Page last updated: 2024-11-01

nitroglycerin and Cardiomegaly

nitroglycerin has been researched along with Cardiomegaly in 33 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Low-dose intravenous nitroglycerin infusion can be safely administered during acute myocardial infarction to unload the left ventricle and salvage ischemic myocardium and left ventricular geometry and function."8.78Intravenous nitroglycerin unloading in acute myocardial infarction. ( Jugdutt, BI, 1991)
"Low-dose intravenous nitroglycerin infusion can be safely administered during acute myocardial infarction to unload the left ventricle and salvage ischemic myocardium and left ventricular geometry and function."4.78Intravenous nitroglycerin unloading in acute myocardial infarction. ( Jugdutt, BI, 1991)
"Even though cardiac hypertrophy is viewed as a beneficial compensatory process that normalizes wall stress, the increased muscle mass carries with it the need of increased blood supply."1.27Effects of vasodilators on the coronary circulation in congestive heart failure. ( Burkart, F; Kiowski, W, 1988)
"In dogs with experimental cardiac hypertrophy in resting conditions, coronary blood flow and myocardial O2 consumption increased proportionately to the cardiac mass; coronary flow and O2 consumption per gram of myocardium, therefore, ranged within normal values."1.26Coronary blood flow and myocardial O2 consumption in hypertrophied cardiac muscle in dogs. ( Marchetti, GV; Merlo, L; Visioli, O, 1976)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199023 (69.70)18.7374
1990's8 (24.24)18.2507
2000's1 (3.03)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alogna, A1
Schwarzl, M1
Manninger, M1
Hamdani, N1
Zirngast, B1
Kloth, B1
Steendijk, P1
Verderber, J1
Zweiker, D1
Westermann, D1
Blankenberg, S1
Maechler, H1
Tschöpe, C1
Linke, WA1
Marsche, G1
Pieske, BM1
Post, H1
Laskey, WK3
Reichek, N3
St John Sutton, M2
Untereker, WJ2
Hirshfeld, JW3
Ruskoaho, H1
Bart, BIa1
Pashkova, TL1
Stepanov, NG1
Orlova, TV1
Kalmanova, EN1
Schad, N1
Nickel, O1
Marroni, BJ1
Bolte, HD1
Li, YM1
Steffes, M1
Donnelly, T1
Liu, C1
Fuh, H1
Basgen, J1
Bucala, R1
Vlassara, H1
Kojda, G1
Kottenberg, K1
Stasch, JP1
Schrör, K1
Noack, E1
Karvats'kiĭ, IM1
Lahodych, TS1
Shevchuk, VH1
Miyagishima, Y1
Marchetti, GV2
Merlo, L2
Visioli, O2
Gaasch, WH1
Levine, HJ1
Quinones, MA1
Alexander, JK1
Chandraratna, PA1
Langevin, E1
Langevin, J1
Berkson, DM1
Jugdutt, BI1
Sharaf el-Deane, MS1
Parker, BM1
Lee, RT1
Lord, CP1
Plappert, T1
Sutton, MS2
Cohen, A1
Raffoul, H1
Diebold, B1
Albo, C1
Chevalier, B1
Francillon, A1
Le Heuzey, JY1
Abastado, P1
Rozenstajn, L1
Valty, J1
Firth, BG1
Dunnmon, PM1
Labbe, T1
Laporte, T1
Douard, H1
Barat, JL1
Roudaut, R1
Broustet, JP1
Mukharliamov, NM1
Negresku, EV1
Sazonova, LN1
Men'shikov, MIu1
Baldenkov, GN1
Zeevi, GR1
Martin, JL1
Bradley, AB1
Baim, DS1
Kiowski, W1
Burkart, F1
Carson, RP1
Wilson, WS1
Nemiroff, MJ1
Weber, WJ1
Wartak, J1
Astorri, E1
Mavilla, V1
Bini, L1
Majorano, C1
Smithen, CS1
Bennett, D1
Hudson, RE1
Sowton, E1
Gordon, AL1
Inchiosa, MA1
Lehr, D1
Noseda, V1
Russek, HI1
Guy, CR1
Eliot, RS1

Reviews

8 reviews available for nitroglycerin and Cardiomegaly

ArticleYear
[Treatment of heart failure with vasodilators].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Captopril; Cardiomegaly; Cardiotonic Agents; Coronary Disease; Heart Failure; Heart Function Tests;

1980
Left ventricular compliance: mechanisms and clinical implications.
    The American journal of cardiology, 1976, Nov-04, Volume: 38, Issue:5

    Topics: Angina Pectoris; Aortic Valve Insufficiency; Blood Pressure; Cardiac Output; Cardiac Volume; Cardiom

1976
Intravenous nitroglycerin unloading in acute myocardial infarction.
    The American journal of cardiology, 1991, Nov-18, Volume: 68, Issue:14

    Topics: Animals; Cardiomegaly; Heart; Humans; Infusions, Intravenous; Myocardial Infarction; Nitroglycerin;

1991
Postinfarction cardiac dilatation. Is it modifiable?
    Chest, 1990, Volume: 97, Issue:2

    Topics: Animals; Captopril; Cardiomegaly; Humans; Myocardial Contraction; Myocardial Infarction; Nifedipine;

1990
[Dynamic left ventricular obstruction increased by nitroglycerin in elderly patients with hypertension and concentric left ventricular hypertrophy].
    Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8

    Topics: Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female; Heart Ventricles; Humans

1990
The prevention of congestive heart failure: left ventricular dilation and its management.
    The American journal of the medical sciences, 1990, Volume: 299, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Cardiomyopathy, Dilated; Dogs; Huma

1990
Measurement of coronary blood flow in man: methods and implications for clinical practice.
    Cardiovascular clinics, 1985, Volume: 15, Issue:1

    Topics: Amrinone; Angina Pectoris; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary V

1985
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
    Advances in cardiology, 1973, Volume: 9

    Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He

1973

Other Studies

25 other studies available for nitroglycerin and Cardiomegaly

ArticleYear
Acute stimulation of the soluble guanylate cyclase does not impact on left ventricular capacitance in normal and hypertrophied porcine hearts in vivo.
    American journal of physiology. Heart and circulatory physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Blood Pressure; Cardiomegaly; Connectin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases;

2018
Myocardial oxygen consumption in left ventricular hypertrophy and its relation to left ventricular mechanics.
    The American journal of cardiology, 1983, Oct-01, Volume: 52, Issue:7

    Topics: Adult; Aged; Cardiomegaly; Coronary Circulation; Female; Heart Ventricles; Humans; Male; Middle Aged

1983
Matching of myocardial oxygen consumption to mechanical load in human left ventricular hypertrophy and dysfunction.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:2 Pt 1

    Topics: Adult; Aged; Cardiac Catheterization; Cardiomegaly; Coronary Circulation; Echocardiography; Female;

1984
Prevention of cardiac hypertrophy by long-term treatment with isosorbide dinitrate and prazosin but not by minoxidil in spontaneously hypertensive rats.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:2

    Topics: Animals; Blood Pressure; Cardiomegaly; Female; Hypertension; Isosorbide Dinitrate; Male; Minoxidil;

1984
[Dilatation (congestive) cardiomyopathy: clinical aspects, diagnosis and treatment].
    Kardiologiia, 1984, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Cardiomegaly; Cardiomyopathy, Dilated; Coronary Disease; Diagnosis, Differential;

1984
[Radionuclide angiography of the left ventricle using the first-pass technic].
    Rontgenpraxis; Zeitschrift fur radiologische Technik, 1980, Volume: 33, Issue:6

    Topics: Cardiomegaly; Coronary Disease; Heart; Heart Ventricles; Humans; Methods; Myocardial Infarction; Nit

1980
Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-30, Volume: 93, Issue:9

    Topics: Acetylcholine; Aging; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; Creatinine; Enzyme

1996
Positive inotropic effect of exogenous and endogenous NO in hypertrophic rat hearts.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Animals; Blood Pressure; Cardiomegaly; Heart; Heart Rate; Hypertension; In Vitro Techniques; Male; M

1997
[Effect of nitric oxide on force-frequency relations in experimental hyperfunction and hypertrophy in the heart muscle].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2001, Volume: 47, Issue:3

    Topics: Action Potentials; Animals; Arginine; Caffeine; Cardiomegaly; Dose-Response Relationship, Drug; Elec

2001
[Catecholamine in the myocardium; a fluorescence histochemical study].
    Japanese circulation journal, 1975, Volume: 39, Issue:3

    Topics: Animals; Atrioventricular Node; Cardiomegaly; Catecholamines; Dogs; Heart Atria; Heart Block; Heart

1975
Coronary blood flow and myocardial O2 consumption in hypertrophied cardiac muscle in dogs.
    Advances in cardiology, 1976, Volume: 18, Issue:0

    Topics: Animals; Cardiac Output; Cardiomegaly; Coronary Circulation; Dipyridamole; Dogs; Myocardium; Nitrogl

1976
Pulsus alternans induced by glyceryl trinitrate paste in a patient with alcoholic cardiomyopathy.
    British heart journal, 1979, Volume: 41, Issue:3

    Topics: Adult; Blood Pressure; Cardiomegaly; Cardiomyopathy, Alcoholic; Heart Failure; Hepatitis, Alcoholic;

1979
Controlling ventricular dilation in the compromised myocardium.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Coronary

1992
Effects of nifedipine on transmitral Doppler blood flow velocity profile in patients with concentric left ventricular hypertrophy.
    American heart journal, 1990, Volume: 119, Issue:5

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiomegaly; Diastole; Echocardiography; Echocardiograp

1990
[Contribution of Doppler echocardiography and thallium in cases of major ST segment depression in athletes].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 2

    Topics: Cardiomegaly; Cardiomyopathies; Coronary Angiography; Echocardiography, Doppler; Electrocardiography

1989
[New approaches to the study of the mechanism of action of nitrates].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:8

    Topics: Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiomegaly; Ferricyanides; H

1988
Effects of nitroglycerin in patients with angina, normal coronary arteries, and left ventricular hypertrophy.
    American heart journal, 1986, Volume: 112, Issue:5

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Coronary Circulation; Heart Rate; Heart Ventricles; Human

1986
Effects of vasodilators on the coronary circulation in congestive heart failure.
    The American journal of cardiology, 1988, Sep-09, Volume: 62, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Cardiomegaly; Cilazapri

1988
The effects of sublingual nitroglycerin on myocardial blood flow in patients with coronary artery disease or myocardial hypertrophy.
    American heart journal, 1969, Volume: 77, Issue:5

    Topics: Angina Pectoris; Cardiac Catheterization; Cardiomegaly; Coronary Angiography; Coronary Disease; Coro

1969
ECG criteria for angina pectoris derived from resting frank lead electrocardiograms.
    Chest, 1970, Volume: 58, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Cardiomegaly; Computers; Diagnosis, Differential; Electrocardiography;

1970
[Effects of intravenous administration of phentolamine and nitroglycerin on the electrocardiographic tracings of left ventricular hypertrophy].
    Giornale di clinica medica, 1969, Volume: 50, Issue:7

    Topics: Adult; Aged; Cardiomegaly; Electrocardiography; Female; Heart; Heart Ventricles; Humans; Hypertensio

1969
Trifascicular block--an electrocardiographic, hemodynamic and pathological correlation.
    Journal of electrocardiology, 1971, Volume: 4, Issue:2

    Topics: Angina Pectoris; Atropine; Blood Pressure; Bradycardia; Bundle-Branch Block; Cardiac Catheterization

1971
Isoproterenol-induced cardiomegaly: assessment of myocardial protein content, actomyosin ATPase and heart rate.
    Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:6

    Topics: Actomyosin; Adenosine Triphosphatases; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal

1972
Myocardial blood flow in experimental cardiac hypertrophy in dogs.
    Cardiovascular research, 1973, Volume: 7, Issue:4

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Blood Pressure; Body Weight; Cardiomega

1973
The "natural" history of severe angina pectoris with intensive medical therapy alone: a five year prospective study of 133 patients.
    Chest, 1974, Volume: 65, Issue:1

    Topics: Adult; Aged; Aging; Angina Pectoris; Atrial Fibrillation; Cardiomegaly; Cerebrovascular Disorders; D

1974