nitroglycerin has been researched along with Breast Cancer in 16 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There was an overall 22 percent decreased incidence of mastectomy flap necrosis in the nitroglycerin ointment cohort (47." | 9.27 | Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction. ( Fine, N; Li, DD; Turin, SY; Vaca, EE, 2018) |
| "In patients undergoing mastectomy and immediate reconstruction, there was a marked reduction in mastectomy flap necrosis in patients who received nitroglycerin ointment." | 9.20 | Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial. ( Bahng, S; Bovill, E; Brasher, P; Gdalevitch, P; Ho, A; Lennox, P; Macadam, S; Van Laeken, N, 2015) |
| "Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it." | 9.05 | Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis. ( Gu, L; Ma, J; Qin, Z; Wang, P; Wang, Q, 2020) |
| "There was an overall 22 percent decreased incidence of mastectomy flap necrosis in the nitroglycerin ointment cohort (47." | 5.27 | Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction. ( Fine, N; Li, DD; Turin, SY; Vaca, EE, 2018) |
| "In patients undergoing mastectomy and immediate reconstruction, there was a marked reduction in mastectomy flap necrosis in patients who received nitroglycerin ointment." | 5.20 | Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial. ( Bahng, S; Bovill, E; Brasher, P; Gdalevitch, P; Ho, A; Lennox, P; Macadam, S; Van Laeken, N, 2015) |
| "Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it." | 5.05 | Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis. ( Gu, L; Ma, J; Qin, Z; Wang, P; Wang, Q, 2020) |
| "Survival of human prostate and breast cancer cells was assessed by clonogenic assays following exposure to chemotherapeutic agents." | 1.34 | Chemosensitization of cancer in vitro and in vivo by nitric oxide signaling. ( Adams, MA; Bennett, BM; Frederiksen, LJ; Graham, CH; Macdonald-Goodfellow, SK; Maxwell, LR; Siemens, DR; Sullivan, R, 2007) |
| "The potential for malignancy detection using dynamic infrared imaging (DIRI) has been investigated in an animal model of human malignancy." | 1.32 | Dynamic infrared imaging for the detection of malignancy. ( Button, TM; Carvelli, P; Dulaimy, K; Fisher, P; Geronimo, C; Geronimo, V; Jambawalikar, S; Li, H; Li, S; O'Hea, B; Rosenblatt, R; Salvitti, M; Weiss, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Yao, A | 1 |
| Greige, N | 1 |
| Ricci, JA | 1 |
| Draper, LB | 1 |
| Weichman, KE | 1 |
| Wang, P | 1 |
| Gu, L | 1 |
| Qin, Z | 1 |
| Wang, Q | 1 |
| Ma, J | 1 |
| Turin, SY | 1 |
| Li, DD | 1 |
| Vaca, EE | 1 |
| Fine, N | 1 |
| Luce, EA | 1 |
| Gdalevitch, P | 2 |
| Van Laeken, N | 1 |
| Bahng, S | 1 |
| Ho, A | 1 |
| Bovill, E | 1 |
| Lennox, P | 1 |
| Brasher, P | 2 |
| Macadam, S | 2 |
| Hwang, K | 1 |
| Le Brun-Ly, V | 1 |
| Martin, J | 1 |
| Venat-Bouvet, L | 1 |
| Darodes, N | 1 |
| Labourey, JL | 1 |
| Genet, D | 1 |
| Tubiana-Mathieu, N | 1 |
| Kutun, S | 1 |
| Ay, AA | 1 |
| Ulucanlar, H | 1 |
| Tarcan, O | 1 |
| Ay, A | 1 |
| Aldan, M | 1 |
| Gorkem, G | 1 |
| Demir, A | 1 |
| Cetin, A | 1 |
| Buccimazza, I | 1 |
| Brakovsky, Y | 1 |
| Szabolcsi, O | 1 |
| Nagy-Toldi, A | 1 |
| Zeher, M | 1 |
| Végh, J | 1 |
| Button, TM | 1 |
| Li, H | 1 |
| Fisher, P | 1 |
| Rosenblatt, R | 1 |
| Dulaimy, K | 1 |
| Li, S | 1 |
| O'Hea, B | 1 |
| Salvitti, M | 1 |
| Geronimo, V | 1 |
| Geronimo, C | 1 |
| Jambawalikar, S | 1 |
| Carvelli, P | 1 |
| Weiss, R | 1 |
| Frederiksen, LJ | 1 |
| Sullivan, R | 1 |
| Maxwell, LR | 1 |
| Macdonald-Goodfellow, SK | 1 |
| Adams, MA | 1 |
| Bennett, BM | 1 |
| Siemens, DR | 1 |
| Graham, CH | 1 |
| Schmitt, R | 1 |
| Helmberger, T | 1 |
| Fellner, F | 1 |
| Obletter, N | 1 |
| Fan, Z | 1 |
| He, J | 1 |
| Adami, A | 1 |
| Crivellente, F | 1 |
| De Prati, AC | 1 |
| Cavalieri, E | 1 |
| Cuzzolin, L | 1 |
| Tommasi, M | 1 |
| Suzuki, H | 1 |
| Benoni, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Nitroglycerin Ointment on Mastectomy Flap Necrosis[NCT01608880] | 154 participants (Actual) | Interventional | 2012-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Breast Cancer
| Article | Year |
|---|---|
Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis.
Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mammary Glands, Human; Mastectomy; Middle Aged; Necro | 2020 |
3 trials available for nitroglycerin and Breast Cancer
| Article | Year |
|---|---|
Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction.
Topics: Administration, Cutaneous; Adult; Breast; Breast Implantation; Breast Neoplasms; Female; Follow-Up S | 2018 |
Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial.
Topics: Administration, Topical; Adult; Aged; Breast Neoplasms; British Columbia; Female; Follow-Up Studies; | 2015 |
Is transdermal nitroglycerin application effective in preventing and healing flap ischaemia after modified radical mastectomy?
Topics: Administration, Topical; Adult; Breast Neoplasms; Chi-Square Distribution; Female; Humans; Ischemia; | 2010 |
12 other studies available for nitroglycerin and Breast Cancer
| Article | Year |
|---|---|
Topical Nitroglycerin Ointment Reduces Mastectomy Flap Necrosis in Immediate Autologous Breast Reconstruction.
Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mastectomy; Necrosis; Nitroglycerin; Ointments; Posto | 2023 |
Discussion: Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction.
Topics: Breast Implants; Breast Neoplasms; Humans; Mammaplasty; Mastectomy; Nitroglycerin; Postoperative Com | 2018 |
Effects of Nitroglycerin Ointment on Mastectomy Flap Necrosis in Immediate Breast Reconstruction: A Randomized Controlled Trial.
Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mastectomy; Nitroglycerin; Surgical Flaps | 2016 |
Reply: Effects of Nitroglycerin Ointment on Mastectomy Flap Necrosis in Immediate Breast Reconstruction: A Randomized Controlled Trial.
Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mastectomy; Nitroglycerin; Surgical Flaps | 2016 |
Cardiac toxicity with capecitabine, vinorelbine and trastuzumab therapy: case report and review of fluoropyrimidine-related cardiotoxicity.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera | 2009 |
Is transdermal nitroglycerin application effective in preventing and healing flap ischaemia after modified radical mastectomy?
Topics: Breast Neoplasms; Female; Humans; Ischemia; Nitroglycerin; Postoperative Complications; Surgical Fla | 2011 |
[Systemic sclerosis in a patient suffering from breast cancer].
Topics: Adult; Amlodipine; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Duct | 2012 |
Dynamic infrared imaging for the detection of malignancy.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Humans; Image Processing, Compu | 2004 |
Chemosensitization of cancer in vitro and in vivo by nitric oxide signaling.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cyclic GMP; Drug R | 2007 |
[The marking of nonpalpable breast tumors in MRT].
Topics: Biopsy; Breast; Breast Neoplasms; Capsules; Contrast Media; Female; Gadolinium; Gadolinium DTPA; Hum | 1993 |
Preventing necrosis of the skin flaps with nitroglycerin after radical resection for breast cancer.
Topics: Breast Neoplasms; Female; Humans; Mastectomy, Radical; Necrosis; Nitroglycerin; Surgical Flaps | 1993 |
Biotransformation and cytotoxic properties of NO-donors on MCF7 and U251 cell lines.
Topics: Biotransformation; Brain Neoplasms; Breast Neoplasms; Cell Survival; Enzyme Inhibitors; Female; Glio | 1998 |