Page last updated: 2024-11-01

nitroglycerin and Acute Coronary Syndrome

nitroglycerin has been researched along with Acute Coronary Syndrome in 26 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Nitroglycerin ointment is commonly used in the treatment of emergency department (ED) patients with suspected acute heart failure (AHF) or suspected acute coronary syndrome (ACS), but its hemodynamic effects in this population are not well described."3.80Hemodynamic effects of nitroglycerin ointment in emergency department patients. ( Dhingra, KR; Diercks, DB; Kurlinkus, C; Mumma, BE, 2014)
"A 51-year-old woman presented with severe chest pain minutes after starting intravenous paclitaxel as a part of the systemic chemotherapy due to ovarian carcinoma."3.75Paclitaxel-induced ST-segment elevations. ( Cinçin, A; Değertekin, M; Gemici, G; Oktay, A, 2009)
"Coronary vasospasm is characterized by transient and reversible vasoconstriction that can cause myocardial ischemia."1.91A Rare Case of Vasospasm Presenting with Acute Coronary Syndrome and Leading to Total Occlusion. ( Güzel, T, 2023)
"High adenosine dose was adequately tolerated by all patients, without requiring infusion discontinuation in any case."1.43Effect of High (200 μg/kg per Minute) Adenosine Dose Infusion on Fractional Flow Reserve Variability. ( Alexopoulos, D; Armylagos, S; Davlouros, P; Koutsogiannis, N; Moulias, A; Salata, P; Tsigkas, G; Xanthopoulou, I, 2016)
"Sex disparities in the diagnosis and treatment of chest pain or suspected angina have been demonstrated in multiple clinical settings."1.36Influence of sex on the out-of-hospital management of chest pain. ( Armstrong, K; Facenda, K; Mechem, CC; Meisel, ZF; Peacock, N; Pollack, CV; Shofer, FS, 2010)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (15.38)29.6817
2010's21 (80.77)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Güzel, T1
Brener, MI1
Tung, J1
Stant, J1
Sayan, OR1
Suh, EH1
Minutello, RM1
Sharma, R1
Brener, SJ1
Melniker, LA1
Moustakakis, EN1
Neuberg, G1
Breen, LM1
Nutovits, R1
Kats, Y1
Amaranto, A1
Pucillo, A1
Kirtane, AJ1
Rabbani, LE1
Roa-Garrido, J1
Gomez-Menchero, AE1
El Amrawy, AM1
Cardenal-Piris, R1
Camacho-Freire, S1
Diaz-Fernandez, JF1
Otsuka, T1
Räber, L1
Francis, RC1
Bubser, F1
Schmidbauer, W1
Spies, CD1
Sörensen, M1
Bosse, G1
Kerner, T1
Mumma, BE1
Dhingra, KR1
Kurlinkus, C1
Diercks, DB1
Chyrchel, M2
Dziewierz, A2
Dudek, D2
Rajpurohit, N1
Ayaz, SZ1
Yee, J1
Khan, MA1
Stys, A1
Kırat, T1
Köse, N1
Kline, KP1
Conti, CR1
Winchester, DE1
Gouda, P1
Bainey, K1
Welsh, R1
Kinsara, AJ1
Alexopoulos, D1
Xanthopoulou, I1
Tsigkas, G1
Koutsogiannis, N1
Salata, P1
Armylagos, S1
Moulias, A1
Davlouros, P1
Tanaka, S1
Yokoyama, C1
Kawamura, I1
Takasugi, N1
Kubota, T1
Ushikoshi, H1
Aoyama, T1
Kawasaki, M1
Nishigaki, K1
Takemura, G1
Minatoguchi, S1
Gemici, G1
Cinçin, A1
Değertekin, M1
Oktay, A1
Overbaugh, KJ1
Meisel, ZF1
Armstrong, K1
Mechem, CC1
Shofer, FS1
Peacock, N1
Facenda, K1
Pollack, CV1
Davie, AP1
O'Connor, RE1
Bossaert, L1
Arntz, HR1
Brooks, SC1
Diercks, D1
Feitosa-Filho, G1
Nolan, JP1
Vanden Hoek, TL1
Walters, DL1
Wong, A1
Welsford, M1
Woolfrey, K1
Morrison, LJ1
Rac, VE1
Bowen, JM1
Schwartz, B1
Perreira, T1
Ryan, W1
Zahn, C1
Chadha, R1
Craig, A1
O'Reilly, D1
Goeree, R1
Peace, A1
De Bruyne, B1
Barbato, E1
Durukan, M1
Aksu, T1
Çolak, A1
Güray, Ü1
Smith, M1
Golwala, H1
Lozano, P1
Finkel, JB1
Marhefka, GD1
Spencker, S1
Schmittel, A1
Westermann, D1
Marek, A1
Schultheiss, HP1
Witzenbichler, B1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).[NCT02350439]Phase 330 participants (Actual)Interventional2015-01-31Completed
Efficacy Evaluation of the HEART Pathway in Emergency Department Patients With Acute Chest Pain[NCT01665521]282 participants (Actual)Interventional2012-09-30Completed
The HEART Pathway: Bridging the Gap Between Operations, Research, and Education[NCT02056964]14,717 participants (Actual)Observational2013-11-30Completed
The Impact of Prehospital 12 Lead ECG With Advanced Emergency Department Notification on Time to In-hospital Reperfusion Strategy in Patients With Acute ST Segment Elevation Myocardial Infarction - A Prospective Study[NCT00747656]446 participants (Actual)Observational2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nitroglycerin and Acute Coronary Syndrome

ArticleYear
Review of acute coronary syndromes: diagnosis and management of unstable angina and non ST-elevation myocardial infarction.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2015, Volume: 68, Issue:2

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Angina, Unstable; Angiotensin-Converting Enzym

2015
Historical perspective and contemporary management of acute coronary syndromes: from MONA to THROMBINS2.
    Postgraduate medicine, 2015, Volume: 127, Issue:8

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspi

2015
Acute coronary syndrome.
    The American journal of nursing, 2009, Volume: 109, Issue:5

    Topics: Acute Coronary Syndrome; Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Biom

2009
Rethinking cocaine-associated chest pain and acute coronary syndromes.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:12

    Topics: Acute Coronary Syndrome; Chest Pain; Cocaine-Related Disorders; Diagnosis, Differential; Electrocard

2011

Other Studies

22 other studies available for nitroglycerin and Acute Coronary Syndrome

ArticleYear
A Rare Case of Vasospasm Presenting with Acute Coronary Syndrome and Leading to Total Occlusion.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2023, Volume: 51, Issue:6

    Topics: Acute Coronary Syndrome; Angina Pectoris; Constriction, Pathologic; Coronary Vasospasm; Humans; Male

2023
An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes.
    Critical pathways in cardiology, 2019, Volume: 18, Issue:4

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Angina, Unstable; Anticoagulants; Chest Pain;

2019
Optical Coherence Tomography Image of Coronary Spasm in a Bioresorbable Vascular Scaffold.
    The Canadian journal of cardiology, 2018, Volume: 34, Issue:3

    Topics: Absorbable Implants; Acute Coronary Syndrome; Coronary Angiography; Coronary Restenosis; Coronary St

2018
Acute coronary syndrome triggered by nitro-resistant triptan-induced coronary spasm.
    European heart journal, 2019, Jun-21, Volume: 40, Issue:24

    Topics: Acute Coronary Syndrome; Aftercare; Calcium Channel Blockers; Coronary Angiography; Coronary Vasospa

2019
Effects of a standard operating procedure on prehospital emergency care of patients presenting with symptoms of the acute coronary syndrome.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2014, Volume: 21, Issue:3

    Topics: Acute Coronary Syndrome; Administration, Sublingual; Adult; Aged; Disease Management; Emergency Medi

2014
Hemodynamic effects of nitroglycerin ointment in emergency department patients.
    The Journal of emergency medicine, 2014, Volume: 47, Issue:2

    Topics: Acute Coronary Syndrome; Adult; Aged; Arterial Pressure; Emergency Service, Hospital; Female; Heart

2014
Recurrent coronary vasospasm-induced acute coronary syndrome complicated by cardiac arrest.
    International journal of cardiology, 2015, Apr-01, Volume: 184

    Topics: Acute Coronary Syndrome; Calcium Channel Blockers; Cardiopulmonary Resuscitation; Cardiovascular Age

2015
A response to "The importance of vasodilator therapy before or during angiography, is ICD necessary or not?" by Tamer Kırat and Nuri Köse.
    International journal of cardiology, 2015, Jul-01, Volume: 190

    Topics: Acute Coronary Syndrome; Calcium Channel Blockers; Coronary Vasospasm; Heart Arrest; Humans; Male; N

2015
The importance of vasodilator therapy before or during angiography, is ICD necessary or not?: A response to Michał Chyrchel et al.
    International journal of cardiology, 2015, Jul-01, Volume: 190

    Topics: Acute Coronary Syndrome; Calcium Channel Blockers; Coronary Vasospasm; Heart Arrest; Humans; Male; N

2015
The Demise of Morphine Oxygen Nitroglycerin Aspirin (MONA).
    The Canadian journal of cardiology, 2016, Volume: 32, Issue:12

    Topics: Acute Coronary Syndrome; Aspirin; Chest Pain; Evidence-Based Emergency Medicine; Humans; Morphine; N

2016
SNAAP to Replace MONA.
    The American journal of cardiology, 2017, 08-01, Volume: 120, Issue:3

    Topics: Acute Coronary Syndrome; Advanced Cardiac Life Support; American Heart Association; Anticoagulants;

2017
Effect of High (200 μg/kg per Minute) Adenosine Dose Infusion on Fractional Flow Reserve Variability.
    Journal of the American Heart Association, 2016, 11-10, Volume: 5, Issue:11

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Arterial Pressure; Coronary Angiography; Coronary Artery D

2016
Conservative medication follow-up for over 20 years of a patient with ischemic heart disease after diagnosis of chronic total occlusion of the 3 main coronary arteries.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:7

    Topics: Acute Coronary Syndrome; Administration, Sublingual; Angina Pectoris; Antihypertensive Agents; Chron

2008
Paclitaxel-induced ST-segment elevations.
    Clinical cardiology, 2009, Volume: 32, Issue:6

    Topics: Acute Coronary Syndrome; Administration, Sublingual; Angina Pectoris; Angioplasty, Balloon, Coronary

2009
Influence of sex on the out-of-hospital management of chest pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Aspirin; Chest Pain; Emergency Medical Services; Fem

2010
NICE guidance on the investigation of chest pain.
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:22

    Topics: Acute Coronary Syndrome; Angina Pectoris; Chest Pain; Evidence-Based Medicine; Humans; Nitroglycerin

2010
Part 9: Acute coronary syndromes: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.
    Circulation, 2010, Oct-19, Volume: 122, Issue:16 Suppl 2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Aspirin; Cardiopulm

2010
Part 9: Acute coronary syndromes: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.
    Circulation, 2010, Oct-19, Volume: 122, Issue:16 Suppl 2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Aspirin; Cardiopulm

2010
Part 9: Acute coronary syndromes: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.
    Circulation, 2010, Oct-19, Volume: 122, Issue:16 Suppl 2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Aspirin; Cardiopulm

2010
Part 9: Acute coronary syndromes: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.
    Circulation, 2010, Oct-19, Volume: 122, Issue:16 Suppl 2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Aspirin; Cardiopulm

2010
Prehospital evaluation and economic analysis of different coronary syndrome treatment strategies--PREDICT--rationale, development and implementation.
    BMC emergency medicine, 2011, Mar-29, Volume: 11

    Topics: Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Clinical Protocols; Cohort Stud

2011
The reconciliation of pressure and light: a clinical case of complementary use of fractional flow reserve and optical coherence tomography.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:8

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coro

2011
[Augmentation of vessel narrowing by nitroglycerine in a case with myocardial bridge].
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2011, Volume: 11, Issue:5

    Topics: Acute Coronary Syndrome; Coronary Angiography; Coronary Stenosis; Humans; Male; Middle Aged; Myocard

2011
Zolmitriptan induced acute coronary syndrome: a unique case.
    American journal of therapeutics, 2011, Volume: 18, Issue:5

    Topics: Acute Coronary Syndrome; Chest Pain; Electrocardiography; Humans; Male; Middle Aged; Migraine Disord

2011
[Angina pectoris and ST-elevation after chemotherapy with 5-fluorouracil].
    Der Internist, 2007, Volume: 48, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Carc

2007