Page last updated: 2024-11-01

nitroglycerin and Cardiovascular Diseases

nitroglycerin has been researched along with Cardiovascular Diseases in 131 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to compare the efficacy of nitroglycerin and diltiazem versus nitroglycerin alone in preventing radial artery spasm (RAS) during transradial coronary procedures."9.16Nitroglycerin plus diltiazem versus nitroglycerin alone for spasm prophylaxis with transradial approach. ( Dharma, S; Pancholy, S; Patel, T; Radadiya, R; Shah, S; Vyas, C, 2012)
"In this convenience sample, the response of chest pain to sublingual nitroglycerin was not a reliable indicator of a cardiac etiology."9.11Changes in the numeric descriptive scale for pain after sublingual nitroglycerin do not predict cardiac etiology of chest pain. ( Amsterdam, EA; Boghos, E; Diercks, DB; Guzman, H; Kirk, JD, 2005)
"To determine the effects of pioglitazone (30 mg once daily for 16 weeks) on insulin sensitivity, insulin-mediated vasodilation, vascular inflammatory markers, fat distribution and lipids in Asian Indians and Caucasians of European ancestry."7.73Effect of pioglitazone on insulin sensitivity, vascular function and cardiovascular inflammatory markers in insulin-resistant non-diabetic Asian Indians. ( Gerhard-Herman, MD; O'connor, ME; Raji, A; Simonson, DC; Williams, JS, 2006)
"The aim of this study was to compare the efficacy of nitroglycerin and diltiazem versus nitroglycerin alone in preventing radial artery spasm (RAS) during transradial coronary procedures."5.16Nitroglycerin plus diltiazem versus nitroglycerin alone for spasm prophylaxis with transradial approach. ( Dharma, S; Pancholy, S; Patel, T; Radadiya, R; Shah, S; Vyas, C, 2012)
" Twenty persons with cardiovascular risk (mean age 50+/-2 years) were treated with atorvastatin (80 mg/day) and FMD/NMD was measured during normoxia, hypoxia and oxygen supplementation before, after 1 day and 3 months."5.13Effect of acute changes in oxygen tension on flow-mediated dilation. Relation to cardivascular risk. ( Frøbert, O; Holmager, P; Jensen, KM; Schmidt, EB; Simonsen, U, 2008)
"In this convenience sample, the response of chest pain to sublingual nitroglycerin was not a reliable indicator of a cardiac etiology."5.11Changes in the numeric descriptive scale for pain after sublingual nitroglycerin do not predict cardiac etiology of chest pain. ( Amsterdam, EA; Boghos, E; Diercks, DB; Guzman, H; Kirk, JD, 2005)
" Forearm blood flow (FBF) was measured by strain-gauge plethysmography during reactive hyperemia to assess endothelium-dependent vasodilation and after sublingual nitroglycerin (NTG) administration to assess endothelium-independent vasodilation."5.09Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women. ( Chayama, K; Goto, C; Higashi, Y; Matsuura, H; Nakagawa, K; Ohama, K; Oshima, T; Sanada, M; Sasaki, S, 2001)
" "Early entry" therapy with nitrates do not significantly improve survival in myocardial infarction but increases the beneficial effects of the ACE-inhibitor enalapril by 50%."4.82Organic nitrates in cardiovascular disease. ( Bode-Böger, SM; Kojda, G, 2005)
"Cardiovascular diseases and their treatment in the aged are discussed under the headings of ischemic heart disease, hypertension, cardiac failure (with special reference to the use of diuretics and digoxin), infective carditis and thyroid disorders."4.75Drug therapy for cardiovascular disease in the aged. ( Kennedy, RD, 1975)
" Considering the mechanism underlying the vasodilatory response of the brachial artery to reactive hyperemia, hyperemic shear stress (HSS), a stimulus for FMD; nitroglycerine-induced vasodilation (NID), an index of endothelium-independent vasodilation; and baseline brachial artery diameter (BAD) are also involved in vasodilatory response."3.85Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors. ( Aibara, Y; Chayama, K; Goto, C; Hashimoto, H; Hida, E; Hidaka, T; Higashi, Y; Iwamoto, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oda, N; Yusoff, FM, 2017)
"We measured nitroglycerine-induced vasodilation and FMD in 436 subjects who underwent health examinations (mean age, 53 ± 19 years; age range, 19-86 years), including patients with cardiovascular diseases."3.79Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation. ( Chayama, K; Fujimura, N; Goto, C; Hidaka, T; Higashi, Y; Idei, N; Iwamoto, Y; Kajikawa, M; Kihara, Y; Maruhashi, T; Matsumoto, T; Mikami, S; Nakashima, A; Noma, K; Soga, J, 2013)
"We measured brachial IMT, FMD, and nitroglycerine-induced vasodilation by ultrasound in 388 subjects who underwent health examination (mean age, 45±22 years; age range, 19-86), including patients with cardiovascular diseases."3.78Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors. ( Chayama, K; Fujii, Y; Fujimura, N; Higashi, Y; Idei, N; Iwamoto, Y; Kajikawa, M; Kihara, Y; Maruhashi, T; Matsumoto, T; Mikami, S; Nakashima, A; Noma, K, 2012)
"To determine the effects of pioglitazone (30 mg once daily for 16 weeks) on insulin sensitivity, insulin-mediated vasodilation, vascular inflammatory markers, fat distribution and lipids in Asian Indians and Caucasians of European ancestry."3.73Effect of pioglitazone on insulin sensitivity, vascular function and cardiovascular inflammatory markers in insulin-resistant non-diabetic Asian Indians. ( Gerhard-Herman, MD; O'connor, ME; Raji, A; Simonson, DC; Williams, JS, 2006)
"As part of the Women's Ischemia Syndrome Evaluation (WISE) sponsored by the National Heart, Lung, and Blood Institute, 163 women referred for clinically indicated coronary angiography underwent coronary reactivity assessment with quantitative coronary angiography and intracoronary Doppler flow before and after intracoronary administration of acetylcholine, adenosine, and nitroglycerin and were then followed up for clinical outcomes."3.72Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). ( Arant, CB; Bairey Merz, CN; Handberg, E; Johnson, BD; Kerensky, RA; McGorray, SP; Olson, MB; Pepine, CJ; Sharaf, BL; Smith, KM; Sopko, G; von Mering, GO; Wessel, TR, 2004)
"Children with type 1 diabetes have vascular dysfunction preceding atherosclerosis."2.84Effect of Metformin on Vascular Function in Children With Type 1 Diabetes: A 12-Month Randomized Controlled Trial. ( Anderson, JJA; Coppin, B; Couper, JJ; Gent, R; Giles, LC; Leggett, CE; Peña, AS, 2017)
" As such, a higher dosage of GTN is required in order to achieve the same vasodilatory and antiplatelet effects."2.82The Generation of Nitric Oxide from Aldehyde Dehydrogenase-2: The Role of Dietary Nitrates and Their Implication in Cardiovascular Disease Management. ( Bosco, F; Cardamone, A; Carresi, C; Coppoletta, A; Gliozzi, M; Macrì, R; Maiuolo, J; Mollace, R; Mollace, V; Muscoli, C; Musolino, V; Oppedisano, F; Palma, E; Scarano, F, 2022)
" Only 1 method of preventing nitrate tolerance remains widely accepted: the use of a dosing strategy that provides an interval of no or low nitrate exposure during each 24-h period."2.55The Role of Nitroglycerin and Other Nitrogen Oxides in Cardiovascular Therapeutics. ( Divakaran, S; Loscalzo, J, 2017)
"Erectile dysfunction is a frequent condition in cardiovascular patients."2.41[Drug treatment of erection disorders in patients with cardiovascular disease]. ( Kingma, JH; Meuleman, EJ, 2001)
" In conclusion, transdermal nitroglycerin patches offer a convenient and cosmetically acceptable dosage form which has potential use in stable angina if administered as an intermittent regimen providing a patch-free period each night."2.38Transdermal nitroglycerin (glyceryl trinitrate). A review of its pharmacology and therapeutic use. ( Goa, KL; Langtry, HD; Todd, PA, 1990)
" Finally, appropriate dosing strategies are suggested that should eliminate the potential problem of nitrate tolerance."2.37Nitrates. ( Abrams, J, 1988)
"Intermittent nocturnal hypoxemia, obesity and impaired glucose control are early predictors of vascular decline during postmenopause."1.91Effect of menopause and age on vascular impairment. ( Aittokallio, J; Hautajärvi, T; Heinonen, O; Kalleinen, N; Polo, O; Raitakari, O; Riskumäki, M; Saaresranta, T; Vahlberg, T, 2023)
"Childhood obesity is associated with premature cardiovascular complications."1.48Serum cardiovascular risk biomarkers in pre-pubertal obese children. ( Aggoun, Y; Beghetti, M; Farpour-Lambert, NJ; Galan, K; Mach, F; Maggio, ABR; Montecucco, F, 2018)
"Cardiovascular diseases are associated with chronic activation of Rho-associated kinases (ROCKs) and endothelial dysfunction."1.37Rho-associated kinase activity, endothelial function, and cardiovascular risk factors. ( Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J, 2011)
"Endothelium-dependent reactive hyperemia (RH%) and endothelium-independent nitrate hyperemia dilatation (NH%) were measured by strain gauge plethysmography."1.35Inflammatory and thrombotic processes are associated with vascular dysfunction in children with familial hypercholesterolemia. ( Antoniades, C; Charakida, M; Latsios, G; Pitsavos, C; Siasos, G; Skoumas, I; Stefanadi, E; Stefanadis, C; Tousoulis, D; Vasiliadou, C, 2009)
"In particular, the prevalence of carotid atherosclerosis (28% vs."1.35High prevalence of subclinical cardiovascular abnormalities in patients with systemic lupus erythematosus in spite of a very low clinical damage index. ( Celentano, A; Di Minno, MN; Lupo, T; Migliaresi, P; Orefice, M; Palmieri, V; Valentini, G, 2009)
"In vitro and animal studies demonstrate that myeloperoxidase catalytically consumes nitric oxide as a substrate, limiting its bioavailability and function."1.32Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. ( Brennan, ML; Gokce, N; Goormastic, M; Hazen, SL; Keaney, JF; Mann, SA; Penn, MS; Shishehbor, MH; Vita, JA, 2004)
"Type 2 diabetes is associated with an increased risk of cardiovascular disease."1.31Impaired vascular reactivity is present despite normal levels of von Willebrand factor in patients with uncomplicated Type 2 diabetes. ( Eskildsen, PC; Ihlemann, N; Stokholm, KH, 2002)
"Nitrates have been used for the last 130 years to treat and control the symptoms of angina pectoris."1.28Nitrates. ( Kuhn, M, 1992)
" With the conventional tablet and capsule dosage forms, the amount of drug absorbed through the gastrointestinal (GI) tract varies depending on the quantity and types of food in the stomach, on the GI motility and transit time."1.27Transdermal absorption of nitroglycerin from microseal drug delivery (MDD) system. ( Karim, A, 1983)
"Nitroglycerin was used to treat systemic or pulmonary hypertension, myocardial ischaemia and ventricular failure."1.27A profile of intravenous nitroglycerin use in cardiopulmonary bypass surgery. ( Bessette, MC; Cohen, AY; Townsend, GE; Whalley, DG; Wynands, JE, 1983)
"Increased mortality from cardio-cerebrovascular diseases among male dynamite workers was reported in 1977 and was supported two years later by findings in a small cohort study from another Swedish dynamite population."1.27Mortality from cardio-cerebrovascular diseases among dynamite workers--an extended case-referent study. ( Axelson, O; Hogstedt, C, 1984)
"Isosorbide dinitrate was independently synthesised in the United States by Harris and colleagues in the 1950s."1.27Historical aspects of nitrate therapy. ( Berlin, R, 1987)

Research

Studies (131)

TimeframeStudies, this research(%)All Research%
pre-199035 (26.72)18.7374
1990's16 (12.21)18.2507
2000's43 (32.82)29.6817
2010's31 (23.66)24.3611
2020's6 (4.58)2.80

Authors

AuthorsStudies
Pewowaruk, RJ1
Hein, AJ1
Carlsson, CM1
Korcarz, CE1
Gepner, AD1
Maiuolo, J1
Oppedisano, F1
Carresi, C1
Gliozzi, M1
Musolino, V1
Macrì, R1
Scarano, F1
Coppoletta, A1
Cardamone, A1
Bosco, F1
Mollace, R1
Muscoli, C1
Palma, E1
Mollace, V1
Aittokallio, J1
Saaresranta, T1
Riskumäki, M1
Hautajärvi, T1
Vahlberg, T1
Polo, O1
Heinonen, O1
Raitakari, O1
Kalleinen, N1
Maruhashi, T8
Kajikawa, M5
Kishimoto, S3
Hashimoto, H2
Takaeko, Y1
Yamaji, T1
Harada, T1
Han, Y1
Aibara, Y3
Mohamad Yusoff, F1
Hidaka, T6
Kihara, Y9
Chayama, K9
Nakashima, A6
Goto, C6
Tomiyama, H1
Takase, B1
Kohro, T1
Suzuki, T1
Ishizu, T1
Ueda, S1
Yamazaki, T1
Furumoto, T1
Kario, K1
Inoue, T1
Koba, S1
Watanabe, K1
Takemoto, Y1
Hano, T1
Sata, M1
Ishibashi, Y1
Node, K1
Maemura, K1
Ohya, Y1
Furukawa, T1
Ito, H1
Ikeda, H1
Yamashina, A1
Higashi, Y10
Pandurevic, S1
Bergamaschi, L1
Pizzi, C1
Patton, L1
Rucci, P1
Corzani, F1
Cecchetti, C1
Pelusi, C1
Altieri, P1
Vicennati, V1
Di Dalmazi, G1
Fanelli, F1
Macut, D1
Pagotto, U1
Gambineri, A1
Ma, WJ1
Yin, YC1
Zhang, BK1
Li, YJ1
Li, WQ1
Kopel, T1
Kaufman, JS1
Hamburg, N1
Sampalis, JS1
Vita, JA3
Dember, LM1
Anderson, JJA1
Couper, JJ1
Giles, LC1
Leggett, CE1
Gent, R1
Coppin, B1
Peña, AS1
Divakaran, S1
Loscalzo, J2
Iwamoto, Y5
Oda, N2
Matsui, S2
Yusoff, FM1
Noma, K6
Hida, E2
Maggio, ABR1
Farpour-Lambert, NJ1
Aggoun, Y1
Galan, K1
Montecucco, F1
Mach, F1
Beghetti, M1
Soga, J4
Fujimura, N4
Idei, N4
Mikami, S4
Matsumoto, T3
Hu, YJ1
Wei, AN1
Chook, P1
Yin, Y1
Cheng, W1
Wu, MJ1
Celermajer, DS1
Woo, KS1
Gilbert, SE1
Tew, GA1
Bourke, L1
Winter, EM1
Rosario, DJ1
Jones, A1
Vennelle, M1
Connell, M1
McKillop, G1
Newby, DE1
Douglas, NJ1
Riha, RL1
Wong, CK1
Chen, Y1
Ho, LM1
Zhen, Z1
Siu, CW2
Tse, HF2
Yiu, KH2
Gad, MZ1
Abu el Maaty, MA1
El-Maraghy, SA1
Fahim, AT1
Hamdy, MA1
Chan, YH1
Lau, KK1
Yiu, YF1
Li, SW1
Lam, TH1
Lau, CP1
Zhang, P1
Iwamoto, A1
Akcakoyun, M1
Kargin, R1
Tanalp, AC1
Pala, S1
Ozveren, O1
Akcay, M1
Barutcu, I1
Kirma, C1
Mosca, M1
Virdis, A1
Tani, C1
Ghiadoni, L1
Versari, D1
Duranti, E1
d'Ascanio, A1
Salvetti, A1
Taddei, S1
Bombardieri, S1
Sugawara, M1
Niki, K1
Ohte, N1
Okada, T1
Harada, A1
Stamler, JS1
LUND, F1
Charakida, M1
Tousoulis, D1
Skoumas, I1
Pitsavos, C1
Vasiliadou, C1
Stefanadi, E1
Antoniades, C1
Latsios, G1
Siasos, G1
Stefanadis, C1
Palmieri, V1
Migliaresi, P1
Orefice, M1
Lupo, T1
Di Minno, MN1
Valentini, G1
Celentano, A1
Xu, JZ1
Zhang, Y1
Wu, SN1
Niu, WQ1
Zhu, DL1
Gao, PJ1
Rus, R1
Buturović-Ponikvar, J1
Wierzbicka-Chmiel, J1
Mizia-Stec, K1
Haberka, M1
Chmiel, A1
Mizia, M1
Gasior, Z1
Matsuoka, H1
Umei, H1
Sugano, R1
Fujii, Y4
Imaizumi, T1
Saihara, K1
Hamasaki, S1
Ishida, S1
Kataoka, T1
Yoshikawa, A1
Orihara, K1
Ogawa, M1
Oketani, N1
Fukudome, T1
Atsuchi, N1
Shinsato, T1
Okui, H1
Kubozono, T1
Ichiki, H1
Kuwahata, S1
Mizoguchi, E1
Fujita, S1
Takumi, T1
Ninomiya, Y1
Tomita, K1
Tei, C1
Nguyen, PK1
Katikireddy, CK1
McConnell, MV1
Kushida, C1
Yang, PC1
Akamatsu, D1
Sato, A1
Goto, H2
Watanabe, T1
Hashimoto, M1
Shimizu, T1
Sugawara, H1
Sato, H1
Nakano, Y1
Miura, T1
Zukeran, T1
Serizawa, F1
Hamada, Y1
Tsuchida, K1
Tsuji, I1
Satomi, S1
Lockhart, CJ1
Agnew, CE1
McCann, A1
Hamilton, PK1
Quinn, CE1
McCall, DO1
Plumb, RD1
McClenaghan, VC1
McGivern, RC1
Harbinson, MT1
McVeigh, GE1
Mamedov, MN1
Digigova, RT1
Sharvadze, GG1
Ugurchieva, ZO1
Kovrigina, MN1
Stroeva, MV1
Quinaglia, T1
Martins, LC2
Figueiredo, VN1
Santos, RC1
Yugar-Toledo, JC2
Martin, JF1
Demacq, C1
Pimenta, E1
Calhoun, DA1
Moreno, H2
Lorbeer, R2
Empen, K2
Dörr, M2
Arndt, M1
Schipf, S1
Nauck, M2
Wallaschofski, H2
Felix, SB2
Völzke, H2
Sandoo, A1
Carroll, D1
Metsios, GS1
Kitas, GD1
Veldhuijzen van Zanten, JJ1
Hata, T1
Kato, H1
Liao, JK1
Haring, R1
Gläser, S1
Krebs, A1
Reffelmann, T1
Ewert, R1
Dharma, S1
Shah, S1
Radadiya, R1
Vyas, C1
Pancholy, S1
Patel, T1
Schmidt, K1
Neubauer, A1
Kolesnik, B1
Stasch, JP1
Werner, ER1
Gorren, AC1
Mayer, B1
Teragawa, H1
Ruel, G1
Lapointe, A1
Pomerleau, S1
Couture, P1
Lemieux, S1
Lamarche, B1
Couillard, C1
Hisasue, S1
Sato, Y1
Tsukamoto, T1
Gori, T1
Parker, JD2
Campuzano, R1
Moya, JL1
García-Lledó, A1
Salido, L1
Guzmán, G1
Tomas, JP1
Catalán, P1
Muriel, A1
Asín, E1
PAUL, O1
KELSER, GA1
Lubner, GC1
Girdler, SS1
Hinderliter, AL1
Wells, EC1
Sherwood, A1
Grewen, KM1
Light, KC1
FOX, EL1
WRIGHT, IS1
RUSSEK, HI1
ANDERSON, WH1
DOERNER, AA1
KEYS, A1
SIMONSON, E1
HOPKINS, RW1
von Mering, GO1
Arant, CB1
Wessel, TR1
McGorray, SP1
Bairey Merz, CN1
Sharaf, BL1
Smith, KM1
Olson, MB1
Johnson, BD1
Sopko, G1
Handberg, E1
Pepine, CJ1
Kerensky, RA1
Brennan, ML1
Gokce, N1
Mann, SA1
Goormastic, M1
Shishehbor, MH1
Penn, MS1
Keaney, JF1
Hazen, SL1
KRASNO, LR1
IVY, AC1
Spijkerman, AM1
Smulders, YM1
Kostense, PJ1
Henry, RM1
Becker, A1
Teerlink, T1
Jakobs, C1
Dekker, JM1
Nijpels, G1
Heine, RJ1
Bouter, LM1
Stehouwer, CD1
Pauca, AL1
Kon, ND1
O'Rourke, MF1
Silvestri, A1
Gambacciani, M1
Vitale, C1
Monteleone, P1
Ciaponi, M1
Fini, M1
Genazzani, AR1
Mercuro, G1
Rosano, GM1
Diercks, DB1
Boghos, E1
Guzman, H1
Amsterdam, EA1
Kirk, JD1
Bode-Böger, SM1
Kojda, G1
Zheng, H1
Huang, X1
Zhang, Q1
Katz, SD1
Paradisi, G1
Biaggi, A1
Savone, R1
Ianniello, F1
Tomei, C1
Caforio, L1
Caruso, A1
Raji, A1
Gerhard-Herman, MD1
Williams, JS1
O'connor, ME1
Simonson, DC1
Lane, HA1
Grace, F1
Smith, JC1
Morris, K1
Cockcroft, J1
Scanlon, MF2
Davies, JS2
Greenland, P1
Dogra, G1
Irish, A1
Chan, D1
Watts, G1
Fink, B1
Dikalov, S1
Fink, N1
Shechter, M2
Marai, I2
Marai, S1
Sherer, Y1
Sela, BA1
Feinberg, MS2
Rubinstein, A1
Shoenfeld, Y1
Sahin, G1
Yalcin, AU1
Akcar, N1
Frøbert, O1
Holmager, P1
Jensen, KM1
Schmidt, EB1
Simonsen, U1
Rubira, MC1
Consolim-Colombo, FM1
Rabelo, ER1
Casarini, D1
Coimbra, SR1
Krieger, EM1
Irigoyen, MC1
Anderson, T1
Charbonneau, F1
Chan, S1
Lonn, E1
Andrade, AC1
Ladeia, AM1
Netto, EM1
Mascarenhas, A1
Cotter, B1
Benson, CA1
Badaró, R1
Issachar, A1
Koren-Morag, N1
Freinark, D1
Shahar, Y1
Shechter, A1
Cárdenas Loaeza, M1
Karim, A1
Townsend, GE1
Wynands, JE1
Whalley, DG1
Cohen, AY1
Bessette, MC1
Spector, R1
Hogstedt, C1
Axelson, O1
Abrams, J3
Tritthart, HA1
Steingart, RM1
Wexler, JP1
Blaufox, MD1
Bourbonnais, F1
Halawa, B1
Utoh, J1
Miyauchi, Y1
Obayashi, H1
Hirata, T1
Vallance, P1
Moncada, S1
Chen, CH1
Ting, CT1
Nussbacher, A1
Nevo, E1
Kass, DA1
Pak, P1
Wang, SP1
Chang, MS1
Yin, FC1
Eagle, KA1
Brundage, BH1
Chaitman, BR1
Ewy, GA1
Fleisher, LA1
Hertzer, NR1
Leppo, JA1
Ryan, T1
Schlant, RC1
Spencer, WH1
Spittell, JA1
Twiss, RD1
Ritchie, JL1
Cheitlin, MD1
Gardner, TJ1
Garson, A1
Lewis, RP1
Gibbons, RJ1
O'Rourke, RA1
Ryan, TJ1
Parker, JA1
Kawano, H1
Motoyama, T1
Kugiyama, K1
Hirashima, O1
Ohgushi, M1
Fujii, H1
Ogawa, H1
Yasue, H1
Harrison, DG1
Johansson, J3
Jensen-Urstad, K3
Jensen-Urstad, M2
Evans, LM1
Goodfellow, J1
Rees, JA1
Meuleman, EJ1
Kingma, JH1
Sanada, M1
Sasaki, S1
Nakagawa, K1
Matsuura, H1
Ohama, K1
Oshima, T1
Irwin, MG1
Ng, JK1
Duchna, HW1
Guilleminault, C1
Stoohs, RA1
Orth, M1
de Zeeuw, J1
Schultze-Werninghaus, G1
Rasche, K1
Kinlay, S1
Creager, MA1
Fukumoto, M1
Hikita, H1
Fang, JC1
Selwyn, AP1
Ganz, P1
Ihlemann, N1
Stokholm, KH1
Eskildsen, PC1
Kennedy, RD1
Glasser, SP1
Hathaway, JA1
Arora, BK1
McIntyre, KM1
Lambrew, CT1
Freeman, J1
Stayner, LT1
Dannenberg, AL1
Thun, M1
Reeve, G1
Bloom, TF1
Boeniger, M1
Halperin, W1
Kuhn, M1
Shub, C1
Todd, PA1
Goa, KL1
Langtry, HD1
Kristensen, TS1
Lindvall, K1
Berlin, R1
Kamei, K1
Aizawa, Y1
Shibata, A1
Takeuchi, Y1
Ishii, M1
Langnickel, R1
Bluth, R1
Almeyda, J1
Levantine, A1
Fiehring, H1
Vormittag, E1
Zekert, F1
Kohn, P1
Grabner, H1
Vormittag, D1
Takenaka, F1
Lapin, BA1
Cherkovich, GM1
Iakovleva, LA1
Heuillet, G1
Saadjian, A1
Couve, M1
Soulier, R1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Flow-mediated Arterial Dilatation, Hypertension, Endothelin-1 (ET-1) and Soluble Intercellular Adhesion Molecule (sICAM-1) in Obese Adolescents[NCT05951894]70 participants (Actual)Observational [Patient Registry]2023-08-01Completed
Safety and Tolerability of Topical Nitroglycerin to Dilate the Radial Artery Prior to Transradial Coronary Angiography[NCT05239013]Early Phase 120 participants (Anticipated)Interventional2022-05-01Not yet recruiting
Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain[NCT03026101]20 participants (Anticipated)Interventional2017-01-31Enrolling by invitation
Perioperative Endothelial Dysfunction in Patients Undergoing Minor Abdominal Surgery. The POETRY Minor Study.[NCT02690233]60 participants (Actual)Observational2016-02-29Completed
Effect of Androgen Deprivation Therapy on Left Ventricular Function in Prostate Cancer Patients and Survivors[NCT03275181]60 participants (Anticipated)Observational2017-08-01Recruiting
The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in Humans[NCT02490124]7 participants (Actual)Observational2014-12-31Completed
The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 Diabetes[NCT03174288]32 participants (Actual)Interventional2015-08-31Completed
Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638]240 participants (Anticipated)Interventional2015-10-31Not yet recruiting
[NCT00000554]Phase 30 participants Interventional2001-05-31Completed
Non-invasive Fractional Flow Reserve CT (FFRCT) Scan for the Study of Coronary Vaso-motion[NCT02809157]10 participants (Anticipated)Observational2014-10-31Active, not recruiting
The Effects of Traditional Acupuncture on Mechanisms of Coronary Heart Disease[NCT00570024]145 participants (Actual)Interventional2006-01-31Completed
WISE Ancillary Study Data Analyses: Efficacy of Hormone Replacement on Myocardial Ischemia in Postmenopausal Women With Normal/Minimal Coronary Artery Disease: Data Analysis[NCT00600106]37 participants (Actual)Interventional1999-12-31Completed
Nitrative Stress in Heart Failure: The Cleveland Heart and Metabolic Prevention Study (CHAMPS)[NCT03012022]1,208 participants (Actual)Observational2010-11-30Active, not recruiting
Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study[NCT02333240]101 participants (Actual)Interventional2015-04-30Completed
Gender-Specific Effects of Physiologic GH Administration on Cardiovascular Risk Factors in Women With Growth Hormone Deficiency[NCT00136032]63 participants (Actual)Interventional2002-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Endothelial Dysfunction (FMD)

"Endothelial dysfunction refers to altered vasoactive, anticoagulant, and anti-inflammatory properties of endothelium, and dysregulated vascular growth remodeling that results from a loss of nitric oxide (NO) bioactivity in the endothelium. Brachial Artery Reactivity Testing (BART), high-frequency ultrasonographic imaging of the brachial artery, evaluates flow-mediated vasodilation (FMD), an endothelium-dependent function. The technique provokes the release of nitric oxide, resulting in vasodilation that can be quantitated as an index of endothelial dysfunction.~Flow-mediated vasodilation is typically expressed as the change in post-stimulus diameter as a percentage of the baseline diameter [diameter after cuff deflation - baseline diameter / baseline diameter) x 100]." (NCT00600106)
Timeframe: Baseline

Interventionpercentage of pre-stimulus diameter (Mean)
Hormone Replacement Therapy8.2
Placebo8.8

Endothelial Dysfunction (FMD)

"Endothelial dysfunction refers to altered vasoactive, anticoagulant, and anti-inflammatory properties of endothelium, and dysregulated vascular growth remodeling that results from a loss of nitric oxide (NO) bioactivity in the endothelium. Brachial Artery Reactivity Testing (BART), high-frequency ultrasonographic imaging of the brachial artery, evaluates flow-mediated vasodilation (FMD), an endothelium-dependent function. The technique provokes the release of nitric oxide, resulting in vasodilation that can be quantitated as an index of vasomotor function.~Flow-mediated vasodilation is typically expressed as the change in post-stimulus diameter as a percentage of the baseline diameter [diameter after cuff deflation - baseline diameter / baseline diameter) x 100]." (NCT00600106)
Timeframe: 12 weeks

Interventionpercentage of pre-stimulus diameter (Mean)
Hormone Replacement Therapy8.8
Placebo7.3

Inducible Myocardial Ischemia

Inducible myocardial ischemia measured by P-31 gated magnetic resonance cardiac spectroscopy (MRS) is reported as change (∆) in PCr/ATP ratio, with isometric submaximal handgrip stress. PCr/ATP ratio defined as (stress-[average of rest and recovery periods]) / average of rest and recover periods X 100, and expressed as % mean ± SD. For this trial, myocardial ischemia was pre-specified as a fall in quantitative PCR/ATP ratio >20% from rest, and a lower value is considered indicative of greater ischemia. (NCT00600106)
Timeframe: 12 weeks

Interventionpercent change in PCR/ATP ratio (Mean)
Hormone Replacement Therapy-7.7
Placebo1.1

Inducible Myocardial Ischemia

Inducible myocardial ischemia measured by P-31 gated magnetic resonance cardiac spectroscopy (MRS) is reported as change (∆) in PCr/ATP ratio, with isometric submaximal handgrip stress. PCr/ATP ratio defined as (stress-[average of rest and recovery periods]) / average of rest and recover periods X 100, and expressed as % mean ± SD. For this trial, myocardial ischemia was pre-specified as a fall in quantitative PCR/ATP ratio >20% from rest, and a lower value is considered indicative of greater ischemia. (NCT00600106)
Timeframe: Baseline

Interventionpercent changed in PCR/ATP ratio (Mean)
Hormone Replacement Therapy-13.8
Placebo-7.0

Physical Functional Disability - Functional Capacity (Exercise Induced ST Segment Depression)

"Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain.~In electrocardiography, the ST segment connects the QRS complex and the T wave and has duration of 80 to 120 ms. It should be essentially level with the PR and TP segment. The normal ST segment has a slight upward concavity. Flat, downsloping, or depressed ST segment may indicate coronary ishcemia. Positive treadmill exercise stress test (>1.0 mm horizontal / downsloping or >1.5 upsloping ST segment depression measured 0.08 msec after the J point)." (NCT00600106)
Timeframe: Baseline

Interventionmm (Mean)
Hormone Replacement Therapy-0.79
Placebo-0.79

Physical Functional Disability - Functional Capacity (Metabolism Equivalents)

Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. (NCT00600106)
Timeframe: Baseline

Interventionmetabolism equivalents (Mean)
Hormone Replacement Therapy6.1
Placebo5.8

Physical Functional Disability - Functional Capacity (Metabolism Equivalents)

Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. (NCT00600106)
Timeframe: Exit (12 weeks)

Interventionmetabolism equivalents (Mean)
Hormone Replacement Therapy6.1
Placebo5.4

Physical Functional Disability - Functional Capacity (METs)

Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. A MET is defined as the resting metabolic rate, that is, the amount or oxygen consumet at rest, sitting quietly in a chair, approximately 3.5 ml O2 / kg / min (1.2 kcallmin for a 70-kg person). As such, work at METs requires twice the resting metabolism or 7.0 ml O2/kg/min, and so on. (NCT00600106)
Timeframe: Baseline

Interventionmetabolism equivalents (Mean)
Hormone Replacement Therapy5.4
Placebo5.4

Physical Functional Disability - Functional Capacity (METs)

Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. A MET is defined as the resting metabolic rate, that is, the amount or oxygen consumet at rest, sitting quietly in a chair, approximately 3.5 ml O2 / kg / min (1.2 kcallmin for a 70-kg person). As such, work at METs requires twice the resting metabolism or 7.0 ml O2/kg/min, and so on. (NCT00600106)
Timeframe: Exit at 12 weeks

Interventionmetabolism equivalents (Mean)
Hormone Replacement Therapy6.1
Placebo5.4

Physical Functional Disability - Functional Capacity (Stress Induced ST Segment Depression)

"Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain.~In electrocardiography, the ST segment connects the QRS complex and the T wave and has duration of 80 to 120 ms. It should be essentially level with the PR and TP segment. The normal ST segment has a slight upward concavity. Flat, downsloping, or depressed ST segment may indicate coronary ishcemia. Positive treadmill exercise stress test (>1.0 mm horizontal / downsloping or >1.5 upsloping ST segment depression measured 0.08 msec after the J point)." (NCT00600106)
Timeframe: Exit (12 weeks)

Interventionmm (Mean)
Hormone Replacement Therapy-1.05
Placebo-0.63

Quality of Life - Health Survey

"Quality of life assessed by cardiac symptoms and psychological questionnaires (SF 36 scale - Short Form Health Survey) The SF-36 includes one multi-item scale that assesses eight health concepts: 1) limitations in physical activities because of health problems; 2) limitations in social activities because of physical or emotional problems; 3) limitations in usual role activities because of physical health problems; 4) bodily pain; 5) general mental health (psychological distress and well-being); 6) limitations in usual role activities because of emotional problems; 7) vitality (energy and fatigue); and 8) general health perceptions.~Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability." (NCT00600106)
Timeframe: 12 weeks

,
Interventionunits on a scale (Mean)
Physical functioningRole-physicalRole-emotionalBodily painGeneral healthMental healthVitalitySocial functioning
Hormone Replacement Therapy59.458.876.554.555.266.435.659.4
Placebo44.425.066.741.557.269.341.256.1

Quality of Life - Health Survey

"Quality of life assessed by cardiac symptoms and psychological questionnaires (SF 36 scale - Short Form Health Survey) The SF-36 includes one multi-item scale that assesses eight health concepts: 1) limitations in physical activities because of health problems; 2) limitations in social activities because of physical or emotional problems; 3) limitations in usual role activities because of physical health problems; 4) bodily pain; 5) general mental health (psychological distress and well-being); 6) limitations in usual role activities because of emotional problems; 7) vitality (energy and fatigue); and 8) general health perceptions.~Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability." (NCT00600106)
Timeframe: Baseline

,
Interventionunits on a scale (Mean)
Physical functioningRole-physicalRole-emotionalBodily painGeneral healthMental healthVitalitySocial functioning
Hormone Replacement Therapy60.854.270.353.355.466.735.659.4
Placebo43.837.366.742.157.465.742.953.2

Quality of Life - Menopause Symptoms

Quality of life assessed by menopausal symptoms and psychological questionnaires (NCT00600106)
Timeframe: 12 weeks

,
Interventionpercent of participants (Number)
Hot flushes or flashingPoor memoryChange in sexual desireVaginal drynessAvoiding intimacy
Hormone Replacement Therapy4159353524
Placebo8978676756

Quality of Life - Menopause Symptoms

Quality of life assessed by menopausal symptoms and psychological questionnaires (NCT00600106)
Timeframe: Baseline

,
Interventionpercent of participants (Number)
Hot flushes or flashingPoor memoryChange in sexual desireVaginal drynessAvoiding intimacy
Hormone Replacement Therapy8976504439
Placebo6853375837

Reviews

20 reviews available for nitroglycerin and Cardiovascular Diseases

ArticleYear
The Generation of Nitric Oxide from Aldehyde Dehydrogenase-2: The Role of Dietary Nitrates and Their Implication in Cardiovascular Disease Management.
    International journal of molecular sciences, 2022, Dec-07, Volume: 23, Issue:24

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Cardiovascular Diseases; Humans; Nitr

2022
Calcitonin gene‑related peptide‑mediated pharmacological effects in cardiovascular and gastrointestinal diseases (Review).
    Molecular medicine reports, 2021, Volume: 23, Issue:1

    Topics: Calcitonin Gene-Related Peptide; Cardiovascular Diseases; Gastrointestinal Diseases; Gene Expression

2021
The Role of Nitroglycerin and Other Nitrogen Oxides in Cardiovascular Therapeutics.
    Journal of the American College of Cardiology, 2017, Nov-07, Volume: 70, Issue:19

    Topics: Animals; Cardiovascular Agents; Cardiovascular Diseases; Drug Administration Routes; Humans; Nitroge

2017
Assessment of endothelium-independent vasodilation: from methodology to clinical perspectives.
    Journal of hypertension, 2018, Volume: 36, Issue:7

    Topics: Angiography; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Coronary Vessels; Endotheliu

2018
[Detection of erectile dysfunction and peculiarities of its treatment in men with high cardiovascular risk].
    Kardiologiia, 2010, Volume: 50, Issue:11

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Cardiovascul

2010
[Adverse events and drug interactions of sildenafil].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 6

    Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Interactions; Erectile Dysfun

2002
The puzzle of nitrate tolerance: pieces smaller than we thought?
    Circulation, 2002, Oct-29, Volume: 106, Issue:18

    Topics: Animals; Autonomic Nervous System; Blood Vessels; Cardiovascular Diseases; Drug Tolerance; Endotheli

2002
Organic nitrates in cardiovascular disease.
    Cellular and molecular biology (Noisy-le-Grand, France), 2005, Sep-05, Volume: 51, Issue:3

    Topics: Angina, Unstable; Animals; Cardiovascular Diseases; Cyclic GMP; Enalapril; Endothelium, Vascular; He

2005
Nitrate tolerance and dependence.
    American heart journal, 1980, Volume: 99, Issue:1

    Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Fail

1980
[Complications associated with sudden withdrawal of various drugs used in the treatment of cardiovascular diseases].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Mar-15, Volume: 34, Issue:6

    Topics: Cardiovascular Diseases; Clonidine; Guanethidine; Humans; Nitroglycerin; Nitroprusside; Propranolol;

1981
Organic nitrates: new formulations and their clinical advantages.
    The American journal of cardiology, 1996, May-30, Volume: 77, Issue:13

    Topics: Cardiovascular Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Randomized Controlle

1996
Endothelial function and oxidant stress.
    Clinical cardiology, 1997, Volume: 20, Issue:11 Suppl 2

    Topics: Angiotensin II; Animals; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hydrogen Peroxide;

1997
[Drug treatment of erection disorders in patients with cardiovascular disease].
    Nederlands tijdschrift voor geneeskunde, 2001, Jan-27, Volume: 145, Issue:4

    Topics: Cardiovascular Diseases; Contraindications; Drug Interactions; Erectile Dysfunction; Humans; Isosorb

2001
Drug therapy for cardiovascular disease in the aged.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Bacterial Agents; Arrhythmias, Cardiac; Benzothiadiazines; C

1975
Stable angina pectoris: 3. Medical treatment.
    Mayo Clinic proceedings, 1990, Volume: 65, Issue:2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Cardi

1990
Transdermal nitroglycerin (glyceryl trinitrate). A review of its pharmacology and therapeutic use.
    Drugs, 1990, Volume: 40, Issue:6

    Topics: Administration, Cutaneous; Angina Pectoris; Cardiovascular Diseases; Humans; Nitroglycerin

1990
Work environment and cardiovascular diseases. A short review of the literature.
    Journal of UOEH, 1989, Mar-20, Volume: 11 Suppl

    Topics: Cadmium; Carbon Disulfide; Cardiovascular Diseases; Cold Temperature; Electromagnetic Fields; Enviro

1989
Evaluation of effects of nitroglycerin therapy by echocardiography.
    Acta pharmacologica et toxicologica, 1986, Volume: 59 Suppl 6

    Topics: Cardiovascular Diseases; Echocardiography; Humans; Nitroglycerin

1986
Nitrates.
    The Medical clinics of North America, 1988, Volume: 72, Issue:1

    Topics: Animals; Cardiovascular Diseases; Coronary Disease; Heart Failure; Humans; Nitrates; Nitroglycerin

1988
Cutaneous reactions to cardiovascular drugs.
    The British journal of dermatology, 1973, Volume: 88, Issue:3

    Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Debrisoquin; Digitalis Glycosides;

1973

Trials

21 trials available for nitroglycerin and Cardiovascular Diseases

ArticleYear
Effect of Metformin on Vascular Function in Children With Type 1 Diabetes: A 12-Month Randomized Controlled Trial.
    The Journal of clinical endocrinology and metabolism, 2017, 12-01, Volume: 102, Issue:12

    Topics: Adolescent; Blood Vessels; Brachial Artery; Cardiovascular Diseases; Child; Diabetes Mellitus, Type

2017
The effect of continuous positive airway pressure therapy on arterial stiffness and endothelial function in obstructive sleep apnea: a randomized controlled trial in patients without cardiovascular disease.
    Sleep medicine, 2013, Volume: 14, Issue:12

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Aorta; Blood Flow Velocity; Cardiovascular Di

2013
Influence of Nitroglycerin on Coronary Artery CT Imaging in Cardiovascular Diseases.
    Cell biochemistry and biophysics, 2015, Volume: 72, Issue:2

    Topics: Adult; Aged; Cardiovascular Diseases; Coronary Angiography; Coronary Vessels; Female; Humans; Male;

2015
Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Cardiovascular Diseases; Case-Control Stud

2010
Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2010, Sep-03, Volume: 12

    Topics: Adult; Aged; Asymptomatic Diseases; Brachial Artery; California; Cardiovascular Diseases; Continuous

2010
The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study.
    Arthritis research & therapy, 2011, Jun-21, Volume: 13, Issue:3

    Topics: Acetylcholine; Adult; Aged; Arthritis, Rheumatoid; Cardiovascular Diseases; Cross-Sectional Studies;

2011
Nitroglycerin plus diltiazem versus nitroglycerin alone for spasm prophylaxis with transradial approach.
    The Journal of invasive cardiology, 2012, Volume: 24, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Pressure; Cardiovascular Diseases; Diltiazem; Drug Thera

2012
Flow-mediated vasodilation and anatomical variation of the brachial artery (double brachial artery) in healthy subjects and patients with cardiovascular disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:4

    Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Female; Humans; Male; Mi

2013
Evidence that cranberry juice may improve augmentation index in overweight men.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:1

    Topics: Adult; Albuterol; Beverages; Blood Pressure; Cardiovascular Diseases; Cardiovascular Physiological P

2013
Transdermal versus oral estrogen therapy in postmenopausal smokers: hemodynamic and endothelial effects.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Blood Pressure; Brachial Artery; Cardi

2004
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:4

    Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; En

2005
Different effect of hormone replacement therapy, DHEAS and tibolone on endothelial function in postmenopausal women with increased cardiovascular risk.
    Maturitas, 2005, Apr-11, Volume: 50, Issue:4

    Topics: Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind M

2005
Changes in the numeric descriptive scale for pain after sublingual nitroglycerin do not predict cardiac etiology of chest pain.
    Annals of emergency medicine, 2005, Volume: 45, Issue:6

    Topics: Administration, Sublingual; Cardiovascular Diseases; Chest Pain; Electrocardiography; Female; Humans

2005
Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects.
    Kidney international, 2006, Volume: 69, Issue:4

    Topics: Adult; Anemia, Iron-Deficiency; Brachial Artery; Cardiovascular Diseases; Chelating Agents; Double-B

2006
Effect of N-acetylcysteine on endothelial dysfunction in dialysis patients.
    Blood purification, 2007, Volume: 25, Issue:4

    Topics: Acetylcysteine; Adult; Antioxidants; Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular

2007
Effect of acute changes in oxygen tension on flow-mediated dilation. Relation to cardivascular risk.
    Scandinavian cardiovascular journal : SCJ, 2008, Volume: 42, Issue:1

    Topics: Administration, Inhalation; Adult; Atorvastatin; Brachial Artery; Cardiovascular Diseases; Cholester

2008
The effect of large unilamellar vesicles on vascular function in patients with coronary atherosclerosis.
    Atherosclerosis, 2008, Volume: 200, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cholesterol; Coronary Artery Disease; Endot

2008
Long-term association of brachial artery flow-mediated vasodilation and cardiovascular events in middle-aged subjects with no apparent heart disease.
    International journal of cardiology, 2009, May-01, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Diagnostic Tec

2009
Hemodynamic effects of bolus nicorandil compared with nitroglycerin.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:5

    Topics: Aged; Cardiovascular Diseases; Emergencies; Female; Hemodynamics; Humans; Male; Middle Aged; Niacina

1995
Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Blood Pressure; Cardiovascular Diseases; Endothelium, Vascular; Estrogen Replacement Therapy; Female

2001
A noninvasive method of predicting pulmonary-capillary wedge pressure.
    The New England journal of medicine, 1992, Dec-10, Volume: 327, Issue:24

    Topics: Blood Pressure; Cardiovascular Diseases; Hemodynamics; Humans; Methods; Nitroglycerin; Prospective S

1992

Other Studies

90 other studies available for nitroglycerin and Cardiovascular Diseases

ArticleYear
Effects of nitroglycerin-induced vasodilation on elastic and muscular artery stiffness in older Veterans.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:12

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Brachial Artery; Cardiovascular Diseases; Carotid Art

2022
Effect of menopause and age on vascular impairment.
    Maturitas, 2023, Volume: 169

    Topics: Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Hypoxia; Menopause;

2023
Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery.
    Journal of the American Heart Association, 2020, 01-21, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Endothelium, V

2020
Body mass index rather than the phenotype impacts precocious ultrasound cardiovascular risk markers in polycystic ovary syndrome.
    European journal of endocrinology, 2021, Volume: 184, Issue:1

    Topics: Adult; Body Mass Index; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cross-Sectional Stu

2021
Endothelium-Dependent and -Independent Vascular Function in Advanced Chronic Kidney Disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, Oct-06, Volume: 12, Issue:10

    Topics: Adult; Aged; Brachial Artery; Cardiovascular Diseases; Chi-Square Distribution; Cross-Sectional Stud

2017
Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors.
    Journal of the American Heart Association, 2017, 12-29, Volume: 7, Issue:1

    Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; F

2017
Serum cardiovascular risk biomarkers in pre-pubertal obese children.
    European journal of clinical investigation, 2018, Volume: 48, Issue:9

    Topics: Adiponectin; Behavior Therapy; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Ca

2018
Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Angiography; Atherosclerosis; Blo

2013
Impact of non-cardiovascular surgery on reactive hyperaemia and arterial endothelial function.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:7

    Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Blood Pressure; Brachial Artery; Cardiovascular Diseas

2013
Assessment of endothelial dysfunction by flow-mediated dilatation in men on long-term androgen deprivation therapy for prostate cancer.
    Experimental physiology, 2013, Volume: 98, Issue:9

    Topics: Aged; Androgen Antagonists; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Case-Cont

2013
The effects of hyperuricaemia on flow-mediated and nitroglycerin-mediated dilatation in high-risk patients.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; D

2014
Investigating the cardio-protective abilities of supplemental L-arginine on parameters of endothelial function in a hypercholesterolemic animal model.
    Journal of nutritional science and vitaminology, 2014, Volume: 60, Issue:3

    Topics: Amidohydrolases; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Cardiotonic Agents; Ca

2014
The CHADS2 and CHA2DS2-VASc scores predict adverse vascular function, ischemic stroke and cardiovascular death in high-risk patients without atrial fibrillation: role of incorporating PR prolongation.
    Atherosclerosis, 2014, Volume: 237, Issue:2

    Topics: Aged; Atrial Fibrillation; Body Mass Index; Cardiovascular Diseases; Carotid Intima-Media Thickness;

2014
Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Adult; Aged; Atherosclerosis; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Cohort

2016
Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events and restenosis in patients undergoing coronary stent implantation: a prospective study.
    Coronary artery disease, 2008, Volume: 19, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases;

2008
Vascular reactivity in patients with undifferentiated connective tissue diseases.
    Atherosclerosis, 2009, Volume: 203, Issue:1

    Topics: Acetylcholine; Adult; Brachial Artery; Cardiovascular Diseases; Case-Control Studies; Connective Tis

2009
Clinical usefulness of wave intensity analysis.
    Medical & biological engineering & computing, 2009, Volume: 47, Issue:2

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Echocardiogra

2009
Nitroglycerin-mediated S-nitrosylation of proteins: a field comes full cycle.
    Circulation research, 2008, Sep-12, Volume: 103, Issue:6

    Topics: Animals; Cardiovascular Diseases; Humans; Microcirculation; Nitroglycerin; Nitroso Compounds; Protei

2008
Percutaneous nitroglycerin treatment in cases of peripheral circulatory disorders, especially Raynaud's disease.
    Acta medica Scandinavica, 1948, Volume: 131, Issue:Suppl 206

    Topics: Administration, Cutaneous; Cardiovascular Diseases; Humans; Nitroglycerin; Raynaud Disease

1948
Inflammatory and thrombotic processes are associated with vascular dysfunction in children with familial hypercholesterolemia.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Adolescent; Age Factors; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studi

2009
High prevalence of subclinical cardiovascular abnormalities in patients with systemic lupus erythematosus in spite of a very low clinical damage index.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aortic Valve Insufficiency; Brachial Artery; Cardiovascular Diseases; Carotid Art

2009
Impaired endothelial function in hypertensive patients with target organ damage.
    Journal of human hypertension, 2009, Volume: 23, Issue:11

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Brachial Artery; Card

2009
Intima media thickness and endothelial function in chronic hemodialysis patients.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2009, Volume: 13, Issue:4

    Topics: Adult; Age Factors; Brachial Artery; Cardiovascular Diseases; Carotid Arteries; Diabetes Mellitus; E

2009
The relationship between cardiovascular risk estimated by use of SCORE system and intima media thickness and flow mediated dilatation in a low risk population.
    Cardiology journal, 2009, Volume: 16, Issue:5

    Topics: Adult; Age Factors; Brachial Artery; Cardiovascular Diseases; Carotid Artery, Common; Endothelium, V

2009
Enjoying hobbies is related to desirable cardiovascular effects.
    Heart and vessels, 2010, Volume: 25, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Coronary Angiogr

2010
Nitroglycerin-mediated vasodilatation of the brachial artery may predict long-term cardiovascular events irrespective of the presence of atherosclerotic disease.
    Journal of atherosclerosis and thrombosis, 2010, Dec-26, Volume: 17, Issue:12

    Topics: Aged; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Humans; Kinetics; Middle Aged; Nitr

2010
Impaired flow-mediated dilatation response in uncomplicated Type 1 diabetes mellitus: influence of shear stress and microvascular reactivity.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Diabetes

2011
Impaired flow-mediated dilatation response in uncomplicated Type 1 diabetes mellitus: influence of shear stress and microvascular reactivity.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Diabetes

2011
Impaired flow-mediated dilatation response in uncomplicated Type 1 diabetes mellitus: influence of shear stress and microvascular reactivity.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Diabetes

2011
Impaired flow-mediated dilatation response in uncomplicated Type 1 diabetes mellitus: influence of shear stress and microvascular reactivity.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Diabetes

2011
Non-dipping pattern relates to endothelial dysfunction in patients with uncontrolled resistant hypertension.
    Journal of human hypertension, 2011, Volume: 25, Issue:11

    Topics: Adult; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Amb

2011
Association between glycosylated haemoglobin A(1c) and endothelial function in an adult non-diabetic population.
    Atherosclerosis, 2011, Volume: 217, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biomarkers; Cardiovascular Diseases; Case-C

2011
Rho-associated kinase activity, endothelial function, and cardiovascular risk factors.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Blood Pressure; Blotting, Western; Body

2011
Association of testosterone levels with endothelial function in men: results from a population-based study.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; E

2012
Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation.
    Molecular pharmacology, 2012, Volume: 82, Issue:3

    Topics: Animals; Aorta; Biopterins; Cardiovascular Diseases; Cells, Cultured; Cyclic GMP; Endothelial Cells;

2012
Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Carotid A

2012
[Endothelial dysfunction and intima-media thickness in relation to cardiovascular risk factors in patients without clinical manifestations of atherosclerosis].
    Revista espanola de cardiologia, 2003, Volume: 56, Issue:6

    Topics: Aged; Arteriosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Male; Middle

2003
INTRACTABLE ANGINA.
    Progress in cardiovascular diseases, 1963, Volume: 6

    Topics: Anemia; Angina Pectoris; Anticoagulants; Anxiety; Cardiac Surgical Procedures; Cardiovascular Diseas

1963
MASQUERADES ENCOUNTERED IN THE DIFFERENTIAL DIAGNOSIS OF CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS.
    The American journal of gastroenterology, 1964, Volume: 42

    Topics: Angina Pectoris; Cardiovascular Diseases; Cholecystitis; Coronary Disease; Diagnosis, Differential;

1964
[Therapeutic compliance: new frontier in the efficiency of treatment. The example of nitroglycerin transdermal systems].
    Bollettino chimico farmaceutico, 2003, Volume: 142, Issue:5

    Topics: Cardiovascular Diseases; Humans; Nitroglycerin; Patient Compliance; Vasodilator Agents

2003
Therapy with nitrates: increasing evidence of vascular toxicity.
    Journal of the American College of Cardiology, 2003, Nov-19, Volume: 42, Issue:10

    Topics: Cardiovascular Diseases; Drug Tolerance; Endothelium, Vascular; Humans; Nitrates; Nitroglycerin; Rea

2003
The nitroglycerin-flicker test.
    Circulation, 1951, Volume: 4, Issue:3

    Topics: Cardiovascular Diseases; Diagnostic Techniques, Cardiovascular; Humans; Nitroglycerin

1951
Significance of the nitroglycerin-flicker fusion response in normal subjects and patients with cardiovascular disease.
    Circulation, 1951, Volume: 4, Issue:3

    Topics: Cardiovascular Diseases; Diagnostic Techniques, Cardiovascular; Flicker Fusion; Humans; Nitroglyceri

1951
The flicker fusion frequency and its response to nitroglycerin in normal subjects and in patients with cardiovascular disease.
    Circulation, 1952, Volume: 5, Issue:2

    Topics: Cardiovascular Diseases; Diagnostic Techniques, Cardiovascular; Flicker Fusion; Humans; Nitroglyceri

1952
Studies in the Arctic with the flicker-fusion nitroglycerin test; a new method of evaluating cardiovascular states.
    The New England journal of medicine, 1952, Mar-13, Volume: 246, Issue:11

    Topics: Cardiovascular Diseases; Diagnostic Techniques, Cardiovascular; Nitroglycerin; Vision, Ocular

1952
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
    Circulation, 2004, Feb-17, Volume: 109, Issue:6

    Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co

2004
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans.
    Circulation, 2004, Aug-31, Volume: 110, Issue:9

    Topics: Adult; Aged; Biomarkers; Brachial Artery; C-Reactive Protein; Cardiovascular Diseases; Endothelium,

2004
The response of the flicker fusion threshold to nitroglycerin and its potential value in the diagnosis, prognosis, and therapy of subclinical and clinical cardiovascular disease.
    Circulation, 1950, Volume: 1, Issue:6

    Topics: Cardiovascular Diseases; Flicker Fusion; Nitroglycerin; Prognosis; Vision, Ocular

1950
Benefit of glyceryl trinitrate on arterial stiffness is directly due to effects on peripheral arteries.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aorta; Blood Pressure; Cardiovascular Diseases; Compliance; Female;

2005
Cardiovascular risk factors in healthy women with previous gestational hypertension.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:4

    Topics: Adult; Blood Glucose; Body Composition; Brachial Artery; Carbohydrate Metabolism; Cardiovascular Dis

2006
Effect of pioglitazone on insulin sensitivity, vascular function and cardiovascular inflammatory markers in insulin-resistant non-diabetic Asian Indians.
    Diabetic medicine : a journal of the British Diabetic Association, 2006, Volume: 23, Issue:5

    Topics: Adipose Tissue; Administration, Sublingual; Adult; Aged; Biomarkers; Blood Glucose; Brachial Artery;

2006
Impaired vasoreactivity in bodybuilders using androgenic anabolic steroids.
    European journal of clinical investigation, 2006, Volume: 36, Issue:7

    Topics: Administration, Sublingual; Adult; Anabolic Agents; Androgens; Blood Pressure; Cardiovascular Diseas

2006
Glyceryl trinitrate (Anginine) use in a cardiovascular emergency.
    Contemporary nurse, 2006, Volume: 22, Issue:1

    Topics: Cardiovascular Diseases; Contraindications; Drug Tolerance; Humans; Nitroglycerin; Vasodilator Agent

2006
Insulin resistance, inflammation, and blood pressure determine vascular dysfunction in CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteries; Blood Pressure; Brachial Artery; Cardiovascula

2006
ESR techniques for the detection of nitric oxide in vivo as an index of endothelial function.
    Pharmacological reports : PR, 2006, Volume: 58 Suppl

    Topics: Adrenergic beta-Antagonists; Animals; Aorta; Carbazoles; Cardiovascular Diseases; Carvedilol; Cattle

2006
The association of endothelial dysfunction and cardiovascular events in healthy subjects and patients with cardiovascular disease.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brachial Artery; Cardiovascular Diseases; Echocardiograp

2007
Venous or arterial endothelium evaluation for early cardiovascular dysfunction in hypertensive patients?
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:11

    Topics: Acetylcholine; Adult; Arteries; Blood Glucose; Brachial Artery; Cardiovascular Diseases; Cardiovascu

2007
Cross-sectional study of endothelial function in HIV-infected patients in Brazil.
    AIDS research and human retroviruses, 2008, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Body Mass Index; Brachial Artery; Brazil; Cardiovascular Disease

2008
[Vasodilator therapy in cardiology].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Amyl Nitrite; Angina Pectoris; Cardiovascular Diseases; Coronary Disease; Heart Failure; Hemodynamic

1980
Transdermal absorption of nitroglycerin from microseal drug delivery (MDD) system.
    Angiology, 1983, Volume: 34, Issue:1

    Topics: Administration, Topical; Biological Availability; Cardiovascular Diseases; Delayed-Action Preparatio

1983
A profile of intravenous nitroglycerin use in cardiopulmonary bypass surgery.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:2

    Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiovascular Diseases; Coronary Disease; Fema

1983
Intravenous nitroglycerin: new uses for an old drug.
    Journal of the Iowa Medical Society, 1983, Volume: 73, Issue:3

    Topics: Cardiovascular Diseases; Cardiovascular System; Hemodynamics; Humans; Infusions, Parenteral; Nitrogl

1983
Mortality from cardio-cerebrovascular diseases among dynamite workers--an extended case-referent study.
    Annals of the Academy of Medicine, Singapore, 1984, Volume: 13, Issue:2 Suppl

    Topics: Adult; Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Humans; Male; Middle Aged; Nitrogly

1984
Pharmacology and electrophysiology of calcium ion antagonists.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Calcium; Cardiovascular Diseases; Gallopamil; Heart; Humans; Myocardial Contraction; Nitroglycerin;

1980
Pharmacologic intervention in cardiovascular nuclear medicine procedures.
    Seminars in nuclear medicine, 1981, Volume: 11, Issue:2

    Topics: Arteries; Blood Vessel Prosthesis; Cardiac Catheterization; Cardiovascular Diseases; Coronary Artery

1981
Nitroglycerin: using a familiar drug in new ways.
    The Canadian nurse, 1981, Volume: 77, Issue:8

    Topics: Cardiovascular Diseases; Humans; Nitroglycerin; Patient Education as Topic; Self Administration

1981
Drugs that alter nitric oxide homeostasis: a reply.
    Cardiovascular research, 1994, Volume: 28, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Humans; Nitric Oxide; Nitroglycer

1994
Validation of carotid artery tonometry as a means of estimating augmentation index of ascending aortic pressure.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Aorta, Thoracic; Blood Pressure; Cardiac Catheterization; Cardiomyopathy, H

1996
Guidelines for perioperative cardiovascular evaluation for noncardiac surgery. Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Perioperative Cardiovascular Evaluation for Noncardiac S
    Journal of the American College of Cardiology, 1996, Mar-15, Volume: 27, Issue:4

    Topics: Anesthesia; Angioplasty, Balloon, Coronary; Cardiology; Cardiovascular Diseases; Coronary Artery Byp

1996
Gender difference in improvement of endothelium-dependent vasodilation after estrogen supplementation.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:4

    Topics: Analysis of Variance; Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Estradiol; Fe

1997
Antiplasmin correlates to arterial reactivity in a healthy population of 35-year-old men and women.
    Journal of internal medicine, 1999, Volume: 245, Issue:1

    Topics: Adult; alpha-2-Antiplasmin; Antifibrinolytic Agents; Brachial Artery; Cardiovascular Diseases; Endot

1999
Endothelial dysfunction in hypopituitary adults with growth hormone deficiency.
    Clinical endocrinology, 1999, Volume: 50, Issue:4

    Topics: Adult; Blood Glucose; Brachial Artery; Cardiovascular Diseases; Case-Control Studies; Cholesterol, L

1999
Vascular function correlates with risk factors for cardiovascular disease in a healthy population of 35-year-old subjects.
    Journal of internal medicine, 1997, Volume: 241, Issue:6

    Topics: Adult; Blood Glucose; Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Female; Human

1997
Transoesophageal acoustic quantification for evaluation of cardiac function during laparoscopic surgery.
    Anaesthesia, 2001, Volume: 56, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Cardiovascular Diseases; Cholecystectomy, Laparoscop

2001
Gender difference in age-related changes in vascular function.
    Journal of internal medicine, 2001, Volume: 250, Issue:1

    Topics: Adult; Aging; Blood Cell Count; Blood Pressure; Body Mass Index; Brachial Artery; Cardiovascular Dis

2001
[Obstructive sleep apnea syndrome: a cardiovascular risk factor?].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:8

    Topics: Bradykinin; Cardiovascular Diseases; Data Interpretation, Statistical; Endothelium, Vascular; Follow

2001
Endothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivo.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Adult; Anatomy, Cross-Sectional; Arteries; Blood Pressure; Brachial Artery; Cardiovascular Diseases;

2001
Impaired vascular reactivity is present despite normal levels of von Willebrand factor in patients with uncomplicated Type 2 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:6

    Topics: Albuminuria; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Cholesterol; Diabetes Mellitu

2002
The problems of patients with cardiovascular disease undergoing dental treatment.
    Journal of the American Dental Association (1939), 1977, Volume: 94, Issue:6

    Topics: Anesthesia, Dental; Anesthesia, General; Anesthetics, Local; Anti-Bacterial Agents; Anticoagulants;

1977
The army's view.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1977, Volume: 19, Issue:8

    Topics: Cardiovascular Diseases; Environmental Exposure; Ethics, Medical; Government Agencies; Nitroglycerin

1977
Usefulness of long-acting nitrates in cardiovascular disease.
    The American journal of medicine, 1978, Volume: 64, Issue:2

    Topics: Cardiovascular Diseases; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nit

1978
Surgical complications of significance in dental practice.
    Dental journal, 1975, Volume: 41, Issue:5

    Topics: Anesthesia, Dental; Anesthesia, Local; Angina Pectoris; Anticoagulants; Cardiovascular Diseases; Den

1975
A symposium: 3rd North American Conference on Nitroglycerin Therapy. White Sulphur Springs, West Virginia, May 9-12, 1991.
    The American journal of cardiology, 1992, Sep-24, Volume: 70, Issue:8

    Topics: Cardiovascular Diseases; Humans; Nitroglycerin

1992
Cardiovascular mortality among munitions workers exposed to nitroglycerin and dinitrotoluene.
    Scandinavian journal of work, environment & health, 1992, Volume: 18, Issue:1

    Topics: Adult; Cardiovascular Diseases; Cause of Death; Cerebrovascular Disorders; Cohort Studies; Coronary

1992
Nitrates.
    AACN clinical issues in critical care nursing, 1992, Volume: 3, Issue:2

    Topics: Cardiovascular Diseases; Coronary Disease; Drug Interactions; Hemodynamics; Humans; Isosorbide Dinit

1992
Historical aspects of nitrate therapy.
    Drugs, 1987, Volume: 33 Suppl 4

    Topics: Cardiovascular Diseases; History, 19th Century; History, 20th Century; Humans; Isosorbide Dinitrate;

1987
[Modification of hemodynamic changes by the heart rate following sublingual administration of nitroglycerin--echocardiographic study].
    Kokyu to junkan. Respiration & circulation, 1985, Volume: 33, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Pressure; Cardiac Output; Cardiovascular Diseas

1985
[Pharmacologic properties and indications of modern vasodilator agents. 2: Indications and side effects of vasodilator agents].
    Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:20

    Topics: Arterial Occlusive Diseases; Brain Ischemia; Cardiovascular Diseases; Coronary Disease; Drug Therapy

1985
[Directed measures of the ambulatory scope of improvement of stationary care from the viewpoint of a specialist for cardiovascular diseases].
    Zeitschrift fur arztliche Fortbildung, 1974, Apr-01, Volume: 68, Issue:7

    Topics: Adrenergic beta-Antagonists; Ambulatory Care; Cardiovascular Diseases; Coronary Disease; Heart Defec

1974
[Medicamentous prophylaxis of postoperative cardiovascular complications (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-06, Volume: 116, Issue:36

    Topics: Aged; Cardiovascular Diseases; Digitalis Glycosides; Dipyridamole; Female; Humans; Male; Middle Aged

1974
The mechanism of action of cardiovascular drugs and their clinical effectiveness.
    Japanese heart journal, 1966, Volume: 7, Issue:1

    Topics: Cardiovascular Diseases; Digitalis Glycosides; Humans; Nitroglycerin; Plants, Medicinal; Quinidine;

1966
[The experimental production of cardiovascular diseases in monkeys].
    Vestnik Akademii meditsinskikh nauk SSSR, 1966, Volume: 21, Issue:4

    Topics: Animals; Arteriosclerosis; Atropine; Cardiovascular Diseases; Cholesterol; Coronary Disease; Diet, A

1966
[Value of clinico-pharmaco-dynamic tests in phonomechanography].
    Marseille medical, 1968, Volume: 105, Issue:3

    Topics: Adolescent; Adult; Amyl Nitrite; Angiocardiography; Cardiovascular Diseases; Female; Humans; Kinetoc

1968