Page last updated: 2024-11-01

nitroglycerin and Diabetic Foot

nitroglycerin has been researched along with Diabetic Foot in 2 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Diabetic Foot: Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.

Research Excerpts

ExcerptRelevanceReference
"Nitroglycerin (NTG) is an organic nitrate rapidly denitrated by enzymes to release free radical nitric oxide and shows improved wound healing and tissue protection from oxidative damage."1.42Preliminary investigation of topical nitroglycerin formulations containing natural wound healing agent in diabetes-induced foot ulcer. ( Avachat, AM; Bhosale, SS; Hotkar, MS; Oswal, YM, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hotkar, MS1
Avachat, AM1
Bhosale, SS1
Oswal, YM1
Mikaili, P1
Moloudizargari, M1
Aghajanshakeri, S1

Other Studies

2 other studies available for nitroglycerin and Diabetic Foot

ArticleYear
Preliminary investigation of topical nitroglycerin formulations containing natural wound healing agent in diabetes-induced foot ulcer.
    International wound journal, 2015, Volume: 12, Issue:2

    Topics: Administration, Topical; Animals; Diabetic Foot; Disease Models, Animal; Female; Gels; Male; Nitrogl

2015
Treatment with topical nitroglycerine may promote the healing process of diabetic foot ulcers.
    Medical hypotheses, 2014, Volume: 83, Issue:2

    Topics: Administration, Topical; Diabetic Foot; Humans; Models, Biological; Nitric Oxide; Nitroglycerin; Reg

2014