nitroglycerin has been researched along with Crohn Disease in 2 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with a Crohn's disease activity index of > or = 150 and < 450 were randomized to receive 12 weeks of either glyceryl trinitrate (initially 6 mg twice daily, increasing to 9 mg twice daily after 6 weeks) or an identical placebo." | 2.70 | Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial. ( Ch'Ng, CL; Evans, BK; Green, JT; Hawkes, ND; Hawthorne, AB; Kingham, JG; Mayberry, JF; Rhodes, J; Rhodes, P; Richardson, C; Swift, GL; Thomas, GA; Williams, J, 2001) |
| "Functional atherosclerosis is present in inflammatory bowel disease before early structural changes occur in vasculature." | 1.38 | Evaluation of early atherosclerosis in patients with inflammatory bowel disease. ( Akarsu, M; Akpinar, H; Cullu, N; Demir, S; Goktay, Y; Kayahan, H; Sari, I; Unsal, B; Yuksel, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kayahan, H | 1 |
| Sari, I | 1 |
| Cullu, N | 1 |
| Yuksel, F | 1 |
| Demir, S | 1 |
| Akarsu, M | 1 |
| Goktay, Y | 1 |
| Unsal, B | 1 |
| Akpinar, H | 1 |
| Hawkes, ND | 1 |
| Richardson, C | 1 |
| Ch'Ng, CL | 1 |
| Green, JT | 1 |
| Evans, BK | 1 |
| Williams, J | 1 |
| Rhodes, P | 1 |
| Rhodes, J | 1 |
| Swift, GL | 1 |
| Thomas, GA | 1 |
| Hawthorne, AB | 1 |
| Kingham, JG | 1 |
| Mayberry, JF | 1 |
1 trial available for nitroglycerin and Crohn Disease
| Article | Year |
|---|---|
Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adult; Crohn Disease; Dizziness; Double-Blind Method; Exanthema; Female; Flush | 2001 |
1 other study available for nitroglycerin and Crohn Disease
| Article | Year |
|---|---|
Evaluation of early atherosclerosis in patients with inflammatory bowel disease.
Topics: Adult; Atherosclerosis; Brachial Artery; Carotid Intima-Media Thickness; Case-Control Studies; Colit | 2012 |