Page last updated: 2024-11-01

nitroglycerin and Adenocarcinoma, Basal Cell

nitroglycerin has been researched along with Adenocarcinoma, Basal Cell in 7 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Research Excerpts

ExcerptRelevanceReference
"Seventeen patients with operable lung adenocarcinoma and stable angina pectoris were selected to investigate the effects of nitroglycerin on immunoreactivity for hypoxia-inducible factor 1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF), P-glycoprotein (P-gp), the production of which is regulated by HIF-1, and p53 proteins in their resected tumor by semiquantitative immunohistochemical analyses."9.12Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma. ( Asada, M; Fuji, H; Inoue, D; Kanda, A; Kaneta, T; Kondo, T; Nakayama, K; Okinaga, S; Sasaki, H; Sasaki, T; Suzuki, S; Suzuki, T; Takai, Y; Watanabe, M; Yamanda, S; Yamaya, M; Yanagihara, K; Yasuda, H; Yoshida, M; Zayasu, K, 2006)
"Seventeen patients with operable lung adenocarcinoma and stable angina pectoris were selected to investigate the effects of nitroglycerin on immunoreactivity for hypoxia-inducible factor 1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF), P-glycoprotein (P-gp), the production of which is regulated by HIF-1, and p53 proteins in their resected tumor by semiquantitative immunohistochemical analyses."5.12Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma. ( Asada, M; Fuji, H; Inoue, D; Kanda, A; Kaneta, T; Kondo, T; Nakayama, K; Okinaga, S; Sasaki, H; Sasaki, T; Suzuki, S; Suzuki, T; Takai, Y; Watanabe, M; Yamanda, S; Yamaya, M; Yanagihara, K; Yasuda, H; Yoshida, M; Zayasu, K, 2006)
"Hypoxia is also associated with human prostate cancers, which are highly resistant to chemotherapy."1.32Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate. ( Adams, MA; Frederiksen, LJ; Graham, CH; Heaton, JP; Maxwell, LR; Siemens, DR, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Illum, H1
Wang, DH1
Dowell, JE1
Hittson, WJ1
Torrisi, JR1
Meyer, J1
Huerta, S1
Siemens, DR2
Hu, N1
Sheikhi, AK1
Chung, E1
Frederiksen, LJ2
Pross, H1
Graham, CH2
Nagai, H1
Yasuda, H2
Hatachi, Y1
Xue, D1
Sasaki, T2
Yamaya, M2
Sakamori, Y1
Togashi, Y1
Masago, K1
Ito, I1
Kim, YH1
Mio, T1
Mishima, M1
Heaton, JP1
Maxwell, LR1
Adams, MA1
Nakayama, K1
Watanabe, M1
Suzuki, S1
Fuji, H1
Okinaga, S1
Kanda, A1
Zayasu, K1
Asada, M1
Suzuki, T1
Yoshida, M1
Yamanda, S1
Inoue, D1
Kaneta, T1
Kondo, T1
Takai, Y1
Sasaki, H1
Yanagihara, K1
Lagergren, J1
Bergström, R1
Adami, HO1
Nyrén, O1
Kontturi, M1
Sotaniemi, E1
Ahlqvist, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Exercise Training on Tumor Vascularity and Response to Neoadjuvant Therapy in Operable Breast Cancer: A Phase I-II Study[NCT00405678]Phase 1/Phase 223 participants (Actual)Interventional2006-09-30Completed
A Prospective Study To Define The Role Of Various Factors In Development And Progression Of Gastroesophageal Reflux Disease (GERD) And Barrett's Esophagus And The Creation Of A Registry.[NCT00574327]3,000 participants (Anticipated)Observational2006-01-31Recruiting
Barrett's Esophagus Study (BEST) Trial - a Multi-Center and Endoscopic Outcomes Project[NCT00586404]1,250 participants (Actual)Observational2007-11-30Terminated (stopped due to lack of enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nitroglycerin and Adenocarcinoma, Basal Cell

ArticleYear
Phase I dose escalation trial of nitroglycerin in addition to 5-fluorouracil and radiation therapy for neoadjuvant treatment of operable rectal cancer.
    Surgery, 2015, Volume: 158, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2015
Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding

2006

Other Studies

5 other studies available for nitroglycerin and Adenocarcinoma, Basal Cell

ArticleYear
Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Adenocarcinoma; Animals; Cells, Cultured; Histocompatibility Antigens Class I; Humans; Hypoxia; Immu

2008
Nitric oxide (NO) enhances pemetrexed cytotoxicity via NO‑cGMP signaling in lung adenocarcinoma cells in vitro and in vivo.
    International journal of oncology, 2012, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Apo

2012
Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate.
    The Journal of urology, 2003, Volume: 170, Issue:3

    Topics: Adenocarcinoma; Blotting, Western; Cell Cycle; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometr

2003
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
    Annals of internal medicine, 2000, Aug-01, Volume: 133, Issue:3

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell;

2000
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
    Annals of internal medicine, 2000, Aug-01, Volume: 133, Issue:3

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell;

2000
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
    Annals of internal medicine, 2000, Aug-01, Volume: 133, Issue:3

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell;

2000
Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma.
    Annals of internal medicine, 2000, Aug-01, Volume: 133, Issue:3

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Aminophylline; Benzodiazepines; Carcinoma, Squamous Cell;

2000
Liver damage and estrogen therapy of prostatic cancer. Case report.
    Scandinavian journal of urology and nephrology, 1972, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Aged; Blood Glucose; Carbutamide; Diabetes Mellitus; Diethylstilbestrol; Digoxin; Dr

1972