nitroglycerin has been researched along with Aortic Coarctation in 9 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vasorelaxation by histamine, iloprost and nitroglycerin are impaired in hypertension." | 3.68 | Vascular smooth muscle responses to endothelial autacoids in rats with chronic coarctation hypertension. ( Bell, DR, 1993) |
| "We assessed the degree of reactive hyperemia (RH) produced after distal cuff occlusion and release and the changes in arterial diameter in response to RH (with increased flow causing endothelium-dependent dilation) and to glyceryltrinitrate (GTN, an endothelium-independent dilator)." | 1.29 | Arterial reactivity is significantly impaired in normotensive young adults after successful repair of aortic coarctation in childhood. ( Celermajer, DS; Deanfield, JE; Gardiner, HM; Georgakopoulos, D; Robinson, J; Sorensen, KE; Thomas, O, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moerman, A | 1 |
| Bové, T | 1 |
| François, K | 1 |
| Jacobs, S | 1 |
| Deblaere, I | 1 |
| Wouters, P | 1 |
| De Hert, S | 1 |
| Ogawa, Y | 1 |
| Okumura, K | 1 |
| Matsui, H | 1 |
| Fukami, Y | 1 |
| Saburi, Y | 1 |
| Iami, H | 1 |
| Mizuno, T | 1 |
| Nishimoto, Y | 1 |
| FRICK, MH | 1 |
| HALONEN, PI | 1 |
| Heger, M | 1 |
| Willfort, A | 1 |
| Neunteufl, T | 1 |
| Rosenhek, R | 1 |
| Gabriel, H | 1 |
| Wollenek, G | 1 |
| Wimmer, M | 1 |
| Maurer, G | 1 |
| Baumgartner, H | 1 |
| Estafanous, FG | 1 |
| Tarazi, RC | 1 |
| Bell, DR | 1 |
| Gardiner, HM | 1 |
| Celermajer, DS | 1 |
| Sorensen, KE | 1 |
| Georgakopoulos, D | 1 |
| Robinson, J | 1 |
| Thomas, O | 1 |
| Deanfield, JE | 2 |
| de Divitiis, M | 1 |
| Pilla, C | 1 |
| Kattenhorn, M | 1 |
| Zadinello, M | 1 |
| Donald, A | 1 |
| Leeson, P | 1 |
| Wallace, S | 1 |
| Redington, A | 1 |
| Burakovskiĭ, VI | 1 |
| Bukharin, VA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| LOVE-COARCT Study: Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment[NCT03262753] | 90 participants (Anticipated) | Observational | 2013-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitroglycerin and Aortic Coarctation
| Article | Year |
|---|---|
Society of cardiovascular anesthesiologists: the effect of blood pressure regulation during aortic coarctation repair on brain, kidney, and muscle oxygen saturation measured by near-infrared spectroscopy: a randomized, clinical trial.
Topics: Aging; Anesthesia, Intravenous; Aortic Coarctation; Blood Pressure; Brain Chemistry; Cardiac Surgica | 2013 |
Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery.
Topics: Adult; Age Factors; Aortic Coarctation; Blood Flow Velocity; Brachial Artery; Cardiovascular Surgica | 2001 |
7 other studies available for nitroglycerin and Aortic Coarctation
| Article | Year |
|---|---|
Relaxant properties mediated by nitroglycerin in aortic coarctation hypertensive rats.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Blood Pressure; Charybdotoxin; Disea | 2002 |
The flicker fusion threshold and its response to nitroglycerin in hypertension and in coarctation of the aorta.
Topics: Aorta; Aortic Coarctation; Flicker Fusion; Humans; Hypertension; Nitrites; Nitroglycerin | 1961 |
Vascular dysfunction after coarctation repair is related to the age at surgery.
Topics: Adolescent; Adult; Age Factors; Aortic Coarctation; Blood Vessel Prosthesis Implantation; Brachial A | 2005 |
Systemic arterial hypertension associated with cardiac surgery.
Topics: Angiotensin II; Antihypertensive Agents; Aortic Coarctation; Aortic Valve; Cardiac Surgical Procedur | 1980 |
Vascular smooth muscle responses to endothelial autacoids in rats with chronic coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Autacoids; Chronic Di | 1993 |
Arterial reactivity is significantly impaired in normotensive young adults after successful repair of aortic coarctation in childhood.
Topics: Adult; Aortic Coarctation; Blood Flow Velocity; Brachial Artery; Child, Preschool; Exercise; Female; | 1994 |
[Basic surgical problems in congenital heart defects].
Topics: Age Factors; Aortic Coarctation; Aortic Valve Stenosis; Child; Child, Preschool; Heart Defects, Cong | 1969 |