nitroglycerin has been researched along with Achalasia in 13 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with vigorous achalasia demonstrated manometric response to administration of atropine sulfate and nitroglycerin." | 7.66 | Vigorous achalasia. Manometric response to atropine and nitroglycerin. ( Ona, FV; Polintan, LS, 1980) |
| "We conclude that in patients with achalasia (a) terbutaline sulfate, nitroglycerin, and aminophylline can significantly decrease LES pressure; (b) resting LES pressures vary over time; and (c) terbutaline sulfate and nitroglycerin significantly improve esophageal emptying in some subjects." | 6.66 | The effect of terbutaline sulfate, nitroglycerin, and aminophylline on lower esophageal sphincter pressure and radionuclide esophageal emptying in patients with achalasia. ( Castell, DO; Garcia, JE; Johnson, LF; Maydonovitch, C; Wong, RK, 1987) |
| "A patient with vigorous achalasia demonstrated manometric response to administration of atropine sulfate and nitroglycerin." | 3.66 | Vigorous achalasia. Manometric response to atropine and nitroglycerin. ( Ona, FV; Polintan, LS, 1980) |
| " As has similarly been reported for cholinergic agents in achalasia and in some cases of diffuse oesophageal spasm the oesophageal body responded in a hypersensitive fashion to subcutaneous and intravenous injections of pentagastrin." | 3.65 | Supersensitivity to pentagastrin in diffuse oesophageal spasm. ( Eckardt, V; Weigand, H, 1974) |
| "We conclude that in patients with achalasia (a) terbutaline sulfate, nitroglycerin, and aminophylline can significantly decrease LES pressure; (b) resting LES pressures vary over time; and (c) terbutaline sulfate and nitroglycerin significantly improve esophageal emptying in some subjects." | 2.66 | The effect of terbutaline sulfate, nitroglycerin, and aminophylline on lower esophageal sphincter pressure and radionuclide esophageal emptying in patients with achalasia. ( Castell, DO; Garcia, JE; Johnson, LF; Maydonovitch, C; Wong, RK, 1987) |
| "In 7 patients who had significant gastroesophageal reflux associated with spasm, the response to nitroglycerine was unpredictable." | 2.64 | Esophageal spasm: clinical and manometric response to nitroglycerine and long acting nitrites. ( Swamy, N, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ona, FV | 1 |
| Polintan, LS | 1 |
| Ferguson, SC | 1 |
| Hodges, K | 1 |
| Hersh, T | 1 |
| Jinich, H | 1 |
| Anselmino, M | 1 |
| Clark, GW | 1 |
| Hinder, RA | 1 |
| Efrati, Y | 1 |
| Horne, T | 1 |
| Livshitz, G | 1 |
| Broide, E | 1 |
| Klin, B | 1 |
| Vinograd, I | 1 |
| Hoogerwerf, WA | 1 |
| Pasricha, PJ | 1 |
| Swamy, N | 1 |
| Westbrook, JL | 1 |
| Krivchenia, DIu | 1 |
| Almashiĭ, GG | 1 |
| Iurchenko, NI | 1 |
| Dubrovin, AG | 1 |
| Brusilovskaia, GA | 1 |
| Palkina, IS | 1 |
| Wong, RK | 1 |
| Maydonovitch, C | 1 |
| Garcia, JE | 1 |
| Johnson, LF | 1 |
| Castell, DO | 1 |
| Pope, CE | 1 |
| Eckardt, V | 1 |
| Weigand, H | 1 |
| Winsor, R | 1 |
| Bleifer, K | 1 |
| Cole, S | 1 |
| Goldman, IR | 1 |
| Karpman, H | 1 |
| Oblath, R | 1 |
| Stone, S | 1 |
| Kramer, P | 1 |
3 reviews available for nitroglycerin and Achalasia
| Article | Year |
|---|---|
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E | 1993 |
Pharmacologic therapy in treating achalasia.
Topics: Botulinum Toxins, Type A; Calcium Channel Blockers; Esophageal Achalasia; Humans; Muscle, Smooth; Ne | 2001 |
Esophageal physiology.
Topics: Atropine; Barium Sulfate; Deglutition; Esophageal Achalasia; Esophageal Diseases; Esophagus; Gastrin | 1974 |
3 trials available for nitroglycerin and Achalasia
| Article | Year |
|---|---|
Esophageal spasm: clinical and manometric response to nitroglycerine and long acting nitrites.
Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Esophageal Achalasia; Esophagus; Femal | 1977 |
The effect of terbutaline sulfate, nitroglycerin, and aminophylline on lower esophageal sphincter pressure and radionuclide esophageal emptying in patients with achalasia.
Topics: Adult; Aminophylline; Esophageal Achalasia; Esophagogastric Junction; Esophagus; Female; Humans; Mal | 1987 |
A double-blind, double cross-over trial of prenylamine in angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Blood Pressure; Electrocardiography; Esophageal Achalasia; He | 1971 |
7 other studies available for nitroglycerin and Achalasia
| Article | Year |
|---|---|
Vigorous achalasia. Manometric response to atropine and nitroglycerin.
Topics: Atropine; Esophageal Achalasia; Esophagogastric Junction; Esophagus; Female; Humans; Manometry; Midd | 1980 |
Esophageal Manometry in Patients with Chest Pain and Normal Coronary Arteriogram.
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Diagnosis, Differential; Esophageal Achalasia; Esop | 1981 |
Radionuclide esophageal emptying and long-acting nitrates (Nitroderm) in childhood achalasia.
Topics: Child; Esophageal Achalasia; Esophagus; Female; Fundoplication; Humans; Nitroglycerin; Organotechnet | 1996 |
Oesophageal achalasia causing respiratory obstruction.
Topics: Acute Disease; Aged; Aged, 80 and over; Airway Obstruction; Esophageal Achalasia; Female; Humans; Ni | 1992 |
[Diagnosis and treatment of esophageal achalasia in children].
Topics: Adolescent; Child; Child, Preschool; Diagnosis, Differential; Dilatation; Esophageal Achalasia; Esop | 1990 |
Supersensitivity to pentagastrin in diffuse oesophageal spasm.
Topics: Adult; Atropine; Esophageal Achalasia; Esophagogastric Junction; Esophagus; Humans; Injections, Intr | 1974 |
Diffuse esophageal spasm.
Topics: Diagnosis, Differential; Diet Therapy; Esophageal Achalasia; Esophageal Diseases; Humans; Kymography | 1970 |