Page last updated: 2024-11-01

nitroglycerin and Brain Neoplasms

nitroglycerin has been researched along with Brain Neoplasms in 6 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"Nitroglycerin was given intravenously to five anesthetized, hyperventilated (PaCO2 25 to 30 torr) patients during craniotomy, to facilitate surgery by creating a relatively bloodless field, and to decrease the potential need to blood transfusion."1.26Intracranial pressure during nitroglycerin-induced hypotension. ( Cottrell, JE; Flamm, ES; Gupta, B; Ransohoff, J; Rappaport, H; Turndorf, H, 1980)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Arrieta, O1
Hernández-Pedro, N1
Maldonado, F1
Ramos-Ramírez, M1
Yamamoto-Ramos, M1
López-Macías, D1
Lozano, F1
Zatarain-Barrón, ZL1
Turcott, JG1
Barrios-Bernal, P1
Orozco-Morales, M1
Flores-Estrada, D1
Cardona, AF1
Rolfo, C1
Cacho-Díaz, B1
Cottrell, JE1
Gupta, B1
Rappaport, H1
Turndorf, H1
Ransohoff, J1
Flamm, ES1
Adami, A1
Crivellente, F1
De Prati, AC1
Cavalieri, E1
Cuzzolin, L1
Tommasi, M1
Suzuki, H1
Benoni, G1
Kazanskiĭ, IaF1
Borovikova, VN1
Fasano, VA1
Urciuoli, R1
Bolognese, P1
Mostert, M1
Hadjiev, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nitroglycerin Plus Whole Intracranial Radiotherapy for Brain Metastases in Non-small Cell Lung Cancer Patients: a Phase II Open Randomized Clinical Trial[NCT04338867]Phase 296 participants (Actual)Interventional2020-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitroglycerin and Brain Neoplasms

ArticleYear
Impedance methods for investigation of cerebral circulation.
    Progress in brain research, 1972, Volume: 35

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carbon Dioxide; Carotid Artery Diseases; Cerebral

1972

Trials

1 trial available for nitroglycerin and Brain Neoplasms

ArticleYear
Nitroglycerin Plus Whole Intracranial Radiation Therapy for Brain Metastases in Patients With Non-Small Cell Lung Cancer: A Randomized, Open-Label, Phase 2 Clinical Trial.
    International journal of radiation oncology, biology, physics, 2023, 03-01, Volume: 115, Issue:3

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cranial Irradiation; Humans; Lung Neoplasms; Nitrog

2023

Other Studies

4 other studies available for nitroglycerin and Brain Neoplasms

ArticleYear
Intracranial pressure during nitroglycerin-induced hypotension.
    Journal of neurosurgery, 1980, Volume: 53, Issue:3

    Topics: Adult; Blood Pressure; Brain Neoplasms; Humans; Hypotension, Controlled; Intracranial Arteriovenous

1980
Biotransformation and cytotoxic properties of NO-donors on MCF7 and U251 cell lines.
    Life sciences, 1998, Volume: 63, Issue:23

    Topics: Biotransformation; Brain Neoplasms; Breast Neoplasms; Cell Survival; Enzyme Inhibitors; Female; Glio

1998
[Controlled arterial hypotension using nitroglycerin in the complex anesthesiological support during operations on patients with brain tumors].
    Sovetskaia meditsina, 1991, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Brain Neoplasms; Cerebrovascular Circulation; Hemodyna

1991
Intraoperative use of laser Doppler in the study of cerebral microvascular circulation.
    Acta neurochirurgica, 1988, Volume: 95, Issue:1-2

    Topics: Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; M

1988