nitrogen-dioxide and Rhinitis--Allergic--Perennial

Mumbai, a mega city with a population of more than 12 million, is experiencing acute air pollution due to commercial activity, a boom in construction and vehicular traffic. This study was undertaken to investigate the link between air pollution and health impacts for Mumbai, and estimate the monetary burden of these impacts.. Cross-sectional data were subjected to logistic regression to analyse the link between air pollution and health impacts, and the cost of illness approach was used to measure the monetary burden of these impacts.. Data collected by the Environmental Pollution Research Centre at King Edward Memorial Hospital in Mumbai were analysed using logistic regression to investigate the link between air pollution and morbidity impacts. The monetary burden of morbidity was estimated through the cost of illness approach. For this purpose, information on treatment costs and foregone earnings due to illness was obtained through the household survey and interviews with medical practitioners.. Particulate matter (PM(10)) and nitrogen dioxide (NO(2)) emerged as the critical pollutants for a range of health impacts, including symptoms such as cough, breathlessness, wheezing and cold, and illnesses such as allergic rhinitis and chronic obstructive pulmonary disease (COPD). This study developed the concentration-response coefficients for these health impacts. The total monetary burden of these impacts, including personal burden, government expenditure and societal cost, is estimated at 4522.96 million Indian Rupees (INR) or US$ 113.08 million for a 50-μg/m(3) increase in PM(10), and INR 8723.59 million or US$ 218.10 million for a similar increase in NO(2).. The estimated monetary burden of health impacts associated with air pollution in Mumbai mainly comprises out-of-pocket expenses of city residents. These expenses form a sizable proportion of the annual income of individuals, particularly those belonging to poor households. These findings have implications for public health policy, particularly accessibility and affordability of health care for poor households in Mumbai. The study provides a rationale for strengthening the public health services in the city to make them more accessible to poor households, especially those living in the slums of Mumbai.

Topics: Air Pollution; Chronic Disease; Cross-Sectional Studies; Environmental Health; Health Care Costs; Health Policy; Humans; India; Logistic Models; Nitrogen Dioxide; Particulate Matter; Public Health; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Risk Factors

To investigate the effects of urban air quality change on health, we carried out a time-series analysis of daily general practitioner consultations for allergic rhinitis (AR) in Beijing, China. Non-parametric generalized additive model (GAM) was used to analyze the highly non-linear or non-monotonic exposure-response relationship between three air pollutants (namely PM₁₀, SO₂ and NO₂) and daily outpatient visits for AR, after controlling for long term trends, the 'day of the week' effect and confounding meteorological factors. The objective of this study was to assess the possible effects of air pollutants on outpatient visits caused by AR in Beijing during the period 2009-2010. Our work indicates that strong associations exist between daily concentration of the three air pollutants and the daily number of outpatients for AR.

Topics: Adult; Aged; Air Pollutants; Air Pollution; Ambulatory Care; China; Female; Humans; Inhalation Exposure; Male; Middle Aged; Nitrogen Dioxide; Particulate Matter; Rhinitis, Allergic, Perennial; Sulfur Dioxide; Young Adult

Children are vulnerable to air pollution, which is known to be related to the recent increasing trend of allergic disease.. To investigate the effects of air pollution on respiratory allergic diseases in school children.. A prospective survey of parental responses to International Study of Asthma and Allergies in Childhood questionnaires, together with allergy evaluation, was conducted in 1743 school children selected from metropolitan cities and industrial areas during a 2-year period. Individual exposure to air pollution was estimated by using a geometric information system with the 5-year mean concentration of air pollutants.. A total of 1,340 children (male:female ratio, 51.4:48.6) with a mean (SD) age of 6.84 (0.51) years were included in the analysis. Each child underwent allergy evaluation at the time of enrollment and at a 2-year follow-up. After 2 years, the 12-month prevalence of wheezing was significantly decreased, whereas the lifetime prevalence of allergic rhinitis showed a significant increase. Ozone exposure was significantly associated with the 12-month prevalence of wheeze (odds ratio per 5 ppb, 1.372; 95% confidence interval, 1.016-1.852). Ozone was also associated with allergic rhinitis in children who reside in industrial areas. In addition, significant positive associations between ozone and the rate of newly developed sensitization to outdoor allergen were found (P for trend = .007).. Exposure to ozone was associated with current wheeze and allergic rhinitis. An increased rate of newly developed sensitization to outdoor allergen by ozone may explain the association.

Topics: Air Pollutants; Asthma; Carbon Monoxide; Child; Environmental Exposure; Female; Health Surveys; Humans; Hypersensitivity; Immunoglobulin E; Incidence; Male; Nitrogen Dioxide; Ozone; Particulate Matter; Prevalence; Prospective Studies; Respiratory Sounds; Rhinitis, Allergic, Perennial; Skin Tests; Sulfur Dioxide

The objective of the study was to analyze the relationship between air pollutants and the prevalence of recent symptoms of asthma, allergic rhinitis, and atopic eczema in schoolchildren aged between 6 and 7 years.. The prevalence of recent (previous 12 months) symptoms of allergic diseases was obtained by means of the questionnaire of the International Study of Asthma and Allergies in Childhood (ISAAC), Spain, with the participation of 7 centers (Asturias, Barcelona, Bilbao, Cartagena, La Coruña, Madrid, and Valencia) and 20 455 schoolchildren aged between 6 and 7 years, from 2002 to 2003. The pollutant detection systems of the aforementioned centers provided the mean annual concentrations of sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and total suspended particulate matter.. The annual average concentration of SO2 showed a significant association with a higher prevalence of recent severe asthma (adjusted odds ratio [aOR] between level-1 and level-3 pollution, 1.32; 95% confidence interval [CI], 1.01-1.73), rhinitis (aOR, 1.56; 95% CI, 1.39-1.75), and rhinoconjunctivitis (aOR, 1.70; 95% CI, 1.45-2.00). The annual average concentration of CO was associated with a higher prevalence of rhinitis (aOR, 1.65; 95% CI, 1.34-2.04), rhinoconjunctivitis (aOR, 1.76; 95% CI, 1.31-2.37), and eczema (aOR, 1.55; 95% CI, 1.17-2.04). The annual average concentration for NO2 and total suspended particulate matter showed inverse associations with the prevalence of nocturnal dry cough.. Findings suggest that air pollutants such as SO2 and CO increase the risk of recent symptoms of asthma and allergic rhinitis in schoolchildren aged between 6 and 7 years in Spain.

Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Cough; Dermatitis, Atopic; Female; Humans; Male; Meteorological Concepts; Nitrogen Dioxide; Particulate Matter; Prevalence; Respiratory Sounds; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Spain; Sulfur Dioxide; Urban Population

This study was conducted in order to determine the relationship between air pollution and the varying prevalence of allergic diseases in the city of Taichung and the rural town of Chu-Shan. We used questionnaires to screen children aged from 7 to 15 years in Taichung and Chu-Shan and compared the results from these 2 areas with the factors related to air pollution. The study included 11,580 children in Taichung and 2621 children in Chu-Shan. In Taichung, the prevalence of asthma was 7.0%, of allergic rhinitis 27.6% and of atopic dermatitis 3.4%. In Chu-Shan, the prevalence of asthma was 5.6%, of allergic rhinitis 21.8% and of atopic dermatitis 3.3%. We also collected data on the concentration of air pollutants in the 2 areas over a 1-year period from January to December 2001 and compared the average annual concentrations of various pollutants. Compared with Chu-Shan, Taichung had higher air concentrations of nitric oxide (NO; 11.47 +/- 4.75 vs 5.07 +/- 2.81 ppb), carbon monoxide (CO; 0.78 +/- 0.19 vs 0.59 +/- 0.12 ppm), nitrogen dioxide (NO(2); 24.99 +/- 6.8 vs 21.45 +/- 7.87 ppb) and sulfur dioxide (SO(2); 2.58 +/- 1.0 vs 2.44 +/- 0.88 ppb). Student's t test results showed that CO and NO were related significantly to the prevalence of allergic disease (p<0.005). The prevalence of both asthma and allergic rhinitis is higher in Taichung than in Chu-Shan, a finding that could be related to higher levels of some air pollutants in the urban location.

Topics: Adolescent; Air Pollution; Asthma; Carbon Monoxide; Child; Dermatitis, Atopic; Female; Humans; Hypersensitivity; Male; Nitric Oxide; Nitrogen Dioxide; Prevalence; Rhinitis, Allergic, Perennial; Risk Factors; Rural Health; Sulfur Dioxide; Taiwan; Urban Health

Topics: Air Pollutants; Asthma; Humans; Nitrogen Dioxide; Ozone; Prevalence; Rhinitis, Allergic, Perennial; Ultraviolet Rays; Vehicle Emissions

Environmental factors are likely to be involved in explaining the wide geographical variation in asthma and atopic diseases that has been documented in many recent epidemiological studies.. To evaluate to what extent climate and outdoor NO2 pollution can explain the geographical variation in the prevalence of asthma and allergic rhinitis, and to estimate the relative risk for exposure to different levels of these two factors.. The impact of climate and long-term exposure to nitrogen dioxide (NO2) pollution on asthma and allergic rhinitis was assessed in a cross-sectional study, carried out during 1998 to 2000 on young adults aged 20 to 44 years (n = 18 873), living in 13 areas from two different Italian climatic regions (subcontinental and Mediterranean).. Mediterranean areas had a significantly higher prevalence of asthma-like symptoms (P < 0.001), higher annual mean temperature (16.2 degrees C vs. 12.9 degrees C), lower temperature range (16.0 C degrees vs. 22.1 degrees C) and lower NO2 levels (31.46 microg/m3 vs. 57.99 microg/m3) than subcontinental ones. Mediterranean climate was associated with an increased risk of wheeze (OR = 1.23; 95% CI 1.13 to 1.35), tightness in the chest (OR = 1.21; 95% CI 1.11 to 1.33), shortness of breath (OR = 1.21; 95% CI 1.08 to 1.36) and asthma attacks (OR = 1.19; 95% CI 1.07 to 1.31). After adjusting for climate, an increase of 18.3 microg/m3 in NO2 levels moderately increased the risk of asthma attacks (OR = 1.13; 95% CI 0.98 to 1.32), tightness in the chest (OR = 1.11; 95% CI 0.98 to 1.26) and wheeze (OR = 1.11; 95% CI 0.96 to 1.28). When the levels of outdoor NO2 exposure rose, the prevalence of allergic rhinitis increased significantly in the Mediterranean region (OR = 1.38; 95% CI 1.12 to 1.69), but not in the subcontinental one (OR = 1.03; 95% CI 0.83 to 1.28).. Our results show that the prevalence of asthma increases when annual mean temperature increases and temperature range decreases. Furthermore, climate interacts with NO2 outdoor exposure, increasing the risk for allergic rhinitis in people exposed to high stable temperatures. A long-term role for the effect of traffic pollution on asthma is also suggested.

Topics: Adult; Asthma; Climate; Cross-Sectional Studies; Humans; Italy; Multivariate Analysis; Nitrogen Dioxide; Prevalence; Rhinitis, Allergic, Perennial; Temperature; Ultraviolet Rays; Vehicle Emissions