nitrogen-dioxide and Periodontal-Diseases

We aimed to characterize the association between air pollutants exposure and periodontal diseases outpatient visits and to explore the interactions between ambient air pollutants and meteorological factors. The outpatient visits data of several large stomatological and general hospitals in Hefei during 2015-2020 were collected to explore the relationship between daily air pollutants exposure and periodontal diseases by combining Poisson's generalized linear model (GLMs) and distributed lag nonlinear model (DLNMs). Subgroup analysis was performed to identify the vulnerability of different populations to air pollutants exposure. The interaction between air pollutants and meteorological factors was verified in both multiplicative and additive interaction models. An interquartile range (IQR) increased in nitrogen dioxide (NO

Topics: Aged; Air Pollutants; Air Pollution; China; Environmental Exposure; Gingivitis; Humans; Meteorological Concepts; Nitrogen Dioxide; Particulate Matter; Periodontal Diseases; Periodontitis

Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; DNA; Fatty Acids; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrogen Dioxide; Periodontal Diseases; Peroxisome Proliferator-Activated Receptors; Phenols; Prevotella intermedia; RNA, Messenger; Water

Limited studies have explored the relationship between air pollution and rheumatoid arthritis (RA), with the results being somewhat inconsistent.. This was a retrospective cohort study that included 322,301 subjects aged 30-50 years, selected from the National Health Insurance Research Database in Taiwan, were followed from 2001 to 2010. We used a time-dependent extended Cox model and incorporated time-dependent variables to estimate the associations between the annual mean concentrations of air pollutants with RA, including carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O3), particles with an aerodynamic diameter less than 10 μm (PM10), and sulfur dioxide (SO2), and reported the hazard ratio (HR) and 95% confidence interval (CI).. Newly diagnosed RA was positively associated with a 100-ppb increase in CO (adjusted HR = 1.17 [95% CI = 1.16, 1.18]), a 10-ppb increase in NO2 (1.54 [1.45, 1.64]), a 10-ppb increase in O3 (1.37 [1.33, 1.41]), and a 1 ppb in SO2 (1.02 [1.00, 1.04]). There was no association between a 10-μg/m increase in PM10 and RA (1.02 [0.99, 1.05]).. Our finding suggests that O3 and traffic-related air pollutants (CO and NO2) may be positively associated with incident RA. This is an important finding given that many individuals are exposed to similar levels of O3 and NO2 globally.

Topics: Adult; Air Pollution; Arthritis, Rheumatoid; Carbon Monoxide; Cohort Studies; Comorbidity; Environmental Exposure; Humans; Incidence; Infections; Middle Aged; Nitrogen Dioxide; Ozone; Particle Size; Particulate Matter; Periodontal Diseases; Proportional Hazards Models; Retrospective Studies; Social Class; Sulfur Dioxide; Taiwan