nitroglycerin has been researched along with Common Migraine in 13 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this double-blind, randomized and placebo-controlled, crossover study 15 migraineurs with migraine without aura were pre-treated with 150 mg of prednisolone or placebo followed by a 20-min infusion of GTN (0." | 5.14 | Prednisolone reduces nitric oxide-induced migraine. ( Daugaard, D; Iversen, HK; Lassen, LH; Olesen, J; Tfelt-Hansen, P, 2009) |
| " We investigated flow-mediated vasodilatation (FMD) and nitroglycerin-mediated vasodilatation (NMD) of the brachial artery by means of a key molecular mediator, NO, in patients with migraine without aura in the interictal period whether the abnormality is found." | 3.88 | Increased nitroglycerin-mediated vasodilation in migraineurs without aura in the interictal period. ( Fujioka, A; Fujioka, K; Nakayama, T; Oishi, M, 2018) |
| " We used glyceryl trinitrate (nitroglycerin) to trigger premonitory symptoms and migraine headache in patients with episodic migraine without aura who habitually experienced premonitory symptoms during spontaneous attacks." | 3.80 | Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks. ( Goadsby, PJ; Maniyar, FH; Monteith, T; Schankin, C; Sprenger, T, 2014) |
| "Sumatriptan nasal spray was administered 120 min after the onset of the attack." | 2.71 | Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack. ( Bagdy, G; Jakab, B; Juhasz, G; Nemeth, J; Szolcsanyi, J; Zsombok, T, 2005) |
| "In contrast to patients with migraine with aura (MA) and migraine without aura (MO), most patients with familial hemiplegic migraine (FHM) do not report migraine-like attacks after pharmacologic provocation with glyceryl trinitrate (GTN), a donor of nitric oxide." | 1.36 | Coexisting typical migraine in familial hemiplegic migraine. ( Ashina, M; Hansen, JM; Olesen, J; Thomsen, LL, 2010) |
| "We assessed a patient with cluster headache and migraine by positron emission tomography during an active cluster headache after he had taken 1." | 1.31 | Brainstem activation specific to migraine headache. ( Bahra, A; Buchel, C; Frackowiak, RS; Goadsby, PJ; Matharu, MS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujioka, K | 1 |
| Oishi, M | 1 |
| Fujioka, A | 1 |
| Nakayama, T | 1 |
| Maniyar, FH | 1 |
| Sprenger, T | 1 |
| Monteith, T | 1 |
| Schankin, C | 1 |
| Goadsby, PJ | 2 |
| Daugaard, D | 3 |
| Thomsen, LL | 4 |
| Iversen, HK | 3 |
| Olesen, J | 5 |
| Tfelt-Hansen, P | 1 |
| Lassen, LH | 1 |
| Hansen, JM | 1 |
| Ashina, M | 1 |
| Perrotta, A | 1 |
| Serrao, M | 1 |
| Tassorelli, C | 1 |
| Arce-Leal, N | 1 |
| Guaschino, E | 1 |
| Sances, G | 1 |
| Rossi, P | 1 |
| Bartolo, M | 1 |
| Pierelli, F | 1 |
| Sandrini, G | 1 |
| Nappi, G | 1 |
| Juhasz, G | 2 |
| Zsombok, T | 2 |
| Modos, EA | 1 |
| Olajos, S | 1 |
| Jakab, B | 2 |
| Nemeth, J | 2 |
| Szolcsanyi, J | 2 |
| Vitrai, J | 1 |
| Bagdy, G | 2 |
| Tvedskov, JF | 1 |
| Gibson, A | 1 |
| Wiliams, P | 1 |
| Vanmolkot, F | 1 |
| Van der Schueren, B | 1 |
| de Hoon, J | 1 |
| Thomaides, T | 1 |
| Karapanayiotides, T | 1 |
| Kerezoudi, E | 1 |
| Avramidis, T | 1 |
| Haeropoulos, C | 1 |
| Zoukos, Y | 1 |
| Spantideas, A | 1 |
| Christiansen, I | 1 |
| Ulrich, V | 1 |
| Bahra, A | 1 |
| Matharu, MS | 1 |
| Buchel, C | 1 |
| Frackowiak, RS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biomarker Identification to Predict the Evolution of Migraine From an Episodic to a Chronic Condition[NCT04696510] | 15 participants (Actual) | Observational | 2018-08-31 | Completed | |||
| A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches[NCT00391755] | Phase 4 | 4 participants (Actual) | Interventional | 2006-10-31 | Terminated (stopped due to Failure to recruit necessary number of patients.) | ||
| Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging[NCT01741246] | 78 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for nitroglycerin and Common Migraine
| Article | Year |
|---|---|
Delayed migraine-like headache in healthy volunteers after a combination of acetazolamide and glyceryl trinitrate.
Topics: Acetazolamide; Adult; Anticonvulsants; Arterioles; Blood Flow Velocity; Blood Pressure; Carbon Dioxi | 2009 |
Prednisolone reduces nitric oxide-induced migraine.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Cerebrovascular Circulation; Cross-Over Studies; D | 2009 |
Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: a double-blind, placebo-controlled, cross-over study.
Topics: Administration, Oral; Administration, Sublingual; Adult; Cross-Over Studies; Double-Blind Method; Fe | 2011 |
The prophylactic effect of valproate on glyceryltrinitrate induced migraine.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle A | 2004 |
Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack.
Topics: Biomarkers; Calcitonin Gene-Related Peptide; Female; Humans; Middle Aged; Migraine without Aura; Nit | 2005 |
Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura.
Topics: Adult; Analgesics; Female; Hemodynamics; Humans; Male; Migraine with Aura; Migraine without Aura; Ni | 1999 |
7 other studies available for nitroglycerin and Common Migraine
| Article | Year |
|---|---|
Increased nitroglycerin-mediated vasodilation in migraineurs without aura in the interictal period.
Topics: Adult; Brachial Artery; Carotid Intima-Media Thickness; Female; Humans; Male; Middle Aged; Migraine | 2018 |
Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks.
Topics: Adult; Brain; Cerebrovascular Circulation; Data Interpretation, Statistical; Disease Progression; Fe | 2014 |
Coexisting typical migraine in familial hemiplegic migraine.
Topics: Adult; Aged; Analgesics; Female; Humans; Male; Middle Aged; Migraine Disorders; Migraine with Aura; | 2010 |
NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release.
Topics: Adult; Analysis of Variance; Blood Platelets; Calcitonin Gene-Related Peptide; Case-Control Studies; | 2003 |
Sumatriptan causes parallel decrease in plasma CGRP concentration and migraine headache during nitroglycerin-induced migraine attack.
Topics: Biomarkers; Calcitonin Gene-Related Peptide; Female; Humans; Middle Aged; Migraine without Aura; Nit | 2006 |
Intravenous valproate aborts glyceryl trinitrate-induced migraine attacks: a clinical and quantitative EEG study.
Topics: Adult; Electroencephalography; Female; Humans; Infusions, Intravenous; Male; Migraine without Aura; | 2008 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |