Page last updated: 2024-11-01

nitroglycerin and Diseases, Peripheral Vascular

nitroglycerin has been researched along with Diseases, Peripheral Vascular in 23 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"In phenoxybenzamine-treated sections of radial artery, circulating vasoconstrictor agonists may still contribute to the induction of spasm."7.72Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators. ( Chester, MR; Conant, AR; Dihmis, WC; Oo, AY; Shackcloth, MJ; Simpson, AW, 2003)
" Forearm blood flow (FBF) and leg blood flow (LBF) responses to reactive hyperemia (RH) and sublingual administration of nitroglycerin (NTG) were measured using strain-gauge plethysmography."5.12Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease. ( Chayama, K; Goto, C; Higashi, Y; Miyazaki, M; Orihashi, K; Sanada, H; Sueda, T; Yoshizumi, M, 2007)
" Forearm blood flow (FBF) and leg blood flow (LBF) responses to reactive hyperemia and sublingual administration of nitroglycerin (NTG) were measured using strain-gauge plethysmography in 57 PAD patients and 24 control patients."3.73Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities. ( Chayama, K; Goto, C; Higashi, Y; Sanada, H; Sueda, T; Yoshizumi, M, 2005)
" A vasoregulating function of vascular endothelium was assessed with a postocclusion test with reactive hyperemia, cold and nitroglycerin tests on sites distant from the sites exposed to vibration and close to such sites."3.73[A vasoregulating function of the major vessels of the upper limbs in patients with vibration disease]. ( Gorenkov, RV; Liubchenko, PN, 2005)
"In phenoxybenzamine-treated sections of radial artery, circulating vasoconstrictor agonists may still contribute to the induction of spasm."3.72Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators. ( Chester, MR; Conant, AR; Dihmis, WC; Oo, AY; Shackcloth, MJ; Simpson, AW, 2003)
"Postoperative complications were minimal, and no patient developed hypervascularization of the glans."1.29Penile dorsal vein arterialization in managing venogenic impotence. ( Knoll, LD, 1995)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's2 (8.70)18.2507
2000's14 (60.87)29.6817
2010's4 (17.39)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Economou, FI1
Doundoulakis, I1
Kalamakidou, I1
Koliastasis, L1
Soulaidopoulos, S1
Samara, M1
Dimitriadis, K1
Papazisis, G1
Tsiachris, D1
Tsioufis, K1
Wang, X1
Derakhshandeh, R1
Liu, J1
Narayan, S1
Nabavizadeh, P1
Le, S1
Danforth, OM1
Pinnamaneni, K1
Rodriguez, HJ1
Luu, E1
Sievers, RE1
Schick, SF1
Glantz, SA1
Springer, ML1
Chung, WB1
Hamburg, NM1
Holbrook, M1
Shenouda, SM1
Dohadwala, MM1
Terry, DF1
Gokce, N1
Vita, JA1
Owens, CD1
Wake, N1
Conte, MS1
Gerhard-Herman, M1
Beckman, JA1
Shen, SC1
Ho, WJ2
Wu, SC2
Yu, KH1
Lin, HC1
Lin, YS1
Tsay, PK2
Chu, PH1
Marchetti, N1
Ciccolella, DE1
Jacobs, MR1
Crookshank, A1
Gaughan, JP1
Kashem, MA1
Bove, AA1
Criner, GJ1
Gläser, S1
Obst, A1
Opitz, CF1
Dörr, M1
Felix, SB1
Empen, K1
Völzke, H1
Ewert, R1
Schäper, C1
Koch, B1
Conant, AR1
Shackcloth, MJ1
Oo, AY1
Chester, MR1
Simpson, AW1
Dihmis, WC1
HUEBER, EF1
THALER, H1
WICK, E1
DE LA PIERRE, M1
BARBERA, G1
COSTA, P1
de Berrazueta, JR1
Sampedro, I1
Garcia-Unzueta, MT1
Llorca, J1
Bustamante, M1
Amado, JA1
Sanada, H2
Higashi, Y2
Goto, C2
Chayama, K2
Yoshizumi, M2
Sueda, T2
Heger, M1
Willfort, A1
Neunteufl, T1
Rosenhek, R1
Gabriel, H1
Wollenek, G1
Wimmer, M1
Maurer, G1
Baumgartner, H1
Kals, J1
Kampus, P1
Kals, M1
Pulges, A1
Teesalu, R1
Zilmer, M1
Liubchenko, PN1
Gorenkov, RV1
Maffei, G1
Rinaldi, M1
Rinaldi, G1
Miyazaki, M1
Orihashi, K1
Alukhanian, OA1
Martirosian, KhG1
Kurganskiĭ, OV1
Su, WW1
Cheng, ST1
Chang, SH1
Sabbá, C1
Berardi, E1
Antonica, G1
Ferraioli, G1
Buonamico, P1
Godi, L1
Brevetti, G1
Albano, O1
Knoll, LD1
Rajagopalan, S1
Shah, M1
Luciano, A1
Crystal, R1
Nabel, EG1
Kan, C1
Akimoto, S1
Abe, M1
Okada, K1
Ishikawa, O1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease[NCT02719665]30 participants (Actual)Interventional2016-03-31Completed
Arterial Imaging of Inflammation and Resolution After Endovascular Surgery[NCT03590769]Phase 19 participants (Actual)Interventional2017-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for nitroglycerin and Diseases, Peripheral Vascular

ArticleYear
Prevention of Radial Artery Spasm With Transdermal Glyceryl Trinitrate Patches: The NURSE-TTS Randomized Study.
    JACC. Cardiovascular interventions, 2023, 02-13, Volume: 16, Issue:3

    Topics: Humans; Nitroglycerin; Peripheral Vascular Diseases; Radial Artery; Spasm; Treatment Outcome; Vasodi

2023
Effect of transdermal nitroglycerin on inflammatory mediators in patients with peripheral atherosclerotic vascular disease.
    American heart journal, 2003, Volume: 146, Issue:4

    Topics: Administration, Cutaneous; Adult; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Biomarkers; C-Re

2003
Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arterial Occlusive Diseases; Biomarkers; Endothelium,

2007
Comparison between the effect of L-propionylcarnitine, L-acetylcarnitine and nitroglycerin in chronic peripheral arterial disease: a haemodynamic double blind echo-Doppler study.
    European heart journal, 1994, Volume: 15, Issue:10

    Topics: Acetylcarnitine; Blood Flow Velocity; Cardiotonic Agents; Carnitine; Child, Preschool; Cross-Over St

1994
Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve.
    Circulation, 2001, Aug-14, Volume: 104, Issue:7

    Topics: Acetylcholine; Adenoviridae; Adult; Aged; Drug Eruptions; Edema; Endothelial Growth Factors; Endothe

2001

Other Studies

18 other studies available for nitroglycerin and Diseases, Peripheral Vascular

ArticleYear
One Minute of Marijuana Secondhand Smoke Exposure Substantially Impairs Vascular Endothelial Function.
    Journal of the American Heart Association, 2016, 07-27, Volume: 5, Issue:8

    Topics: Air Pollution; Animals; Coronary Circulation; Endothelium, Vascular; Female; Marijuana Smoking; Nitr

2016
The brachial artery remodels to maintain local shear stress despite the presence of cardiovascular risk factors.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:4

    Topics: Adaptation, Physiological; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Atherosclerosis;

2009
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
    Journal of vascular surgery, 2009, Volume: 50, Issue:5

    Topics: Administration, Oral; Brachial Artery; Cohort Studies; Endothelium, Vascular; Enzyme Inhibitors; Fem

2009
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
    Journal of vascular surgery, 2009, Volume: 50, Issue:5

    Topics: Administration, Oral; Brachial Artery; Cohort Studies; Endothelium, Vascular; Enzyme Inhibitors; Fem

2009
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
    Journal of vascular surgery, 2009, Volume: 50, Issue:5

    Topics: Administration, Oral; Brachial Artery; Cohort Studies; Endothelium, Vascular; Enzyme Inhibitors; Fem

2009
In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation.
    Journal of vascular surgery, 2009, Volume: 50, Issue:5

    Topics: Administration, Oral; Brachial Artery; Cohort Studies; Endothelium, Vascular; Enzyme Inhibitors; Fem

2009
Peripheral vascular endothelial dysfunction in glaucomatocyclitic crisis: a preliminary study.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Autoantibodies; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brachial Arte

2010
Hospitalized acute exacerbation of COPD impairs flow and nitroglycerin-mediated peripheral vascular dilation.
    COPD, 2011, Volume: 8, Issue:2

    Topics: Aged; Aged, 80 and over; Brachial Artery; Disease Progression; Female; Forced Expiratory Volume; Hos

2011
Peripheral endothelial dysfunction is associated with gas exchange inefficiency in smokers.
    Respiratory research, 2011, Apr-25, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Chi-Square Distribution; Cross-Sectional Studies; D

2011
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Angiotensin II; Coronary Artery Bypass; Diltiazem; Dose-Response Re

2003
[Peripheral arterial circulatory disorders and therapy. I. Rheoangiographic registration of the effect of nitroglycerin preparations in healthy subjects].
    Zeitschrift fur Kreislaufforschung, 1956, Volume: 45, Issue:11-12

    Topics: Healthy Volunteers; Nitrites; Nitroglycerin; Peripheral Arterial Disease; Peripheral Vascular Diseas

1956
[Variations of oscillometric indices of the extremities induced by nitroglycerin in healthy subjects and in arteriopathic patients].
    Minerva cardioangiologica, 1959, Volume: 7

    Topics: Extremities; Healthy Volunteers; Humans; Nitrites; Nitroglycerin; Peripheral Vascular Diseases; Vasc

1959
Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities.
    Atherosclerosis, 2005, Volume: 178, Issue:1

    Topics: Administration, Sublingual; Aged; Ankle; Arteries; Blood Pressure; Blood Vessels; Brachial Artery; C

2005
Vascular dysfunction after coarctation repair is related to the age at surgery.
    International journal of cardiology, 2005, Mar-18, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aortic Coarctation; Blood Vessel Prosthesis Implantation; Brachial A

2005
Effects of stimulation of nitric oxide synthesis on large artery stiffness in patients with peripheral arterial disease.
    Atherosclerosis, 2006, Volume: 185, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Aorta; Arterial Occlusive Diseases; Arteries; Blood Flow Veloci

2006
[A vasoregulating function of the major vessels of the upper limbs in patients with vibration disease].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:10

    Topics: Adult; Blood Flow Velocity; Brachial Artery; Cold Temperature; Endothelium, Vascular; Hemodynamics;

2005
Resolution of peripheral tissue ischemia secondary to arterial vasospasm following treatment with a topical nitroglycerin device in two newborns: case reports.
    Journal of perinatal medicine, 2006, Volume: 34, Issue:3

    Topics: Administration, Topical; Arteries; Blood Gas Analysis; Catheterization, Peripheral; Female; Humans;

2006
[Role of sympathectomy in upper-limb critical ischaemia induced by distal lesion of arteries].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2006, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Female; Humans; Hyperemia; Ischemia; Laser-Doppler Flowmetry; Male; Middle Aged;

2006
Glaucoma is associated with peripheral vascular endothelial dysfunction.
    Ophthalmology, 2008, Volume: 115, Issue:7

    Topics: Blood Flow Velocity; Blood Pressure; Body Constitution; Brachial Artery; C-Reactive Protein; Case-Co

2008
Penile dorsal vein arterialization in managing venogenic impotence.
    Techniques in urology, 1995,Fall, Volume: 1, Issue:3

    Topics: Adult; Alprostadil; Anastomosis, Surgical; Coitus; Constriction, Pathologic; Follow-Up Studies; Huma

1995
Preliminary thermographic evaluation of new nitroglycerine tape on the peripheral circulatory disturbance in systemic sclerosis.
    Annals of the rheumatic diseases, 2002, Volume: 61, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Case-Control Studies; Drug Delivery Systems; Female; Fingers

2002