Compounds > nitroglycerin
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nitroglycerin and Aortic Stenosis

nitroglycerin has been researched along with Aortic Stenosis in 30 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
" Patients with aortic stenosis (moderate or severe) and without aortic stenosis were included if they presented with acute cardiogenic pulmonary edema, received intravenous or sublingual nitroglycerin, and had an echocardiography report available."3.81Complications Associated With Nitrate Use in Patients Presenting With Acute Pulmonary Edema and Concomitant Moderate or Severe Aortic Stenosis. ( Afilalo, J; Claveau, D; Friedland, SN; Piha-Gossack, A; Rudski, L, 2015)
"The beneficial effect of Nitroglycerin (NTG) on myocardial oxygen-supply-demand ratio in severe aortic stenosis has been already demonstrated."3.66Nitrates in aortic valve disease: acute and chronic effects. ( Kreuzer, H; Neuhaus, KL; Neumann, P; Sauer, G; Tebbe, U, 1983)
" A dose-response curve was obtained with nitroglycerin (30, 90, and 150 microg) in 11 patients and sodium nitroprusside (1, 2, and 4 microg/min) in 6."2.69Effect of NO donors on LV diastolic function in patients with severe pressure-overload hypertrophy. ( Hess, OM; Jiang, Z; Kaufmann, PA; Mandinov, L; Matter, CM; Vassalli, G, 1999)
"Nitroglycerin has dependable, short-lived veno- and arterial vasodilatory effects ameliorating ischemia through both preload reduction and coronary vasodilation."1.28Interpretation of cardiac pathophysiology from pressure waveform analysis: effects of nitroglycerin. ( Aguirre, FV; Hilton, TC; Kern, MJ, 1992)
"In patients with aortic regurgitation, cardiac index was significantly lower (P smaller than 0."1.25Clinical, haemodynamic, and coronary angiographic correlates of angina pectoris in patients with severe aortic valve disease. ( Basta, LL; Kioschos, JM; Najjar, S; Raines, D, 1975)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199018 (60.00)18.7374
1990's6 (20.00)18.2507
2000's2 (6.67)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moretti, M1
Fabris, E1
Morosin, M1
Merlo, M1
Barbati, G1
Pinamonti, B1
Gatti, G1
Pappalardo, A1
Sinagra, G1
Bucher, J1
Koyfman, A1
Claveau, D1
Piha-Gossack, A1
Friedland, SN1
Afilalo, J1
Rudski, L1
Newman, DH1
Sharp, AS1
Colombo, A1
BRAUNWALD, E2
OLDHAM, HN1
ROSS, J2
LINHART, JW1
MASON, DT1
FORT, L1
GRECO, H1
COSSIO, P1
COSSIO, PR1
KREUTZER, E1
GLENNY, J1
LAMBREW, CT1
ROCKOFF, SD1
MORROW, AG1
PERLOFF, JG1
RONAN, JA1
DELEON, AC1
Leinonen, P1
Bermudez, GA1
Abdelnur, R1
Midell, A1
DeMeester, T1
Laskey, WK1
St John Sutton, M1
Untereker, WJ1
Martin, JL1
Hirshfeld, JW1
Reichek, N1
Tebbe, U2
Neuhaus, KL2
Sauer, G2
Neumann, P1
Kreuzer, H1
Jebavý, P1
Bale, R1
Powles, A1
Wyatt, R1
Lip, GY1
Singh, SP1
Caracciolo, EA1
Underwood, D1
Kern, MJ4
Matter, CM1
Mandinov, L1
Kaufmann, PA1
Vassalli, G1
Jiang, Z1
Hess, OM1
Grose, R1
Nivatpumin, T1
Katz, S1
Yipintsoi, T1
Scheuer, J1
Huang, MT1
Goodman, MA1
Delaney, TB1
Basta, LL1
Raines, D1
Najjar, S1
Kioschos, JM1
Aguirre, FV1
Hilton, TC1
Laurent, M1
Leborgne, O1
Clement, C1
Foulgoc, JL1
Le Helloco, A1
Almange, C1
Leborgne, P1
Deligonul, U1
Stoddard, MF1
Pearson, AC1
Ratcliff, J1
Mrosek, DG1
Labovitz, AJ1
Lew, WY1
Ferrero, C1
Burakovskiĭ, VI1
Bukharin, VA1

Trials

1 trial available for nitroglycerin and Aortic Stenosis

ArticleYear
Effect of NO donors on LV diastolic function in patients with severe pressure-overload hypertrophy.
    Circulation, 1999, May-11, Volume: 99, Issue:18

    Topics: Adult; Aged; Aortic Valve Stenosis; Cardiac Catheterization; Coronary Angiography; Coronary Circulat

1999

Other Studies

29 other studies available for nitroglycerin and Aortic Stenosis

ArticleYear
Prognostic significance of atrial fibrillation and severity of symptoms of heart failure in patients with low gradient aortic stenosis and preserved left ventricular ejection fraction.
    The American journal of cardiology, 2014, Dec-01, Volume: 114, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti

2014
Does Initiation of Therapeutic Hypothermia in the Out-of-Hospital Environment Improve Neurologic Outcomes?
    Annals of emergency medicine, 2015, Volume: 66, Issue:4

    Topics: Aortic Valve Stenosis; Female; Humans; Male; Nitroglycerin; Pulmonary Edema; Vasodilator Agents

2015
Complications Associated With Nitrate Use in Patients Presenting With Acute Pulmonary Edema and Concomitant Moderate or Severe Aortic Stenosis.
    Annals of emergency medicine, 2015, Volume: 66, Issue:4

    Topics: Aged, 80 and over; Aortic Valve Stenosis; Canada; Female; Humans; Hypotension; Male; Nitroglycerin;

2015
Negative Studies Are Usually Right: Vetting the Pseudoaxioms.
    Annals of emergency medicine, 2015, Volume: 66, Issue:4

    Topics: Aortic Valve Stenosis; Female; Humans; Male; Nitroglycerin; Pulmonary Edema; Vasodilator Agents

2015
An innocent bystander in the coronary tree.
    European heart journal, 2009, Volume: 30, Issue:15

    Topics: Aortic Valve Stenosis; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential

2009
THE CIRCULATORY RESPONSE OF PATIENTS WITH IDIOPATHIC HYPERTROPHIC SUBAORTIC STENOSIS TO NITROGLYCERIN AND TO THE VALSALVA MANEUVER.
    Circulation, 1964, Volume: 29

    Topics: Aortic Valve Stenosis; Blood Pressure; Brachial Artery; Cardiac Catheterization; Cardiomyopathy, Hyp

1964
[CARDIAC AUSCULTATION. V. DIAGNOSIS OF THE SIGNIFICANCE OF THE CARDIAC MURMURS USING THE AMYLNITRITE OR NITROGLYCERINE TEST].
    Prensa medica argentina, 1963, Sep-06, Volume: 50

    Topics: Amyl Nitrite; Aortic Valve Stenosis; Child; Diagnosis, Differential; Heart Auscultation; Heart Defec

1963
IDIOPATHIC HYPERTROPHIC SUBAORTIC STENOSIS. I. A DESCRIPTION OF THE DISEASE BASED UPON AN ANALYSIS OF 64 PATIENTS.
    Circulation, 1964, Volume: 30

    Topics: Adolescent; Amyl Nitrite; Angiocardiography; Aortic Valve Stenosis; Blood Pressure; Cardiac Catheter

1964
THE EFFECT OF NITROGLYCERIN ON LEFT VENTRICULAR WALL TENSION IN FIXED ORIFICE AORTIC STENOSIS.
    Circulation, 1965, Volume: 32

    Topics: Adolescent; Aortic Valve Stenosis; Blood Pressure; Cardiac Catheterization; Heart Function Tests; He

1965
[About listening the patient].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:15

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Coronary Artery Disease; Female; Humans; Nitroglycer

2003
Coronary artery disease in aortic stenosis: importance of coronary arteriography and surgical implications.
    Angiology, 1983, Volume: 34, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Aortic Valve Stenosis; Coronary Disease; Female; Heart Valve Prosthesi

1983
Mechanics of pulsus alternans in aortic valve stenosis.
    The American journal of cardiology, 1983, Oct-01, Volume: 52, Issue:7

    Topics: Aortic Valve Stenosis; Echocardiography; Heart Ventricles; Humans; Myocardial Contraction; Nitroglyc

1983
Nitrates in aortic valve disease: acute and chronic effects.
    Zeitschrift fur Kardiologie, 1983, Volume: 72 Suppl 3

    Topics: Aortic Valve Insufficiency; Aortic Valve Stenosis; Hemodynamics; Humans; Isosorbide Dinitrate; Nitro

1983
[Changes of haemodynamics after administration of nitroglycerin in patients with aortal stenosis (author's transl)].
    Casopis lekaru ceskych, 1980, Volume: 119, Issue:43-44

    Topics: Adult; Aortic Valve Stenosis; Female; Hemodynamics; Humans; Male; Middle Aged; Nitroglycerin

1980
[Effect of nitroglycerin on left ventricular hemodynamics, wall stress and myocardial oxygen supply/demand ratio in aortic stenosis (author's transl)].
    Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:9

    Topics: Aortic Valve Stenosis; Blood Pressure; Coronary Circulation; Female; Heart Ventricles; Hemodynamics;

1981
I.V. glyceryl trinitrate: haemodynamic effects and clinical use in cardiac surgery.
    British journal of anaesthesia, 1982, Volume: 54, Issue:3

    Topics: Aortic Valve Stenosis; Coronary Artery Bypass; Hemodynamics; Humans; Infusions, Parenteral; Nitrogly

1982
Nitrates and severe aortic stenosis.
    British heart journal, 1995, Volume: 73, Issue:6

    Topics: Acute Disease; Aged; Aortic Valve Stenosis; Heart Failure; Humans; Male; Nitroglycerin

1995
Attenuation of hypertensive-induced pulsus alternans by nifedipine and nitroglycerin.
    Catheterization and cardiovascular diagnosis, 1994, Volume: 31, Issue:2

    Topics: Administration, Sublingual; Aged; Aortic Valve Stenosis; Atrial Fibrillation; Blood Pressure; Cardia

1994
Mechanism of nitroglycerin effect in valvular aortic stenosis.
    The American journal of cardiology, 1979, Volume: 44, Issue:7

    Topics: Aged; Aortic Valve Stenosis; Female; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Myoc

1979
Pre-infarction angina secondary to calcific aortic stenosis with Bernheim's effect.
    Clinical cardiology, 1978, Volume: 1, Issue:2

    Topics: Angina Pectoris; Aortic Valve Stenosis; Blood Pressure; Calcinosis; Hemodynamics; Humans; Intra-Aort

1978
Clinical, haemodynamic, and coronary angiographic correlates of angina pectoris in patients with severe aortic valve disease.
    British heart journal, 1975, Volume: 37, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Blood Pressure; Car

1975
Interpretation of cardiac pathophysiology from pressure waveform analysis: effects of nitroglycerin.
    Catheterization and cardiovascular diagnosis, 1992, Volume: 25, Issue:3

    Topics: Aged; Angina, Unstable; Aortic Valve Stenosis; Blood Pressure; Coronary Circulation; Coronary Diseas

1992
Systolic intra-cavitary gradients following aortic valve replacement: an echo-Doppler study.
    European heart journal, 1991, Volume: 12, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Blood Flow Velocity; Echocardio

1991
Interpretation of cardiac pathophysiology from pressure waveform analysis: III. Intraventricular pressure gradients.
    Catheterization and cardiovascular diagnosis, 1991, Volume: 22, Issue:2

    Topics: Adult; Aged; Aortic Valve Stenosis; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Female; H

1991
Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler echocardiography in humans.
    Circulation, 1989, Volume: 79, Issue:6

    Topics: Aortic Valve Stenosis; Coronary Disease; Echocardiography; Echocardiography, Doppler; Female; Humans

1989
Evaluation of left ventricular diastolic function.
    Circulation, 1989, Volume: 79, Issue:6

    Topics: Aortic Valve Stenosis; Coronary Disease; Echocardiography, Doppler; Heart; Humans; Myocardial Contra

1989
[Apropos of the detection of obstructive cardiomyopathies].
    Atti della Societa italiana di cardiologia, 1968, Volume: 2

    Topics: Amyl Nitrite; Aortic Valve Insufficiency; Aortic Valve Stenosis; Carotid Arteries; Heart Auscultatio

1968
[Basic surgical problems in congenital heart defects].
    Kardiologiia, 1969, Volume: 9, Issue:10

    Topics: Age Factors; Aortic Coarctation; Aortic Valve Stenosis; Child; Child, Preschool; Heart Defects, Cong

1969
Problems with prosthetic valve surgery.
    Postgraduate medicine, 1971, Volume: 49, Issue:6

    Topics: Adult; Anemia, Hemolytic; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Cardia

1971