Page last updated: 2024-11-01

nitroglycerin and Disease Exacerbation

nitroglycerin has been researched along with Disease Exacerbation in 20 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"Seventeen patients with operable lung adenocarcinoma and stable angina pectoris were selected to investigate the effects of nitroglycerin on immunoreactivity for hypoxia-inducible factor 1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF), P-glycoprotein (P-gp), the production of which is regulated by HIF-1, and p53 proteins in their resected tumor by semiquantitative immunohistochemical analyses."9.12Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma. ( Asada, M; Fuji, H; Inoue, D; Kanda, A; Kaneta, T; Kondo, T; Nakayama, K; Okinaga, S; Sasaki, H; Sasaki, T; Suzuki, S; Suzuki, T; Takai, Y; Watanabe, M; Yamanda, S; Yamaya, M; Yanagihara, K; Yasuda, H; Yoshida, M; Zayasu, K, 2006)
"Addition of nitroglycerine (NTG) to transcatheter arterial embolization/transarterial chemoembolization (TAE/TACE) has been shown to increase deposition of Lipiodol emulsion in hepatocellular carcinoma (HCC) tumors."7.88Nitroglycerine use in transcatheter arterial (chemo) embolization in patients with hepatocellular carcinoma: Five-year retrospective study. ( Chuang, MT; Lin, CY; Liu, YS; Ou, MC; Tsai, YS; Wang, CK, 2018)
"Seventeen patients with operable lung adenocarcinoma and stable angina pectoris were selected to investigate the effects of nitroglycerin on immunoreactivity for hypoxia-inducible factor 1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF), P-glycoprotein (P-gp), the production of which is regulated by HIF-1, and p53 proteins in their resected tumor by semiquantitative immunohistochemical analyses."5.12Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma. ( Asada, M; Fuji, H; Inoue, D; Kanda, A; Kaneta, T; Kondo, T; Nakayama, K; Okinaga, S; Sasaki, H; Sasaki, T; Suzuki, S; Suzuki, T; Takai, Y; Watanabe, M; Yamanda, S; Yamaya, M; Yanagihara, K; Yasuda, H; Yoshida, M; Zayasu, K, 2006)
"Addition of nitroglycerine (NTG) to transcatheter arterial embolization/transarterial chemoembolization (TAE/TACE) has been shown to increase deposition of Lipiodol emulsion in hepatocellular carcinoma (HCC) tumors."3.88Nitroglycerine use in transcatheter arterial (chemo) embolization in patients with hepatocellular carcinoma: Five-year retrospective study. ( Chuang, MT; Lin, CY; Liu, YS; Ou, MC; Tsai, YS; Wang, CK, 2018)
" We used glyceryl trinitrate (nitroglycerin) to trigger premonitory symptoms and migraine headache in patients with episodic migraine without aura who habitually experienced premonitory symptoms during spontaneous attacks."3.80Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks. ( Goadsby, PJ; Maniyar, FH; Monteith, T; Schankin, C; Sprenger, T, 2014)
"Coronary vasodilator function and atherosclerotic plaque progression have both been shown to be associated with adverse cardiovascular events."2.87Evaluation of human coronary vasodilator function predicts future coronary atheroma progression. ( Baillie, TJ; Beltrame, JF; Delacroix, S; Honda, S; Howell, S; Kim, S; Montarello, N; Nicholls, SJ; Psaltis, PJ; Shishikura, D; Sidharta, SL; Worthley, MI; Worthley, SG, 2018)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's9 (45.00)29.6817
2010's8 (40.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Butala, NM1
Tamez, H1
Secemsky, EA1
Grantham, JA1
Spertus, JA1
Cohen, DJ1
Jones, P1
Salisbury, AC1
Arnold, SV1
Harrell, F1
Lombardi, W1
Karmpaliotis, D1
Moses, J1
Sapontis, J1
Yeh, RW1
Sidharta, SL1
Baillie, TJ1
Howell, S1
Nicholls, SJ1
Montarello, N1
Honda, S1
Shishikura, D1
Delacroix, S1
Kim, S1
Beltrame, JF1
Psaltis, PJ1
Worthley, SG1
Worthley, MI1
Liu, YS1
Lin, CY1
Chuang, MT1
Tsai, YS1
Wang, CK1
Ou, MC1
Abad, N1
Rosenberg, JT1
Hike, DC1
Harrington, MG1
Grant, SC1
Figueras, J1
Domingo, E1
Ferreira, I1
Lidón, RM1
Bellera, N1
Garcia-Dorado, D1
Maniyar, FH1
Sprenger, T1
Monteith, T1
Schankin, C1
Goadsby, PJ1
Hohl, M1
Linz, D1
Fries, P1
Müller, A1
Stroeder, J1
Urban, D1
Speer, T1
Geisel, J1
Hummel, B1
Laufs, U1
Schirmer, SH1
Böhm, M1
Mahfoud, F1
Marchetti, N1
Ciccolella, DE1
Jacobs, MR1
Crookshank, A1
Gaughan, JP1
Kashem, MA1
Bove, AA1
Criner, GJ1
Sheta, MA1
Paladugu, M1
Mendelson, J1
Holland, NR1
Shlipak, MG1
Massie, BM1
Cake, MA1
Read, RA1
Appleyard, RC1
Hwa, SY1
Ghosh, P1
Bisognano, JD1
Lindenfeld, J1
Hammond, E1
Zisman, LS1
Shangina, OA1
Kostin, VI1
Koturga, LI1
Larsen, AI1
Dickstein, K1
Ahmadi, NS1
Aarsland, T1
Kvaløy, JT1
Hall, C1
Yasuda, H1
Nakayama, K1
Watanabe, M1
Suzuki, S1
Fuji, H1
Okinaga, S1
Kanda, A1
Zayasu, K1
Sasaki, T1
Asada, M1
Suzuki, T1
Yoshida, M1
Yamanda, S1
Inoue, D1
Kaneta, T1
Kondo, T1
Takai, Y1
Sasaki, H1
Yanagihara, K1
Yamaya, M1
Yee, J1
Bhabra, MS1
Hopkinson, DN1
Shaw, TE1
Hooper, TL1
Hernandez, A1
Barberi, L1
Ballerio, R1
Testini, A1
Ferioli, R1
Bolla, M1
Natali, M1
Folco, G1
Catapano, AL1
Ogawa, H1
Soejima, H1
Takazoe, K1
Miyamoto, S1
Kajiwara, I1
Shimomura, H1
Sakamoto, T1
Yoshimura, M1
Kugiyama, K1
Kimura, M1
Yasue, H1
Ikeda, N1
Yasu, T1
Yamada, S1
Ino, T1
Saito, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Biomarker Identification to Predict the Evolution of Migraine From an Episodic to a Chronic Condition[NCT04696510]15 participants (Actual)Observational2018-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for nitroglycerin and Disease Exacerbation

ArticleYear
Evaluation of human coronary vasodilator function predicts future coronary atheroma progression.
    Heart (British Cardiac Society), 2018, Volume: 104, Issue:17

    Topics: Aged; Albuterol; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Disease Progressio

2018
The effect of altering haemodynamics on the plasma concentrations of natriuretic peptides in heart failure.
    European journal of heart failure, 2006, Volume: 8, Issue:6

    Topics: Cardiac Output, Low; Cross-Over Studies; Disease Progression; Female; Humans; Male; Middle Aged; Nat

2006
Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding

2006

Other Studies

17 other studies available for nitroglycerin and Disease Exacerbation

ArticleYear
Predicting Residual Angina After Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the OPEN-CTO Registry.
    Journal of the American Heart Association, 2022, 05-17, Volume: 11, Issue:10

    Topics: Angina Pectoris; Chronic Disease; Coronary Angiography; Coronary Occlusion; Disease Progression; Hum

2022
Nitroglycerine use in transcatheter arterial (chemo) embolization in patients with hepatocellular carcinoma: Five-year retrospective study.
    Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined

2018
Dynamic sodium imaging at ultra-high field reveals progression in a preclinical migraine model.
    Pain, 2018, Volume: 159, Issue:10

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Disease Progression; Dose-Response Relationsh

2018
Typical angina without significant coronary stenosis: comparison of clinical profile, circadian presentation, and long-term follow-up between patients with and patients without vasospastic angina.
    Coronary artery disease, 2013, Volume: 24, Issue:5

    Topics: Adult; Chi-Square Distribution; Circadian Rhythm; Coronary Angiography; Coronary Vasospasm; Diabetes

2013
Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 1

    Topics: Adult; Brain; Cerebrovascular Circulation; Data Interpretation, Statistical; Disease Progression; Fe

2014
Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats.
    Journal of translational medicine, 2016, 06-08, Volume: 14, Issue:1

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Carbachol; Denervat

2016
Hospitalized acute exacerbation of COPD impairs flow and nitroglycerin-mediated peripheral vascular dilation.
    COPD, 2011, Volume: 8, Issue:2

    Topics: Aged; Aged, 80 and over; Brachial Artery; Disease Progression; Female; Forced Expiratory Volume; Hos

2011
When should nitroglycerine be avoided in hypertensive encephalopathy?
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:5

    Topics: Contraindications; Disease Progression; Follow-Up Studies; Humans; Hypertensive Encephalopathy; Infu

2011
The clinical challenge of cardiorenal syndrome.
    Circulation, 2004, Sep-21, Volume: 110, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Case Management; Cohort Studies; Creatinine; Disease Progr

2004
The nitric oxide donor glyceryl trinitrate increases subchondral bone sclerosis and cartilage degeneration following ovine meniscectomy.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:12

    Topics: Animals; Biomechanical Phenomena; Bone and Bones; Cartilage, Articular; Disease Progression; Female;

2004
Coronary artery vasospasm causing acute myocardial infarction in a heart transplant recipient.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:3

    Topics: Acute Disease; Coronary Angiography; Coronary Vasospasm; Disease Progression; Graft Rejection; Heart

2005
[Effects of therapy with various groups of antianginal agents on life quality of the elderly with coronary heart disease and comorbid depression].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:7

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Atenolol; Calcium Channel Blockers; Depression; Dise

2005
Chronic kidney disease--a disease domain complex.
    Geriatrics, 2008, Volume: 63, Issue:3

    Topics: Aged; Alendronate; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Asp

2008
Attenuation of lung graft reperfusion injury by a nitric oxide donor.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 113, Issue:2

    Topics: Animals; Cardioplegic Solutions; Disease Models, Animal; Disease Progression; Hemodynamics; Hydralaz

1997
Delapril slows the progression of atherosclerosis and maintains endothelial function in cholesterol-fed rabbits.
    Atherosclerosis, 1998, Volume: 137, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Aorta, Thoracic; Arterioscleros

1998
Increased autoantibodies against oxidized low-density lipoprotein in coronary circulation in patients with coronary spastic angina.
    Angiology, 2001, Volume: 52, Issue:3

    Topics: Acetylcholine; Administration, Sublingual; Adult; Aged; Angina Pectoris, Variant; Autoantibodies; Bi

2001
Echocardiographical demonstration of a progressively expanding left ventricular aneurysm preceded by endomyocardial tearing.
    Japanese circulation journal, 2001, Volume: 65, Issue:4

    Topics: Aged; Aneurysm, False; Antihypertensive Agents; Combined Modality Therapy; Coronary Disease; Disease

2001