nitroglycerin has been researched along with Aneurysm, Anterior Cerebral Artery in 26 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cardiovascular effects of nitroglycerine (TNG) were studied in 30 patients requiring controlled hypotension for intracranial aneurysm surgery." | 3.67 | Use of nitroglycerine to produce controlled decreases in mean arterial pressure to less than 50 mm Hg. ( Dagreou, F; Gallais, S; Guggiari, M; Lienhart, A; Mottet, P; Philippon, J; Viars, P, 1985) |
| "Deliberate hypotension was induced by using nitroglycerin (NG) during anesthesia in 13 patients with intracranial aneurysm, who underwent clipping surgery." | 3.67 | [Clinical study on hypotensive anesthesia with nitroglycerin]. ( Kadoya, T; Kurokawa, M; Ogata, M; Takara, H; Tanaka, T, 1985) |
| "In the case of hypertensive encephalopathy, the lowering of blood pressure is therapeutic as well as diagnostic." | 2.43 | [Antihypertensive management in acute cerebral stroke]. ( Ziliene, V, 2005) |
| "Delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) is a major cause of high morbidity and mortality." | 1.37 | Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo. ( Fandino, J; Fathi, AR; Graupner, T; Jakob, SM; Marbacher, S; Schroth, G; Wehrli, F, 2011) |
| "The effects of intravenous nitroglycerin (NTG) combined with dopamine on intracranial pressure (ICP) and cerebral arteriovenous oxygen difference (AVDO2) were studied in 11 patients with acute subarachnoid haemorrhage (SAH)." | 1.29 | Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage. ( Aoki, H; Boku, E; Goda, K; Imanishi, M; Iwanaga, H; Koshimae, N; Okuchi, K; Sakaki, T; Tokunaga, H, 1995) |
| "Especially in patients with severe subarachnoid hemorrhage classified as CT group 3 or 4, symptomatic vasospasm occurred in 11 patients (30." | 1.28 | [Clinical effect of nitroglycerin (GTN) on prevention of cerebral vasospasm]. ( Goto, T; Ogayama, H; Sasaki, J; Sasanuma, J; Watanabe, K, 1991) |
| "29 patients were operated on cerebral aneurysms and arterio-venous malformations in hypotension induced by sodium nitroprusside, nitroglycerin or a combination of the two substances." | 1.26 | [Postoperative reactions of blood pressure after neurosurgical operations in deliberate hypotension (author's transl)]. ( Kirchner, E; Spring, A; Spring, G, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mikulandra, S | 1 |
| Hirs, I | 1 |
| Deutsch, J | 1 |
| Fathi, AR | 1 |
| Marbacher, S | 1 |
| Graupner, T | 1 |
| Wehrli, F | 1 |
| Jakob, SM | 1 |
| Schroth, G | 1 |
| Fandino, J | 1 |
| Ogawa-Okamoto, C | 1 |
| Saito, S | 1 |
| Nishihara, F | 1 |
| Yuki, N | 1 |
| Goto, F | 1 |
| Ziliene, V | 1 |
| Pluta, RM | 1 |
| Di Giugno, G | 2 |
| Rosa, G | 2 |
| Orfei, P | 2 |
| Bellerino, O | 1 |
| Lamur, M | 1 |
| Blanchet, P | 1 |
| Boularan, A | 1 |
| Buxeda, M | 1 |
| Dabbach, E | 1 |
| Roquefeuil, B | 1 |
| Artru, F | 1 |
| Philippon, B | 1 |
| Poussel, JF | 1 |
| Montarry, M | 1 |
| Deleuze, R | 1 |
| Murakawa, T | 2 |
| Yamashita, M | 2 |
| Satone, T | 1 |
| Kudo, M | 2 |
| Matsuki, A | 2 |
| Oyama, T | 2 |
| Spring, A | 1 |
| Spring, G | 1 |
| Kirchner, E | 1 |
| Farelli, S | 2 |
| Mazzone, P | 2 |
| Robbiano, F | 1 |
| Lagerkranser, M | 1 |
| Iwanaga, H | 2 |
| Okuchi, K | 1 |
| Koshimae, N | 1 |
| Goda, K | 1 |
| Imanishi, M | 1 |
| Tokunaga, H | 1 |
| Aoki, H | 1 |
| Boku, E | 1 |
| Sakaki, T | 1 |
| Sahin, A | 1 |
| Erçelen, O | 1 |
| Aypar, U | 1 |
| Erbengi, A | 1 |
| Cuadrado Mounir, LF | 1 |
| Abou-Madi Bruno, MN | 1 |
| Domb, B | 1 |
| Barnes, J | 1 |
| Trop, D | 1 |
| Abe, K | 1 |
| Yoshiya, I | 1 |
| Sasanuma, J | 1 |
| Goto, T | 1 |
| Ogayama, H | 1 |
| Sasaki, J | 1 |
| Watanabe, K | 1 |
| Tanaka, S | 1 |
| Maeyama, R | 1 |
| Kawahara, K | 1 |
| Arimura, H | 1 |
| Fukuda, A | 1 |
| Toyota, Y | 1 |
| Maktabi, M | 1 |
| Warner, D | 1 |
| Sokoll, M | 1 |
| Boarini, D | 1 |
| Adolphson, A | 1 |
| Speed, T | 1 |
| Kassell, N | 1 |
| Fasano, VA | 1 |
| Urciuoli, R | 1 |
| Bolognese, P | 1 |
| Mostert, M | 1 |
| Guggiari, M | 1 |
| Dagreou, F | 1 |
| Lienhart, A | 1 |
| Gallais, S | 1 |
| Mottet, P | 1 |
| Philippon, J | 1 |
| Viars, P | 1 |
| Wakayama, S | 1 |
| Ryba, M | 1 |
| Johansson, K | 1 |
| Cybulska, A | 1 |
| Kurokawa, M | 1 |
| Ogata, M | 1 |
| Takara, H | 1 |
| Kadoya, T | 1 |
| Tanaka, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453] | 150 participants (Actual) | Observational | 2021-08-18 | Active, not recruiting | |||
| Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage[NCT05686265] | 32 participants (Anticipated) | Observational | 2023-05-11 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitroglycerin and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
[Antihypertensive management in acute cerebral stroke].
Topics: Acute Disease; Adult; Antihypertensive Agents; Brain Injuries; Cerebrovascular Circulation; Emergenc | 2005 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.
Topics: Humans; Intracranial Aneurysm; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxid | 2008 |
3 trials available for nitroglycerin and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
[Preliminary report in the use of nitroglycerin as a hypotensive agent in neurosurgery].
Topics: Adolescent; Adult; Antihypertensive Agents; Clinical Trials as Topic; Drug Evaluation; Female; Heart | 1979 |
Carbon dioxide reactivity and local cerebral blood flow during prostaglandin E1- or nitroglycerin-induced hypotension.
Topics: Adult; Aged; Alprostadil; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Cerebrovascular Ci | 1992 |
[Controlled hypotension with sodium nitroprusside or trinitroglycerin in intracranial vascular surgery].
Topics: Adolescent; Adult; Blood Pressure; Female; Ferricyanides; Humans; Hypotension, Controlled; Intracran | 1987 |
21 other studies available for nitroglycerin and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
Unusual use of nitroglycerin for severe bronchospasm during coiling embolization of ruptured intracranial aneurysm.
Topics: Adult; Algorithms; Aneurysm, Ruptured; Bronchial Spasm; Embolization, Therapeutic; Humans; Intracran | 2008 |
Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo.
Topics: Animals; Disease Models, Animal; Injections, Spinal; Intracranial Aneurysm; Male; Nitroglycerin; Rab | 2011 |
Blood pressure control with glyceryl trinitrate during electroconvulsive therapy in a patient with cerebral aneurysm.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Electroconvulsive Therapy; Female; Humans; Hypertensi | 2003 |
[Controlled hypotension in the surgery of intracranial arterial aneurysms. Comparison of sodium nitroprusside, trimethaphan and trinitroglycerin].
Topics: Adult; Aged; Anesthesia, General; Ferricyanides; Humans; Hypotension, Controlled; Intracranial Aneur | 1983 |
[Controlled hypotension in the surgery of intracranial arterial aneurysms].
Topics: Adult; Aged; Humans; Hypotension, Controlled; Intracranial Aneurysm; Middle Aged; Neuroleptanalgesia | 1984 |
[Effects of intravenous nitroglycerin on blood pressure, intracranial pressure and total and regional cerebral blood flow in cases of subarachnoid hemorrhage with vasospasm].
Topics: Blood Pressure; Cerebrovascular Circulation; Humans; Intracranial Aneurysm; Intracranial Pressure; I | 1984 |
[Effect of nitroglycerin-induced hypotension on pituitary-adrenocortical function].
Topics: Female; Halothane; Humans; Hypothermia, Induced; Infusions, Parenteral; Intracranial Aneurysm; Male; | 1984 |
[Postoperative reactions of blood pressure after neurosurgical operations in deliberate hypotension (author's transl)].
Topics: Adolescent; Adult; Aged; Blood Pressure; Drug Interactions; Female; Ferricyanides; Heart Rate; Human | 1980 |
[Controlled hypotension in the neurosurgical treatment of intracranial aneurysm. Comparison of trimethaphan and nitroglycerin].
Topics: Adult; Aged; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; Male; Middle Aged; Nitr | 1982 |
Cardiovascular effects of nitroglycerin as a hypotensive agent in cerebral aneurysm surgery.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hypotension, Controlled; Intrac | 1982 |
Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage.
Topics: Adult; Aged; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; H | 1995 |
Cerebral aneurysm surgery in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; | 1998 |
[Clinical effect of nitroglycerin (GTN) on prevention of cerebral vasospasm].
Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Intracranial Aneurysm; Ischemic Att | 1991 |
[Ruptured aneurysm during pregnancy. Case report].
Topics: Adult; Female; Fetal Monitoring; Heart Rate, Fetal; Humans; Hypotension, Controlled; Intracranial An | 1987 |
Comparison of nitroprusside, nitroglycerin, and deep isoflurane anesthesia for induced hypotension.
Topics: Blood Pressure; Ferricyanides; Hemodynamics; Humans; Hypotension, Controlled; Intracranial Aneurysm; | 1986 |
[Controlled hypotension by using nitroglycerin and neurologic results. Computer analysis of 50 cases operated on for intracranial aneurysm].
Topics: Adult; Blood Pressure; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; Male; Middle | 1987 |
Intraoperative use of laser Doppler in the study of cerebral microvascular circulation.
Topics: Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; M | 1988 |
Use of nitroglycerine to produce controlled decreases in mean arterial pressure to less than 50 mm Hg.
Topics: Adult; Anesthesia, General; Blood Pressure; Female; Hemodynamics; Humans; Hypotension, Controlled; I | 1985 |
[Effect of nitroglycerin-induced hypotension on plasma human growth hormone and insulin levels].
Topics: Blood Glucose; Female; Growth Hormone; Humans; Hypotension, Controlled; Insulin; Intracranial Aneury | 1985 |
Brain metabolism in deep controlled hypotension in neurosurgical patients.
Topics: Adult; Brain; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; L-Lactate Dehydrogenas | 1985 |
[Clinical study on hypotensive anesthesia with nitroglycerin].
Topics: Adult; Anesthesia, Intravenous; Female; Heart Rate; Humans; Hypotension, Controlled; Intracranial An | 1985 |