nitroglycerin has been researched along with Aging in 82 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the hypothesis that aging selectively impairs endothelium-dependent function, which may be reversible by administration of L-arginine." | 7.69 | Aging-associated endothelial dysfunction in humans is reversed by L-arginine. ( Chauhan, A; More, RS; Mullins, PA; Petch, C; Schofield, PM; Taylor, G, 1996) |
| "Male F344BNF1 hybrid rats (F1 crosses between female Fischer 344 and male Brown Norway rats) aged 3 or 24 months were treated with vehicle (1 ml water/kg, IP) or fluoxetine (10 mg/kg, IP) once a day for 1 day or 27 consecutive days; body weights were recorded daily." | 7.68 | Effects of the selective serotonin reuptake inhibitor fluoxetine on baroreceptor reflex sensitivity and body weight in young and old rats. ( Alper, RH, 1992) |
| "To determine if aging alters venous tone, venous distensibility was measured during control conditions and after the administration of nitroglycerin (0." | 7.67 | Aging reduces venous distensibility and the venodilatory response to nitroglycerin in normal subjects. ( Fanelli, C; Gascho, JA; Zelis, R, 1989) |
| "Acute hemodynamic effects of intravenous nitroglycerin (NTG) were assessed in 24 patients with acute myocardial infarction and left ventricular failure, and results were compared between 2 groups of different age (group A--65 years or less, n = 12; group B--75 years or more, n = 12)." | 7.67 | Age-related hemodynamic effects of intravenous nitroglycerin for acute myocardial infarction and left ventricular failure. ( Burgisser, C; Di Bari, M; Ferrucci, L; Fumagalli, S; Marchionni, N; Moschi, G; Paoletti, M; Salani, B; Schneeweiss, A, 1988) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 5.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| " Using a high-resolution ultrasound, the diameter of the brachial artery at rest and during reactive hyperemia (flow-mediated dilatation, FMD%: endothelial-dependent stimulus to vasodilatation), as well as after sublingual administration of nitroglycerin (NTG%: endothelium-independent vasodilatation), was measured." | 3.74 | Relationship between endothelial function and coronary risk factors in patients with stable coronary artery disease. ( Akcakoyun, M; Barutcu, I; Boztosun, B; Esen, AM; Izgi, A; Karakaya, O; Kargin, R; Kirma, C; Saglam, M; Sonmez, K; Turkmen, M, 2007) |
| " Vasomotor influences of brachial endothelium and brachial smooth muscle function to reactive hyperemia and nitroglycerin (400 microg, sublingual spray) were assessed by noninvasive ultrasound in 66 healthy subjects of different ages (20-82 years)." | 3.70 | Age-related progressive brachial artery endothelial dysfunction precedes the changed carotid and left ventricular geometry in healthy humans. ( Bojic, M; Djuric, D; Petrovic, J; Popovic, Z, 1999) |
| "To determine how arterial baroreflex gains for sympathetic nerve activity are affected by aging, muscle sympathetic nerve activity (MSNA) from the tibial nerve was monitored by microneurography, and heart rate and blood pressure were recorded for the pressor or depressor responses to intravenous injections of phenylephrine or nitroglycerin in 22 healthy humans, aged 16 to 57 years old." | 3.69 | Effects of aging on the arterial baroreflex control of muscle sympathetic nerve activity in healthy subjects. ( Iwase, S; Mano, T; Matsukawa, T; Sugiyama, Y, 1994) |
| "This study investigated the hypothesis that aging selectively impairs endothelium-dependent function, which may be reversible by administration of L-arginine." | 3.69 | Aging-associated endothelial dysfunction in humans is reversed by L-arginine. ( Chauhan, A; More, RS; Mullins, PA; Petch, C; Schofield, PM; Taylor, G, 1996) |
| "Male F344BNF1 hybrid rats (F1 crosses between female Fischer 344 and male Brown Norway rats) aged 3 or 24 months were treated with vehicle (1 ml water/kg, IP) or fluoxetine (10 mg/kg, IP) once a day for 1 day or 27 consecutive days; body weights were recorded daily." | 3.68 | Effects of the selective serotonin reuptake inhibitor fluoxetine on baroreceptor reflex sensitivity and body weight in young and old rats. ( Alper, RH, 1992) |
| "Acute hemodynamic effects of intravenous nitroglycerin (NTG) were assessed in 24 patients with acute myocardial infarction and left ventricular failure, and results were compared between 2 groups of different age (group A--65 years or less, n = 12; group B--75 years or more, n = 12)." | 3.67 | Age-related hemodynamic effects of intravenous nitroglycerin for acute myocardial infarction and left ventricular failure. ( Burgisser, C; Di Bari, M; Ferrucci, L; Fumagalli, S; Marchionni, N; Moschi, G; Paoletti, M; Salani, B; Schneeweiss, A, 1988) |
| " Since GDNs have an effect on haemodynamic function, pharmacokinetic analyses that include the parent drug as well as the metabolites are important." | 2.42 | Clinical pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its metabolites. ( Hashimoto, S; Kobayashi, A, 2003) |
| "Nitroglycerin (NTG) was used to assess endothelium-independent vasodilation in all three conditions." | 1.33 | Sympathetic nervous system contributes to the age-related impairment of flow-mediated dilation of the superficial femoral artery. ( de Groot, P; Hopman, MT; Kooijman, M; Smits, P; Thijssen, DH, 2006) |
| "The aim of this study was to assess the effect of chronic administration of L-arginine (LA) on vascular functions as well as its age-related changes." | 1.32 | Age-related changes in the protective effect of chronic administration of L-arginine on post-ischemic recovery of endothelial function. ( Al-Ruzzeh, S; Amrani, M; Chester, AH; Dewar, A; Nakamura, K; Rothery, S; Severs, NJ; Yacoub, MH, 2003) |
| " Nitroglycerin pre-exposure (10 microM for 30 min) provoked a significant shift to the right of the dose-response curve to nitroglycerin in aortae isolated from rats of 8 weeks, 12 and 18 months." | 1.29 | Nitrate tolerance and aging in isolated rat aorta. ( Berkenboom, G; Brékine, D; Fontaine, J; Unger, P, 1993) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 1.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| " Dose-response relationships to acetylcholine were not different between groups, except at the lowest concentration (-8 log M) where young dogs had enhanced relaxation responses." | 1.28 | Effects of increasing age on vascular responses of the in vivo femoral artery of adult beagles. ( Kaiser, L; Ptu, S, 1992) |
| " Thus, the enhanced efficacy of GTN in advanced age seems to stem mainly from pharmacodynamic changes, which may be the consequence of dampened baroreceptor reflexes, as suggested by a lower heart rate increase per unitary fall in systolic arterial pressure observed in group B (0." | 1.28 | Age-related changes in the pharmacodynamics of intravenous glyceryl trinitrate. ( Boncinelli, L; Bürgisser, C; Di Bari, M; Ferrucci, L; Fumagalli, S; Marchionni, N; Moschi, G; Paoletti, M; Salani, B, 1990) |
| " A dorsal hand vein was preconstricted with submaximally effective doses of phenylephrine and a dose-response curve with nitroglycerin was established." | 1.27 | Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans. ( Blaschke, TF; Eichler, HG; Hiremath, A; Hoffman, BB; Katzir, D, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (34.15) | 18.7374 |
| 1990's | 24 (29.27) | 18.2507 |
| 2000's | 21 (25.61) | 29.6817 |
| 2010's | 7 (8.54) | 24.3611 |
| 2020's | 2 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Shields, KL | 1 |
| Jarrett, CL | 1 |
| Bisconti, AV | 1 |
| Park, SH | 1 |
| Craig, JC | 1 |
| Broxterman, RM | 1 |
| Richardson, RS | 1 |
| Maruhashi, T | 1 |
| Kajikawa, M | 1 |
| Kishimoto, S | 1 |
| Hashimoto, H | 1 |
| Takaeko, Y | 1 |
| Yamaji, T | 1 |
| Harada, T | 1 |
| Hashimoto, Y | 1 |
| Han, Y | 1 |
| Aibara, Y | 1 |
| Yusoff, FM | 1 |
| Hidaka, T | 1 |
| Chayama, K | 1 |
| Nakashima, A | 1 |
| Goto, C | 1 |
| Kihara, Y | 1 |
| Higashi, Y | 1 |
| Moerman, A | 1 |
| Bové, T | 1 |
| François, K | 1 |
| Jacobs, S | 1 |
| Deblaere, I | 1 |
| Wouters, P | 1 |
| De Hert, S | 1 |
| Papalia, R | 1 |
| Moro, L | 1 |
| Franceschi, F | 1 |
| Albo, E | 1 |
| D'Adamio, S | 1 |
| Di Martino, A | 1 |
| Vadalà, G | 1 |
| Faldini, C | 1 |
| Denaro, V | 1 |
| Tomiyama, Y | 1 |
| Yoshinaga, K | 1 |
| Fujii, S | 1 |
| Ochi, N | 1 |
| Inoue, M | 2 |
| Nishida, M | 1 |
| Aziki, K | 1 |
| Horie, T | 1 |
| Katoh, C | 1 |
| Tamaki, N | 1 |
| Black, MA | 1 |
| Cable, NT | 1 |
| Thijssen, DH | 2 |
| Green, DJ | 1 |
| Zachrisson, H | 1 |
| Lindenberger, M | 1 |
| Hallman, D | 1 |
| Ekman, M | 1 |
| Neider, D | 1 |
| Länne, T | 1 |
| Nguyen, PK | 1 |
| Terashima, M | 1 |
| Fair, JM | 1 |
| Varady, A | 1 |
| Taylor-Piliae, RE | 1 |
| Iribarren, C | 1 |
| Go, AS | 1 |
| Haskell, WL | 1 |
| Hlatky, MA | 1 |
| Fortmann, SP | 1 |
| McConnell, MV | 1 |
| Marlatt, KL | 1 |
| McCue, MC | 1 |
| Kelly, AS | 1 |
| Metzig, AM | 1 |
| Steinberger, J | 1 |
| Dengel, DR | 1 |
| Cecelja, M | 1 |
| Jiang, B | 1 |
| Spector, TD | 1 |
| Chowienczyk, P | 1 |
| Singh, N | 1 |
| Graves, J | 1 |
| Taylor, PD | 1 |
| MacAllister, RJ | 1 |
| Singer, DR | 1 |
| Millasseau, SC | 2 |
| Kelly, RP | 2 |
| Ritter, JM | 2 |
| Chowienczyk, PJ | 2 |
| Nauli, SM | 1 |
| White, CR | 1 |
| Hull, AD | 1 |
| Pearce, WJ | 2 |
| Hashimoto, S | 1 |
| Kobayashi, A | 1 |
| Nakamura, K | 1 |
| Al-Ruzzeh, S | 1 |
| Chester, AH | 1 |
| Dewar, A | 1 |
| Rothery, S | 1 |
| Severs, NJ | 1 |
| Yacoub, MH | 1 |
| Amrani, M | 1 |
| Matsukawa, T | 1 |
| Sugiyama, Y | 1 |
| Iwase, S | 1 |
| Mano, T | 1 |
| COSTANZO, F | 2 |
| MIGLIORINI, G | 2 |
| PIETRA, R | 2 |
| BENDER, AD | 1 |
| Franzoni, F | 2 |
| Ghiadoni, L | 2 |
| Galetta, F | 2 |
| Plantinga, Y | 2 |
| Lubrano, V | 1 |
| Huang, Y | 1 |
| Salvetti, G | 1 |
| Regoli, F | 1 |
| Taddei, S | 2 |
| Santoro, G | 2 |
| Salvetti, A | 1 |
| Young, CN | 1 |
| Stillabower, ME | 1 |
| DiSabatino, A | 1 |
| Farquhar, WB | 1 |
| de Groot, P | 1 |
| Kooijman, M | 1 |
| Smits, P | 1 |
| Hopman, MT | 1 |
| Parker, BA | 2 |
| Ridout, SJ | 2 |
| Proctor, DN | 2 |
| Rossi, M | 1 |
| Prattichizzo, F | 1 |
| Carpi, A | 1 |
| Smithmyer, SL | 1 |
| Jarvis, SS | 1 |
| Pawelczyk, JA | 1 |
| Kirma, C | 1 |
| Akcakoyun, M | 1 |
| Esen, AM | 1 |
| Barutcu, I | 1 |
| Karakaya, O | 1 |
| Saglam, M | 1 |
| Kargin, R | 1 |
| Turkmen, M | 1 |
| Boztosun, B | 1 |
| Izgi, A | 1 |
| Sonmez, K | 1 |
| Verheyden, B | 1 |
| Gisolf, J | 1 |
| Beckers, F | 1 |
| Karemaker, JM | 1 |
| Wesseling, KH | 1 |
| Aubert, AE | 1 |
| Wieling, W | 1 |
| Sherwood, A | 1 |
| Bower, JK | 1 |
| McFetridge-Durdle, J | 1 |
| Blumenthal, JA | 1 |
| Newby, LK | 1 |
| Hinderliter, AL | 1 |
| Heiss, C | 1 |
| Sievers, RE | 1 |
| Amabile, N | 1 |
| Momma, TY | 1 |
| Chen, Q | 1 |
| Natarajan, S | 1 |
| Yeghiazarians, Y | 1 |
| Springer, ML | 1 |
| Mayhan, WG | 2 |
| Arrick, DM | 1 |
| Sharpe, GM | 1 |
| Sun, H | 1 |
| Nicolas, G | 1 |
| Bouhour, JB | 1 |
| Godin, JF | 1 |
| Shimzu, T | 1 |
| Antonaccio, MJ | 1 |
| Cavaliere, T | 1 |
| Cote, D | 1 |
| Ioannides, C | 1 |
| Parke, DV | 1 |
| Taylor, IW | 1 |
| Garbán, H | 1 |
| Vernet, D | 1 |
| Freedman, A | 1 |
| Rajfer, J | 1 |
| González-Cadavid, N | 1 |
| Corretti, MC | 1 |
| Plotnick, GD | 1 |
| Vogel, RA | 1 |
| Celermajer, DS | 1 |
| Sorensen, KE | 1 |
| Spiegelhalter, DJ | 1 |
| Georgakopoulos, D | 1 |
| Robinson, J | 1 |
| Deanfield, JE | 1 |
| Unger, P | 1 |
| Berkenboom, G | 1 |
| Brékine, D | 1 |
| Fontaine, J | 1 |
| Polio, J | 1 |
| Sieber, CC | 1 |
| Lerner, E | 1 |
| Groszmann, RJ | 1 |
| Tasker, RC | 1 |
| Sahota, SK | 1 |
| Williams, SR | 1 |
| Li, YM | 1 |
| Steffes, M | 1 |
| Donnelly, T | 1 |
| Liu, C | 1 |
| Fuh, H | 2 |
| Basgen, J | 1 |
| Bucala, R | 2 |
| Vlassara, H | 2 |
| Chauhan, A | 1 |
| More, RS | 1 |
| Mullins, PA | 1 |
| Taylor, G | 1 |
| Petch, C | 1 |
| Schofield, PM | 1 |
| Takazawa, K | 1 |
| Tanaka, N | 1 |
| Fujita, M | 1 |
| Matsuoka, O | 1 |
| Saiki, T | 1 |
| Aikawa, M | 1 |
| Tamura, S | 1 |
| Ibukiyama, C | 1 |
| Jensen-Urstad, K | 2 |
| Bouvier, F | 1 |
| Jensen-Urstad, M | 1 |
| Djuric, D | 1 |
| Popovic, Z | 1 |
| Petrovic, J | 1 |
| Bojic, M | 1 |
| Frauchiger, B | 1 |
| Nussbaumer, P | 1 |
| Hugentobler, M | 1 |
| Staub, D | 1 |
| Johansson, J | 1 |
| Kimura, Y | 1 |
| Matsumoto, M | 1 |
| Miyauchi, E | 1 |
| Deng, YB | 1 |
| Iwai, K | 1 |
| Hattori, H | 1 |
| Teraoka, K | 1 |
| Pagani, M | 1 |
| Mirsky, I | 1 |
| Baig, H | 1 |
| Manders, WT | 1 |
| Kerkhof, P | 1 |
| Vatner, SF | 1 |
| Burch, GE | 1 |
| Parker, RJ | 1 |
| Berkowitz, BA | 2 |
| Lee, CH | 2 |
| Denckla, WD | 1 |
| Short, RD | 1 |
| Dacre, JC | 1 |
| Lee, CC | 1 |
| Fleisch, JH | 1 |
| Hooker, CS | 1 |
| Feldman, RD | 1 |
| Makita, Z | 1 |
| Krungkrai, S | 1 |
| Cerami, A | 1 |
| Sønksen, J | 1 |
| Biering-Sørensen, F | 1 |
| Tonkin, A | 1 |
| Wing, L | 1 |
| Wight, LJ | 1 |
| VandenBurg, MJ | 1 |
| Potter, CE | 1 |
| Freeth, CJ | 1 |
| Kaiser, L | 1 |
| Ptu, S | 1 |
| Alper, RH | 1 |
| Longo, LD | 1 |
| Hajduczok, G | 1 |
| Chapleau, MW | 1 |
| Johnson, SL | 1 |
| Abboud, FM | 1 |
| Faraci, FM | 1 |
| Baumbach, GL | 1 |
| Heistad, DD | 1 |
| Alpert, JS | 1 |
| Marchionni, N | 2 |
| Ferrucci, L | 2 |
| Fumagalli, S | 2 |
| Boncinelli, L | 1 |
| Salani, B | 2 |
| Di Bari, M | 2 |
| Moschi, G | 2 |
| Paoletti, M | 2 |
| Bürgisser, C | 2 |
| Tsujimoto, G | 1 |
| Hoffman, BB | 3 |
| Gascho, JA | 1 |
| Fanelli, C | 1 |
| Zelis, R | 1 |
| Marks, RG | 1 |
| Hale, WE | 1 |
| Moore, MT | 1 |
| May, FE | 1 |
| Stewart, RB | 1 |
| Renlund, DG | 1 |
| Gerstenblith, G | 1 |
| Bennett, A | 1 |
| Melhuish, PB | 1 |
| Stamford, IF | 1 |
| Pan, HY | 1 |
| Pershe, RA | 1 |
| Blaschke, TF | 2 |
| Markarian, SS | 1 |
| Chadwick, RS | 1 |
| Goldstein, DS | 1 |
| Keiser, HR | 1 |
| Eichler, HG | 1 |
| Hiremath, A | 1 |
| Katzir, D | 1 |
| Schneeweiss, A | 1 |
| Jiron, MI | 1 |
| Lee, SS | 1 |
| Cerini, R | 1 |
| Pugliese, D | 1 |
| Hadengue, A | 1 |
| Lebrec, D | 1 |
| Russek, HI | 1 |
| Cohen, ML | 1 |
| Maggi, GC | 1 |
| Morozov, KA | 1 |
| Koriakin, NN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Biological Sex and Age on Cerebral Blood Flow and Vessel Function During Exercise: a Pilot Study[NCT05864950] | 85 participants (Anticipated) | Observational | 2023-04-18 | Enrolling by invitation | |||
| Improving Blood Pressure and Cardiovascular Risk With Resistance Exercise in African Americans[NCT03016351] | 140 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638] | Early Phase 1 | 80 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| MRI Biomarkers of Risk in Sedentary and Exercise Trained Humans[NCT02729428] | 71 participants (Actual) | Observational | 2016-04-30 | Completed | |||
| DUAL Pathway Inhibition (Low-dose Rivaroxaban and Aspirin) as Compared to Aspirin Only to Improve Endothelial Function in Peripheral Artery Disease.[NCT04218656] | Phase 4 | 159 participants (Actual) | Interventional | 2020-06-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for nitroglycerin and Aging
| Article | Year |
|---|---|
Endothelial dysfunction and tendinopathy: how far have we come?
Topics: Aging; Animals; Apoptosis; Biomarkers; Cumulative Trauma Disorders; Endothelium, Vascular; Enzyme In | 2013 |
Clinical pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its metabolites.
Topics: Administration, Topical; Aging; Biotransformation; Exercise; Humans; Models, Biological; Nitroglycer | 2003 |
[Strategy of the medical treatment of angina pectoris].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Amiodarone; Angina Pectoris; Calcium Channel Blocke | 1983 |
Nitrate therapy in the elderly.
Topics: Aged; Aging; Bradycardia; Coronary Disease; Half-Life; Humans; Hypotension; Isosorbide Dinitrate; Ni | 1990 |
Angina: current approaches to diagnosis, drug therapy, and surgical referral.
Topics: Adrenergic beta-Antagonists; Aged; Aging; Angina Pectoris; Angioplasty, Balloon; Calcium Channel Blo | 1986 |
[Echocardiography under physical loading].
Topics: Adult; Aging; Coronary Disease; Echocardiography; Exercise Test; Heart; Heart Failure; Hemodynamics; | 1986 |
7 trials available for nitroglycerin and Aging
| Article | Year |
|---|---|
Society of cardiovascular anesthesiologists: the effect of blood pressure regulation during aortic coarctation repair on brain, kidney, and muscle oxygen saturation measured by near-infrared spectroscopy: a randomized, clinical trial.
Topics: Aging; Anesthesia, Intravenous; Aortic Coarctation; Blood Pressure; Brain Chemistry; Cardiac Surgica | 2013 |
Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Area Under Curve; Ascorbic Acid; Bradykinin; D | 2002 |
The vascular impact of aging and vasoactive drugs: comparison of two digital volume pulse measurements.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Blood Volume Determination; Fingers; Humans; Inf | 2003 |
Ambulatory blood pressure monitoring and endothelium-dependent vasodilation in the elderly athletes.
Topics: Aged; Aging; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Endothelium, Va | 2006 |
Ambulatory blood pressure monitoring and endothelium-dependent vasodilation in the elderly athletes.
Topics: Aged; Aging; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Endothelium, Va | 2006 |
Ambulatory blood pressure monitoring and endothelium-dependent vasodilation in the elderly athletes.
Topics: Aged; Aging; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Endothelium, Va | 2006 |
Ambulatory blood pressure monitoring and endothelium-dependent vasodilation in the elderly athletes.
Topics: Aged; Aging; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Endothelium, Va | 2006 |
Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.
Topics: Administration, Cutaneous; Age Factors; Aged; Aged, 80 and over; Aging; Blood Flow Velocity; Brachia | 2007 |
Noninvasive detection of endothelial dysfunction in elderly with NIDDM by ultrasonography.
Topics: Administration, Sublingual; Aged; Aging; Arteriosclerosis; Blood Flow Velocity; Brachial Artery; Dia | 2001 |
Aging and susceptibility to drug-induced orthostatic hypotension.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Bendroflumethiazi | 1992 |
69 other studies available for nitroglycerin and Aging
| Article | Year |
|---|---|
Preserved endothelium-independent vascular function with aging in men and women: evidence from the peripheral and cerebral vasculature.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Female; Humans; Male; Nitroglycerin; Vas | 2023 |
Vascular function is further impaired in subjects aged 80 years or older.
Topics: Aged; Aged, 80 and over; Aging; Brachial Artery; Female; Humans; Male; Middle Aged; Nitroglycerin; P | 2020 |
Accurate quantitative measurements of brachial artery cross-sectional vascular area and vascular volume elastic modulus using automated oscillometric measurements: comparison with brachial artery ultrasound.
Topics: Adult; Aging; Anatomy, Cross-Sectional; Brachial Artery; Elastic Modulus; Female; Humans; Image Proc | 2015 |
Impact of age, sex, and exercise on brachial artery flow-mediated dilatation.
Topics: Adult; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Female; Humans; Male; Nitric Oxide; | 2009 |
Diameter and compliance of the greater saphenous vein - effect of age and nitroglycerine.
Topics: Adult; Aged; Aging; Elastic Modulus; Humans; Male; Nitroglycerin; Saphenous Vein; Vasodilator Agents | 2011 |
Physical activity in older subjects is associated with increased coronary vasodilation: the ADVANCE study.
Topics: Age Factors; Aged; Aging; California; Chi-Square Distribution; Coronary Circulation; Coronary Vessel | 2011 |
Endothelium-independent dilation in children and adolescents.
Topics: Administration, Sublingual; Adolescent; Age Factors; Aging; Analysis of Variance; Brachial Artery; C | 2011 |
Progression of central pulse pressure over 1 decade of aging and its reversal by nitroglycerin a twin study.
Topics: Aging; Aorta, Abdominal; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, D | 2012 |
Determination of age-related increases in large artery stiffness by digital pulse contour analysis.
Topics: Adult; Aged; Aging; Aorta; Arteries; Blood Flow Velocity; Blood Pressure; Compliance; Female; Finger | 2002 |
Maturation alters cyclic nucleotide and relaxation responses to nitric oxide donors in ovine cerebral arteries.
Topics: Aging; Animals; Animals, Newborn; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Dose-Response Relations | 2003 |
Age-related changes in the protective effect of chronic administration of L-arginine on post-ischemic recovery of endothelial function.
Topics: Aging; Animals; Arginine; Endothelium, Vascular; Male; Models, Animal; Muscle, Smooth, Vascular; Myo | 2003 |
Effects of aging on the arterial baroreflex control of muscle sympathetic nerve activity in healthy subjects.
Topics: Adolescent; Adult; Aging; Baroreflex; Blood Pressure; Carotid Sinus; Female; Heart Rate; Humans; Mal | 1994 |
[The effort test & the nitroglycerin test in the aged].
Topics: Aged; Aging; Electrocardiography; Humans; Nitrates; Nitroglycerin | 1959 |
[Changes induced in the electrocardiogram of the aged by the administration of nitroglycerin].
Topics: Aged; Aging; Electrocardiography; Humans; Nitrates; Nitroglycerin; Pharmaceutical Preparations | 1959 |
PHARMACOLOGIC ASPECTS OF AGING: FURTHER OBSERVATIONS.
Topics: Acetylcholine; Aging; Antitubercular Agents; Drug Tolerance; Epinephrine; Geriatrics; Hormones; Meta | 1964 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men.
Topics: Adult; Aged; Aging; Brachial Artery; Endothelium, Vascular; Exercise; Free Radical Scavengers; Human | 2005 |
Venous smooth muscle tone and responsiveness in older adults.
Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Compliance; Female; Forearm; Humans; Leg; Male; Midd | 2006 |
Sympathetic nervous system contributes to the age-related impairment of flow-mediated dilation of the superficial femoral artery.
Topics: Adult; Aged; Aging; Cold Temperature; Endothelium, Vascular; Exercise; Exercise Test; Femoral Artery | 2006 |
Age and flow-mediated dilation: a comparison of dilatory responsiveness in the brachial and popliteal arteries.
Topics: Adult; Aged; Aging; Arm; Brachial Artery; Endothelium, Vascular; Female; Humans; Leg; Middle Aged; M | 2006 |
Evidence for reduced sympatholysis in leg resistance vasculature of healthy older women.
Topics: Administration, Sublingual; Adult; Age Factors; Aged; Aging; Blood Flow Velocity; Cold Temperature; | 2007 |
Relationship between endothelial function and coronary risk factors in patients with stable coronary artery disease.
Topics: Administration, Sublingual; Aged; Aging; Brachial Artery; Coronary Artery Disease; Diabetic Angiopat | 2007 |
Impact of age on the vasovagal response provoked by sublingual nitroglycerine in routine tilt testing.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Baroreflex; Blood Pressure; Cardiac Output; Female; Hea | 2007 |
In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound.
Topics: Adenosine; Aging; Animals; Dose-Response Relationship, Drug; Echocardiography; Femoral Artery; Hindl | 2008 |
Age-related alterations in reactivity of cerebral arterioles: role of oxidative stress.
Topics: Acetylcholine; Adenosine Diphosphate; Aging; Animals; Arterioles; Brain; Cerebrovascular Circulation | 2008 |
[Clinical assessment of coronary vascular stiffness and tone by pressure-diameter relationships of the coronary arteries].
Topics: Adult; Aged; Aging; Angina Pectoris; Angiography; Blood Pressure; Computers; Coronary Angiography; C | 1984 |
Ontogenesis of hypertension and responsiveness to antihypertensive agents in spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Guanethidine; Heart Rate; Hypertensi | 1980 |
Elimination of glyceryl trinitrate: effects of sex, age, species and route of administration.
Topics: Aging; Animals; Cricetinae; Female; Ferrets; Guinea Pigs; Half-Life; Male; Nitroglycerin; Rabbits; R | 1982 |
Effect of aging on nitric oxide-mediated penile erection in rats.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Egtazic Acid | 1995 |
The effects of age and gender on brachial artery endothelium-dependent vasoactivity are stimulus-dependent.
Topics: Adult; Age Factors; Aging; Arteriosclerosis; Blood Flow Velocity; Blood Pressure; Brachial Artery; C | 1995 |
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women.
Topics: Adolescent; Adult; Aged; Aging; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Nitroglyce | 1994 |
Nitrate tolerance and aging in isolated rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniqu | 1993 |
Cardiovascular hyporesponsiveness to norepinephrine, propranolol and nitroglycerin in portal-hypertensive and aged rats.
Topics: Aging; Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate; | 1993 |
Bioenergetic recovery following ischemia in brain slices studied by 31P-NMR spectroscopy: differential age effect of depolarization mediated by endogenous nitric oxide.
Topics: Adenosine Triphosphate; Aging; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High | 1996 |
Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine.
Topics: Acetylcholine; Aging; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; Creatinine; Enzyme | 1996 |
Aging-associated endothelial dysfunction in humans is reversed by L-arginine.
Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Va | 1996 |
Assessment of vasoactive agents and vascular aging by the second derivative of photoplethysmogram waveform.
Topics: Aged; Aging; Angiotensin II; Aorta; Blood Pressure; Female; Humans; Male; Middle Aged; Nitroglycerin | 1998 |
Preserved vascular reactivity in elderly male athletes.
Topics: Aged; Aging; Arteriosclerosis; Blood Pressure; Body Mass Index; Brachial Artery; Carotid Artery Dise | 1999 |
Age-related progressive brachial artery endothelial dysfunction precedes the changed carotid and left ventricular geometry in healthy humans.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Brachial Artery; Carotid Arteries; Diastole; | 1999 |
Duplex sonographic registration of age and diabetes-related loss of renal vasodilatory response to nitroglycerine.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arterioles; Diabetes Mellitus, Type 1; Diabetes Mellitus, Typ | 2000 |
Gender difference in age-related changes in vascular function.
Topics: Adult; Aging; Blood Cell Count; Blood Pressure; Body Mass Index; Brachial Artery; Cardiovascular Dis | 2001 |
[A study on evaluation of the cardiovascular regulation to tilting by noninvasive method. 3. Effects of nitroglycerin on the cardiovascular response to tilting (author's transl)].
Topics: Adult; Aged; Aging; Evaluation Studies as Topic; Hemodynamics; Humans; Hypertension; Male; Middle Ag | 1978 |
Effects of age on aortic pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Elasticity; Female; Hemodyn | 1979 |
Medical management of angina pectoris.
Topics: Aging; Angina Pectoris; Arteriosclerosis; Coronary Disease; Diet; Humans; Hypnotics and Sedatives; N | 1979 |
Vascular relaxation, aging and thyroid hormones.
Topics: Aging; Animals; Aorta; Blood Vessels; Dose-Response Relationship, Drug; Female; Hypophysectomy; Isop | 1978 |
A species and developmental comparison of trinitroglycerin metabolism in vitro.
Topics: Adult; Aged; Aging; Animals; Dogs; Embryo, Mammalian; Female; Gestational Age; Haplorhini; Humans; I | 1977 |
The relationship between age and relaxation of vascular smooth muscle in the rabbit and rat.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Musc | 1976 |
A low-sodium diet corrects the defect in beta-adrenergic response in older subjects.
Topics: Adenylyl Cyclases; Aged; Aging; Blood Pressure; Blood Vessels; Diet, Sodium-Restricted; Electrolytes | 1992 |
Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: a model for diabetic and aging complications.
Topics: Acetylcholine; Aging; Animals; Blood Pressure; Capillary Permeability; Diabetes Mellitus, Experiment | 1992 |
Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured.
Topics: Administration, Cutaneous; Adult; Aging; Erectile Dysfunction; Humans; Male; Middle Aged; Nitroglyce | 1992 |
A large scale comparative study in general practice with nitroglycerin spray and tablet formulations in elderly patients with angina pectoris.
Topics: Administration, Inhalation; Administration, Sublingual; Aged; Aging; Angina Pectoris; Chi-Square Dis | 1992 |
Effects of increasing age on vascular responses of the in vivo femoral artery of adult beagles.
Topics: Acetylcholine; Aging; Animals; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Male; | 1992 |
Effects of the selective serotonin reuptake inhibitor fluoxetine on baroreceptor reflex sensitivity and body weight in young and old rats.
Topics: Aging; Animals; Blood Pressure; Body Weight; Fluoxetine; Heart Rate; Male; Nitroglycerin; Phenylephr | 1992 |
Developmental aspects of endothelial function.
Topics: Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Calcimycin; Cerebral Arteries; Cerebrovascu | 1991 |
Increase in sympathetic activity with age. I. Role of impairment of arterial baroreflexes.
Topics: Aging; Anesthesia; Animals; Arteries; Atropine; Blood Pressure; Dogs; Heart Rate; Kidney; Male; Nitr | 1991 |
Effects of aging on responses of cerebral arterioles.
Topics: Acetylcholine; Adenosine Diphosphate; Aging; Animals; Arterioles; Bradykinin; Cerebrovascular Circul | 1990 |
Age-related changes in the pharmacodynamics of intravenous glyceryl trinitrate.
Topics: Aged; Aging; Hemodynamics; Humans; Injections, Intravenous; Middle Aged; Nitroglycerin | 1990 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
Aging reduces venous distensibility and the venodilatory response to nitroglycerin in normal subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Elasticity; Female; Forearm; Hemodynamics; Humans; Male; Midd | 1989 |
Resting heart rates in an ambulatory elderly population: an evaluation of age, sex, symptoms, and medication.
Topics: Aged; Aging; Blood Pressure; Digoxin; Female; Heart Rate; Humans; Male; Nitroglycerin; Propranolol; | 1989 |
Nitrates do not affect prostacyclin formation by rat arteries: this is unrelated to increased vascular prostacyclin formation with age.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Arteries; Epoprostenol; In Vitro Techniques; Isosorbid | 1987 |
Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.
Topics: Adult; Aged; Aging; Cyclic AMP; Humans; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, | 1986 |
Pulse-wave model of brachial arterial pressure modulation in aging and hypertension.
Topics: Adult; Aging; Atropine; Blood Pressure; Brachial Artery; Heart Rate; Humans; Hypertension; Mathemati | 1986 |
Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans.
Topics: Adult; Aged; Aging; Dose-Response Relationship, Drug; Humans; Male; Methods; Middle Aged; Nitroglyce | 1987 |
Age-related hemodynamic effects of intravenous nitroglycerin for acute myocardial infarction and left ventricular failure.
Topics: Aged; Aging; Blood Pressure; Hemodynamics; Humans; Infusions, Intravenous; Middle Aged; Myocardial I | 1988 |
Effects of nitroglycerin on forearm haemodynamics in patients with cirrhosis.
Topics: Adolescent; Adult; Aged; Aging; Female; Forearm; Hemodynamics; Humans; Liver Cirrhosis; Male; Middle | 1988 |
The "natural" history of severe angina pectoris with intensive medical therapy alone: a five year prospective study of 133 patients.
Topics: Adult; Aged; Aging; Angina Pectoris; Atrial Fibrillation; Cardiomegaly; Cerebrovascular Disorders; D | 1974 |
Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.
Topics: Aging; Animals; Aorta, Thoracic; Benzyl Compounds; Bucladesine; Cyclic AMP; Cyclic GMP; Dose-Respons | 1974 |
[Prevention and general therapy of coronary insufficiency].
Topics: Aged; Aging; Angina Pectoris; Anticoagulants; Coronary Disease; Ethanolamines; Humans; Middle Aged; | 1971 |
[Reactivity of the circulatory system in middle-aged and elderly persons].
Topics: Adult; Aged; Aging; Arteriosclerosis; Blood Circulation; Blood Pressure; Blood Vessels; Cardiac Outp | 1972 |