Page last updated: 2024-11-01

nitroglycerin and Albuminuria

nitroglycerin has been researched along with Albuminuria in 14 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"We compared flow-mediated dilatation (FMD) and nitroglycerine-dependent dilatation (NDD) in African-American diabetic subjects with persistent microalbuminuria (n = 35) despite ACEI therapy and those in whom microalbuminuria had resolved (n = 15)."5.12Impaired vascular reactivity in African-American patients with type 2 diabetes mellitus and microalbuminuria or proteinuria despite angiotensin-converting enzyme inhibitor therapy. ( Asnani, S; Fonseca, V; Jawa, A; Nachimuthu, S; Pendergrass, M, 2006)
"In a double-blind, randomized crossover study, 16 Type 1 diabetes mellitus patients with microalbuminuria received 6 weeks of atorvastatin 40 mg/day or placebo, separated by a 4-week washout."5.11Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuria. ( Chan, DC; Dogra, GK; Stanton, K; Watts, GF, 2005)
" We examined the effects of an intravenous infusion of L-arginine and a sublingual administration of nitroglycerin on the brachial, retinal, and interlobar arterial hemodynamics in 20 type 2 diabetic patients (10 with normoalbuminuria and 10 with microalbuminuria) and 10 aged-matched control subjects."5.09Impaired endothelium-dependent vascular responses of retinal and intrarenal arteries in patients with type 2 diabetes. ( Emoto, M; Inaba, M; Ishimura, E; Kanda, H; Kawagishi, T; Matsuyoshi, M; Morii, H; Nishizawa, Y; Okuno, Y; Taniwaki, H, 1999)
" In the present study we evaluated resistive index at baseline and after vasodilation induced by nitroglycerine in normoalbuminuric patients with type 2 diabetes or essential hypertension, relating the values to indices of systemic vascular dysfunction."3.77Dynamic evaluation of renal resistive index in normoalbuminuric patients with newly diagnosed hypertension or type 2 diabetes. ( Bruno, RM; Daghini, E; Di Paco, I; Ghiadoni, L; Landini, L; Magagna, A; Salvati, A; Santini, E; Solini, A; Taddei, S; Versari, D, 2011)
"In adults with type 2 diabetes and known or suspected atherosclerosis, arterial smooth muscle-dependent dilatation was shown to be significantly impaired in cigarette smokers and those with elevated urinary albumin levels."2.79Cigarette smoking and albuminuria are associated with impaired arterial smooth muscle function in patients with type 2 diabetes mellitus: a FIELD substudy. ( Celermajer, DS; Harmer, JA; Keech, AC; Marwick, TH; Meredith, IT; Skilton, MR; Veillard, AS; Watts, GF, 2014)
" Basal and stimulated endothelial nitric oxide (NO) bioavailability was assessed by measurement of the responses to intra-arterial N(G)-monomethyl-l-arginine (l-NMMA) and bradykinin, respectively."2.71Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. ( Clapp, BR; Hingorani, AD; Kharbanda, RK; MacAllister, RJ; Mohamed-Ali, V; Stephens, JW; Vallance, P, 2004)
"Twenty-three patients with Type 2 diabetes, normal UAE and no vascular complications were examined."1.31Impaired vascular reactivity is present despite normal levels of von Willebrand factor in patients with uncomplicated Type 2 diabetes. ( Eskildsen, PC; Ihlemann, N; Stokholm, KH, 2002)
"Abnormal EDD was found in 12 IDDM adolescents (diabetes duration 3."1.30Macroangiopathy--does it play a role in young people? ( Celermajer, DS; Donaghue, KC; Fung, A; McCredie, R; Robinson, J; Silink, M, 1998)
"FMD in IDDM patients was decreased (12."1.29Endothelium-dependent and -independent vasodilation of large arteries in normoalbuminuric insulin-dependent diabetes mellitus. ( Aarsen, M; Donker, AJ; Lambert, J; Stehouwer, CD, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's7 (50.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harmer, JA1
Keech, AC1
Veillard, AS1
Skilton, MR1
Marwick, TH1
Watts, GF4
Meredith, IT1
Celermajer, DS2
Bruno, RM1
Daghini, E1
Landini, L1
Versari, D1
Salvati, A1
Santini, E1
Di Paco, I1
Magagna, A1
Taddei, S1
Ghiadoni, L1
Solini, A1
Chan, NN1
Fuller, JH1
Rubens, M1
Colhoun, HM1
Clapp, BR1
Hingorani, AD1
Kharbanda, RK1
Mohamed-Ali, V1
Stephens, JW1
Vallance, P1
MacAllister, RJ1
Dogra, GK1
Chan, DC1
Stanton, K2
Jawa, A1
Nachimuthu, S1
Pendergrass, M1
Asnani, S1
Fonseca, V1
Malik, AR1
Sultan, S1
Turner, ST1
Kullo, IJ1
Zenere, BM1
Arcaro, G1
Saggiani, F1
Rossi, L1
Muggeo, M1
Lechi, A1
Lambert, J1
Aarsen, M1
Donker, AJ1
Stehouwer, CD1
Donaghue, KC1
Robinson, J1
McCredie, R1
Fung, A1
Silink, M1
Kawagishi, T1
Matsuyoshi, M1
Emoto, M1
Taniwaki, H1
Kanda, H1
Okuno, Y1
Inaba, M1
Ishimura, E1
Nishizawa, Y1
Morii, H1
Meeking, DR1
Cummings, MH1
Thorne, S1
Donald, A1
Clarkson, P1
Crook, JR1
Shaw, KM1
Dogra, G1
Rich, L1
Ihlemann, N1
Stokholm, KH1
Eskildsen, PC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open Clinical Trial of the Use of Antioxidants and Pentoxifylline as Adjuvant Therapy to Standard Therapy in Patients With and Without Septic Shock Secondary to COVID-19 Severe Pneumonia[NCT04570254]110 participants (Actual)Interventional2020-08-19Completed
A Double-blind, Randomised, Placebo-controlled Parallel Study to Investigate the Effect of Dietary Nitrate on a Model of Vascular Dysfunction in Healthy Volunteers[NCT02715635]Phase 178 participants (Actual)Interventional2016-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for nitroglycerin and Albuminuria

ArticleYear
Cigarette smoking and albuminuria are associated with impaired arterial smooth muscle function in patients with type 2 diabetes mellitus: a FIELD substudy.
    Diabetes research and clinical practice, 2014, Volume: 106, Issue:2

    Topics: Aged; Albuminuria; Brachial Artery; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, V

2014
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
    Cardiovascular research, 2004, Oct-01, Volume: 64, Issue:1

    Topics: Adult; Albuminuria; Analysis of Variance; Arginine; Ascorbic Acid; Biological Availability; Bradykin

2004
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
    Cardiovascular research, 2004, Oct-01, Volume: 64, Issue:1

    Topics: Adult; Albuminuria; Analysis of Variance; Arginine; Ascorbic Acid; Biological Availability; Bradykin

2004
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
    Cardiovascular research, 2004, Oct-01, Volume: 64, Issue:1

    Topics: Adult; Albuminuria; Analysis of Variance; Arginine; Ascorbic Acid; Biological Availability; Bradykin

2004
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
    Cardiovascular research, 2004, Oct-01, Volume: 64, Issue:1

    Topics: Adult; Albuminuria; Analysis of Variance; Arginine; Ascorbic Acid; Biological Availability; Bradykin

2004
Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuria.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Albuminuria; Apolipoproteins B; Atorvastatin; Brachial Artery; Cholesterol,

2005
Impaired vascular reactivity in African-American patients with type 2 diabetes mellitus and microalbuminuria or proteinuria despite angiotensin-converting enzyme inhibitor therapy.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:1

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inh

2006
Impaired endothelium-dependent vascular responses of retinal and intrarenal arteries in patients with type 2 diabetes.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:10

    Topics: Adult; Albuminuria; Arginine; Blood Glucose; Blood Pressure; Brachial Artery; Diabetes Mellitus, Typ

1999

Other Studies

9 other studies available for nitroglycerin and Albuminuria

ArticleYear
Dynamic evaluation of renal resistive index in normoalbuminuric patients with newly diagnosed hypertension or type 2 diabetes.
    Diabetologia, 2011, Volume: 54, Issue:9

    Topics: Adult; Albuminuria; Blood Glucose; Case-Control Studies; Comorbidity; Diabetes Mellitus, Type 2; Fem

2011
Von Willebrand factor in type 1 diabetes: its production and coronary artery calcification.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:7

    Topics: Adult; Albuminuria; Area Under Curve; Bradykinin; Calcinosis; Coronary Artery Disease; Diabetes Mell

2003
Urinary albumin excretion is associated with impaired flow- and nitroglycerin-mediated brachial artery dilatation in hypertensive adults.
    Journal of human hypertension, 2007, Volume: 21, Issue:3

    Topics: Albuminuria; Brachial Artery; Comorbidity; Female; Humans; Hypertension; Male; Mass Screening; Middl

2007
Noninvasive detection of functional alterations of the arterial wall in IDDM patients with and without microalbuminuria.
    Diabetes care, 1995, Volume: 18, Issue:7

    Topics: Adult; Albuminuria; Blood Pressure; Carotid Arteries; Case-Control Studies; Cholesterol; Cholesterol

1995
Endothelium-dependent and -independent vasodilation of large arteries in normoalbuminuric insulin-dependent diabetes mellitus.
    Arteriosclerosis, thrombosis, and vascular biology, 1996, Volume: 16, Issue:5

    Topics: Adult; Albuminuria; Brachial Artery; Diabetes Mellitus, Type 1; Endothelium, Vascular; Female; Hemod

1996
Macroangiopathy--does it play a role in young people?
    Hormone research, 1998, Volume: 50 Suppl 1

    Topics: Adolescent; Adult; Albuminuria; Brachial Artery; Diabetes Mellitus, Type 1; Diabetic Angiopathies; E

1998
Endothelial dysfunction in Type 2 diabetic subjects with and without microalbuminuria.
    Diabetic medicine : a journal of the British Diabetic Association, 1999, Volume: 16, Issue:10

    Topics: Adult; Albuminuria; Brachial Artery; Cholesterol, HDL; Diabetes Mellitus, Type 2; Endothelium, Vascu

1999
Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria.
    Diabetologia, 2001, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood

2001
Impaired vascular reactivity is present despite normal levels of von Willebrand factor in patients with uncomplicated Type 2 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:6

    Topics: Albuminuria; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Cholesterol; Diabetes Mellitu

2002