Page last updated: 2024-11-01

nitroglycerin and Coarctation of Aorta

nitroglycerin has been researched along with Coarctation of Aorta in 9 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"Vasorelaxation by histamine, iloprost and nitroglycerin are impaired in hypertension."3.68Vascular smooth muscle responses to endothelial autacoids in rats with chronic coarctation hypertension. ( Bell, DR, 1993)
"We assessed the degree of reactive hyperemia (RH) produced after distal cuff occlusion and release and the changes in arterial diameter in response to RH (with increased flow causing endothelium-dependent dilation) and to glyceryltrinitrate (GTN, an endothelium-independent dilator)."1.29Arterial reactivity is significantly impaired in normotensive young adults after successful repair of aortic coarctation in childhood. ( Celermajer, DS; Deanfield, JE; Gardiner, HM; Georgakopoulos, D; Robinson, J; Sorensen, KE; Thomas, O, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moerman, A1
Bové, T1
François, K1
Jacobs, S1
Deblaere, I1
Wouters, P1
De Hert, S1
Ogawa, Y1
Okumura, K1
Matsui, H1
Fukami, Y1
Saburi, Y1
Iami, H1
Mizuno, T1
Nishimoto, Y1
FRICK, MH1
HALONEN, PI1
Heger, M1
Willfort, A1
Neunteufl, T1
Rosenhek, R1
Gabriel, H1
Wollenek, G1
Wimmer, M1
Maurer, G1
Baumgartner, H1
Estafanous, FG1
Tarazi, RC1
Bell, DR1
Gardiner, HM1
Celermajer, DS1
Sorensen, KE1
Georgakopoulos, D1
Robinson, J1
Thomas, O1
Deanfield, JE2
de Divitiis, M1
Pilla, C1
Kattenhorn, M1
Zadinello, M1
Donald, A1
Leeson, P1
Wallace, S1
Redington, A1
Burakovskiĭ, VI1
Bukharin, VA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
LOVE-COARCT Study: Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment[NCT03262753]90 participants (Anticipated)Observational2013-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nitroglycerin and Coarctation of Aorta

ArticleYear
Society of cardiovascular anesthesiologists: the effect of blood pressure regulation during aortic coarctation repair on brain, kidney, and muscle oxygen saturation measured by near-infrared spectroscopy: a randomized, clinical trial.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:4

    Topics: Aging; Anesthesia, Intravenous; Aortic Coarctation; Blood Pressure; Brain Chemistry; Cardiac Surgica

2013
Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery.
    Circulation, 2001, Sep-18, Volume: 104, Issue:12 Suppl 1

    Topics: Adult; Age Factors; Aortic Coarctation; Blood Flow Velocity; Brachial Artery; Cardiovascular Surgica

2001

Other Studies

7 other studies available for nitroglycerin and Coarctation of Aorta

ArticleYear
Relaxant properties mediated by nitroglycerin in aortic coarctation hypertensive rats.
    Heart and vessels, 2002, Volume: 17, Issue:2

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Blood Pressure; Charybdotoxin; Disea

2002
The flicker fusion threshold and its response to nitroglycerin in hypertension and in coarctation of the aorta.
    Acta medica Scandinavica, 1961, Volume: 169

    Topics: Aorta; Aortic Coarctation; Flicker Fusion; Humans; Hypertension; Nitrites; Nitroglycerin

1961
Vascular dysfunction after coarctation repair is related to the age at surgery.
    International journal of cardiology, 2005, Mar-18, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aortic Coarctation; Blood Vessel Prosthesis Implantation; Brachial A

2005
Systemic arterial hypertension associated with cardiac surgery.
    The American journal of cardiology, 1980, Volume: 46, Issue:4

    Topics: Angiotensin II; Antihypertensive Agents; Aortic Coarctation; Aortic Valve; Cardiac Surgical Procedur

1980
Vascular smooth muscle responses to endothelial autacoids in rats with chronic coarctation hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Autacoids; Chronic Di

1993
Arterial reactivity is significantly impaired in normotensive young adults after successful repair of aortic coarctation in childhood.
    Circulation, 1994, Volume: 89, Issue:4

    Topics: Adult; Aortic Coarctation; Blood Flow Velocity; Brachial Artery; Child, Preschool; Exercise; Female;

1994
[Basic surgical problems in congenital heart defects].
    Kardiologiia, 1969, Volume: 9, Issue:10

    Topics: Age Factors; Aortic Coarctation; Aortic Valve Stenosis; Child; Child, Preschool; Heart Defects, Cong

1969