Page last updated: 2024-11-01

nitroglycerin and Coronary Restenosis

nitroglycerin has been researched along with Coronary Restenosis in 12 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.

Research Excerpts

ExcerptRelevanceReference
"ST-segment elevation is frequently induced by dobutamine in patients with a recent myocardial infarction and may represent dyskinesia of the infarcted region or myocardial viability and ischaemia."7.72Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery. ( Canosi, U; Klersy, C; Lanzarini, L; Previtali, M; Scelsi, L; Sebastiani, R, 2003)
"ST-segment elevation is frequently induced by dobutamine in patients with a recent myocardial infarction and may represent dyskinesia of the infarcted region or myocardial viability and ischaemia."3.72Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery. ( Canosi, U; Klersy, C; Lanzarini, L; Previtali, M; Scelsi, L; Sebastiani, R, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sabaté, M1
Alfonso, F1
Cequier, A1
Romaní, S1
Bordes, P1
Serra, A1
Iñiguez, A1
Salinas, P1
García Del Blanco, B1
Goicolea, J1
Hernández-Antolín, R1
Cuesta, J1
Gómez-Hospital, JA1
Ortega-Paz, L1
Gomez-Lara, J1
Brugaletta, S1
Roa-Garrido, J1
Gomez-Menchero, AE1
El Amrawy, AM1
Cardenal-Piris, R1
Camacho-Freire, S1
Diaz-Fernandez, JF1
Farhan, S1
Hemetsberger, R1
Matiasek, J1
Strehblow, C1
Pavo, N1
Khorsand, A1
Petneházy, O1
Petrási, Z1
Kaider, A1
Glogar, D1
Huber, K1
Gyöngyösi, M1
Akcakoyun, M1
Kargin, R1
Tanalp, AC1
Pala, S1
Ozveren, O1
Akcay, M1
Barutcu, I1
Kirma, C1
Sharma, AK1
Ajani, AE1
Garg, N1
GebreEyesus, A1
Varghese, J1
Pinnow, E1
Waksman, R1
Pichard, AD1
Lindsay, J1
Lanzarini, L1
Scelsi, L1
Canosi, U1
Klersy, C1
Sebastiani, R1
Previtali, M1
Togni, M2
Windecker, S2
Wenaweser, P2
Tueller, D1
Kaisaier, A1
Maier, W1
Meier, B2
Hess, OM2
Tepliakov, AT1
Rybal'chenko, EV1
Krylov, AL1
Stepacheva, TA1
Vesnina, ZhV1
D'iakova, ML1
Hofma, SH1
van der Giessen, WJ1
van Dalen, BM1
Lemos, PA1
McFadden, EP1
Sianos, G1
Ligthart, JM1
van Essen, D1
de Feyter, PJ1
Serruys, PW1
Thanyasiri, P1
Kathir, K1
Celermajer, DS1
Adams, MR1
Räber, L1
Cocchia, R1
Cook, S1
Wei, W1
Floten, HS1
He, GW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MAGnesium-based Bioresorbable Scaffold and Vasomotor Function in Patients With Acute ST Segment Elevation Myocardial Infarction[NCT03234348]Phase 3151 participants (Actual)Interventional2017-07-01Completed
Phase 4 Study of Randomized Comparison Among Oral Rapamycin Plus Bare Metal Stents Versus Drug Eluting Stents in de Novo Coronary Lesions.[NCT00552669]Phase 4200 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Differences in Costs Between Two Revascularization Strategies for de Novo Coronary Lesions.

Overall costs expressed in US dollars at 18 months of follow up between Oral Sirolimus Plus BMS vs DES implantation in denovo coronary lesions. (NCT00552669)
Timeframe: Follow up will be conducted by the coordinating Center at 18 months of follow up

InterventionUS dollars (Mean)
Oral Sirolimus + Bare Metal Stent5483
Drug Eluting Stents7658.2

Target Vessel Revascularization (TVR)

Efficacy end point was TVR as revasacularization of the treated vessel. (NCT00552669)
Timeframe: 18 months

Interventionvessels (Number)
Oral Sirolimus + Bare Metal Stent14
Drug Eluting Stents15

Major Adverse Cardiovascular Events (MACCE)

Death from any cause, myocardial infarction and stroke. Safety was analyzed as MACCE (major adverse cardiovascular events) including death, MI and stroke. (NCT00552669)
Timeframe: 18 Months

,
Interventionparticipants (Number)
MACCEDeathAcute Myocardial InfarctionStroke
Drug Eluting Stents15791
Oral Sirolimus + Bare Metal Stent9360

Trials

2 trials available for nitroglycerin and Coronary Restenosis

ArticleYear
Magnesium-Based Resorbable Scaffold Versus Permanent Metallic Sirolimus-Eluting Stent in Patients With ST-Segment Elevation Myocardial Infarction: The MAGSTEMI Randomized Clinical Trial.
    Circulation, 2019, 12-03, Volume: 140, Issue:23

    Topics: Absorbable Implants; Acetylcholine; Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coro

2019
Interaction between vasodilators and vasopressin in internal mammary artery and clinical significance.
    The Annals of thoracic surgery, 2002, Volume: 73, Issue:2

    Topics: Arginine Vasopressin; Coronary Artery Bypass; Coronary Restenosis; Culture Techniques; Diltiazem; Do

2002

Other Studies

10 other studies available for nitroglycerin and Coronary Restenosis

ArticleYear
Optical Coherence Tomography Image of Coronary Spasm in a Bioresorbable Vascular Scaffold.
    The Canadian journal of cardiology, 2018, Volume: 34, Issue:3

    Topics: Absorbable Implants; Acute Coronary Syndrome; Coronary Angiography; Coronary Restenosis; Coronary St

2018
Implantation of paclitaxel-eluting stent impairs the vascular compliance of arteries in porcine coronary stenting model.
    Atherosclerosis, 2009, Volume: 202, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coronary Restenosis; Coronary Stenosis; Coronary Vessels

2009
Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events and restenosis in patients undergoing coronary stent implantation: a prospective study.
    Coronary artery disease, 2008, Volume: 19, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases;

2008
Percutaneous interventions in radial artery grafts: clinical and angiographic outcomes.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2003, Volume: 59, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enz

2003
Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery.
    Acta cardiologica, 2003, Volume: 58, Issue:6

    Topics: Adrenergic beta-Agonists; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Co

2003
Deleterious effect of coronary brachytherapy on vasomotor response to exercise.
    Circulation, 2004, Jul-13, Volume: 110, Issue:2

    Topics: Aged; Angioplasty, Balloon; Brachytherapy; Coronary Angiography; Coronary Restenosis; Coronary Steno

2004
[An experience of the use of stenting for recurrence of myocardial ischemia after coronary artery bypass grafting].
    Kardiologiia, 2005, Volume: 45, Issue:1

    Topics: Coronary Angiography; Coronary Artery Bypass; Coronary Restenosis; Exercise Test; Female; Humans; Hy

2005
Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation.
    European heart journal, 2006, Volume: 27, Issue:2

    Topics: Aged; Coronary Angiography; Coronary Restenosis; Coronary Vasospasm; Diabetes Mellitus, Type 2; Diab

2006
Endothelial dysfunction and restenosis following percutaneous coronary intervention.
    International journal of cardiology, 2007, Jul-31, Volume: 119, Issue:3

    Topics: Acetylcholine; Aged; Angioplasty, Balloon, Coronary; Case-Control Studies; Coronary Angiography; Cor

2007
Local vascular dysfunction after coronary paclitaxel-eluting stent implantation.
    International journal of cardiology, 2007, Aug-21, Volume: 120, Issue:2

    Topics: Administration, Sublingual; Antineoplastic Agents, Phytogenic; Blood Vessel Prosthesis Implantation;

2007