Page last updated: 2024-11-01

nitroglycerin and Atherogenesis

nitroglycerin has been researched along with Atherogenesis in 35 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"We measured nitroglycerine-induced vasodilation and FMD in 436 subjects who underwent health examinations (mean age, 53 ± 19 years; age range, 19-86 years), including patients with cardiovascular diseases."3.79Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation. ( Chayama, K; Fujimura, N; Goto, C; Hidaka, T; Higashi, Y; Idei, N; Iwamoto, Y; Kajikawa, M; Kihara, Y; Maruhashi, T; Matsumoto, T; Mikami, S; Nakashima, A; Noma, K; Soga, J, 2013)
"We measured brachial IMT, FMD, and nitroglycerine-induced vasodilation by ultrasound in 388 subjects who underwent health examination (mean age, 45±22 years; age range, 19-86), including patients with cardiovascular diseases."3.78Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors. ( Chayama, K; Fujii, Y; Fujimura, N; Higashi, Y; Idei, N; Iwamoto, Y; Kajikawa, M; Kihara, Y; Maruhashi, T; Matsumoto, T; Mikami, S; Nakashima, A; Noma, K, 2012)
"The treatment of type 2 diabetes mellitus patients with sitagliptin reverses vascular endothelial dysfunction, as evidenced by increase in the FMD, and improvement of the adiponectin levels."2.77The dipeptidyl peptidase-4 inhibitor sitagliptin improves vascular endothelial function in type 2 diabetes. ( Ikeda, T; Kirinoki-Ichikawa, S; Kubota, Y; Miyamoto, M; Mizuno, K; Takagi, G; Tanaka, K, 2012)
" The failure of synthesis and/or the lost of nitric oxide bioavailability is the major feature of endothelial dysfunction and key factor initiating progression of atherosclerosis."2.44[Endothelium and nitric oxide]. ( Garaliene, V, 2008)
"Functional atherosclerosis is present in inflammatory bowel disease before early structural changes occur in vasculature."1.38Evaluation of early atherosclerosis in patients with inflammatory bowel disease. ( Akarsu, M; Akpinar, H; Cullu, N; Demir, S; Goktay, Y; Kayahan, H; Sari, I; Unsal, B; Yuksel, F, 2012)
"Fifty MCTD patients and 38 healthy age-matched and sex-matched controls were enrolled in this study."1.36Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease. ( Bereczki, D; Bodolay, E; Csipo, I; Der, H; Hajas, A; Magyar, MT; Paragh, G; Soltesz, P; Szegedi, G; Szodoray, P, 2010)
"Patients with Peyronie's disease have evidence of systemic vascular changes in the way of systemic conduit artery endothelial impairment even in the absence of RFs for atherosclerosis and endothelial dysfunction."1.35Systemic vascular endothelial dysfunction in Peyronie's disease. ( Agrawal, V; Donald, A; Ellins, E; Halcox, J; Minhas, S; Ralph, DJ, 2008)
"The atherosclerosis is associated with increased arterial stiffness, endothelial dysfunction and elevated oxidative stress and inflammation."1.35Comparison of markers of oxidative stress, inflammation and arterial stiffness between incident hemodialysis and peritoneal dialysis patients--an observational study. ( Coombes, JS; Driver, R; Fassett, RG; Geraghty, DP; Healy, H; Ranganathan, D; Ratanjee, S; Robertson, IK; Sharman, JE, 2009)
"The pathogenesis of systemic sclerosis (SSc) includes vasculopathy with endothelial dysfunction."1.34Endothelial dysfunction precedes atherosclerosis in systemic sclerosis--relevance for prevention of vascular complications. ( Dér, H; Kerekes, G; Shoenfeld, Y; Soltész, P; Szamosi, S; Szegedi, G; Szekanecz, Z; Szucs, G; Tímár, O, 2007)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.86)18.7374
1990's0 (0.00)18.2507
2000's17 (48.57)29.6817
2010's17 (48.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maruhashi, T6
Kihara, Y6
Higashi, Y6
Soga, J2
Fujimura, N3
Idei, N3
Mikami, S3
Iwamoto, Y4
Kajikawa, M4
Matsumoto, T4
Hidaka, T3
Chayama, K5
Noma, K5
Nakashima, A4
Goto, C3
Oda, N2
Iwamoto, A2
Bullock-Palmer, R1
Kontak, A1
Dickert, NW1
Shaw, LJ1
Dilsizian, V1
Holly, TA1
Shirani, J1
Dorbala, S1
Einstein, AJ1
Rusu, CC1
Ghervan, L1
Racasan, S1
Kacsa, I1
Moldovan, D1
Potra, A1
Bondor, C1
Anton, F1
Patiu, IM1
Caprioara, MG1
Hida, E1
Kishimoto, S1
Matsui, S1
Aibara, Y1
Hohl, M1
Linz, D1
Fries, P1
Müller, A1
Stroeder, J1
Urban, D1
Speer, T1
Geisel, J1
Hummel, B1
Laufs, U1
Schirmer, SH1
Böhm, M1
Mahfoud, F1
Hussein, G1
Bughdady, Y1
Kandil, ME1
Bazaraa, HM1
Taher, H1
Kovaite, M1
Petrulioniene, Z1
Ryliskyte, L1
Badariene, J1
Dzenkeviciute, V1
Cypiene, A1
Laucevicius, A1
Polena, S1
Gintautas, J1
Agrawal, V1
Ellins, E1
Donald, A1
Minhas, S1
Halcox, J1
Ralph, DJ1
Garaliene, V1
Lin, TK1
Weng, CY1
Wang, WC1
Chen, CC1
Lin, IM1
Lin, CL1
Chung, WB1
Hamburg, NM1
Holbrook, M1
Shenouda, SM1
Dohadwala, MM1
Terry, DF1
Gokce, N1
Vita, JA1
Fassett, RG1
Driver, R1
Healy, H1
Ranganathan, D1
Ratanjee, S1
Robertson, IK1
Geraghty, DP1
Sharman, JE1
Coombes, JS1
Ulusoy, RE1
Karabudak, O1
Yokusoglu, M1
Kilicaslan, F1
Kirilmaz, A1
Cebeci, BS1
Soltesz, P2
Bereczki, D1
Szodoray, P1
Magyar, MT1
Der, H2
Csipo, I1
Hajas, A1
Paragh, G1
Szegedi, G2
Bodolay, E1
Chłopicki, S1
Akamatsu, D1
Sato, A1
Goto, H1
Watanabe, T1
Hashimoto, M1
Shimizu, T1
Sugawara, H1
Sato, H1
Nakano, Y1
Miura, T1
Zukeran, T1
Serizawa, F1
Hamada, Y1
Tsuchida, K1
Tsuji, I1
Satomi, S1
Nishioka, K1
Hata, T1
Fujii, Y2
Teragawa, H1
Alibaz Oner, F1
Yurdakul, S1
Oner, E1
Kubat Uzum, A1
Erguney, M1
Mamedov, MN1
Digigova, RT1
Sharvadze, GG1
Ugurchieva, ZO1
Kovrigina, MN1
Stroeva, MV1
Jacomella, V1
Husmann, M1
Thalhammer, C1
Uike, K1
Pfammatter, T1
Amann-Vesti, B1
Kayahan, H1
Sari, I1
Cullu, N1
Yuksel, F1
Demir, S1
Akarsu, M1
Goktay, Y1
Unsal, B1
Akpinar, H1
Kubota, Y1
Miyamoto, M1
Takagi, G1
Ikeda, T1
Kirinoki-Ichikawa, S1
Tanaka, K1
Mizuno, K1
DEC, L1
Adams, MR1
Golden, DL1
Williams, JK1
Franke, AA1
Register, TC1
Kaplan, JR1
Jensen, SA1
Sørensen, JB1
Xiang, GD1
He, YS1
Zhao, LS1
Hou, J1
Yue, L1
Xiang, HJ1
Kato, T1
Inoue, T1
Morooka, T1
Yoshimoto, N1
Node, K1
Duchna, HW1
Stoohs, R1
Guilleminault, C1
Christine Anspach, M1
Schultze-Werninghaus, G1
Orth, M1
Szucs, G1
Tímár, O1
Szekanecz, Z1
Kerekes, G1
Szamosi, S1
Shoenfeld, Y1
Aggoun, Y1
Farpour-Lambert, NJ1
Marchand, LM1
Golay, E1
Maggio, AB1
Beghetti, M1
Aittokallio, J1
Polo, O1
Hiissa, J1
Virkki, A1
Toikka, J1
Raitakari, O1
Saaresranta, T1
Aittokallio, T1
Ashfaq, S1
Abramson, JL1
Jones, DP1
Rhodes, SD1
Weintraub, WS1
Hooper, WC1
Vaccarino, V1
Alexander, RW1
Harrison, DG1
Quyyumi, AA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain[NCT03026101]20 participants (Anticipated)Interventional2017-01-31Enrolling by invitation
Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hypothyroidism[NCT02090907]Phase 2/Phase 350 participants (Actual)Interventional2013-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nitroglycerin and Atherogenesis

ArticleYear
Assessment of endothelium-independent vasodilation: from methodology to clinical perspectives.
    Journal of hypertension, 2018, Volume: 36, Issue:7

    Topics: Angiography; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Coronary Vessels; Endotheliu

2018
[Endothelium and nitric oxide].
    Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Endothelium, Vascular; Homeostasis; Human

2008
[The vascular endothelium and pharmacological therapy of atherothrombosis].
    Kardiologia polska, 2003, Volume: 59 Suppl 2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis;

2003
[Detection of erectile dysfunction and peculiarities of its treatment in men with high cardiovascular risk].
    Kardiologiia, 2010, Volume: 50, Issue:11

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Cardiovascul

2010

Trials

4 trials available for nitroglycerin and Atherogenesis

ArticleYear
Doppler assessment of brachial artery flow as a measure of endothelial dysfunction in pediatric chronic renal failure.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:11

    Topics: Adolescent; Atherosclerosis; Brachial Artery; Calcium; Child; Endothelium, Vascular; Female; Humans;

2008
Evaluation of the effect of L-thyroxin therapy on endothelial functions in patients with subclinical hypothyroidism.
    Endocrine, 2011, Volume: 40, Issue:2

    Topics: Adult; Atherosclerosis; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Female; Hormone

2011
The dipeptidyl peptidase-4 inhibitor sitagliptin improves vascular endothelial function in type 2 diabetes.
    Journal of Korean medical science, 2012, Volume: 27, Issue:11

    Topics: Adiponectin; Aged; Aged, 80 and over; Atherosclerosis; Diabetes Mellitus, Type 2; Dipeptidyl-Peptida

2012
Short-term passive smoking causes endothelial dysfunction via oxidative stress in nonsmokers.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:5

    Topics: Adult; Atherosclerosis; Biomarkers; Brachial Artery; Cholesterol; Dinoprost; Endothelium, Vascular;

2006

Other Studies

27 other studies available for nitroglycerin and Atherogenesis

ArticleYear
Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Angiography; Atherosclerosis; Blo

2013
Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease.
    Atherosclerosis, 2014, Volume: 235, Issue:1

    Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Case-Control Studies; Endothelium, Vascular; Female;

2014
Responsibility for follow-up of abnormal findings in myocardial perfusion imaging: A case-based ethics discussion.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015, Volume: 22, Issue:5

    Topics: Aged, 80 and over; Angioplasty; Atherosclerosis; Blood Pressure; Cardiology; Communication; Decision

2015
Nitroglycerin mediated dilation evaluated by ultrasound is associated with sTWEAK in hemodialysis patients.
    Medical ultrasonography, 2016, Volume: 18, Issue:1

    Topics: Atherosclerosis; Biomarkers; Cytokine TWEAK; Echocardiography; Female; Humans; Male; Middle Aged; Ni

2016
Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Adult; Aged; Atherosclerosis; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Cohort

2016
Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats.
    Journal of translational medicine, 2016, 06-08, Volume: 14, Issue:1

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Carbachol; Denervat

2016
Systemic assessment of arterial wall structure and function in metabolic syndrome.
    Proceedings of the Western Pharmacology Society, 2007, Volume: 50

    Topics: Adult; Aged; Arteries; Atherosclerosis; Carotid Arteries; Dilatation; Endothelium, Vascular; Female;

2007
Systemic vascular endothelial dysfunction in Peyronie's disease.
    The journal of sexual medicine, 2008, Volume: 5, Issue:11

    Topics: Adult; Aged; Atherosclerosis; Endothelium, Vascular; Humans; Hyperemia; Male; Middle Aged; Nitroglyc

2008
Hostility trait and vascular dilatory functions in healthy Taiwanese.
    Journal of behavioral medicine, 2008, Volume: 31, Issue:6

    Topics: Aged; Atherosclerosis; Endothelial Cells; Female; Hostility; Humans; Male; Middle Aged; Nitroglyceri

2008
The brachial artery remodels to maintain local shear stress despite the presence of cardiovascular risk factors.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:4

    Topics: Adaptation, Physiological; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Atherosclerosis;

2009
Comparison of markers of oxidative stress, inflammation and arterial stiffness between incident hemodialysis and peritoneal dialysis patients--an observational study.
    BMC nephrology, 2009, Mar-12, Volume: 10

    Topics: Atherosclerosis; Brachial Artery; C-Reactive Protein; Carotid Arteries; Clinical Trials as Topic; Ec

2009
Noninvasive assessment of impaired endothelial function in psoriasis.
    Rheumatology international, 2010, Volume: 30, Issue:4

    Topics: Atherosclerosis; Brachial Artery; Echocardiography, Doppler; Endothelium, Vascular; Humans; Male; Ni

2010
Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease.
    Arthritis research & therapy, 2010, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Antibodies; Atherosclerosis; Autoantibodies; Biomarkers; Brachial Artery; C

2010
Nitroglycerin-mediated vasodilatation of the brachial artery may predict long-term cardiovascular events irrespective of the presence of atherosclerotic disease.
    Journal of atherosclerosis and thrombosis, 2010, Dec-26, Volume: 17, Issue:12

    Topics: Aged; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Humans; Kinetics; Middle Aged; Nitr

2010
Vascular function and circulating progenitor cells in thromboangitis obliterans (Buerger's disease) and atherosclerosis obliterans.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Arteriosclerosis Obliterans; Atherosclerosis; C-Reactive Protein

2011
Impact of endovascular treatment of atherosclerotic renal artery stenosis on endothelial function and arterial blood pressure.
    International angiology : a journal of the International Union of Angiology, 2012, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Atherosclerosis; Blood Flow Velocity; Blood Pressure;

2012
Evaluation of early atherosclerosis in patients with inflammatory bowel disease.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:8

    Topics: Adult; Atherosclerosis; Brachial Artery; Carotid Intima-Media Thickness; Case-Control Studies; Colit

2012
Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Carotid A

2012
[Ballistocardiogram after smoking and nitroglycerin as a diagnostic test in atherosclerosis of the coronary vessels].
    Polskie Archiwum Medycyny Wewnetrznej, 1960, Volume: 30

    Topics: Atherosclerosis; Ballistocardiography; Coronary Disease; Coronary Vessels; Diagnostic Tests, Routine

1960
Soy protein containing isoflavones reduces the size of atherosclerotic plaques without affecting coronary artery reactivity in adult male monkeys.
    The Journal of nutrition, 2005, Volume: 135, Issue:12

    Topics: Animal Feed; Animals; Atherosclerosis; Coronary Circulation; Coronary Vessels; Diet, Atherogenic; Di

2005
Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Atherosclerosis; Capecitabine;

2006
Impairment of endothelium-dependent arterial dilation in Hashimoto's thyroiditis patients with euthyroidism.
    Clinical endocrinology, 2006, Volume: 64, Issue:6

    Topics: Atherosclerosis; Autoantibodies; Brachial Artery; Case-Control Studies; Cholesterol, LDL; Endotheliu

2006
Vascular endothelial dysfunction in patients with mild obstructive sleep apnea syndrome.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:21-22

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Body Mass Index; Bradykinin; Continuous Positive Airway Pr

2006
Endothelial dysfunction precedes atherosclerosis in systemic sclerosis--relevance for prevention of vascular complications.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:5

    Topics: Adult; Age Factors; Aged; Atherosclerosis; Brachial Artery; Carotid Artery, Common; Endothelium, Vas

2007
Impaired endothelial and smooth muscle functions and arterial stiffness appear before puberty in obese children and are associated with elevated ambulatory blood pressure.
    European heart journal, 2008, Volume: 29, Issue:6

    Topics: Atherosclerosis; Blood Pressure; Brachial Artery; Carotid Artery Diseases; Carotid Artery, Common; C

2008
Overnight variability in transcutaneous carbon dioxide predicts vascular impairment in women.
    Experimental physiology, 2008, Volume: 93, Issue:7

    Topics: Adult; Atherosclerosis; Biomarkers; Blood Gas Monitoring, Transcutaneous; Carbon Dioxide; Carotid Ar

2008
Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:1

    Topics: Adult; Aged; Atherosclerosis; Biomarkers; Brachial Artery; Cysteine; Endothelium, Vascular; Female;

2008