Page last updated: 2024-11-01

nitroglycerin and Diabetic Retinopathy

nitroglycerin has been researched along with Diabetic Retinopathy in 3 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"Twenty patients with type 1 diabetes mellitus featuring no or mild nonproliferative diabetic retinopathy and 20 healthy, age-matched subjects were included in this study."2.74Reduced retinal vessel response to flicker stimulation but not to exogenous nitric oxide in type 1 diabetes. ( Garhofer, G; Karl, K; Pemp, B; Resch, H; Schmetterer, L; Weigert, G; Wolzt, M, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pemp, B1
Garhofer, G1
Weigert, G1
Karl, K1
Resch, H1
Wolzt, M1
Schmetterer, L1
Frauchiger, B1
Nussbaumer, P1
Hugentobler, M1
Staub, D1
Dogra, G1
Rich, L1
Stanton, K1
Watts, GF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers[NCT00432029]80 participants (Actual)Interventional2006-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nitroglycerin and Diabetic Retinopathy

ArticleYear
Reduced retinal vessel response to flicker stimulation but not to exogenous nitric oxide in type 1 diabetes.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:9

    Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glyca

2009

Other Studies

2 other studies available for nitroglycerin and Diabetic Retinopathy

ArticleYear
Duplex sonographic registration of age and diabetes-related loss of renal vasodilatory response to nitroglycerine.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arterioles; Diabetes Mellitus, Type 1; Diabetes Mellitus, Typ

2000
Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria.
    Diabetologia, 2001, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood

2001