Page last updated: 2024-11-01

nitroglycerin and Chronic Pain

nitroglycerin has been researched along with Chronic Pain in 4 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.

Research Excerpts

ExcerptRelevanceReference
"In 30 patients with chest pain and angiographically normal coronary arteries or mild atherosclerosis, we studied endothelium-dependent responses with acetylcholine (ACH) and endothelium-independent function with nitroglycerin and adenosine in the left anterior descending artery."3.77Myocardial ischaemia in patients with coronary endothelial dysfunction: insights from body surface ECG mapping and implications for invasive evaluation of chronic chest pain. ( Lennon, RJ; Lerman, A; Prasad, A; Rihal, CS; Summers, MR, 2011)
" In addition, chronic administration of nitroglycerin produces a progressive and sustained decrease in basal mechanical responses, and this hypersensitivity is blocked by migraine preventatives such as topiramate."1.46Animal Model of Chronic Migraine-Associated Pain. ( Moye, LS; Pradhan, AAA, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Snelgrove, H1
Baileff, A1
Moye, LS1
Pradhan, AAA1
Summers, MR1
Lerman, A1
Lennon, RJ1
Rihal, CS1
Prasad, A1
Steunebrink, M1
Zwerver, J1
Brandsema, R1
Groenenboom, P1
van den Akker-Scheek, I1
Weir, A1

Reviews

1 review available for nitroglycerin and Chronic Pain

ArticleYear
A review of interventions to reduce pain in chronic wounds.
    British journal of community nursing, 2019, Dec-01, Volume: 24, Issue:Sup12

    Topics: Anesthetics, Local; Apitherapy; Bandages; Chronic Disease; Chronic Pain; Collagen; Community Health

2019

Trials

1 trial available for nitroglycerin and Chronic Pain

ArticleYear
Topical glyceryl trinitrate treatment of chronic patellar tendinopathy: a randomised, double-blind, placebo-controlled clinical trial.
    British journal of sports medicine, 2013, Volume: 47, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Analgesics; Chronic Pain; Double-Blind Method; Humans;

2013

Other Studies

2 other studies available for nitroglycerin and Chronic Pain

ArticleYear
Animal Model of Chronic Migraine-Associated Pain.
    Current protocols in neuroscience, 2017, Jul-05, Volume: 80

    Topics: Animals; Association Learning; Chronic Pain; Disease Models, Animal; Female; Hyperalgesia; Mice; Mic

2017
Myocardial ischaemia in patients with coronary endothelial dysfunction: insights from body surface ECG mapping and implications for invasive evaluation of chronic chest pain.
    European heart journal, 2011, Volume: 32, Issue:22

    Topics: Acetylcholine; Adult; Blood Flow Velocity; Chest Pain; Chronic Pain; Coronary Circulation; Electroca

2011