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nitroglycerin and Chemical Dependence

nitroglycerin has been researched along with Chemical Dependence in 17 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"The optimal medical regimen for the treatment of cocaine associated myocardial ischemia has not been defined."9.07Nitroglycerin in the treatment of cocaine associated chest pain--clinical safety and efficacy. ( DiSano, MJ; Dyer, S; Fairweather, P; Feldman, JA; Fish, SS; Gennis, P; Hoffman, RS; Hollander, JE; Schumb, DA; Wax, P, 1994)
"The optimal medical regimen for the treatment of cocaine associated myocardial ischemia has not been defined."5.07Nitroglycerin in the treatment of cocaine associated chest pain--clinical safety and efficacy. ( DiSano, MJ; Dyer, S; Fairweather, P; Feldman, JA; Fish, SS; Gennis, P; Hoffman, RS; Hollander, JE; Schumb, DA; Wax, P, 1994)
"Nitrates are presently used in the therapy for angina pectoris."4.77Nitrate therapy for angina pectoris. Current concepts about mechanism of action and evaluation of currently available preparations. ( Corwin, S; Reiffel, JA, 1985)
"Sublingual glyceryl trinitrate (nitroglycerin) is the most widely used drug in the treatment of angina pectoris, but its use is limited due to its short acting effect."4.76Glyceryl trinitrate (nitroglycerin) ointment and isosorbide dinitrate: a review of their pharmacological properties and therapeutic use. ( Aronow, WS; Elkayam, U, 1982)
"Vasodilator treatment of congestive heart failure has provided an important new role for long-acting nitrates."1.26Nitrate tolerance and dependence. A critical assessment. ( Abrams, J, 1980)
"In both these models of ergotism, the directly acting vasodilator nitroglycerine (NTG) effectively relieved the ergotamine-induced arterial contractions."1.26Nitroglycerin for ergotism. Experimental studies in vitro and in migraine patients and treatment of an overt case. ( Gøthgen, I; Husum, B; Jacobsen, E; Ostergaard, JR; Rasmussen, JP; Tfelt-Hansen, P, 1982)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's2 (11.76)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WEIDLICH, F1
PAUL, O1
Abrams, J2
Martynov, AI1
Belinskaia, TF1
Elkayam, U1
Aronow, WS2
Tfelt-Hansen, P2
Ostergaard, JR1
Gøthgen, I1
Jacobsen, E1
Rasmussen, JP1
Husum, B1
Hollander, JE2
Hoffman, RS1
Gennis, P1
Fairweather, P1
DiSano, MJ1
Schumb, DA1
Feldman, JA1
Fish, SS1
Dyer, S1
Wax, P1
Schweisheimer, W1
Reichek, N1
Corwin, S1
Reiffel, JA1
Frishman, WH1
Stika, L1
Vinar, O1

Reviews

4 reviews available for nitroglycerin and Chemical Dependence

ArticleYear
Nitrate tolerance and dependence.
    American heart journal, 1980, Volume: 99, Issue:1

    Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Fail

1980
Glyceryl trinitrate (nitroglycerin) ointment and isosorbide dinitrate: a review of their pharmacological properties and therapeutic use.
    Drugs, 1982, Volume: 23, Issue:3

    Topics: Angina Pectoris; Drug Interactions; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Nitr

1982
Cocaine-associated myocardial infarction.
    Journal of the Royal Society of Medicine, 1996, Volume: 89, Issue:8

    Topics: Adult; Aged; Aspirin; Benzodiazepines; Cocaine; Humans; Middle Aged; Myocardial Infarction; Myocardi

1996
Nitrate therapy for angina pectoris. Current concepts about mechanism of action and evaluation of currently available preparations.
    Archives of internal medicine, 1985, Volume: 145, Issue:3

    Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Coronary

1985

Trials

1 trial available for nitroglycerin and Chemical Dependence

ArticleYear
Nitroglycerin in the treatment of cocaine associated chest pain--clinical safety and efficacy.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:3

    Topics: Adult; Chest Pain; Cocaine; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Myocardial Infarc

1994

Other Studies

12 other studies available for nitroglycerin and Chemical Dependence

ArticleYear
[Nitroglycerin addiction or misuse?].
    Die Medizinische Welt, 1960, Feb-27, Volume: 9

    Topics: Behavior, Addictive; Humans; Nitrites; Nitroglycerin; Substance-Related Disorders

1960
INTRACTABLE ANGINA.
    Progress in cardiovascular diseases, 1963, Volume: 6

    Topics: Anemia; Angina Pectoris; Anticoagulants; Anxiety; Cardiac Surgical Procedures; Cardiovascular Diseas

1963
Nitrate tolerance and dependence. A critical assessment.
    La Nouvelle presse medicale, 1980, Sep-25, Volume: 9, Issue:34 Suppl

    Topics: Angina Pectoris; Animals; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrate

1980
[Use of nitrates in clinical practice].
    Kardiologiia, 1980, Volume: 20, Issue:12

    Topics: Angina Pectoris; Cardiovascular System; Electrocardiography; Heart Failure; Humans; Myocardial Infar

1980
Nitroglycerin for ergotism. Experimental studies in vitro and in migraine patients and treatment of an overt case.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:2

    Topics: Adult; Arteries; Blood Pressure; Ergotamine; Ergotism; Female; Humans; In Vitro Techniques; Migraine

1982
[Nitroglycerin dependence--a new syndrome?].
    Medizinische Klinik, 1978, Oct-27, Volume: 73, Issue:43

    Topics: Humans; Nitroglycerin; Occupational Diseases; Substance-Related Disorders

1978
Clinical use of nitrates. II. Nitrates in congestive heart failure.
    Modern concepts of cardiovascular disease, 1979, Volume: 48, Issue:7

    Topics: Administration, Oral; Drug Evaluation; Heart Failure; Humans; Nitrates; Nitroglycerin; Ointments; Su

1979
Long-acting nitrates in the treatment of angina pectoris.
    JAMA, 1976, Sep-20, Volume: 236, Issue:12

    Topics: Angina Pectoris; Delayed-Action Preparations; Erythrityl Tetranitrate; Hemodynamics; Humans; Isosorb

1976
The effect of ergotamine on the arterial system in man.
    Acta pharmacologica et toxicologica, 1986, Volume: 59 Suppl 3

    Topics: Arteries; Blood Pressure; Dose-Response Relationship, Drug; Ergotamine; Ergotamines; Ergotism; Extre

1986
Pharmacology of the nitrates in angina pectoris.
    The American journal of cardiology, 1985, Dec-27, Volume: 56, Issue:17

    Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Cheek; Chemical Phenomena; Chemistry

1985
Horse doping. Pharmacology and the punter.
    Nature, 1969, Apr-12, Volume: 222, Issue:5189

    Topics: Amphetamine; Animals; Chlorpromazine; Crime; Digitalis Glycosides; Heroin; Horses; Humans; Narcotics

1969
An attempt to detect drug abuse.
    Activitas nervosa superior, 1971, Volume: 13, Issue:3

    Topics: Czechoslovakia; Digoxin; Drug Prescriptions; Electronic Data Processing; Humans; Hydrochlorothiazide

1971