nitroglycerin has been researched along with Atypical Cluster Headache in 31 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the central processing of cluster headache (CH) attacks provoked by sublingual nitroglycerin (NTG)." | 7.69 | Right-lateralised central processing for pain of nitroglycerin-induced cluster headache. ( Hannerz, J; Hsieh, JC; Ingvar, M, 1996) |
| "Eight patients with episodic cluster headache, five in active episode, three out of episode, were investigated as to diameters of intracranial arteries before and after nitroglycerin (NG) administration." | 7.68 | MRI of intracranial arteries in nitroglycerin induced cluster headache attacks. ( Greitz, D; Hannerz, J, 1992) |
| "Eighteen cluster headache patients and five controls were studied using ultrasound duplex techniques to measure blood flow in the common carotid arteries after nitroglycerin and placebo administration." | 5.07 | Pain induces decrease of blood flow in the common carotid arteries in cluster headache attacks. ( Hannerz, J; Jogestrand, T, 1993) |
| " We have investigated the central processing of cluster headache (CH) attacks provoked by sublingual nitroglycerin (NTG)." | 3.69 | Right-lateralised central processing for pain of nitroglycerin-induced cluster headache. ( Hannerz, J; Hsieh, JC; Ingvar, M, 1996) |
| "Six patients with episodic cluster headache were investigated as to blood pressure, heart rate, cerebrospinal fluid pressure (Pcsf) and frontal vein pressure (Pvf) during five nitroglycerin (NG) provoked attacks and one spontaneous attack." | 3.68 | Cerebrospinal fluid pressure and venous pressure in "dynamite headache" and cluster headache attacks. ( Greitz, D; Hannerz, J, 1992) |
| "Eight patients with episodic cluster headache, five in active episode, three out of episode, were investigated as to diameters of intracranial arteries before and after nitroglycerin (NG) administration." | 3.68 | MRI of intracranial arteries in nitroglycerin induced cluster headache attacks. ( Greitz, D; Hannerz, J, 1992) |
| "Our data demonstrate that severe cluster headache leads to significant increases in regional cerebral perfusion, likely to reflect changes in neuronal activity in several regions of the brain, including the hypothalamus and the ventral pons." | 3.11 | Areas of cerebral blood flow changes on arterial spin labelling with the use of symmetric template during nitroglycerin triggered cluster headache attacks. ( Goadsby, PJ; O'Daly, O; Wei, DY; Zelaya, FO, 2022) |
| "The pain is associated with ipsilateral autonomic symptoms (most commonly lacrimation, conjunctival injection, nasal congestion or rhinorrhea, ptosis, edema of the eyelid, sweating of the forehead or face, and miosis) and a sense of agitation or restlessness." | 2.82 | Cluster Headache: Rapid Evidence Review. ( Bailey, J; Hawks, MK; Malu, OO, 2022) |
| "Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related peptide (CGRP) and response to triptans and neuromodulation." | 2.58 | Migraine and cluster headache - the common link. ( Ashina, M; Benemei, S; Cortese, F; Labastida-Ramírez, A; Lampl, C; Marchese, F; Pellesi, L; Romoli, M; Vollesen, AL, 2018) |
| "Thirty-three subjects with cluster headache were included in the study; 24 completed all three study visits." | 1.62 | Comprehensive clinical phenotyping of nitroglycerin infusion induced cluster headache attacks. ( Goadsby, PJ; Wei, DY, 2021) |
| "Nitroglycerin-induced migraine-like headache has been used as an experimental model of migraine." | 1.32 | Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches. ( Ghiotto, N; Nappi, G; Pucci, E; Sances, G; Sandrini, G; Tassorelli, C, 2004) |
| "We assessed a patient with cluster headache and migraine by positron emission tomography during an active cluster headache after he had taken 1." | 1.31 | Brainstem activation specific to migraine headache. ( Bahra, A; Buchel, C; Frackowiak, RS; Goadsby, PJ; Matharu, MS, 2001) |
| "Nineteen subjects suffering from episodic cluster headache participated in the study." | 1.30 | Responsiveness of the trigeminovascular system to nitroglycerine in cluster headache patients. ( Alessandri, M; Fanciullacci, M; Marabini, S; Sicuteri, R, 1997) |
| "In seven cluster headache patients in whom nitroglycerin did not cause an attack, only an initial peak in MSA occurred." | 1.30 | Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks. ( Fagius, J; Nordin, M; Waldenlind, E, 1997) |
| "Eight patients who had cluster headache but were not in the bout acted as a control group." | 1.30 | Hypothalamic activation in cluster headache attacks. ( Bahra, A; Büchel, C; Frackowiak, RS; Goadsby, PJ; May, A, 1998) |
| "Nine patients with chronic cluster headache were studied as to end-tidal PCO2, heart rate, blood pressure, common carotid artery blood flow, vascular resistance, and intensity and duration of pain before, during, and after breathing 6% CO2 in air for 6 minutes and before and after administration of 1 mg nitroglycerin sublingually." | 1.29 | Chronic cluster headache: provocation with carbon dioxide breathing and nitroglycerin. ( Hannerz, J; Jogestrand, T, 1996) |
| "Nitroglycerin (NG) induces in cluster headache patients and controls an increase in systemic diastolic blood pressure and/or heart rate and a decrease in blood flow velocity in the middle cerebral artery (VMCA)." | 1.28 | Cluster headache and "dynamite headache": blood flow velocities in the middle cerebral artery. ( Hannerz, J; Hellström, G; Klum, T; Wahlgren, NG, 1990) |
| "Attacks of cluster headache provoked by the administration of nitroglycerin (1 mg sublingually) or histamine (0." | 1.28 | Studies on nitroglycerin and histamine provoked cluster headache attacks. ( Bogucki, A, 1990) |
| "Ten episodic cluster headache patients in their active cluster period, ten patients in remission and five control subjects were monitored for minute to minute changes in oxygen saturation (SaO2) and pulse rate before and after nitroglycerin (NTG) administration." | 1.28 | Association of sustained oxyhemoglobin desaturation and onset of cluster headache attacks. ( Kudrow, DB; Kudrow, L, 1990) |
| "15 chronic cluster headache patients in whom pain was induced by nitroglycerin received acute intravenous treatment with a calcium entry blocker." | 1.27 | Calcium entry blocker: treatment in acute pain in cluster headache patients. ( Boiardi, A; Bussone, G; Gemma, M; Peccarisi, C; Porta, E, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 15 (48.39) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, DY | 2 |
| O'Daly, O | 1 |
| Zelaya, FO | 1 |
| Goadsby, PJ | 4 |
| Malu, OO | 1 |
| Bailey, J | 1 |
| Hawks, MK | 1 |
| Vollesen, AL | 1 |
| Benemei, S | 1 |
| Cortese, F | 1 |
| Labastida-Ramírez, A | 1 |
| Marchese, F | 1 |
| Pellesi, L | 1 |
| Romoli, M | 1 |
| Ashina, M | 1 |
| Lampl, C | 1 |
| Costa, A | 2 |
| Ravaglia, S | 1 |
| Sances, G | 3 |
| Antonaci, F | 3 |
| Pucci, E | 3 |
| Nappi, G | 4 |
| Tassorelli, C | 2 |
| Ghiotto, N | 1 |
| Sandrini, G | 2 |
| Schoenen, J | 1 |
| Di Clemente, L | 1 |
| Vandenheede, M | 1 |
| Fumal, A | 1 |
| De Pasqua, V | 1 |
| Mouchamps, M | 1 |
| Remacle, JM | 1 |
| de Noordhout, AM | 1 |
| Olesen, J | 2 |
| Krabbe, AA | 1 |
| Henriksen, L | 1 |
| Nattero, G | 1 |
| Fanciullacci, M | 2 |
| Alessandri, M | 2 |
| Figini, M | 1 |
| Geppetti, P | 1 |
| Michelacci, S | 1 |
| Khurana, RK | 1 |
| Hannerz, J | 6 |
| Jogestrand, T | 2 |
| Hsieh, JC | 1 |
| Ingvar, M | 1 |
| Sicuteri, R | 1 |
| Marabini, S | 1 |
| Nordin, M | 1 |
| Fagius, J | 1 |
| Waldenlind, E | 1 |
| May, A | 1 |
| Bahra, A | 2 |
| Büchel, C | 2 |
| Frackowiak, RS | 2 |
| Micieli, G | 1 |
| Granella, F | 1 |
| Broich, G | 1 |
| Matharu, MS | 1 |
| Greitz, D | 2 |
| Hellström, G | 1 |
| Klum, T | 1 |
| Wahlgren, NG | 1 |
| Bogucki, A | 1 |
| Dahl, A | 1 |
| Russell, D | 1 |
| Nyberg-Hansen, R | 1 |
| Rootwelt, K | 1 |
| Kudrow, L | 1 |
| Kudrow, DB | 1 |
| Jelencsik, I | 1 |
| Kovács, K | 1 |
| Csanda, E | 1 |
| Boiardi, A | 1 |
| Gemma, M | 1 |
| Porta, E | 1 |
| Peccarisi, C | 1 |
| Bussone, G | 1 |
| Drummond, PD | 1 |
| Anthony, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biomarker Identification to Predict the Evolution of Migraine From an Episodic to a Chronic Condition[NCT04696510] | 15 participants (Actual) | Observational | 2018-08-31 | Completed | |||
| Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack: a Cross-over, Randomized Controlled Study[NCT05718310] | 22 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches[NCT00391755] | Phase 4 | 4 participants (Actual) | Interventional | 2006-10-31 | Terminated (stopped due to Failure to recruit necessary number of patients.) | ||
| Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging[NCT01741246] | 78 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitroglycerin and Atypical Cluster Headache
| Article | Year |
|---|---|
Cluster Headache: Rapid Evidence Review.
Topics: Adult; Alcohol Drinking; Cluster Headache; Female; Humans; Male; Nitrates; Nitroglycerin; Oxygen; Pa | 2022 |
Migraine and cluster headache - the common link.
Topics: Calcitonin Gene-Related Peptide; Cluster Headache; Deep Brain Stimulation; Humans; Implantable Neuro | 2018 |
Experimental models for the study of cluster headache.
Topics: Animals; Cats; Cluster Headache; Disease Models, Animal; Humans; Nitroglycerin; Rats; Vasodilator Ag | 1999 |
[Clinical characteristics of cluster headache].
Topics: Chronic Disease; Cluster Headache; Humans; Nitroglycerin; Pulse; Vascular Headaches | 1989 |
3 trials available for nitroglycerin and Atypical Cluster Headache
| Article | Year |
|---|---|
Areas of cerebral blood flow changes on arterial spin labelling with the use of symmetric template during nitroglycerin triggered cluster headache attacks.
Topics: Adolescent; Adult; Brain; Brain Mapping; Cerebrovascular Circulation; Cluster Headache; Humans; Magn | 2022 |
Pain induces decrease of blood flow in the common carotid arteries in cluster headache attacks.
Topics: Adult; Aged; Blood Pressure; Carotid Artery, Common; Cerebrovascular Circulation; Cluster Headache; | 1993 |
The effect of intranasal cocaine and lidocaine on nitroglycerin-induced attacks in cluster headache.
Topics: Administration, Intranasal; Adult; Anesthetics, Local; Cluster Headache; Cocaine; Double-Blind Metho | 2000 |
24 other studies available for nitroglycerin and Atypical Cluster Headache
| Article | Year |
|---|---|
Cluster Headache.
Topics: Adult; Alcohol Drinking; Cluster Headache; Female; Humans; Male; Nitroglycerin; Oxygen; Pain; Physic | 2022 |
Comprehensive clinical phenotyping of nitroglycerin infusion induced cluster headache attacks.
Topics: Adult; Autonomic Nervous System Diseases; Cluster Headache; Cross-Over Studies; Female; Humans; Infu | 2021 |
Nitric oxide pathway and response to nitroglycerin in cluster headache patients: plasma nitrite and citrulline levels.
Topics: Adult; Analysis of Variance; Citrulline; Cluster Headache; Female; Humans; Male; Middle Aged; Nitric | 2003 |
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches.
Topics: Adult; Cluster Headache; Female; Humans; Male; Migraine Disorders; Nitroglycerin; Pedigree; Predicti | 2004 |
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches.
Topics: Adult; Cluster Headache; Female; Humans; Male; Migraine Disorders; Nitroglycerin; Pedigree; Predicti | 2004 |
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches.
Topics: Adult; Cluster Headache; Female; Humans; Male; Migraine Disorders; Nitroglycerin; Pedigree; Predicti | 2004 |
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches.
Topics: Adult; Cluster Headache; Female; Humans; Male; Migraine Disorders; Nitroglycerin; Pedigree; Predicti | 2004 |
Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action.
Topics: Adult; Chronic Disease; Cluster Headache; Deep Brain Stimulation; Drug Resistance; Female; Follow-Up | 2005 |
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches.
Topics: Adult; Cluster Headache; Humans; Migraine Disorders; Nitroglycerin; Predictive Value of Tests | 2005 |
Tomographic determination of cerebral blood flow during attacks of cluster headache.
Topics: Adult; Cerebrovascular Circulation; Cluster Headache; Ethanol; Humans; Male; Middle Aged; Nitroglyce | 1984 |
[Nosologic definition, pathogenesis and diagnosis of headache].
Topics: Adolescent; Adult; Cluster Headache; Fundus Oculi; Headache; Histamine; Humans; Nitroglycerin; Prola | 1982 |
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack.
Topics: Adult; Calcitonin Gene-Related Peptide; Cluster Headache; Humans; Male; Nitroglycerin; Remission Ind | 1995 |
Bilateral Horner's syndrome in cluster type headaches.
Topics: Cluster Headache; Dominance, Cerebral; Horner Syndrome; Humans; Iris; Male; Middle Aged; Neurologic | 1993 |
Right-lateralised central processing for pain of nitroglycerin-induced cluster headache.
Topics: Adult; Brain; Cerebrovascular Circulation; Cluster Headache; Female; Functional Laterality; Gyrus Ci | 1996 |
Chronic cluster headache: provocation with carbon dioxide breathing and nitroglycerin.
Topics: Administration, Inhalation; Adult; Aged; Carbon Dioxide; Chronic Disease; Cluster Headache; Female; | 1996 |
Responsiveness of the trigeminovascular system to nitroglycerine in cluster headache patients.
Topics: Adult; Brain; Calcitonin Gene-Related Peptide; Cluster Headache; Female; Humans; Male; Middle Aged; | 1997 |
Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks.
Topics: Adult; Animals; Baroreflex; Cluster Headache; Female; Humans; Male; Middle Aged; Muscles; Nitroglyce | 1997 |
Hypothalamic activation in cluster headache attacks.
Topics: Adult; Case-Control Studies; Cerebrovascular Circulation; Circadian Rhythm; Cluster Headache; Humans | 1998 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Brainstem activation specific to migraine headache.
Topics: Adult; Brain Stem; Cluster Headache; Humans; Male; Migraine without Aura; Nitroglycerin; Tomography, | 2001 |
Cerebrospinal fluid pressure and venous pressure in "dynamite headache" and cluster headache attacks.
Topics: Adult; Aged; Cerebral Veins; Cerebrospinal Fluid Pressure; Cluster Headache; Female; Frontal Lobe; H | 1992 |
MRI of intracranial arteries in nitroglycerin induced cluster headache attacks.
Topics: Cerebral Arteries; Cluster Headache; Humans; Magnetic Resonance Imaging; Nitroglycerin; Pain; Vasoco | 1992 |
Cluster headache and "dynamite headache": blood flow velocities in the middle cerebral artery.
Topics: Adult; Aged; Blood Flow Velocity; Cerebral Arteries; Cluster Headache; Female; Humans; Male; Middle | 1990 |
Studies on nitroglycerin and histamine provoked cluster headache attacks.
Topics: Adult; Cluster Headache; Histamine; Humans; Male; Middle Aged; Nitroglycerin; Time Factors; Vascular | 1990 |
Cluster headache: transcranial Doppler ultrasound and rCBF studies.
Topics: Adult; Blood Flow Velocity; Cerebral Arteries; Cerebrovascular Circulation; Cluster Headache; Humans | 1990 |
Association of sustained oxyhemoglobin desaturation and onset of cluster headache attacks.
Topics: Adult; Cluster Headache; Female; Humans; Hypoxia; Male; Middle Aged; Monitoring, Physiologic; Nitrog | 1990 |
Calcium entry blocker: treatment in acute pain in cluster headache patients.
Topics: Blood Pressure; Cluster Headache; Humans; Indomethacin; Lithium; Nitroglycerin; Pain Measurement; Pu | 1986 |
Extracranial vascular responses to sublingual nitroglycerin and oxygen inhalation in cluster headache patients.
Topics: Adult; Cluster Headache; Humans; Middle Aged; Nitroglycerin; Orbit; Oxygen; Pulse; Regional Blood Fl | 1985 |