M | 1 |
| Salvucci, AA | 1 |
| Rudnick, EM | 1 |
| Brown, JF | 1 |
| Gilbert, GH | 1 |
| Sekma, A | 1 |
| Bel Haj Ali, K | 1 |
| Jeddi, C | 1 |
| Ben Brahim, N | 1 |
| Bzeouich, N | 1 |
| Gannoun, I | 1 |
| Trabelssi, I | 1 |
| Laouiti, K | 1 |
| Grissa, MH | 1 |
| Beltaief, K | 1 |
| Zohra, D | 1 |
| Asma, Z | 1 |
| Lotfi, B | 1 |
| Rym, Y | 1 |
| Ben Soltane, H | 1 |
| Zied, M | 1 |
| Mariem, K | 1 |
| Msolli, MA | 1 |
| Riadh, B | 1 |
| Bouida, W | 1 |
| Boubaker, H | 1 |
| Nouira, S | 1 |
| Lanza, GA | 1 |
| Filice, M | 1 |
| De Vita, A | 1 |
| Villano, A | 1 |
| Manfredonia, L | 1 |
| Lamendola, P | 1 |
| Crea, F | 1 |
| Cerbin, LP | 1 |
| Ambrosy, AP | 1 |
| Greene, SJ | 1 |
| Armstrong, PW | 1 |
| Butler, J | 2 |
| Coles, A | 1 |
| DeVore, AD | 1 |
| Ezekowitz, JA | 2 |
| Hernandez, AF | 2 |
| Metra, M | 1 |
| Starling, RC | 2 |
| Tang, W | 1 |
| Teerlink, JR | 2 |
| Voors, AA | 1 |
| Wu, A | 1 |
| O'Connor, CM | 1 |
| Mentz, RJ | 1 |
| Paone, S | 1 |
| Clarkson, L | 1 |
| Sin, B | 1 |
| Punnapuzha, S | 1 |
| Givertz, MM | 1 |
| Albert, NM | 1 |
| Westlake Canary, CA | 1 |
| Collins, SP | 1 |
| Colvin-Adams, M | 1 |
| Fang, JC | 1 |
| Katz, SD | 1 |
| Krishnamani, R | 1 |
| Stough, WG | 1 |
| Walsh, MN | 1 |
| Carson, PE | 1 |
| Dimarco, JP | 1 |
| Hershberger, RE | 1 |
| Rogers, JG | 1 |
| Spertus, JA | 1 |
| Stevenson, WG | 1 |
| Sweitzer, NK | 1 |
| Tang, WH | 1 |
| Figueras, J | 1 |
| Domingo, E | 1 |
| Ferreira, I | 1 |
| Lidón, RM | 1 |
| Bellera, N | 1 |
| Garcia-Dorado, D | 1 |
| Harada, K | 1 |
| Yamamoto, T | 1 |
| Okumura, T | 1 |
| Shigekiyo, M | 1 |
| Terada, N | 1 |
| Okada, A | 1 |
| Kawata, A | 1 |
| Iima, T | 1 |
| Harada, T | 1 |
| Fujisawa, K | 1 |
| Kageyama, N | 1 |
| Saito, A | 1 |
| Yamamoto, H | 1 |
| Fujinaga, H | 1 |
| Wen, S | 1 |
| Ning, J | 1 |
| Collins, S | 1 |
| Berry, D | 1 |
| Gläser, S | 1 |
| Obst, A | 1 |
| Opitz, CF | 1 |
| Dörr, M | 1 |
| Felix, SB | 1 |
| Empen, K | 1 |
| Völzke, H | 1 |
| Ewert, R | 1 |
| Schäper, C | 1 |
| Koch, B | 1 |
| Squiccimarro, G | 1 |
| Carrabba, M | 1 |
| Hu, C | 1 |
| Cappellini, MD | 1 |
| Fabio, G | 1 |
| Anand, A | 1 |
| Srivastava, N | 1 |
| Raj, H | 1 |
| Odunukan, OW | 1 |
| Abudiab, MM | 1 |
| Sinak, LJ | 1 |
| REAL, AP | 1 |
| Lewis, E | 1 |
| Stacey, MR | 1 |
| Sinclair, D | 1 |
| Jackson, G | 1 |
| Gavaghan, BJ | 1 |
| Kittleson, MD | 1 |
| Shinohara, T | 1 |
| Yanai, H | 1 |
| Hidaka, T | 1 |
| Suzuki, K | 1 |
| Ohsuzu, F | 1 |
| Bussmann, WD | 3 |
| Schupp, D | 2 |
| Volkmer, F | 1 |
| Hochrein, H | 1 |
| Kennedy, HL | 1 |
| Underhill, SJ | 1 |
| Vachalowa, J | 1 |
| Kaltenbach, M | 1 |
| Wolf, PS | 1 |
| Reynolds, JL | 1 |
| Whitlock, RM | 1 |
| Powell, WJ | 1 |
| Whiting, RB | 1 |
| Dinsmore, RE | 1 |
| Sanders, CA | 1 |
| Pepne, CJ | 1 |
| Schang, SJ | 1 |
| Bemiller, CR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Nesiritide in the Management of Acute Diastolic Heart Failure[NCT00083772] | Phase 4 | 9 participants (Actual) | Interventional | 2004-05-17 | Terminated | ||
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Hemodynamic and Clinical Effects of Natrecor (Nesiritide) Compared With Nitroglycerin Therapy for Symptomatic Decompensated CHF, The VMAC Trial: Vasodilation in the Management of Acu[NCT00270374] | Phase 3 | 498 participants (Actual) | Interventional | 1999-10-31 | Completed | ||
| Double Blind Randomized Placebo Controlled Trial of Natrecor in Patients Hospitalized for Decompensated Heart Failure in the Presence of a Normal Left Ventricular Ejection Fraction[NCT00505791] | Phase 4 | 0 participants (Actual) | Interventional | 2007-08-31 | Withdrawn (stopped due to Unable to enroll patients) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitroglycerin and Dyspnea
| Article | Year |
|---|---|
Acute decompensated heart failure: update on new and emerging evidence and directions for future research.
Topics: Adrenomedullin; Atrial Natriuretic Factor; Biomarkers; Blood Pressure Monitoring, Ambulatory; Cardio | 2013 |
Acute heart failure with dyspnoea: initial treatment. Furosemide and trinitrine, despite the lack of a proven survival benefit.
Topics: Acute Disease; Blood Pressure; Diuretics; Dyspnea; Furosemide; Heart Failure; Nitroglycerin; Vasodil | 2011 |
Myocardial infarction. Considerations for geriatric patients.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; A | 1994 |
Cardiac asthma--its origin, recognition and management.
Topics: Airway Resistance; Aminophylline; Animals; Bronchial Spasm; Digitalis Glycosides; Diuretics; Dyspnea | 1976 |
6 trials available for nitroglycerin and Dyspnea
| Article | Year |
|---|---|
Intravenous nicorandil for treatment of the urgent phase acute heart failure syndromes: A randomized, controlled trial.
Topics: Administration, Intravenous; Aged; Aged, 80 and over; Diastole; Dyspnea; Echocardiography; Emergency | 2017 |
A response-adaptive design of initial therapy for emergency department patients with heart failure.
Topics: Acute Disease; Bayes Theorem; Blood Pressure; Diuretics; Dyspnea; Emergency Service, Hospital; Furos | 2017 |
Effect of sublingual nitrate on respiratory reflexes arising from stimulation of juxta-pulmonary capillary (J) receptors by i.v. lobeline and short duration exercise.
Topics: Adaptation, Physiological; Administration, Sublingual; Adult; Blood Pressure; Dose-Response Relation | 2012 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Cardiotonic Agents; Double-Blind Method; Drug Thera | 2002 |
Effects of a beta-adrenergic receptor blocker in myocardial infarction treated for one year from onset.
Topics: Alprenolol; Amino Alcohols; Angina Pectoris; Blood Pressure; Cardiac Complexes, Premature; Clinical | 1972 |
Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis; Blood Pressure; Catheterization; Clinical Trials as | 1974 |
20 other studies available for nitroglycerin and Dyspnea
| Article | Year |
|---|---|
Adult Patients with Respiratory Distress: Current Evidence-based Recommendations for Prehospital Care.
Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; California; Dyspnea; Emergency Medical Services; Ho | 2020 |
Value of nitroglycerin test in the diagnosis of heart failure in emergency department patients with undifferentiated dyspnea.
Topics: Acute Disease; Dyspnea; Emergency Service, Hospital; Heart Failure; Humans; Natriuretic Peptide, Bra | 2021 |
Microvascular Angina - Long-Term Exercise Stress Test Follow-up.
Topics: Adenosine; Adult; Coronary Circulation; Dyspnea; Electrocardiography; Exercise Test; Female; Follow- | 2018 |
Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.
Topics: Acute Disease; After-Hours Care; Aged; Dyspnea; Emergency Service, Hospital; Female; Heart Failure; | 2018 |
Recognition of Sympathetic Crashing Acute Pulmonary Edema (SCAPE) and use of high-dose nitroglycerin infusion.
Topics: Aged, 80 and over; Atrial Fibrillation; Clinical Protocols; Dyspnea; Humans; Hypertension; Infusion | 2018 |
Typical angina without significant coronary stenosis: comparison of clinical profile, circadian presentation, and long-term follow-up between patients with and patients without vasospastic angina.
Topics: Adult; Chi-Square Distribution; Circadian Rhythm; Coronary Angiography; Coronary Vasospasm; Diabetes | 2013 |
Peripheral endothelial dysfunction is associated with gas exchange inefficiency in smokers.
Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Chi-Square Distribution; Cross-Sectional Studies; D | 2011 |
What does acute dyspnea hide?
Topics: Acute Disease; Anti-Bacterial Agents; Bronchiolitis Obliterans; Diagnosis, Differential; Dyspnea; Hu | 2012 |
48-year-old man with cough and leg swelling.
Topics: Acute Disease; Antihypertensive Agents; Cerebrovascular Circulation; Cough; Dyspnea; Echocardiograph | 2012 |
[Nebulization of trinitrin in dyspneic episodes of left cardiac insufficiency].
Topics: Dyspnea; Heart Failure; Humans; Nitrites; Nitroglycerin | 1956 |
Cardiorespiratory symptoms in pregnancy: not always pulmonary embolism.
Topics: Cardiomyopathies; Cesarean Section; Chest Pain; Diagnosis, Differential; Diuretics; Dyspnea; Echocar | 2007 |
The management of stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angioplasty, Balloon, Coronary; Calcium Channel Blocke | 1993 |
Dilated cardiomyopathy in an American cocker spaniel with taurine deficiency.
Topics: Animals; Antihypertensive Agents; Breeding; Cardiomyopathy, Dilated; Cardiotonic Agents; Digoxin; Di | 1997 |
Acute congestive heart failure associated with a limited form of systemic sclerosis and primary biliary cirrhosis.
Topics: Acute Disease; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Centromere; Coronary Circu | 2001 |
[Effect of nitroglycerin sublingually in the emergency management of "classical" pulmonary oedema (author's transl)].
Topics: Aged; Blood Pressure; Cardiac Output; Dyspnea; Female; Heart Rate; Humans; Male; Middle Aged; Nitrog | 1977 |
[Action of sustained release nitroglycerin on a pulmonary artery pressure in coronary heart disease (author's transl)].
Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Delayed-Action Preparations; Dyspnea; Human | 1977 |
Effect of sublingual nitroglycerin in emergency treatment of severe pulmonary edema.
Topics: Administration, Oral; Blood Pressure; Drug Evaluation; Dyspnea; Emergencies; Heart Rate; Humans; Myo | 1978 |
Letter: Ischemic ST segment depression and dyspnea.
Topics: Angina Pectoris; Coronary Disease; Dyspnea; Electrocardiography; Exercise Test; Heart Conduction Sys | 1975 |
[Effect of nitroglycerine in acute myocardial infarction: I: Sublingual nitroglycerine in the treatment of left-heart failure and pulmonary oedema (author's transl)].
Topics: Acute Disease; Administration, Oral; Aged; Blood Pressure; Cardiac Output; Dosage Forms; Dyspnea; He | 1975 |
Symptomatic prognosis in patients with idiopathic hypertrophic subaortic stenosis (IHSS).
Topics: Administration, Oral; Adolescent; Aged; Angina Pectoris; Blood Pressure; Cardiac Catheterization; Ca | 1973 |