nitroglycerin has been researched along with Autonomic Dysreflexia in 4 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Autonomic Dysreflexia: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitroglycerin ointment has a rapid onset of action and time to full clinical effect with high efficacy and relatively low adverse event rate for patients with SCI experiencing AD." | 5.46 | Pharmacodynamics and effectiveness of topical nitroglycerin at lowering blood pressure during autonomic dysreflexia. ( Bunnell, AE; Burns, SP; Engle, A; Linsenmeyer, TA; Solinsky, R; Svircev, JN, 2017) |
| "This inpatient nursing driven-protocol for treating autonomic dysreflexia utilizing conservative measures, nitroglycerin paste and oral hydralazine achieved target blood pressure with a high success rate and a low incidence of adverse events." | 3.83 | A retrospective review of safety using a nursing driven protocol for autonomic dysreflexia in patients with spinal cord injuries. ( Bunnell, AE; Burns, SP; James, JJ; Solinsky, R; Svircev, JN, 2016) |
| "Nitroglycerin ointment has a rapid onset of action and time to full clinical effect with high efficacy and relatively low adverse event rate for patients with SCI experiencing AD." | 1.46 | Pharmacodynamics and effectiveness of topical nitroglycerin at lowering blood pressure during autonomic dysreflexia. ( Bunnell, AE; Burns, SP; Engle, A; Linsenmeyer, TA; Solinsky, R; Svircev, JN, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinsky, R | 3 |
| Bunnell, AE | 2 |
| Linsenmeyer, TA | 1 |
| Svircev, JN | 2 |
| Engle, A | 1 |
| Burns, SP | 3 |
| Kirshblum, SC | 1 |
| James, JJ | 1 |
| Baron, EL | 1 |
| Frost, EAM | 1 |
| Bonilla, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388] | 46 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for nitroglycerin and Autonomic Dysreflexia
| Article | Year |
|---|---|
Pharmacodynamics and effectiveness of topical nitroglycerin at lowering blood pressure during autonomic dysreflexia.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Autonomic Dysreflexia; Blood Pressure; Hosp | 2017 |
Exploring detailed characteristics of autonomic dysreflexia.
Topics: Antihypertensive Agents; Autonomic Dysreflexia; Blood Pressure; Humans; Male; Middle Aged; Nitroglyc | 2018 |
A retrospective review of safety using a nursing driven protocol for autonomic dysreflexia in patients with spinal cord injuries.
Topics: Adult; Aged; Aged, 80 and over; Autonomic Dysreflexia; Guideline Adherence; Humans; Hydralazine; Mal | 2016 |
Unusual Presentation of Refractory Autonomic Dysreflexia During General Anesthesia.
Topics: Anesthesia, General; Autonomic Dysreflexia; Blood Pressure; Humans; Male; Middle Aged; Nitroglycerin | 2017 |