nitroglycerin has been researched along with Angiospasm, Intracranial in 7 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the rabbit subarachnoid hemorrhage (SAH) model, the sensitivity of spastic basilar arteries to nitric oxide (NO) was enhanced whereas the endothelial function to release/produce NO became impaired, as described previously." | 5.31 | Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin. ( Azuma, H; Hirakawa, K; Isotani, E; Ito, Y; Mizuno, Y, 2000) |
| "Patients with cerebral vasospasm caused by aneurysmal subarachnoid hemorrhage (aSAH) are often treated with intra-arterial (IA) vasodilator infusion." | 1.62 | Use of single versus multiple vasodilator agents in the treatment of cerebral vasospasm: is more better than less? ( Bulsara, K; Chen, PR; Day, AL; Erkmen, K; Kim, DH; Lopez-Rivera, V; Oni-Orisan, AO; Sanzgiri, A; Sheriff, FG; Sheth, S; Vahidy, FS, 2021) |
| "Delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is a major cause of high morbidity and mortality." | 1.37 | Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo. ( Fandino, J; Fathi, AR; Graupner, T; Jakob, SM; Marbacher, S; Schroth, G; Wehrli, F, 2011) |
| "In the rabbit subarachnoid hemorrhage (SAH) model, the sensitivity of spastic basilar arteries to nitric oxide (NO) was enhanced whereas the endothelial function to release/produce NO became impaired, as described previously." | 1.31 | Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin. ( Azuma, H; Hirakawa, K; Isotani, E; Ito, Y; Mizuno, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, PR | 1 |
| Bulsara, K | 1 |
| Lopez-Rivera, V | 1 |
| Sheriff, FG | 1 |
| Sanzgiri, A | 1 |
| Sheth, S | 1 |
| Oni-Orisan, AO | 1 |
| Vahidy, FS | 1 |
| Erkmen, K | 1 |
| Kim, DH | 1 |
| Day, AL | 1 |
| Fathi, AR | 1 |
| Marbacher, S | 2 |
| Graupner, T | 2 |
| Wehrli, F | 1 |
| Jakob, SM | 2 |
| Schroth, G | 1 |
| Fandino, J | 2 |
| Neuschmelting, V | 1 |
| Pluta, RM | 1 |
| Ito, Y | 1 |
| Isotani, E | 1 |
| Mizuno, Y | 1 |
| Azuma, H | 1 |
| Hirakawa, K | 1 |
| Tanaka, Y | 2 |
| Masuzawa, T | 2 |
| Saito, M | 2 |
| Yamada, T | 2 |
| Ebihara, A | 1 |
| Iwasa, H | 1 |
| Mori, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453] | 150 participants (Actual) | Observational | 2021-08-18 | Active, not recruiting | |||
| Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage[NCT05686265] | 32 participants (Anticipated) | Observational | 2023-05-11 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Angiospasm, Intracranial
| Article | Year |
|---|---|
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
6 other studies available for nitroglycerin and Angiospasm, Intracranial
| Article | Year |
|---|---|
Use of single versus multiple vasodilator agents in the treatment of cerebral vasospasm: is more better than less?
Topics: Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nicardipine; Nitroglycerin; Retrospect | 2021 |
Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo.
Topics: Animals; Disease Models, Animal; Injections, Spinal; Intracranial Aneurysm; Male; Nitroglycerin; Rab | 2011 |
Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo.
Topics: Animals; Basilar Artery; Cerebral Angiography; Female; Injections, Spinal; Male; Nimodipine; Nitric | 2008 |
Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin.
Topics: Administration, Cutaneous; Animals; Basilar Artery; Coronary Angiography; Hemodynamics; In Vitro Tec | 2000 |
Inhibitory effects of verapamil and nitroglycerin on contraction and cytosolic Ca2+ levels in cerebrovascular smooth muscle during chronic cerebral vasospasm.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Cytosol; Disease Models, Anima | 2001 |
Combined administration of Fasudil hydrochloride and nitroglycerin for treatment of cerebral vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Brain Ischemia; Drug Combinations; Female; Huma | 2001 |