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nitroglycerin and Diabetic Neuropathies

nitroglycerin has been researched along with Diabetic Neuropathies in 8 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"Fifty patients with painful diabetic neuropathy (type 2) were screened consecutively, out of which two were excluded (1 with HbA(1)c>11 and one withdrew his consent)."2.73Glyceryl trinitrate spray in the management of painful diabetic neuropathy: a randomized double blind placebo controlled cross-over study. ( Agrawal, RP; Beniwal, R; Choudhary, R; Kaswan, K; Kochar, DK; Sharma, P; Sharma, S, 2007)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agrawal, RP2
Goswami, J1
Jain, S1
Kochar, DK2
Araiza-Saldaña, CI1
Rocha-González, HI1
Ambriz-Tututi, M1
Castañeda-Corral, G1
Caram-Salas, NL1
Hong, E1
Granados-Soto, V1
Rayman, G1
Baker, NR1
Krishnan, ST1
Higa, M1
Takasu, N1
Tamanaha, T1
Nakamura, K1
Shimabukuro, M1
Sasara, T1
Tawata, M1
Choudhary, R1
Sharma, P1
Sharma, S1
Beniwal, R1
Kaswan, K1
Robinson, D1
Yesavage, J1
Tinklenberg, J1
Dogra, G1
Rich, L1
Stanton, K1
Watts, GF1
Low, PA1
Walsh, JC1
Huang, CY1
McLeod, JG1

Trials

3 trials available for nitroglycerin and Diabetic Neuropathies

ArticleYear
Management of diabetic neuropathy by sodium valproate and glyceryl trinitrate spray: a prospective double-blind randomized placebo-controlled study.
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:3

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Diabetes Mellitus, Type 2; Diabetic Neuropathies;

2009
Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy.
    Diabetes care, 2003, Volume: 26, Issue:9

    Topics: Administration, Cutaneous; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathi

2003
Glyceryl trinitrate spray in the management of painful diabetic neuropathy: a randomized double blind placebo controlled cross-over study.
    Diabetes research and clinical practice, 2007, Volume: 77, Issue:2

    Topics: Administration, Topical; Blood Glucose; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Meth

2007

Other Studies

5 other studies available for nitroglycerin and Diabetic Neuropathies

ArticleYear
Sildenafil and glyceryl trinitrate reduce tactile allodynia in streptozotocin-injected rats.
    European journal of pharmacology, 2010, Apr-10, Volume: 631, Issue:1-3

    Topics: Administration, Cutaneous; Analgesics; Animals; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabet

2010
Nitroglycerin spray rapidly improves pain in a patient with chronic painful diabetic neuropathy.
    Diabetic medicine : a journal of the British Diabetic Association, 2004, Volume: 21, Issue:9

    Topics: Administration, Topical; Adult; Chronic Disease; Diabetic Neuropathies; Humans; Male; Nitric Oxide D

2004
Diabetic neuropathy and possible treatment.
    Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:5

    Topics: Aged; Aged, 80 and over; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Nitroglycerin; Oi

1994
Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria.
    Diabetologia, 2001, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood

2001
The sympathetic nervous system in diabetic neuropathy. A clinical and pathological study.
    Brain : a journal of neurology, 1975, Volume: 98, Issue:3

    Topics: Adult; Blood Pressure; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Nitroglycerin; Phen

1975