Page last updated: 2024-11-01

nitroglycerin and Apnea, Obstructive Sleep

nitroglycerin has been researched along with Apnea, Obstructive Sleep in 8 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"Obstructive sleep apnea is associated with increased cardiovascular morbidity and mortality."1.37Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea. ( Butt, M; Dwivedi, G; Khair, OA; Lip, GY; Shantsila, A; Shantsila, E, 2011)
" Dose-response curves to bradykinin and nitroglycerin were obtained from 12 subjects with OSAS and 12 matched control subjects."1.31Vascular reactivity in obstructive sleep apnea syndrome. ( Blaschke, TF; Duchna, HW; Faul, JL; Guilleminault, C; Hoffman, BB; Moreno, H; Stoohs, RA, 2000)
"Worsening nocturnal hypoxemia, measured as nocturnal oxygen saturation nadir or percentage of sleep time spent in hypoxemia (< 90% hemoglobin oxygen saturation), predicted increased interventricular septum thickness (corrected for age and body mass index), prolonged isovolumetric relaxation time, decreased ratio between peak early and late mitral flow velocities, as well as reduced endothelium-dependent dilatory capacity of the brachial artery (all relationships corrected for cofactor age and with p < 0."1.31Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep. ( Caidahl, K; Hedner, J; Kraiczi, H; Peker, Y; Samuelsson, A, 2001)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, A1
Vennelle, M1
Connell, M1
McKillop, G1
Newby, DE1
Douglas, NJ1
Riha, RL1
Nguyen, PK1
Katikireddy, CK1
McConnell, MV1
Kushida, C1
Yang, PC1
Butt, M1
Khair, OA1
Dwivedi, G1
Shantsila, A1
Shantsila, E1
Lip, GY1
Grebe, M1
Eisele, HJ1
Weissmann, N1
Schaefer, C1
Tillmanns, H1
Seeger, W1
Schulz, R1
Duchna, HW3
Stoohs, R1
Guilleminault, C3
Christine Anspach, M1
Schultze-Werninghaus, G2
Orth, M2
Stoohs, RA2
Faul, JL1
Moreno, H1
Hoffman, BB1
Blaschke, TF1
Kraiczi, H1
Caidahl, K1
Samuelsson, A1
Peker, Y1
Hedner, J1
de Zeeuw, J1
Rasche, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Prevalence and Implications of Obstructive Sleep Apnea in the Population of a Wound Center[NCT00679757]300 participants (Actual)Observational2008-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nitroglycerin and Apnea, Obstructive Sleep

ArticleYear
The effect of continuous positive airway pressure therapy on arterial stiffness and endothelial function in obstructive sleep apnea: a randomized controlled trial in patients without cardiovascular disease.
    Sleep medicine, 2013, Volume: 14, Issue:12

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Aorta; Blood Flow Velocity; Cardiovascular Di

2013
Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2010, Sep-03, Volume: 12

    Topics: Adult; Aged; Asymptomatic Diseases; Brachial Artery; California; Cardiovascular Diseases; Continuous

2010

Other Studies

6 other studies available for nitroglycerin and Apnea, Obstructive Sleep

ArticleYear
Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3

    Topics: Acetylcholine; Adult; Blood Pressure; Brachial Artery; Continuous Positive Airway Pressure; Echocard

2011
Antioxidant vitamin C improves endothelial function in obstructive sleep apnea.
    American journal of respiratory and critical care medicine, 2006, Apr-15, Volume: 173, Issue:8

    Topics: Administration, Sublingual; Antioxidants; Ascorbic Acid; Brachial Artery; Endothelium, Vascular; Fem

2006
Vascular endothelial dysfunction in patients with mild obstructive sleep apnea syndrome.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:21-22

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Body Mass Index; Bradykinin; Continuous Positive Airway Pr

2006
Vascular reactivity in obstructive sleep apnea syndrome.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1

    Topics: Blood Pressure; Bradykinin; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nitrog

2000
Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep.
    Chest, 2001, Volume: 119, Issue:4

    Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Cross-Sectional Studies; Diastole; Echocardiograp

2001
[Obstructive sleep apnea syndrome: a cardiovascular risk factor?].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:8

    Topics: Bradykinin; Cardiovascular Diseases; Data Interpretation, Statistical; Endothelium, Vascular; Follow

2001