Page last updated: 2024-11-01

nitroglycerin and Diabetes Mellitus

nitroglycerin has been researched along with Diabetes Mellitus in 21 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"Endothelial function by flow-mediated (FMD) and nitroglycerin-mediated vasodilations (NMD) was scarcely investigated in resistant hypertension."7.81Nitroglycerin-mediated, but not flow-mediated vasodilation, is associated with blunted nocturnal blood pressure fall in patients with resistant hypertension. ( Cardoso, CR; Fontes-Guerra, PC; Muxfeldt, ES; Salles, GF, 2015)
"Endothelial function by flow-mediated (FMD) and nitroglycerin-mediated vasodilations (NMD) was scarcely investigated in resistant hypertension."3.81Nitroglycerin-mediated, but not flow-mediated vasodilation, is associated with blunted nocturnal blood pressure fall in patients with resistant hypertension. ( Cardoso, CR; Fontes-Guerra, PC; Muxfeldt, ES; Salles, GF, 2015)
"Patients with DM and ESRD had impaired coronary vasodilation to NTG compared to age-matched controls (17."1.35Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease. ( Engvall, J; McConnell, MV; Meyer, C; Nguyen, PK; Yang, P, 2008)
"Thus, type II diabetes mellitus impairs nitric oxide synthase-dependent responses of cerebral arterioles."1.32Impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type II diabetic rats. ( Mayhan, WG; Schwaninger, RM; Sun, H, 2003)
"Based on our results, as coronary atherosclerosis becomes more severe, the adjusted brachial artery FMD becomes more severely impaired."1.30The correlation between coronary stenosis index and flow-mediated dilation of the brachial artery. ( Arai, Y; Hirase, H; Kaku, B; Mizuno, S; Moriuchi, I; Murakami, T; Nagata, M; Nio, Y; Ohnaka, M; Ohsato, K; Takahashi, Y, 1998)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's2 (9.52)18.2507
2000's11 (52.38)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, QQ1
Cheng, N1
Yi, WB1
Peng, SM1
Zou, XQ1
Dalen, JE1
Figueras, J1
Domingo, E1
Ferreira, I1
Lidón, RM1
Bellera, N1
Garcia-Dorado, D1
Wong, CK1
Chen, Y1
Ho, LM1
Zhen, Z1
Siu, CW1
Tse, HF1
Yiu, KH1
Fontes-Guerra, PC1
Cardoso, CR1
Muxfeldt, ES1
Salles, GF1
Nguyen, PK1
Meyer, C1
Engvall, J1
Yang, P1
McConnell, MV1
Rus, R1
Buturović-Ponikvar, J1
SCHWARTZ, W1
MILLER, HI1
ISSEKUTZ, B1
RODAHL, K1
PAUL, P1
Schwaninger, RM1
Sun, H1
Mayhan, WG1
Oshima, T1
Yano, Y1
Nakajima, H1
Oishi, T1
Kambe, M1
Toyama, C1
Yoshioka, T1
Ozono, R1
Karaaslan, P1
Dönmez, A1
Arslan, G1
Ghiadoni, L1
Penno, G1
Giannarelli, C1
Plantinga, Y1
Bernardini, M1
Pucci, L1
Miccoli, R1
Taddei, S1
Salvetti, A1
Del Prato, S1
Anfossi, G1
Mularoni, EM1
Burzacca, S1
Ponziani, MC1
Massucco, P1
Mattiello, L1
Cavalot, F1
Trovati, M1
Kaku, B1
Mizuno, S1
Ohsato, K1
Murakami, T1
Moriuchi, I1
Arai, Y1
Nio, Y1
Hirase, H1
Nagata, M1
Takahashi, Y1
Ohnaka, M1
Matata, BM1
Galiñanes, M1
Mussi, C1
Tolve, I1
Foroni, M1
Valli, A1
Ascari, S1
Salvioli, G1
Whalley, GA1
Bagg, W1
Doughty, RN1
Gamble, G1
Braatvedt, G1
Sharpe, N1
Hashimoto, M1
Akita, H1
Stein, JH1
Carlsson, CM1
Kontturi, M1
Sotaniemi, E1
Ahlqvist, J1

Reviews

2 reviews available for nitroglycerin and Diabetes Mellitus

ArticleYear
Synthesis, nitric oxide release, and α-glucosidase inhibition of nitric oxide donating apigenin and chrysin derivatives.
    Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5

    Topics: alpha-Glucosidases; Apigenin; Diabetes Complications; Diabetes Mellitus; Flavonoids; Humans; Hypogly

2014
[Establishment of a clinical method for evaluating flow-mediated vasodilation(FMD) in brachial artery].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:2

    Topics: Arteriosclerosis; Biomechanical Phenomena; Brachial Artery; Coronary Disease; Diabetes Mellitus; Dia

2004

Trials

2 trials available for nitroglycerin and Diabetes Mellitus

ArticleYear
Cardiopulmonary bypass exacerbates oxidative stress but does not increase proinflammatory cytokine release in patients with diabetes compared with patients without diabetes: regulatory effects of exogenous nitric oxide.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 120, Issue:1

    Topics: Aged; Cardiopulmonary Bypass; Complement C3; Cytokines; Diabetes Mellitus; E-Selectin; Female; Human

2000
Specificity and total positive rate of head-up tilt testing potentiated with sublingual nitroglycerin in older patients with unexplained syncope.
    Aging (Milan, Italy), 2001, Volume: 13, Issue:2

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Blood Pressure; Diabetes Mellitus; Female; Hear

2001

Other Studies

17 other studies available for nitroglycerin and Diabetes Mellitus

ArticleYear
A Christmas Story.
    JAMA cardiology, 2019, 06-01, Volume: 4, Issue:6

    Topics: Cardiac Catheterization; Diabetes Mellitus; Diuretics; Electrocardiography; Female; Furosemide; Holi

2019
Typical angina without significant coronary stenosis: comparison of clinical profile, circadian presentation, and long-term follow-up between patients with and patients without vasospastic angina.
    Coronary artery disease, 2013, Volume: 24, Issue:5

    Topics: Adult; Chi-Square Distribution; Circadian Rhythm; Coronary Angiography; Coronary Vasospasm; Diabetes

2013
The effects of hyperuricaemia on flow-mediated and nitroglycerin-mediated dilatation in high-risk patients.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; D

2014
Nitroglycerin-mediated, but not flow-mediated vasodilation, is associated with blunted nocturnal blood pressure fall in patients with resistant hypertension.
    Journal of hypertension, 2015, Volume: 33, Issue:8

    Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Cross-Sectional Studie

2015
Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2008, May-30, Volume: 10

    Topics: Blood Pressure; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus; Female; Heart Rate; Hu

2008
Intima media thickness and endothelial function in chronic hemodialysis patients.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2009, Volume: 13, Issue:4

    Topics: Adult; Age Factors; Brachial Artery; Cardiovascular Diseases; Carotid Arteries; Diabetes Mellitus; E

2009
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates;

1964
EFFECT OF LACTIC ACID ON PLASMA FREE FATTY ACIDS IN PANCREATECTOMIZED DOGS.
    The American journal of physiology, 1964, Volume: 207

    Topics: Acetylcholine; Animals; Blood; Diabetes Mellitus; Dogs; Fatty Acids; Fatty Acids, Nonesterified; Glu

1964
Impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type II diabetic rats.
    Life sciences, 2003, Nov-14, Volume: 73, Issue:26

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arterioles; Blotting, Western; Cerebrovascular Circul

2003
Severe hypoxaemia following intravenous nitroglycerine administration in an obese patient: case report.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:12

    Topics: Adult; Anesthesia, General; Diabetes Mellitus; Humans; Hypertension; Hypoxia; Infusions, Intravenous

2005
Metabolic syndrome and vascular alterations in normotensive subjects at risk of diabetes mellitus.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Adult; Arteries; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Artery, Common; Cross

2008
Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM.
    Diabetes care, 1998, Volume: 21, Issue:1

    Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Pressure;

1998
The correlation between coronary stenosis index and flow-mediated dilation of the brachial artery.
    Japanese circulation journal, 1998, Volume: 62, Issue:6

    Topics: Adult; Aged; Angina, Unstable; Brachial Artery; Coronary Angiography; Coronary Artery Disease; Coron

1998
Pseudonormal diastolic filling unmasked with glyceryl trinitrate in patients with type 2 diabetes with poor metabolic control.
    Diabetes care, 2001, Volume: 24, Issue:7

    Topics: Biomarkers; Blood Glucose; Body Surface Area; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diastole

2001
Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
    Circulation, 2002, Jan-29, Volume: 105, Issue:4

    Topics: Aged; Arteriosclerosis; Diabetes Mellitus; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA

2002
Cerivastatin and endothelial function in elderly patients with diabetes mellitus.
    Circulation, 2002, Jan-29, Volume: 105, Issue:4

    Topics: Aged; Brachial Artery; Diabetes Mellitus; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA R

2002
Liver damage and estrogen therapy of prostatic cancer. Case report.
    Scandinavian journal of urology and nephrology, 1972, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Aged; Blood Glucose; Carbutamide; Diabetes Mellitus; Diethylstilbestrol; Digoxin; Dr

1972