nitroglycerin has been researched along with Arteriosclerosis, Coronary in 181 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we investigated the effects of both 25 and 50 mg daily doses of rofecoxib on the endothelial functions of patients with coronary artery disease (CAD)." | 9.11 | Selective COX-2 inhibition with different doses of rofecoxib does not impair endothelial function in patients with coronary artery disease. ( Bayindir, P; Bayturan, O; Ekmekçi, C; Tikiz, C; Tikiz, H; Utük, O, 2005) |
| "To investigate the effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease (CAD)." | 9.11 | The effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease. ( Bedding, A; Braat, S; Effron, M; Emmick, J; Kloner, R; MacDonald, T; Mitchell, M; Patterson, D; Warner, M, 2005) |
| " The aim of the present study was to compare the efficacy of nitroglycerin transdermal patches intermittently or continuously administered to patients with myocardial ischemia evaluated by the echocardiography dipyridamole stress test." | 9.10 | Efficacy of transdermal nitroglycerin patches evaluated by dipyridamole-induced myocardial ischemia in patients with coronary artery disease. Comparison between continuous and intermittent schedule. ( Abete, P; Ferrara, N; Furgi, G; Leosco, D; Longobardi, G; Nicolino, A; Rengo, F; Vitale, DF, 2002) |
| "Nitroglycerin (Ntg) is known to increase blood flow to the hypoperfused myocardial area and thus to reduce regional ischaemia of the heart muscle in coronary artery disease (CAD)." | 9.10 | The influence of nitroglycerin on myocardial 99mTc-Tetrofosmin uptake defects in coronary artery disease. ( Cholewiński, W; Chrapko, B; Poniatowicz-Frasunek, E; Stefaniak, B; Tarkowska, A; Widomska-Czekajska, T; Wypych, M, 2002) |
| "To determine the accuracy of using nitroglycerine as a 'test of treatment' in the diagnosis of cardiac chest pain we undertook a systematic review of studies of diagnostic accuracy." | 8.88 | Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic review. ( Glasziou, PP; Grailey, K, 2012) |
| "We measured nitroglycerine-induced vasodilation in coronary and brachial arteries in 30 subjects with suspected coronary artery disease who underwent coronary angiography (19 men and 11 women; mean age, 69." | 7.83 | Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease. ( Aibara, Y; Chayama, K; Goto, C; Hidaka, T; Higaki, T; Higashi, Y; Ikenaga, H; Iwamoto, A; Iwamoto, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oda, N; Shimonaga, T; Watanabe, N, 2016) |
| "ACC/AHA/ESC guidelines recommend sublingual nitroglycerin (SNG) in patients with stable angina pectoris and coronary artery disease (CAD)." | 7.77 | [Frequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drug]. ( Cuğlan, B; Eryonucu, B; Keskin, G; Selçoki, Y; Soran, O; Temizkan, A; Yılmaz, OC, 2011) |
| "It is controversial as to whether or not nitroglycerin (NTG) increases subendocardial myocardial blood flow (SMBF), and if it does, whether arterial or venous blood flow is increased in patients with coronary artery disease." | 7.77 | Nitroglycerin-induced heterogeneous subendocardial myocardial blood flow observed by cardioscopy in patients with coronary artery disease. ( Kanai, M; Maezawa, Y; Sakurai, T; Shirai, S; Tabata, T; Uchida, Y, 2011) |
| "In women with suspected myocardial ischemia, higher genistein blood levels are associated with impaired nonendothelial-dependent and endothelial-dependent coronary microvascular function." | 7.74 | Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study. ( Bairey Merz, CN; Johnson, BD; Kelsey, SF; Kerensky, RA; McGorray, SP; Pepine, CJ; Pohost, G; Reis, SE; Rogers, WJ; Sopko, G; von Mering, GO, 2007) |
| "In 289 patients with coronary artery disease we assessed coronary endothelium-dependent and -independent vascular responses to intracoronary infusion of acetylcholine, adenosine, and nitroglycerin, respectively, and determined plasma ADMA and l-arginine concentrations by HPLC." | 7.74 | Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia. ( Böger, RH; Lüscher, TF; Maas, R; Quitzau, K; Rafflenbeul, W; Schwedhelm, E; Spieker, L; Steenpass, A, 2007) |
| "Twenty-two patients (17 men; mean age 58+/-12 years) with a first acute myocardial infarction (5 anterior (23%) and 17 (77%) inferior) who showed ST-segment elevation during a dobutamine echo stress test performed early (7+/-5 days) after the acute event where included in the analysis." | 7.72 | Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery. ( Canosi, U; Klersy, C; Lanzarini, L; Previtali, M; Scelsi, L; Sebastiani, R, 2003) |
| "Rotational atherectomy (RA) may cause bradyarrhythmias and transitory atrioventricular block when performed in the right coronary artery (RCA) or a dominant circumflex (CX) coronary artery." | 7.30 | A mix of aminophylline and heparin plus nitroglycerin can reduce bradycardia during rotational atherectomy on the right coronary artery and dominant circumflex artery. ( Acar, E; Donmez, I; Güneş, Y; Izci, S; Izgi, IA; Kayabası, O; Kaygusuz, T; Kirma, C; Ozcan, E; Ozgul, N, 2023) |
| "Niacin treatment was without effect on FMD or NMD, respectively, compared to placebo." | 6.74 | Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study. ( Blankenberg, S; Elsner, V; Lackner, K; Munzel, T; Ostad, MA; Peetz, D; Schinzel, R; Stieber, F; Walter, U; Warnholtz, A; Wild, P, 2009) |
| "In this cross-over clinical trial, thirty patients, diagnosed with coronary artery disease (CAD) and flow mediated dilation to nitroglycerin dependent vasodilation (FMD/NMD) ratio less than 1, were included." | 5.24 | The Assessment of short-term effect of L-Citrulline on endothelial function via FMD to NMD ratio in known CAD patients: A randomized, cross-over clinical trial (Clinical trial number: NCT02638727). ( Akbarzadeh, MA; Khaheshi, I; Mahjoob, MP; Naderian, M; Nateghi, S; Safi, M, 2017) |
| "This study sought to examine the efficacy of ranolazine versus placebo on weekly angina frequency and sublingual nitroglycerin use in subjects with type 2 diabetes mellitus, coronary artery disease (CAD), and chronic stable angina who remain symptomatic despite treatment with up to 2 antianginal agents." | 5.17 | Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). ( Arnold, SV; Belardinelli, L; Ben-Yehuda, O; Chaitman, BR; Jones, PG; Katz, A; Kosiborod, M; Li, Y; McGuire, DK; Olmsted, A; Spertus, JA; Yue, P, 2013) |
| "Preoperative atorvastatin treatment in patients with coronary artery disease increases plasma NO levels before and after reactive hyperemia prior to surgery." | 5.14 | The effect of statin therapy on stimulation of endothelium-derived nitric oxide before and after coronary artery bypass surgery. ( Aydin, C; Baysal, A; Bugra, O; Buyukbayrak, F; Caliskan, A; Erdem, H; Fedekar, A; Sasmazel, A; Sunar, H, 2010) |
| "In this study, we investigated the effects of both 25 and 50 mg daily doses of rofecoxib on the endothelial functions of patients with coronary artery disease (CAD)." | 5.11 | Selective COX-2 inhibition with different doses of rofecoxib does not impair endothelial function in patients with coronary artery disease. ( Bayindir, P; Bayturan, O; Ekmekçi, C; Tikiz, C; Tikiz, H; Utük, O, 2005) |
| "To investigate the effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease (CAD)." | 5.11 | The effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease. ( Bedding, A; Braat, S; Effron, M; Emmick, J; Kloner, R; MacDonald, T; Mitchell, M; Patterson, D; Warner, M, 2005) |
| "To investigate the effects of non-ECG-triggered imaging during ultrasound studies of endothelial function, brachial artery diameters were measured throughout the cardiac cycle at rest, during reactive hyperemia, and after administration of nitroglycerin." | 5.10 | Effect of cardiac cycle on ultrasound assessment of endothelial function. ( Bisinov, EA; Chuang, ML; Douglas, PS; Stein, JH, 2002) |
| " The aim of the present study was to compare the efficacy of nitroglycerin transdermal patches intermittently or continuously administered to patients with myocardial ischemia evaluated by the echocardiography dipyridamole stress test." | 5.10 | Efficacy of transdermal nitroglycerin patches evaluated by dipyridamole-induced myocardial ischemia in patients with coronary artery disease. Comparison between continuous and intermittent schedule. ( Abete, P; Ferrara, N; Furgi, G; Leosco, D; Longobardi, G; Nicolino, A; Rengo, F; Vitale, DF, 2002) |
| "Nitroglycerin (Ntg) is known to increase blood flow to the hypoperfused myocardial area and thus to reduce regional ischaemia of the heart muscle in coronary artery disease (CAD)." | 5.10 | The influence of nitroglycerin on myocardial 99mTc-Tetrofosmin uptake defects in coronary artery disease. ( Cholewiński, W; Chrapko, B; Poniatowicz-Frasunek, E; Stefaniak, B; Tarkowska, A; Widomska-Czekajska, T; Wypych, M, 2002) |
| "The aim of this study was to assess the influence of incremental nitroglycerin infusion (NTG+Inf) on the myocardial uptake of 99mTc-tetrofosmin (TF) in order to determine whether nitrates enhance the detection of viable myocardium with TF in patients with coronary artery disease (CAD) and left ventricular dysfunction." | 5.10 | Technetium-99m-tetrofosmin imaging with incremental nitroglycerin infusion to detect severely ischaemic but viable myocardium: a comparative study with thallium-201. ( Ergin, A; Kula, M; Topsakal, R; Tutuş, A; Unal, S, 2003) |
| "Cocaine induces vasoconstriction of epicardial coronary arteries in patients with and without coronary artery disease, and this vasoconstriction is particularly marked in segments narrowed by atherosclerosis." | 5.07 | Alleviation of cocaine-induced coronary vasoconstriction by nitroglycerin. ( Brogan, WC; Hillis, LD; Kim, AS; Lange, RA; Moliterno, DJ, 1991) |
| "Short-acting nitrates are beneficial in acute myocardial ischemia." | 4.91 | Use of nitrates in ischemic heart disease. ( Giuseppe, C; Hans-Ulrich, I; Paul, J, 2015) |
| "To determine the accuracy of using nitroglycerine as a 'test of treatment' in the diagnosis of cardiac chest pain we undertook a systematic review of studies of diagnostic accuracy." | 4.88 | Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic review. ( Glasziou, PP; Grailey, K, 2012) |
| "The purpose of this study was to clarify the difference between effects of nitroglycerin (NTG) on the functional stiffness in patients with and without coronary artery disease (CAD) using a newly developed stiffness index, cardio-ankle vascular index (CAVI)." | 3.83 | Effect of nitroglycerin administration on cardio-ankle vascular index. ( Noike, H; Sato, S; Shimizu, K; Shirai, K; Takahashi, M; Yamamoto, T, 2016) |
| "We measured nitroglycerine-induced vasodilation in coronary and brachial arteries in 30 subjects with suspected coronary artery disease who underwent coronary angiography (19 men and 11 women; mean age, 69." | 3.83 | Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease. ( Aibara, Y; Chayama, K; Goto, C; Hidaka, T; Higaki, T; Higashi, Y; Ikenaga, H; Iwamoto, A; Iwamoto, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oda, N; Shimonaga, T; Watanabe, N, 2016) |
| "ACC/AHA/ESC guidelines recommend sublingual nitroglycerin (SNG) in patients with stable angina pectoris and coronary artery disease (CAD)." | 3.77 | [Frequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drug]. ( Cuğlan, B; Eryonucu, B; Keskin, G; Selçoki, Y; Soran, O; Temizkan, A; Yılmaz, OC, 2011) |
| "It is controversial as to whether or not nitroglycerin (NTG) increases subendocardial myocardial blood flow (SMBF), and if it does, whether arterial or venous blood flow is increased in patients with coronary artery disease." | 3.77 | Nitroglycerin-induced heterogeneous subendocardial myocardial blood flow observed by cardioscopy in patients with coronary artery disease. ( Kanai, M; Maezawa, Y; Sakurai, T; Shirai, S; Tabata, T; Uchida, Y, 2011) |
| " Using a high-resolution ultrasound, the diameter of the brachial artery at rest and during reactive hyperemia (flow-mediated dilatation, FMD%: endothelial-dependent stimulus to vasodilatation), as well as after sublingual administration of nitroglycerin (NTG%: endothelium-independent vasodilatation), was measured." | 3.74 | Relationship between endothelial function and coronary risk factors in patients with stable coronary artery disease. ( Akcakoyun, M; Barutcu, I; Boztosun, B; Esen, AM; Izgi, A; Karakaya, O; Kargin, R; Kirma, C; Saglam, M; Sonmez, K; Turkmen, M, 2007) |
| "In women with suspected myocardial ischemia, higher genistein blood levels are associated with impaired nonendothelial-dependent and endothelial-dependent coronary microvascular function." | 3.74 | Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study. ( Bairey Merz, CN; Johnson, BD; Kelsey, SF; Kerensky, RA; McGorray, SP; Pepine, CJ; Pohost, G; Reis, SE; Rogers, WJ; Sopko, G; von Mering, GO, 2007) |
| "In 289 patients with coronary artery disease we assessed coronary endothelium-dependent and -independent vascular responses to intracoronary infusion of acetylcholine, adenosine, and nitroglycerin, respectively, and determined plasma ADMA and l-arginine concentrations by HPLC." | 3.74 | Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia. ( Böger, RH; Lüscher, TF; Maas, R; Quitzau, K; Rafflenbeul, W; Schwedhelm, E; Spieker, L; Steenpass, A, 2007) |
| "Twenty-two patients (17 men; mean age 58+/-12 years) with a first acute myocardial infarction (5 anterior (23%) and 17 (77%) inferior) who showed ST-segment elevation during a dobutamine echo stress test performed early (7+/-5 days) after the acute event where included in the analysis." | 3.72 | Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery. ( Canosi, U; Klersy, C; Lanzarini, L; Previtali, M; Scelsi, L; Sebastiani, R, 2003) |
| "As part of the Women's Ischemia Syndrome Evaluation (WISE) sponsored by the National Heart, Lung, and Blood Institute, 163 women referred for clinically indicated coronary angiography underwent coronary reactivity assessment with quantitative coronary angiography and intracoronary Doppler flow before and after intracoronary administration of acetylcholine, adenosine, and nitroglycerin and were then followed up for clinical outcomes." | 3.72 | Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). ( Arant, CB; Bairey Merz, CN; Handberg, E; Johnson, BD; Kerensky, RA; McGorray, SP; Olson, MB; Pepine, CJ; Sharaf, BL; Smith, KM; Sopko, G; von Mering, GO; Wessel, TR, 2004) |
| " Sixty-six patients with suspected coronary artery disease were enrolled, and a noninvasive method of brachial ultrasound was used to measure endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerin-mediated vasodilation." | 3.72 | Usefulness of attenuated heart rate recovery immediately after exercise to predict endothelial dysfunction in patients with suspected coronary artery disease. ( Chen, JW; Cheng, CM; Ding, PY; Huang, CY; Huang, PH; Leu, HB; Lin, SJ; Tuan, TC, 2004) |
| "To study smooth muscle function in atherosclerosis, we calculated dose-response curves in patients with coronary artery disease and in controls by measuring changes in brachial artery diameter after incremental sublingual doses of nitroglycerin." | 3.71 | Impaired vascular responses to nitroglycerin in subjects with coronary atherosclerosis. ( Celermajer, DS; Raitakari, OT; Seale, JP, 2001) |
| "In patients with coronary artery disease, coronary stenoses-particularly those of complex morphology-dilate in response to the administration of L-arginine but not D-arginine." | 3.71 | Vasomotor effects of L- and D-arginine in stenotic atheromatous coronary plaque. ( Davies, GJ; Goumas, G; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouzas, P, 2001) |
| "We assessed the effects of intracoronary administration of substance P, LNMMA, L-arginine, and nitroglycerin in patients with normal coronary angiograms and in patients with coronary artery disease." | 3.70 | Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine administration on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with normal coronary arteries. ( Crake, T; Davies, GJ; Katsimaglis, G; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouzas, P, 1998) |
| " Endothelium-dependent and independent stimulation of each segment from 10 patients with known significant coronary artery disease was examined with intracoronary administrations of normal saline, acetylcholine 10(-6) M and 10(-5) M, and nitroglycerin, respectively, using quantitative coronary angiography." | 3.70 | Effect of plaque burden on coronary vasoreactivity in early atherosclerosis. ( Athanassopoulos, G; Cokkinos, DV; Karatasakis, G; Manginas, A; Pavlides, G; Voudris, V, 1998) |
| "We examined the impact of serum cholesterol and cigarette smoking on the coronary vasomotor effects of L-arginine in patients with atherosclerotic coronary artery disease." | 3.70 | Serum cholesterol level, cigarette smoking, and vasomotor responses to L-arginine in narrowed epicardial coronary arteries. ( Davies, GJ; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouzas, P, 2000) |
| " In 74 coronary segments from eight patients with coronary artery disease, coronary artery diameters were measured before (C1) and 90 s after intracoronary infusion of the endothelium-dependent vasodilator bradykinin (0." | 3.67 | Konkurrenz zwischen endothelabhängiger und Nitroglygerin-induzierter koronarer Vasodilatation [Competition between endothelium-dependent and nitroglycerin-induced coronary vasodilation]. ( Bassenge, E; Lichtlen, P; Rafflenbeul, W, 1989) |
| "Rotational atherectomy (RA) may cause bradyarrhythmias and transitory atrioventricular block when performed in the right coronary artery (RCA) or a dominant circumflex (CX) coronary artery." | 3.30 | A mix of aminophylline and heparin plus nitroglycerin can reduce bradycardia during rotational atherectomy on the right coronary artery and dominant circumflex artery. ( Acar, E; Donmez, I; Güneş, Y; Izci, S; Izgi, IA; Kayabası, O; Kaygusuz, T; Kirma, C; Ozcan, E; Ozgul, N, 2023) |
| "Coronary vasodilator function and atherosclerotic plaque progression have both been shown to be associated with adverse cardiovascular events." | 2.87 | Evaluation of human coronary vasodilator function predicts future coronary atheroma progression. ( Baillie, TJ; Beltrame, JF; Delacroix, S; Honda, S; Howell, S; Kim, S; Montarello, N; Nicholls, SJ; Psaltis, PJ; Shishikura, D; Sidharta, SL; Worthley, MI; Worthley, SG, 2018) |
| "Nitroglycerin was administered prior to CT, QCA and FFR acquisition." | 2.84 | Effect of the ratio of coronary arterial lumen volume to left ventricle myocardial mass derived from coronary CT angiography on fractional flow reserve. ( Achenbach, S; Ahmadi, A; Berman, DS; Bezerra, H; Bøtker, HE; De Bruyne, B; Dey, D; Gaur, S; Jensen, JM; Khem, S; Kim, HJ; Ko, B; Leipsic, J; Lesser, J; Narula, J; Nørgaard, BL; St Goar, F; Taylor, CA; Wilk, A; Zarins, CK; Øvrehus, KA, 2017) |
| "Niacin treatment was without effect on FMD or NMD, respectively, compared to placebo." | 2.74 | Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study. ( Blankenberg, S; Elsner, V; Lackner, K; Munzel, T; Ostad, MA; Peetz, D; Schinzel, R; Stieber, F; Walter, U; Warnholtz, A; Wild, P, 2009) |
| "Investigations from basic biology suggest that activation of the Rho/Rho kinase pathway reduces the bioavailability of nitric oxide (NO) and thereby promotes atherosclerosis and its clinical complications." | 2.72 | Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease. ( Creager, MA; Ganz, P; Grunert, ME; Liao, JK; Nohria, A; Noma, K; Prsic, A; Rikitake, Y, 2006) |
| "Diltiazem was administered as an intravenous bolus of 0." | 2.71 | Comparison of antihypertensives after coronary artery surgery. ( Alhan, C; Evrenkaya, S; Goksel, O; Karabulut, H; Tarcan, S; Toraman, F, 2005) |
| "The hemodynamic and antiischemic effects of nitroglycerin (GTN) are lost upon chronic administration due to the rapid development of nitrate tolerance." | 2.46 | Organic nitrates and nitrate tolerance--state of the art and future developments. ( Daiber, A; Gori, T; Münzel, T, 2010) |
| " Furthermore, we determined whether a reduced dosage of estrogen may maintain its beneficial effects." | 2.42 | New methods to evaluate endothelial function: Non-invasive method of evaluating endothelial function in humans. ( Akita, H; Hashimoto, M; Matsuda, Y; Miyamoto, Y, 2003) |
| " A daily dosage of 75 to 150 mg is sufficient to reduce the rate of future cardiac events." | 2.42 | [Risk management of coronary artery disease--pharmacological therapy]. ( Hofmann, T, 2004) |
| "05), nitroglycerin dosage (P < 0." | 1.91 | Clinical Outcomes of Cardiac Shockwave Therapy in Severe Coronary Artery Disease Patients after Coronary Artery Bypass Grafting. ( He, Q; Jia, N; Lan, M; Liu, B; Liu, J; Wang, J; Yao, Z; Zhang, R, 2023) |
| "0) years), adverse events occurred in 68 patients (1." | 1.72 | Factors influencing the safety of outpatient coronary CT angiography: a clinical registry study. ( Andre, F; Brado, M; Buss, SJ; Emami, M; Fortner, P; Frey, N; Görich, J; Gückel, F; Seitz, S; Sokiranski, R; Sommer, A, 2022) |
| "Recurrent CP and long-term outcomes are independent of vasomotion subtypes, but long-term use of CCBs, nitrates, and statins is a significant predictor for recurrent CP." | 1.46 | Impact of vasomotion type on prognosis of coronary artery spasm induced by acetylcholine provocation test of left coronary artery. ( Choi, CU; Choi, MH; Kim, EJ; Kim, HK; Kim, JW; Kim, NH; Lee, EM; Lim, HE; Oh, DJ; Park, CG; Rha, SW; Seo, HS, 2017) |
| "Pretreatment with nitroglycerine dilates coronary arteries and increases coronary flow velocity reserve indicating that adenosine alone causes a submaximal hyperemia." | 1.43 | Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation. ( Gan, LM; Jeppsson, A; Wittfeldt, A, 2016) |
| "High adenosine dose was adequately tolerated by all patients, without requiring infusion discontinuation in any case." | 1.43 | Effect of High (200 μg/kg per Minute) Adenosine Dose Infusion on Fractional Flow Reserve Variability. ( Alexopoulos, D; Armylagos, S; Davlouros, P; Koutsogiannis, N; Moulias, A; Salata, P; Tsigkas, G; Xanthopoulou, I, 2016) |
| "The spasm was diagnosed by coronary angiography and resolved by intracoronary injection of trinitrine." | 1.39 | Early diffuse coronary artery spasm after heart valve surgery in the carcinoid syndrome. ( Anselmi, A; Boulmier, D; Corbineau, H; Ruggieri, VG, 2013) |
| "Furthermore, early coronary atherosclerosis characterised by endothelial dysfunction is associated with a decrease in coronary artery compliance and an increase in wall shear stress." | 1.36 | Coronary endothelial dysfunction is associated with a reduction in coronary artery compliance and an increase in wall shear stress. ( Gulati, R; Lerman, A; Lerman, LO; Mathew, V; Rihal, CS; Takumi, T; Yang, EH, 2010) |
| "Patients with DM and ESRD had impaired coronary vasodilation to NTG compared to age-matched controls (17." | 1.35 | Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease. ( Engvall, J; McConnell, MV; Meyer, C; Nguyen, PK; Yang, P, 2008) |
| "SCF was observed only in patients treated for acute myocardial infarction (AMI; 11." | 1.34 | Frequency of slow coronary flow following successful stent implantation and effect of Nitroprusside. ( Airoldi, F; Briguori, C; Carlino, M; Chieffo, A; Cianflone, D; Colombo, A; Cosgrave, J; Godino, C; Maseri, A; Michev, I; Montorfano, M; Mussardo, M; Stankovic, G, 2007) |
| "All eight patients had Graves' disease." | 1.33 | Severe coronary artery spasm can be associated with hyperthyroidism. ( Bae, SW; Choi, YH; Chung, JH; Jeong, EM; Kang, MG; Kim, BJ; Kim, KW; Lee, WH; Park, JE, 2005) |
| "Coronary artery ectasia has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries with a luminal dilation exceeding the 1." | 1.33 | Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery. ( Acikgoz, N; Aksoy, Y; Akturk, E; Bariskaner, E; Sivri, N; Turhan, H; Yetkin, E, 2006) |
| "Coronary artery disease is associated with impaired endothelium-dependent dilatation and impaired stimulation of t-PA release in the systemic circulation." | 1.33 | Endothelial dysfunction occurs in peripheral circulation patients with acute and stable coronary artery disease. ( Adams, MR; Celermajer, DS; Thanyasiri, P, 2005) |
| "Myocardial ischemia is associated with impaired endothelium-independent vasodilation of resistance coronary arteries and increased minimal coronary resistance." | 1.32 | Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy. ( Fukudome, T; Hamasaki, S; Ishida, S; Kataoka, T; Minagoe, S; Mizoguchi, E; Ninomiya, Y; Okui, H; Otsuji, Y; Saihara, K; Shinsato, T; Tei, C, 2004) |
| "Coronary atherosclerosis is associated with endothelial dysfunction and reduced NO activity." | 1.31 | N-acetylcysteine improves coronary and peripheral vascular function. ( Andrews, NP; Prasad, A; Quyyumi, AA, 2001) |
| "Based on our results, as coronary atherosclerosis becomes more severe, the adjusted brachial artery FMD becomes more severely impaired." | 1.30 | The correlation between coronary stenosis index and flow-mediated dilation of the brachial artery. ( Arai, Y; Hirase, H; Kaku, B; Mizuno, S; Moriuchi, I; Murakami, T; Nagata, M; Nio, Y; Ohnaka, M; Ohsato, K; Takahashi, Y, 1998) |
| " Information was obtained about the number of examinations performed, complications related to ICUS imaging, and any adverse clinical consequences related to ICUS imaging." | 1.29 | Safety of intracoronary ultrasound: data from a Multicenter European Registry. ( Batkoff, BW; Linker, DT, 1996) |
| "Stenocardia was characterized by development of attacks during rest while average loads were well tolerated by the patients." | 1.28 | [Clinical and diagnostic features of the initial forms of coronary atherosclerosis]. ( Lizogub, VG, 1989) |
| " However, in class III, there was a significant shift to the right of the dose-response curves to nitroglycerin and SIN1 (but not to forskolin)." | 1.28 | Alterations of beta-adrenoceptor mediated relaxations of atherosclerotic human coronary arteries. ( Berkenboom, G; Degre, S; Fontaine, J, 1989) |
| "Indomethacin (10(-5) M) was present to prevent possible interference from endogenously formed prostaglandins." | 1.27 | Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. ( Alheid, U; Förstermann, U; Frölich, JC; Haverich, A; Mügge, A, 1988) |
| "Accelerated coronary atherosclerosis is a major cause of graft failure after heart transplantation." | 1.27 | Responses of coronary arteries of cardiac transplant patients to acetylcholine. ( Alexander, RW; Fish, RD; Ganz, P; Kirshenbaum, JM; Ludmer, PL; Mudge, GH; Nabel, EG; Schoen, FJ; Selwyn, AP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (11.60) | 18.7374 |
| 1990's | 31 (17.13) | 18.2507 |
| 2000's | 76 (41.99) | 29.6817 |
| 2010's | 47 (25.97) | 24.3611 |
| 2020's | 6 (3.31) | 2.80 |
| Authors | Studies |
|---|---|
| Manresa-Rocamora, A | 1 |
| Ribeiro, F | 1 |
| Casanova-Lizón, A | 1 |
| Flatt, AA | 1 |
| Sarabia, JM | 1 |
| Moya-Ramón, M | 1 |
| Andre, F | 1 |
| Fortner, P | 1 |
| Emami, M | 1 |
| Seitz, S | 1 |
| Brado, M | 1 |
| Gückel, F | 1 |
| Sokiranski, R | 1 |
| Sommer, A | 1 |
| Frey, N | 1 |
| Görich, J | 1 |
| Buss, SJ | 1 |
| Wang, J | 1 |
| Jia, N | 1 |
| Liu, B | 2 |
| Zhang, R | 1 |
| Lan, M | 1 |
| Liu, J | 1 |
| Yao, Z | 1 |
| He, Q | 1 |
| Angelini, P | 1 |
| Uribe, C | 1 |
| Salem, PA | 1 |
| Acar, E | 1 |
| Izci, S | 1 |
| Donmez, I | 1 |
| Ozgul, N | 1 |
| Ozcan, E | 1 |
| Kaygusuz, T | 1 |
| Kayabası, O | 1 |
| Güneş, Y | 1 |
| Izgi, IA | 1 |
| Kirma, C | 2 |
| Lu, NH | 1 |
| Liu, YS | 1 |
| Liu, KI | 1 |
| Hsu, SY | 1 |
| Huang, YH | 1 |
| Sun, CK | 1 |
| Chen, TB | 1 |
| Vishnevsky, A | 1 |
| Julien, HM | 1 |
| Fischman, DL | 1 |
| Walinsky, P | 1 |
| David Ogilby, J | 1 |
| Ruggiero, NJ | 1 |
| Jasti, B | 1 |
| Savage, MP | 1 |
| Dudek, D | 1 |
| Rzeszutko, Ł | 1 |
| Onuma, Y | 1 |
| Sotomi, Y | 1 |
| Depukat, R | 1 |
| Veldhof, S | 1 |
| Ediebah, D | 1 |
| Staehr, P | 1 |
| Zasada, W | 1 |
| Malinowski, KP | 1 |
| Kaluza, GL | 1 |
| Serruys, PW | 1 |
| Taylor, CA | 1 |
| Gaur, S | 1 |
| Leipsic, J | 1 |
| Achenbach, S | 1 |
| Berman, DS | 1 |
| Jensen, JM | 1 |
| Dey, D | 1 |
| Bøtker, HE | 1 |
| Kim, HJ | 1 |
| Khem, S | 1 |
| Wilk, A | 1 |
| Zarins, CK | 1 |
| Bezerra, H | 1 |
| Lesser, J | 1 |
| Ko, B | 1 |
| Narula, J | 1 |
| Ahmadi, A | 1 |
| Øvrehus, KA | 1 |
| St Goar, F | 1 |
| De Bruyne, B | 1 |
| Nørgaard, BL | 1 |
| Israeli, Z | 1 |
| Bagur, R | 1 |
| Murariu, D | 1 |
| Wall, S | 1 |
| Alemayehu, M | 1 |
| Parviz, Y | 1 |
| Diamantouros, P | 1 |
| Lavi, S | 2 |
| Tawa, M | 1 |
| Kinoshita, T | 1 |
| Asai, T | 1 |
| Suzuki, T | 1 |
| Ishibashi, T | 1 |
| Okamura, T | 1 |
| Sidharta, SL | 1 |
| Baillie, TJ | 1 |
| Howell, S | 1 |
| Nicholls, SJ | 1 |
| Montarello, N | 1 |
| Honda, S | 1 |
| Shishikura, D | 1 |
| Delacroix, S | 1 |
| Kim, S | 1 |
| Beltrame, JF | 1 |
| Psaltis, PJ | 1 |
| Worthley, SG | 1 |
| Worthley, MI | 2 |
| Sepehri, ZS | 1 |
| Masoomi, M | 1 |
| Ruzbehi, F | 1 |
| Kiani, Z | 1 |
| Nasiri, AA | 1 |
| Kohan, F | 1 |
| Sheikh Fathollahi, M | 1 |
| Kazemi Arababadi, M | 1 |
| Kennedy, D | 1 |
| Asadikaram, GA | 1 |
| Horsman, C | 1 |
| Frederick, T | 1 |
| Holmes, KR | 1 |
| Fonte, TA | 1 |
| Weir-McCall, J | 1 |
| Anastasius, M | 1 |
| Blanke, P | 1 |
| Payne, GW | 1 |
| Ellis, J | 1 |
| Murphy, DT | 1 |
| Taylor, C | 1 |
| Leipsic, JA | 1 |
| Sellers, SL | 1 |
| Kosiborod, M | 1 |
| Arnold, SV | 1 |
| Spertus, JA | 1 |
| McGuire, DK | 1 |
| Li, Y | 1 |
| Yue, P | 1 |
| Ben-Yehuda, O | 1 |
| Katz, A | 1 |
| Jones, PG | 1 |
| Olmsted, A | 1 |
| Belardinelli, L | 1 |
| Chaitman, BR | 1 |
| Kiani, S | 1 |
| Aasen, JG | 1 |
| Holbrook, M | 4 |
| Khemka, A | 1 |
| Sharmeen, F | 1 |
| LeLeiko, RM | 1 |
| Tabit, CE | 1 |
| Farber, A | 1 |
| Eberhardt, RT | 1 |
| Gokce, N | 4 |
| Vita, JA | 5 |
| Hamburg, NM | 2 |
| Davlouros, P | 2 |
| Mavronasiou, E | 1 |
| Damelou, A | 1 |
| Xanthopoulou, I | 2 |
| Gizas, V | 1 |
| Raptis, G | 1 |
| Hahalis, G | 1 |
| Alexopoulos, D | 2 |
| Anselmi, A | 1 |
| Corbineau, H | 1 |
| Boulmier, D | 1 |
| Ruggieri, VG | 1 |
| Lara, DA | 1 |
| Olive, MK | 1 |
| George, JF | 1 |
| Brown, RN | 1 |
| Carlo, WF | 1 |
| Colvin, EV | 1 |
| Steenwyck, BL | 1 |
| Pearce, FB | 1 |
| Miao, Q | 1 |
| Wang, Q | 1 |
| Dong, L | 1 |
| Wang, Y | 2 |
| Tan, Y | 1 |
| Zhang, X | 1 |
| Currie, KD | 1 |
| McKelvie, RS | 1 |
| Macdonald, MJ | 1 |
| Kurtoğlu Gümüşel, H | 1 |
| Çatakoğlu, AB | 1 |
| Yıldırımtürk, Ö | 1 |
| Yurdakul, S | 1 |
| Helvacıoğlu, F | 1 |
| Ziyrek, M | 1 |
| Hanavdeloğulları, R | 1 |
| Aytekin, V | 1 |
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| Wang, X | 1 |
| Zeng, C | 1 |
| Gong, H | 1 |
| He, H | 1 |
| Wang, M | 1 |
| Hu, Q | 1 |
| Yang, F | 1 |
| Dharma, S | 1 |
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| Patel, T | 1 |
| Kiemeneij, F | 1 |
| Gilchrist, IC | 1 |
| Chandrasekhar, J | 1 |
| Mehran, R | 1 |
| Giuseppe, C | 1 |
| Paul, J | 1 |
| Hans-Ulrich, I | 1 |
| Mitsutake, Y | 1 |
| Ueno, T | 1 |
| Ikeno, F | 1 |
| Yokoyama, S | 1 |
| Sasaki, K | 1 |
| Nakayoshi, T | 1 |
| Itaya, N | 1 |
| Chibana, H | 1 |
| Sasaki, M | 1 |
| Fukumoto, Y | 1 |
| Suh, YJ | 1 |
| Hong, YJ | 1 |
| Lee, HJ | 1 |
| Hur, J | 1 |
| Kim, YJ | 3 |
| Lee, HS | 1 |
| Hong, SR | 1 |
| Im, DJ | 1 |
| Park, CH | 1 |
| Kim, TH | 1 |
| Yoo, KJ | 1 |
| Choi, BW | 1 |
| Maruhashi, T | 1 |
| Kajikawa, M | 1 |
| Nakashima, A | 1 |
| Iwamoto, Y | 1 |
| Iwamoto, A | 1 |
| Oda, N | 1 |
| Kishimoto, S | 1 |
| Matsui, S | 1 |
| Higaki, T | 1 |
| Shimonaga, T | 1 |
| Watanabe, N | 1 |
| Ikenaga, H | 1 |
| Hidaka, T | 1 |
| Kihara, Y | 1 |
| Chayama, K | 2 |
| Goto, C | 1 |
| Aibara, Y | 1 |
| Noma, K | 2 |
| Higashi, Y | 2 |
| Pare, JR | 1 |
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| Moore, CL | 1 |
| Safdar, B | 1 |
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| Yamamoto, T | 1 |
| Takahashi, M | 1 |
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| Noike, H | 1 |
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| Mahjoob, MP | 1 |
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| Khaheshi, I | 1 |
| Akbarzadeh, MA | 1 |
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| Wittfeldt, A | 1 |
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| Kim, NH | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Register Kardialer Computertomographie[NCT03815123] | 10,000 participants (Anticipated) | Observational [Patient Registry] | 2018-12-06 | Recruiting | |||
| A Phase 4, Randomized, Double-Blind, Placebo-Controlled, Parallel Study of Ranolazine in Subjects With Chronic Stable Angina and Coronary Artery Disease With a History of Type 2 Diabetes Mellitus[NCT01425359] | Phase 4 | 949 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| Does Ranolazine Decrease Biomarkers That Indicate Evidence of Myocardial Damage in Diabetics With Stable Ischemic Heart Disease? A Double-blinded, Randomized, Placebo Controlled Trial[NCT02611596] | 0 participants (Actual) | Interventional | 2016-11-30 | Withdrawn | |||
| A Randomized Comparison of Post-procedural/Pre-hemostasis Intraarterial Nitroglycerin Versus Nicardipine to Reduce Radial Artery Occlusion After Transradial Catheterization[NCT03622060] | Phase 3 | 600 participants (Actual) | Interventional | 2018-06-04 | Completed | ||
| Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).[NCT02350439] | Phase 3 | 30 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Assessment of a Peripheral Endothelial Dysfunction in COPD (Chronic Obstructive Pulmonary Disease)[NCT02593357] | 137 participants (Actual) | Interventional | 2012-12-17 | Completed | |||
| Peripheral Endothelial Function in Asthmatic Patients[NCT02593344] | 113 participants (Actual) | Interventional | 2012-12-13 | Completed | |||
| The Effects of Exercise Training on Tumor Vascularity and Response to Neoadjuvant Therapy in Operable Breast Cancer: A Phase I-II Study[NCT00405678] | Phase 1/Phase 2 | 23 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| [NCT00000554] | Phase 3 | 0 participants | Interventional | 2001-05-31 | Completed | ||
| Non-invasive Fractional Flow Reserve CT (FFRCT) Scan for the Study of Coronary Vaso-motion[NCT02809157] | 10 participants (Anticipated) | Observational | 2014-10-31 | Active, not recruiting | |||
| The Effects of Traditional Acupuncture on Mechanisms of Coronary Heart Disease[NCT00570024] | 145 participants (Actual) | Interventional | 2006-01-31 | Completed | |||
| WISE Ancillary Study Data Analyses: Efficacy of Hormone Replacement on Myocardial Ischemia in Postmenopausal Women With Normal/Minimal Coronary Artery Disease: Data Analysis[NCT00600106] | 37 participants (Actual) | Interventional | 1999-12-31 | Completed | |||
| Randomized, Double-Blind, Active-Controlled, Multicenter Trial of Abciximab And Bivalirudin in Patients With Non-ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Interventions (ISAR-REACT-4)[NCT00373451] | Phase 4 | 1,721 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
| Randomized-controlled Trial to Assess the Effects of Different Trans-fatty Acids on Endothelial Function in Humans[NCT00933322] | 142 participants (Actual) | Interventional | 2009-07-31 | Terminated (stopped due to Recruitment problems) | |||
| Pilot Study of Telmisartan (Micardis) For the Prevention of Acute Graft vs. Host Disease Post Allogeneic Hematopoietic Stem Cell Transplantation[NCT02338232] | 32 participants (Actual) | Interventional | 2015-07-07 | Terminated (stopped due to Lack of Accrual) | |||
| Treatment of Slow-flow After Primary Percutaneous Coronary Intervention With Flow-mediated Hyperemia[NCT04685941] | 67 participants (Actual) | Interventional | 2021-01-25 | Completed | |||
| Do Innovative Strategies Complement Medical Management to Reduce Cardiovascular Risk Factors Following Coronary Artery Bypass Graft Surgery?[NCT00462436] | Phase 2 | 35 participants (Anticipated) | Interventional | 2007-02-28 | Completed | ||
| Comprehensive Treatment of Angina in Women With Microvascular Dysfunction - a Proof of Concept Study of the iPower Cohort[NCT02910154] | 62 participants (Actual) | Interventional | 2016-12-31 | Completed | |||
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| Single-centre, Single-blind, Randomized, Controlled, Cross-over Study to Analyze the Influence of Nitric Oxide on Flow Mediated Dilation[NCT03723278] | 20 participants (Actual) | Observational | 2018-11-14 | Completed | |||
| Effects of Exercise Training on Vascular Endothelial Function of Patients Submitted to Coronary Artery Bypass Graft[NCT02265107] | 9 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women[NCT00666172] | Phase 2 | 270 participants (Actual) | Interventional | 2008-04-08 | Completed | ||
| Evaluation of the Efficacy of Natural Senolytic Agents and NLRP3 Inhibitors in Treatment of Osteoarthritis: Randomized, Double Blinded ,Placebo Controlled Trial[NCT05276895] | 60 participants (Anticipated) | Interventional | 2022-07-01 | Suspended (stopped due to unavailability of drugs) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Average weekly angina frequency was defined as the total number of angina episodes reported during the last 6 weeks of treatment divided by 6 weeks.~For subjects who terminated with less than 6 weeks of treatment, frequency was calculated as the total number of angina episodes reported during the treatment period divided by the subject's actual duration of treatment." (NCT01425359)
Timeframe: 6 weeks
| Intervention | angina attacks per week (Mean) |
|---|---|
| Placebo | 5.2 |
| Ranolazine | 4.5 |
Average weekly frequency of sublingual nitroglycerin use was defined as the total number reported during the last 6 weeks of treatment divided by the duration corresponding to the last 6 weeks of treatment. (NCT01425359)
Timeframe: 6 weeks
| Intervention | nitroglycerin uses per week (Mean) |
|---|---|
| Placebo | 3.6 |
| Ranolazine | 2.9 |
The PGIC was completed at the end of treatment/last visit.The PGIC scale measures the change in the participant's overall status since the beginning of the study on a scale ranging from 1 (no change or worse) to 7 (very much improved). (NCT01425359)
Timeframe: 8 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 3.9 |
| Ranolazine | 4.0 |
(NCT01425359)
Timeframe: 6 weeks
| Intervention | percentage of weeks (Mean) |
|---|---|
| Placebo | 50 |
| Ranolazine | 54 |
For each participant, the percentage of the last 6 weeks on treatment during which the angina frequency was less than or equal to 50% of the baseline average weekly angina frequency was determined. (NCT01425359)
Timeframe: 6 weeks
| Intervention | percentage of weeks (Mean) |
|---|---|
| Placebo | 41 |
| Ranolazine | 46 |
The range of each health domain score is 0-100, with 0 indicating a poorer health state and 100 indicating a better health state. An increase in score indicates an improvement in health state. Participants were asked to complete the survey at randomization (prior to receiving treatment), and at end of treatment visit (Week 8) or early study drug discontinuation or early termination visit. The survey asked participants for responses specific to the preceding 4 weeks prior to completing the survey. (NCT01425359)
Timeframe: Up to 8 weeks
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Mental Component Score | Physical Component Score | |
| Placebo | 1.2 | 1.9 |
| Qualifying Phase: Participants Entered a 2-week Washout Period | 1.0 | 2.8 |
"Endothelial dysfunction refers to altered vasoactive, anticoagulant, and anti-inflammatory properties of endothelium, and dysregulated vascular growth remodeling that results from a loss of nitric oxide (NO) bioactivity in the endothelium. Brachial Artery Reactivity Testing (BART), high-frequency ultrasonographic imaging of the brachial artery, evaluates flow-mediated vasodilation (FMD), an endothelium-dependent function. The technique provokes the release of nitric oxide, resulting in vasodilation that can be quantitated as an index of endothelial dysfunction.~Flow-mediated vasodilation is typically expressed as the change in post-stimulus diameter as a percentage of the baseline diameter [diameter after cuff deflation - baseline diameter / baseline diameter) x 100]." (NCT00600106)
Timeframe: Baseline
| Intervention | percentage of pre-stimulus diameter (Mean) |
|---|---|
| Hormone Replacement Therapy | 8.2 |
| Placebo | 8.8 |
"Endothelial dysfunction refers to altered vasoactive, anticoagulant, and anti-inflammatory properties of endothelium, and dysregulated vascular growth remodeling that results from a loss of nitric oxide (NO) bioactivity in the endothelium. Brachial Artery Reactivity Testing (BART), high-frequency ultrasonographic imaging of the brachial artery, evaluates flow-mediated vasodilation (FMD), an endothelium-dependent function. The technique provokes the release of nitric oxide, resulting in vasodilation that can be quantitated as an index of vasomotor function.~Flow-mediated vasodilation is typically expressed as the change in post-stimulus diameter as a percentage of the baseline diameter [diameter after cuff deflation - baseline diameter / baseline diameter) x 100]." (NCT00600106)
Timeframe: 12 weeks
| Intervention | percentage of pre-stimulus diameter (Mean) |
|---|---|
| Hormone Replacement Therapy | 8.8 |
| Placebo | 7.3 |
Inducible myocardial ischemia measured by P-31 gated magnetic resonance cardiac spectroscopy (MRS) is reported as change (∆) in PCr/ATP ratio, with isometric submaximal handgrip stress. PCr/ATP ratio defined as (stress-[average of rest and recovery periods]) / average of rest and recover periods X 100, and expressed as % mean ± SD. For this trial, myocardial ischemia was pre-specified as a fall in quantitative PCR/ATP ratio >20% from rest, and a lower value is considered indicative of greater ischemia. (NCT00600106)
Timeframe: 12 weeks
| Intervention | percent change in PCR/ATP ratio (Mean) |
|---|---|
| Hormone Replacement Therapy | -7.7 |
| Placebo | 1.1 |
Inducible myocardial ischemia measured by P-31 gated magnetic resonance cardiac spectroscopy (MRS) is reported as change (∆) in PCr/ATP ratio, with isometric submaximal handgrip stress. PCr/ATP ratio defined as (stress-[average of rest and recovery periods]) / average of rest and recover periods X 100, and expressed as % mean ± SD. For this trial, myocardial ischemia was pre-specified as a fall in quantitative PCR/ATP ratio >20% from rest, and a lower value is considered indicative of greater ischemia. (NCT00600106)
Timeframe: Baseline
| Intervention | percent changed in PCR/ATP ratio (Mean) |
|---|---|
| Hormone Replacement Therapy | -13.8 |
| Placebo | -7.0 |
"Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain.~In electrocardiography, the ST segment connects the QRS complex and the T wave and has duration of 80 to 120 ms. It should be essentially level with the PR and TP segment. The normal ST segment has a slight upward concavity. Flat, downsloping, or depressed ST segment may indicate coronary ishcemia. Positive treadmill exercise stress test (>1.0 mm horizontal / downsloping or >1.5 upsloping ST segment depression measured 0.08 msec after the J point)." (NCT00600106)
Timeframe: Baseline
| Intervention | mm (Mean) |
|---|---|
| Hormone Replacement Therapy | -0.79 |
| Placebo | -0.79 |
Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. (NCT00600106)
Timeframe: Baseline
| Intervention | metabolism equivalents (Mean) |
|---|---|
| Hormone Replacement Therapy | 6.1 |
| Placebo | 5.8 |
Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. (NCT00600106)
Timeframe: Exit (12 weeks)
| Intervention | metabolism equivalents (Mean) |
|---|---|
| Hormone Replacement Therapy | 6.1 |
| Placebo | 5.4 |
Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. A MET is defined as the resting metabolic rate, that is, the amount or oxygen consumet at rest, sitting quietly in a chair, approximately 3.5 ml O2 / kg / min (1.2 kcallmin for a 70-kg person). As such, work at METs requires twice the resting metabolism or 7.0 ml O2/kg/min, and so on. (NCT00600106)
Timeframe: Baseline
| Intervention | metabolism equivalents (Mean) |
|---|---|
| Hormone Replacement Therapy | 5.4 |
| Placebo | 5.4 |
Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain. A MET is defined as the resting metabolic rate, that is, the amount or oxygen consumet at rest, sitting quietly in a chair, approximately 3.5 ml O2 / kg / min (1.2 kcallmin for a 70-kg person). As such, work at METs requires twice the resting metabolism or 7.0 ml O2/kg/min, and so on. (NCT00600106)
Timeframe: Exit at 12 weeks
| Intervention | metabolism equivalents (Mean) |
|---|---|
| Hormone Replacement Therapy | 6.1 |
| Placebo | 5.4 |
"Physical functional disability measured by exercise stress testing. Functional capacity was measured as metabolism equivalents (METs), exercise duration, and exercise-induced chest pain.~In electrocardiography, the ST segment connects the QRS complex and the T wave and has duration of 80 to 120 ms. It should be essentially level with the PR and TP segment. The normal ST segment has a slight upward concavity. Flat, downsloping, or depressed ST segment may indicate coronary ishcemia. Positive treadmill exercise stress test (>1.0 mm horizontal / downsloping or >1.5 upsloping ST segment depression measured 0.08 msec after the J point)." (NCT00600106)
Timeframe: Exit (12 weeks)
| Intervention | mm (Mean) |
|---|---|
| Hormone Replacement Therapy | -1.05 |
| Placebo | -0.63 |
"Quality of life assessed by cardiac symptoms and psychological questionnaires (SF 36 scale - Short Form Health Survey) The SF-36 includes one multi-item scale that assesses eight health concepts: 1) limitations in physical activities because of health problems; 2) limitations in social activities because of physical or emotional problems; 3) limitations in usual role activities because of physical health problems; 4) bodily pain; 5) general mental health (psychological distress and well-being); 6) limitations in usual role activities because of emotional problems; 7) vitality (energy and fatigue); and 8) general health perceptions.~Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability." (NCT00600106)
Timeframe: 12 weeks
| Intervention | units on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| Physical functioning | Role-physical | Role-emotional | Bodily pain | General health | Mental health | Vitality | Social functioning | |
| Hormone Replacement Therapy | 59.4 | 58.8 | 76.5 | 54.5 | 55.2 | 66.4 | 35.6 | 59.4 |
| Placebo | 44.4 | 25.0 | 66.7 | 41.5 | 57.2 | 69.3 | 41.2 | 56.1 |
"Quality of life assessed by cardiac symptoms and psychological questionnaires (SF 36 scale - Short Form Health Survey) The SF-36 includes one multi-item scale that assesses eight health concepts: 1) limitations in physical activities because of health problems; 2) limitations in social activities because of physical or emotional problems; 3) limitations in usual role activities because of physical health problems; 4) bodily pain; 5) general mental health (psychological distress and well-being); 6) limitations in usual role activities because of emotional problems; 7) vitality (energy and fatigue); and 8) general health perceptions.~Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability." (NCT00600106)
Timeframe: Baseline
| Intervention | units on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| Physical functioning | Role-physical | Role-emotional | Bodily pain | General health | Mental health | Vitality | Social functioning | |
| Hormone Replacement Therapy | 60.8 | 54.2 | 70.3 | 53.3 | 55.4 | 66.7 | 35.6 | 59.4 |
| Placebo | 43.8 | 37.3 | 66.7 | 42.1 | 57.4 | 65.7 | 42.9 | 53.2 |
Quality of life assessed by menopausal symptoms and psychological questionnaires (NCT00600106)
Timeframe: 12 weeks
| Intervention | percent of participants (Number) | ||||
|---|---|---|---|---|---|
| Hot flushes or flashing | Poor memory | Change in sexual desire | Vaginal dryness | Avoiding intimacy | |
| Hormone Replacement Therapy | 41 | 59 | 35 | 35 | 24 |
| Placebo | 89 | 78 | 67 | 67 | 56 |
Quality of life assessed by menopausal symptoms and psychological questionnaires (NCT00600106)
Timeframe: Baseline
| Intervention | percent of participants (Number) | ||||
|---|---|---|---|---|---|
| Hot flushes or flashing | Poor memory | Change in sexual desire | Vaginal dryness | Avoiding intimacy | |
| Hormone Replacement Therapy | 89 | 76 | 50 | 44 | 39 |
| Placebo | 68 | 53 | 37 | 58 | 37 |
12 reviews available for nitroglycerin and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Cardiac Rehabilitation Improves Endothelial Function in Coronary Artery Disease Patients.
Topics: Brachial Artery; Cardiac Rehabilitation; Coronary Artery Disease; Endothelium, Vascular; Humans; Nit | 2022 |
Use of nitrates in ischemic heart disease.
Topics: Angina Pectoris; Coronary Artery Disease; Delayed-Action Preparations; Drug Tolerance; Humans; Myoca | 2015 |
Organic nitrates and nitrate tolerance--state of the art and future developments.
Topics: Animals; Coronary Artery Disease; Drug Tolerance; Humans; Nitrates; Nitroglycerin; Vasodilation; Vas | 2010 |
Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic review.
Topics: Chest Pain; Coronary Artery Disease; Humans; Nitroglycerin; Sensitivity and Specificity; Vasodilator | 2012 |
New methods to evaluate endothelial function: Non-invasive method of evaluating endothelial function in humans.
Topics: Brachial Artery; Clinical Trials as Topic; Coronary Artery Disease; Endothelium, Vascular; Estrogen | 2003 |
[Risk management of coronary artery disease--pharmacological therapy].
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Arte | 2004 |
Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Ar | 2005 |
Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Ar | 2005 |
Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Ar | 2005 |
Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Ar | 2005 |
Assessment of vascular disease using arterial flow mediated dilatation.
Topics: Arteries; Coronary Artery Disease; Diagnostic Techniques, Cardiovascular; Endothelium, Vascular; Hum | 2006 |
[Organic angina].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Calcium C | 2007 |
[Diagnosis of the dynamic lesion].
Topics: Acetylcholine; Angina Pectoris, Variant; Angina, Unstable; Coronary Angiography; Coronary Artery Dis | 1993 |
[Endogenous and therapeutic nitrates in healthy and arteriosclerotic blood vessels].
Topics: Animals; Coronary Artery Disease; Endothelium, Vascular; Free Radicals; Humans; Nitrates; Nitric Oxi | 1993 |
[Nitrate derivatives and coronary vasomotricity].
Topics: Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Humans; Isosorbide Dinitrate; Nitrogl | 1992 |
44 trials available for nitroglycerin and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
A mix of aminophylline and heparin plus nitroglycerin can reduce bradycardia during rotational atherectomy on the right coronary artery and dominant circumflex artery.
Topics: Aminophylline; Atherectomy, Coronary; Atrioventricular Block; Bradycardia; Coronary Angiography; Cor | 2023 |
Vasomotor Response to Nitroglycerine Over 5 Years Follow-Up After Everolimus-Eluting Bioresorbable Scaffold Implantation.
Topics: Absorbable Implants; Cardiovascular Agents; Coated Materials, Biocompatible; Coronary Angiography; C | 2017 |
Effect of the ratio of coronary arterial lumen volume to left ventricle myocardial mass derived from coronary CT angiography on fractional flow reserve.
Topics: Aged; Area Under Curve; Cardiac Catheterization; Chi-Square Distribution; Computed Tomography Angiog | 2017 |
Evaluation of human coronary vasodilator function predicts future coronary atheroma progression.
Topics: Aged; Albuterol; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Disease Progressio | 2018 |
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).
Topics: Acetanilides; Aged; Angina, Stable; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind | 2013 |
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).
Topics: Acetanilides; Aged; Angina, Stable; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind | 2013 |
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).
Topics: Acetanilides; Aged; Angina, Stable; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind | 2013 |
Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).
Topics: Acetanilides; Aged; Angina, Stable; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind | 2013 |
Platelet inhibition by IV glyceryl trinitrate in patients with stable coronary artery disease on dual antiplatelet therapy subjected to PCI.
Topics: Blood Platelets; Combined Modality Therapy; Coronary Artery Disease; Female; Humans; Infusions, Intr | 2013 |
Brachial artery endothelial responses during early recovery from an exercise bout in patients with coronary artery disease.
Topics: Aged; Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Exercise; Humans; Male; Middl | 2014 |
A novel approach to reduce radial artery occlusion after transradial catheterization: postprocedural/prehemostasis intra-arterial nitroglycerin.
Topics: Angiography; Arterial Occlusive Diseases; Coronary Artery Disease; Female; Follow-Up Studies; Humans | 2015 |
The Assessment of short-term effect of L-Citrulline on endothelial function via FMD to NMD ratio in known CAD patients: A randomized, cross-over clinical trial (Clinical trial number: NCT02638727).
Topics: Aged; Brachial Artery; Citrulline; Coronary Artery Disease; Cross-Over Studies; Endothelium, Vascula | 2017 |
Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study.
Topics: Administration, Oral; Aged; Biomarkers; Blood Glucose; Brachial Artery; Cell Adhesion Molecules; Cho | 2009 |
The effect of statin therapy on stimulation of endothelium-derived nitric oxide before and after coronary artery bypass surgery.
Topics: Aged; Atorvastatin; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Disease; Female; | 2010 |
[Experimental study on the option of antispasmodic drugs for radial artery in elderly patients with coronary atherosclerotic heart disease].
Topics: Aged; Aged, 80 and over; Coronary Artery Bypass; Coronary Artery Disease; Diltiazem; Female; Follow- | 2010 |
Nitroglycerin cardioplegia effect on coronary artery targets in bypass grafting.
Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Coronary Angiography; Coronary Artery Bypas | 2011 |
Peroperative effects of fresh frozen plasma and antithrombin III on heparin sensitivity and coagulation during nitroglycerine infusion in coronary artery bypass surgery.
Topics: Aged; Anticoagulants; Antithrombin III; Blood Coagulation; Coronary Artery Bypass; Coronary Artery D | 2011 |
Direct intramyocardial mesenchymal stromal cell injections in patients with severe refractory angina: one-year follow-up.
Topics: Aged; Angina Pectoris; Bone Marrow Cells; Cells, Cultured; Coronary Artery Disease; Exercise Test; F | 2013 |
Assessment of endothelial function using peripheral waveform analysis: a clinical application.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Body Mass Index; Coronary Artery Disease | 2002 |
Assessment of endothelial function using peripheral waveform analysis: a clinical application.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Body Mass Index; Coronary Artery Disease | 2002 |
Assessment of endothelial function using peripheral waveform analysis: a clinical application.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Body Mass Index; Coronary Artery Disease | 2002 |
Assessment of endothelial function using peripheral waveform analysis: a clinical application.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Blood Pressure; Body Mass Index; Coronary Artery Disease | 2002 |
Effect of cardiac cycle on ultrasound assessment of endothelial function.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Brachial Artery; Coronary Artery Disease; Diagnostic E | 2002 |
Effect of atorvastatin on endothelium-dependent vasodilation in patients with coronary artery disease.
Topics: Aged; Atorvastatin; Blood Flow Velocity; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Coronar | 2003 |
Efficacy of transdermal nitroglycerin patches evaluated by dipyridamole-induced myocardial ischemia in patients with coronary artery disease. Comparison between continuous and intermittent schedule.
Topics: Administration, Cutaneous; Aged; Coronary Artery Disease; Cross-Over Studies; Dipyridamole; Double-B | 2002 |
Exercise training improves conduit vessel function in patients with coronary artery disease.
Topics: Brachial Artery; Coronary Artery Disease; Coronary Circulation; Cross-Over Studies; Endothelium, Vas | 2003 |
The influence of nitroglycerin on myocardial 99mTc-Tetrofosmin uptake defects in coronary artery disease.
Topics: Adult; Aged; Coronary Angiography; Coronary Artery Disease; Female; Heart Ventricles; Humans; Image | 2002 |
[Selective COX-2 inhibition improves endothelial function in coronary artery disease].
Topics: Aged; Arteries; Celecoxib; Coronary Artery Disease; Coronary Vessels; Cyclooxygenase 2; Endothelium- | 2003 |
Technetium-99m-tetrofosmin imaging with incremental nitroglycerin infusion to detect severely ischaemic but viable myocardium: a comparative study with thallium-201.
Topics: Adult; Aged; Coronary Artery Disease; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myo | 2003 |
The effect of rapid decreases of blood pressure by different mechanisms on coronary flow and flow reserve in normal coronary arteries.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Clonidine; Coronary Artery Disea | 2003 |
Gene therapy of coronary artery disease with phvegf165--early outcome.
Topics: Aged; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Circulation; F | 2003 |
Delayed preconditioning-mimetic actions of nitroglycerin in patients undergoing exercise tolerance tests.
Topics: Aged; Coronary Artery Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Me | 2005 |
Selective COX-2 inhibition with different doses of rofecoxib does not impair endothelial function in patients with coronary artery disease.
Topics: Aged; Brachial Artery; Coronary Artery Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclo | 2005 |
The effect of tadalafil on the time to exercise-induced myocardial ischaemia in subjects with coronary artery disease.
Topics: Aged; Analysis of Variance; Blood Pressure; Carbolines; Coronary Artery Disease; Cross-Over Studies; | 2005 |
Comparison of antihypertensives after coronary artery surgery.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Corona | 2005 |
Large and small vessel vasoconstriction following coronary artery stenting. Effect of intra coronary nitroglycerine and relation to LDL cholesterol.
Topics: Aged; Angioplasty, Balloon, Coronary; Cholesterol, LDL; Coronary Artery Disease; Coronary Circulatio | 2006 |
Assessment of coronary vasodilatation in response to nitroglycerin with transthoracic Doppler echocardiography.
Topics: Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Echocardiograp | 2006 |
Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Brachial Artery; Coronary Artery Disease; Cross | 2006 |
The relationship between aortic augmentation index and pulse wave velocity: an invasive study.
Topics: Adult; Aged; Aorta; Blood Pressure Determination; Cardiac Catheterization; Coronary Artery Disease; | 2007 |
Comparative predictive and diagnostic value of flow-mediated vasodilation in the brachial artery and intima media thickness of the carotid artery for assessment of coronary artery disease severity.
Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Carotid Stenosis; Coronary Artery Disease; Electroc | 2007 |
Noninvasive assessment of coronary vasodilating capacity using freehand 3-dimensional echocardiography with rotational scanning.
Topics: Coronary Artery Disease; Coronary Vessels; Echocardiography, Three-Dimensional; Female; Humans; Imag | 2007 |
The effect of large unilamellar vesicles on vascular function in patients with coronary atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cholesterol; Coronary Artery Disease; Endot | 2008 |
Comparison of effect between nitrates and calcium channel antagonist on vascular function in patients with normal or mildly diseased coronary arteries.
Topics: Acetylcholine; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Arter | 2008 |
Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease.
Topics: Acetylcholine; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Endot | 1995 |
Plasma alpha-tocopherol and coronary endothelium-dependent vasodilator function.
Topics: Acetylcholine; Cholesterol; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Female | 1999 |
The impact of risk factors for atherosclerosis on the vasomotor effects of inhibition of nitric oxide synthesis in patients with normal angiograms.
Topics: Aged; Analysis of Variance; Coronary Angiography; Coronary Artery Disease; Endothelium, Vascular; Fe | 2000 |
High-dose intravascular beta-radiation after de novo stent implantation induces coronary artery spasm.
Topics: Animals; Beta Particles; Blood Vessel Prosthesis Implantation; Brachytherapy; Catheterization; Coron | 2002 |
Effect of exercise on upper and lower extremity endothelial function in patients with coronary artery disease.
Topics: Arm; Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Exercise; Exercise Tolerance; | 2002 |
Alleviation of cocaine-induced coronary vasoconstriction by nitroglycerin.
Topics: Administration, Intranasal; Administration, Sublingual; Aged; Cardiac Catheterization; Cocaine; Coro | 1991 |
Intravenous diltiazem versus nitroglycerin for silent and symptomatic myocardial ischemia in unstable angina pectoris.
Topics: Aged; Angina, Unstable; Coronary Angiography; Coronary Artery Disease; Diltiazem; Electrocardiograph | 1991 |
125 other studies available for nitroglycerin and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Factors influencing the safety of outpatient coronary CT angiography: a clinical registry study.
Topics: Aged; Computed Tomography Angiography; Coronary Angiography; Coronary Artery Disease; Humans; Male; | 2022 |
Clinical Outcomes of Cardiac Shockwave Therapy in Severe Coronary Artery Disease Patients after Coronary Artery Bypass Grafting.
Topics: Canada; Coronary Artery Bypass; Coronary Artery Disease; High-Energy Shock Waves; Humans; Nitroglyce | 2023 |
Can Significant Coronary Artery Disease Coexist With Transient Takotsubo Cardiomyopathy, and How Does Spasm Interrelate?
Topics: Aged, 80 and over; Coronary Angiography; Coronary Artery Disease; Electrocardiography; Female; Human | 2023 |
Questionable necessity of nitroglycerin for diagnostic coronary artery examination using 320-row multi-detector computed tomography.
Topics: Administration, Sublingual; Adult; Aged; Computed Tomography Angiography; Coronary Angiography; Coro | 2020 |
Unrecognized coronary vasospasm in patients referred for percutaneous coronary intervention: Intracoronary nitroglycerin, the forgotten stepchild of cardiovascular guidelines.
Topics: Clinical Decision-Making; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary | 2017 |
Nitroglycerin-Derived Pd/Pa for the Assessment of Intermediate Coronary Lesions.
Topics: Adenosine; Aged; Comparative Effectiveness Research; Coronary Angiography; Coronary Artery Disease; | 2017 |
Responsiveness of internal thoracic arteries to nitroglycerin in patients with renal failure.
Topics: Aged; Coronary Artery Bypass; Coronary Artery Disease; Female; Glomerular Filtration Rate; Humans; I | 2018 |
Comparison of serum levels of IL-6, IL-8, TGF-β and TNF-α in coronary artery diseases, stable angina and participants with normal coronary artery.
Topics: Angina, Stable; Case-Control Studies; Coronary Artery Disease; Coronary Vessels; Cross-Sectional Stu | 2018 |
Poor Compliance With Carrying Nitroglycerin and Aspirin in Patients With Coronary Artery Disease.
Topics: Aged; Aged, 80 and over; Aspirin; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans | 2018 |
Impact of sublingual nitroglycerin dosage on FFR
Topics: Administration, Sublingual; Computed Tomography Angiography; Coronary Angiography; Coronary Artery D | 2019 |
Peripheral artery disease is associated with severe impairment of vascular function.
Topics: Aged; Blood Flow Velocity; Blood Vessels; Brachial Artery; Comorbidity; Coronary Artery Disease; End | 2013 |
Early diffuse coronary artery spasm after heart valve surgery in the carcinoid syndrome.
Topics: Aged; Carcinoid Heart Disease; Coronary Angiography; Coronary Artery Disease; Heart Failure; Humans; | 2013 |
Systemic effects of intracoronary nitroglycerin during coronary angiography in children after heart transplantation.
Topics: Adolescent; Age Factors; Blood Pressure; Child; Child, Preschool; Coronary Angiography; Coronary Art | 2014 |
The expression of p66shc in peripheral blood monocytes is increased in patients with coronary heart disease and correlated with endothelium-dependent vasodilatation.
Topics: Aged; Brachial Artery; Case-Control Studies; Coronary Artery Disease; Endothelium, Vascular; Female; | 2015 |
Relationship between endothelial dysfunction and cardiovascular risk factors and the extent and severity of coronary artery disease.
Topics: Blood Flow Velocity; Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Female; Humans | 2014 |
The influence of nitroglycerin on the proliferation of endothelial progenitor cells from peripheral blood of patients with coronary artery disease.
Topics: Cell Proliferation; Cells, Cultured; Coronary Artery Disease; Culture Media; Endothelial Progenitor | 2014 |
Radial artery occlusion: preventing insult to injury.
Topics: Arterial Occlusive Diseases; Coronary Artery Disease; Female; Humans; Male; Nitroglycerin; Percutane | 2015 |
Serial changes of coronary endothelial function and arterial healing after paclitaxel-eluting stent implantation.
Topics: Acetylcholine; Aged; Angina, Stable; Angioscopy; Coronary Angiography; Coronary Artery Disease; Coro | 2016 |
Prognostic value of SYNTAX score based on coronary computed tomography angiography.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Coronary Angiography; Coronary Artery Disease; Female; | 2015 |
Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Coronary Angiography; Coronary Artery Disease; Coro | 2016 |
Corrected flow time: a noninvasive ultrasound measure to detect preload reduction by nitroglycerin.
Topics: Administration, Sublingual; Blood Flow Velocity; Blood Volume; Brachial Artery; Coronary Artery Dise | 2016 |
Effect of nitroglycerin administration on cardio-ankle vascular index.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Analysis of Variance; Ankle; Aorta; Bloo | 2016 |
Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation.
Topics: Adenosine; Adolescent; Adult; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Co | 2016 |
Effect of High (200 μg/kg per Minute) Adenosine Dose Infusion on Fractional Flow Reserve Variability.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Arterial Pressure; Coronary Angiography; Coronary Artery D | 2016 |
Impact of vasomotion type on prognosis of coronary artery spasm induced by acetylcholine provocation test of left coronary artery.
Topics: Acetylcholine; Adult; Aged; Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Coronary | 2017 |
Cardiac arrest at high elevation with a favorable outcome.
Topics: Adult; Air Ambulances; Altitude; Aspirin; Computed Tomography Angiography; Coronary Angiography; Cor | 2017 |
Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease.
Topics: Blood Pressure; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus; Female; Heart Rate; Hu | 2008 |
Repolarization changes induced by mental stress in normal subjects and patients with coronary artery disease: effect of nitroglycerine.
Topics: Adult; Aged; Coronary Artery Disease; Electrocardiography; Female; Heart Rate; Heart Ventricles; Hum | 2009 |
The brachial artery remodels to maintain local shear stress despite the presence of cardiovascular risk factors.
Topics: Adaptation, Physiological; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Atherosclerosis; | 2009 |
Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification.
Topics: Aged; Calcinosis; Coronary Artery Disease; Female; Humans; Image Interpretation, Computer-Assisted; | 2008 |
Coronary artery function: out of the cath lab and into the magnet.
Topics: Calcinosis; Coronary Angiography; Coronary Artery Disease; Humans; Image Interpretation, Computer-As | 2008 |
Impact of introducer sheath coating on endothelial function in humans after transradial coronary procedures.
Topics: Adult; Aged; Catheterization; Coronary Artery Disease; Drug-Eluting Stents; Endothelium-Dependent Re | 2010 |
Coronary endothelial dysfunction is associated with a reduction in coronary artery compliance and an increase in wall shear stress.
Topics: Blood Flow Velocity; Compliance; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; En | 2010 |
Preclinical noninvasive markers of atherosclerosis in children and adolescents with type 1 diabetes are influenced by physical activity.
Topics: Adolescent; Biomarkers; Child; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus, | 2010 |
Cardiac shock wave therapy reduces angina and improves myocardial function in patients with refractory coronary artery disease.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; China; Coronary Artery Disease; Coronary Circ | 2010 |
Indications, imaging technique, and reading of cardiac computed tomography: survey of clinical practice.
Topics: Adrenergic beta-Antagonists; Cardiology; Coronary Angiography; Coronary Artery Disease; Health Care | 2012 |
[Frequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drug].
Topics: Administration, Sublingual; Angina Pectoris; Canada; Coronary Artery Disease; Drug Storage; Female; | 2011 |
Nitroglycerin-induced heterogeneous subendocardial myocardial blood flow observed by cardioscopy in patients with coronary artery disease.
Topics: Biopsy; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Endocardium; Endoscopy; Fem | 2011 |
[Frequency of sublingual nitroglycerin prescription in patients with coronary artery disease and angina and awareness of patients about the shelf life of the drug].
Topics: Administration, Sublingual; Angina Pectoris; Coronary Artery Disease; Humans; Nitroglycerin; Practic | 2011 |
[Comparative characteristics of revealing hibernated myocardium by means of perfusion and metabolic scintigraphy].
Topics: Coronary Artery Disease; Fatty Acids; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imagin | 2012 |
The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease.
Topics: Brachial Artery; Coronary Angiography; Coronary Artery Disease; Endothelium, Vascular; Ethnicity; Ge | 2002 |
Circulating autoantibodies to oxidized LDL correlate with impaired coronary endothelial function after cardiac transplantation.
Topics: Acetylcholine; Adult; Autoantibodies; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascul | 2002 |
Relation of vasodilator response of the brachial artery to inflammatory markers in patients with coronary artery disease.
Topics: Adult; Aged; Biomarkers; Blood Sedimentation; Brachial Artery; C-Reactive Protein; Cholesterol, HDL; | 2002 |
Impaired endothelial function in the brachial artery after Kawasaki disease and the effects of intravenous administration of vitamin C.
Topics: Adolescent; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Child; Child, Preschool; Coronary A | 2003 |
Vascular endothelial function in patients with slow coronary flow.
Topics: Adult; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Artery Disease; Coronary | 2003 |
Pressure wave reflection assessed from the peripheral pulse: is a transfer function necessary?
Topics: Adult; Aged; Aorta; Blood Pressure; Carotid Arteries; Coronary Artery Disease; Humans; Hypertension; | 2003 |
Prognostic value of nitrate enhanced Tc99m MIBI SPECT study in detecting viable myocardium in patients with coronary artery disease.
Topics: Coronary Artery Disease; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pro | 2003 |
Percutaneous interventions in radial artery grafts: clinical and angiographic outcomes.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enz | 2003 |
Von Willebrand factor in type 1 diabetes: its production and coronary artery calcification.
Topics: Adult; Albuminuria; Area Under Curve; Bradykinin; Calcinosis; Coronary Artery Disease; Diabetes Mell | 2003 |
Coronary vasomotor response is related to the angiographic extent of coronary sclerosis in patients with stable angina pectoris.
Topics: Acetylcholine; Aged; Analysis of Variance; Angina Pectoris; Chi-Square Distribution; Coronary Angiog | 2004 |
The effect of nitroglycerine on the ballistocardiogram of persons with and without clinical evidence of coronary heart disease.
Topics: Ballistocardiography; Coronary Artery Disease; Coronary Disease; Humans; Nitrites; Nitroglycerin | 1955 |
Sustained-action nitroglycerin (nitroglyn) in angina pectoris due to coronary sclerosis.
Topics: Angina Pectoris; Coronary Artery Disease; Nitrites; Nitroglycerin; Sclerosis | 1955 |
Haemodynamic consequences of coronary heart disease with observations during anginal pain and on the effect of nitroglycerine.
Topics: Angina Pectoris; Cardiac Catheterization; Catheterization; Coronary Artery Disease; Coronary Disease | 1958 |
Effect of nitroglycerin on the coronary circulation in patients with coronary artery disease or increased left ventricular work.
Topics: Coronary Artery Disease; Coronary Circulation; Coronary Disease; Coronary Vessels; Heart Diseases; H | 1959 |
[The effect of nitroglycerine on the cardiovascular system of patients with coronary heart disease].
Topics: Cardiotonic Agents; Cardiovascular System; Coronary Artery Disease; Coronary Disease; Nitrites; Nitr | 1960 |
Nitroglycerin and isosorbide dinitrate in coronary insufficiency.
Topics: Anti-Arrhythmia Agents; Cardiotonic Agents; Coronary Artery Disease; Coronary Disease; Isosorbide Di | 1961 |
[Recent observations on the value of nitroglycerin test for the diagnosis of coronary insufficiency].
Topics: Coronary Artery Disease; Coronary Disease; Humans; Nitrites; Nitroglycerin | 1959 |
[THE INFLUENCE OF NITROGLYCERIN ON THE MECHANICAL SYSTOLE IN CORONARY INSUFFICIENCY].
Topics: Coronary Artery Disease; Coronary Disease; Heart Function Tests; Humans; Nitroglycerin; Systole | 1963 |
[About listening the patient].
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Coronary Artery Disease; Female; Humans; Nitroglycer | 2003 |
Distal filter protection during percutaneous coronary intervention in native coronary arteries and saphenous vein grafts in patients with acute coronary syndromes.
Topics: Acute Disease; Aged; Angioplasty, Balloon, Coronary; Balloon Occlusion; Biomarkers; Blood Vessel Pro | 2003 |
Response of the left anterior descending coronary artery to acetylcholine in patients with chest pain and angiographically normal coronary arteries.
Topics: Acetylcholine; Blood Flow Velocity; Chest Pain; Cholesterol, LDL; Coronary Angiography; Coronary Art | 2003 |
Usefulness of attenuated heart rate recovery immediately after exercise to predict endothelial dysfunction in patients with suspected coronary artery disease.
Topics: Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Exercise Test; Female; Heart Rate; | 2004 |
Dobutamine-induced ST-segment elevation associated with a biphasic response of wall motion in patients with a recent myocardial infarction is caused by myocardial ischaemia and is abolished by revascularization of the infarct-related artery.
Topics: Adrenergic beta-Agonists; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Co | 2003 |
Ballistocardiographic response to nitroglycerin in coronary artery disease.
Topics: Coronary Artery Disease; Coronary Disease; Humans; Nitrites; Nitroglycerin | 1952 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).
Topics: Acetylcholine; Adenosine; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Co | 2004 |
Chest pain relief by nitroglycerin doesn't predict active coronary artery disease.
Topics: Angina Pectoris; Chest Pain; Cohort Studies; Coronary Artery Disease; Diagnosis, Differential; Emerg | 2004 |
Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy.
Topics: Acetylcholine; Aged; Blood Flow Velocity; Cardiac Volume; Coronary Angiography; Coronary Artery Dise | 2004 |
Lack of increased left main coronary artery dimensions in hypertensive patients with left ventricular hypertrophy and coronary artery disease. An intracoronary ultrasound study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Pressur | 2004 |
Antiplatelet therapy in non-ST-segment elevation acute coronary syndromes.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery B | 2004 |
[Is endothelial dysfunction of practical relevance?].
Topics: Acetylcholine; Arteriosclerosis; Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Hu | 2004 |
Noninvasive evaluation of endothelial function and arterial mechanics in overweight adolescents.
Topics: Adolescent; Age Factors; Body Mass Index; Brachial Artery; Carotid Artery, Common; Case-Control Stud | 2004 |
Severe coronary artery spasm can be associated with hyperthyroidism.
Topics: Angina, Unstable; Antithyroid Agents; Calcium Channel Blockers; Coronary Angiography; Coronary Arter | 2005 |
Relation of Basal coronary nitric oxide activity to the burden of atherosclerosis.
Topics: Adenosine; Blood Flow Velocity; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; | 2005 |
Endothelial dysfunction occurs in peripheral circulation patients with acute and stable coronary artery disease.
Topics: Acetylcholine; Acute Disease; Aged; C-Reactive Protein; Case-Control Studies; Chronic Disease; Coron | 2005 |
Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery.
Topics: Aged; Arm; Brachial Artery; Case-Control Studies; Coronary Artery Disease; Dilatation, Pathologic; F | 2006 |
Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia.
Topics: Acetylcholine; Adenosine; Aged; Arginine; Coronary Artery Disease; Endothelium, Vascular; Female; Hu | 2007 |
Brachial artery diameter and vasodilator response to nitroglycerine, but not flow-mediated dilatation, are associated with the presence and quantity of coronary artery calcium in asymptomatic adults.
Topics: Adult; Aged; Aged, 80 and over; Brachial Artery; Calcinosis; Calcium; Coronary Artery Disease; Coron | 2007 |
Impaired nitrate-mediated dilatation could reflect nitrate tolerance in patients with coronary artery disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brachial Artery; Case-Control Studies; Coronary Angiogr | 2007 |
Frequency of slow coronary flow following successful stent implantation and effect of Nitroprusside.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Angina Pectoris; Blood Vessel Prosthesis Implantation | 2007 |
Relationship between endothelial function and coronary risk factors in patients with stable coronary artery disease.
Topics: Administration, Sublingual; Aged; Aging; Brachial Artery; Coronary Artery Disease; Diabetic Angiopat | 2007 |
Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study.
Topics: Acetylcholine; Adenosine; Adult; Aged; Blood Flow Velocity; Coronary Angiography; Coronary Artery Di | 2007 |
Coronary endothelial dysfunction and hyperlipidemia are independently associated with diastolic dysfunction in humans.
Topics: Acetylcholine; Comorbidity; Coronary Artery Disease; Coronary Vessels; Echocardiography; Endothelium | 2007 |
Dislocation of the rotating cutter during directional coronary atherectomy: a note of caution.
Topics: Atherectomy, Coronary; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Equipment | 1995 |
Quantitative assessment of coronary vasoreactivity in humans in vivo. Importance of baseline vasomotor tone in atherosclerosis.
Topics: Acetylcholine; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Humans; Imag | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Close relation of endothelial function in the human coronary and peripheral circulations.
Topics: Acetylcholine; Adult; Aged; Brachial Artery; Cardiac Catheterization; Coronary Artery Disease; Coron | 1995 |
Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function.
Topics: Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary | 1995 |
[Role of occult atherosclerosis in coronary functions: study by intravascular ultrasound].
Topics: Angina Pectoris; Animals; Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Elasticity; | 1994 |
Assessment of coronary artery distensibility by intravascular ultrasound. Application of simultaneous measurements of luminal area and pressure.
Topics: Adult; Aged; Coronary Artery Disease; Coronary Vessels; Humans; Middle Aged; Nitroglycerin; Ultrason | 1995 |
Coronary reactivity to nitroglycerin: intravascular ultrasound evidence for the importance of plaque distribution.
Topics: Adult; Aged; Coronary Artery Disease; Coronary Vessels; Female; Humans; Injections, Intra-Arterial; | 1995 |
Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors.
Topics: Adolescent; Adult; Aged; Brachial Artery; Coronary Artery Disease; Endothelium, Vascular; Female; Fo | 1994 |
Determinants of coronary artery reactivity in premenopausal female cynomolgus monkeys with diet-induced atherosclerosis.
Topics: Acetylcholine; Animals; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Diet, Ather | 1994 |
Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis.
Topics: Acetylcholine; Adenosine; Blood Flow Velocity; Blood Pressure; Coronary Angiography; Coronary Artery | 1994 |
Safety of intracoronary ultrasound: data from a Multicenter European Registry.
Topics: Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Coronary Vasospasm; | 1996 |
Role of compensatory enlargement and shrinkage in transplant coronary artery disease. Serial intravascular ultrasound study.
Topics: Adult; Aged; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Fe | 1997 |
Effects of inhibition of nitric oxide synthesis in patients with coronary artery disease and stable angina.
Topics: Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Dose-Response | 1997 |
Effect of plaque burden on coronary vasoreactivity in early atherosclerosis.
Topics: Acetylcholine; Aged; Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Coronary Vessel | 1998 |
The correlation between coronary stenosis index and flow-mediated dilation of the brachial artery.
Topics: Adult; Aged; Angina, Unstable; Brachial Artery; Coronary Angiography; Coronary Artery Disease; Coron | 1998 |
Remodeling after directional coronary atherectomy (with and without adjunct percutaneous transluminal coronary angioplasty): a serial angiographic and intravascular ultrasound analysis from the Optimal Atherectomy Restenosis Study.
Topics: Anatomy, Cross-Sectional; Angioplasty, Balloon, Coronary; Atherectomy, Coronary; Cell Division; Cere | 1998 |
Vascular reactivity is impaired in genetic females taking high-dose androgens.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Brachial Artery; Coronary Artery Disease; Endothelium, V | 1998 |
Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine administration on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with normal coronary arteries.
Topics: Aged; Angina Pectoris; Arginine; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; En | 1998 |
Effects of acute L-arginine administration in coronary atherosclerosis.
Topics: Arginine; Coronary Artery Disease; Humans; Nitroglycerin | 1999 |
Serum cholesterol level, cigarette smoking, and vasomotor responses to L-arginine in narrowed epicardial coronary arteries.
Topics: Arginine; Biomarkers; Cholesterol; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; | 2000 |
Impaired vascular responses to nitroglycerin in subjects with coronary atherosclerosis.
Topics: Adult; Aged; Brachial Artery; Coronary Artery Disease; Dose-Response Relationship, Drug; Humans; Lin | 2001 |
N-acetylcysteine improves coronary and peripheral vascular function.
Topics: Acetylcysteine; Adult; Coronary Artery Disease; Coronary Circulation; Dose-Response Relationship, Dr | 2001 |
Vasomotor effects of L- and D-arginine in stenotic atheromatous coronary plaque.
Topics: Analysis of Variance; Arginine; Coronary Artery Disease; Coronary Disease; Endothelium, Vascular; Fe | 2001 |
Role of endothelin-1 in the active constriction of human atherosclerotic coronary arteries.
Topics: Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Endothelin Receptor Antagonists; En | 2001 |
Brachial endothelial function is impaired in patients with systemic lupus erythematosus.
Topics: Adult; Brachial Artery; Coronary Artery Disease; Coronary Vessels; Dilatation; Endothelium, Vascular | 2002 |
Stented bridge: another golden gate for the interventional cardiologist.
Topics: Blood Flow Velocity; Blood Vessel Prosthesis Implantation; Cardiology; Coronary Angiography; Coronar | 2002 |
["The role of spasm in the pathogenesis of stenocardia"].
Topics: Angina Pectoris; Coronary Artery Disease; Coronary Vasospasm; Humans; Nitroglycerin | 1992 |
Short-term administration of estrogen and vascular responses of atherosclerotic coronary arteries.
Topics: Acetylcholine; Animals; Cholesterol; Cholesterol, HDL; Coronary Angiography; Coronary Artery Disease | 1992 |
Effects of intracoronary nitroglycerin on lumen diameter during early follow-up angiography after coronary excimer laser atherectomy.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Angioplasty, Laser; Combined Modality Therapy; Coronary | 1991 |
Responses of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment. Possible role of early coronary atherosclerosis.
Topics: Acetylcholine; Adolescent; Angiography; Coronary Angiography; Coronary Artery Disease; Coronary Vess | 1990 |
Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis.
Topics: Acetylcholine; Adult; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary | 1990 |
Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.
Topics: Acetylcholine; Adolescent; Adult; Biological Products; Bradykinin; Calcimycin; Coronary Artery Disea | 1988 |
Angiographic assessment of human coronary artery endothelial function by measurement of endothelium-dependent vasodilation.
Topics: Acetylcholine; Adult; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Endothelium, | 1989 |
Atherosclerosis and responses of human isolated coronary arteries to endothelium-dependent and -independent vasodilators.
Topics: Animals; Colforsin; Coronary Artery Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Dru | 1989 |
[Clinical and diagnostic features of the initial forms of coronary atherosclerosis].
Topics: Adult; Aged; Angina Pectoris; Coronary Artery Disease; Electrocardiography; Exercise Test; Humans; M | 1989 |
[Differential therapy of myocardial ischemia in females].
Topics: Administration, Sublingual; Adult; Coronary Artery Disease; Coronary Circulation; Coronary Disease; | 1989 |
Konkurrenz zwischen endothelabhängiger und Nitroglygerin-induzierter koronarer Vasodilatation [Competition between endothelium-dependent and nitroglycerin-induced coronary vasodilation].
Topics: Bradykinin; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Endothelium, Vascular; Huma | 1989 |
Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans.
Topics: Adenosine; Adolescent; Adult; Aged; Blood Flow Velocity; Cardiac Catheterization; Coronary Angiograp | 1989 |
Alterations of beta-adrenoceptor mediated relaxations of atherosclerotic human coronary arteries.
Topics: Adult; Colforsin; Coronary Artery Disease; Coronary Vessels; Humans; In Vitro Techniques; Middle Age | 1989 |
Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries.
Topics: Acetylcholine; Angiography; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dose-Re | 1986 |
Cigarette smoking-induced coronary vasoconstriction in atherosclerotic coronary artery disease and prevention by calcium antagonists and nitroglycerin.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Pacing, Artificial; Coronary Artery D | 1987 |
[Clinical course of ischemic heart disease in arteriosclerotic lesions of the anterior interventricular branch of the left coronary artery].
Topics: Adult; Coronary Artery Bypass; Coronary Artery Disease; Humans; Male; Middle Aged; Nitroglycerin | 1987 |
Responses of coronary arteries of cardiac transplant patients to acetylcholine.
Topics: Acetylcholine; Adolescent; Adult; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; F | 1988 |