nitrogen-dioxide and Leishmaniasis--Visceral

nitrogen-dioxide has been researched along with Leishmaniasis--Visceral* in 2 studies

Other Studies

2 other study(ies) available for nitrogen-dioxide and Leishmaniasis--Visceral

Article	Year
PD-1 regulates leishmanicidal activity and IL-17 in dogs with leishmaniasis. Veterinary immunology and immunopathology, 2020, Volume: 219 Leishmaniasis is an immunosuppressive disease caused by protozoa of the genus Leishmania, for which dogs are the domestic reservoir. The programmed cell death-1 molecule (PD-1) is highly expressed in leukocyte cells of dogs with leishmaniasis, and it promotes T lymphocyte exhaustion and suppression of cytokine secretion. Because PD-1 has a suppressive function regarding cell immunity, we evaluated the effect of PD-1 blocking antibodies on NO, ROS and interleukin 17 (IL-17) production and on parasite load in spleen leukocyte cultures from dogs with leishmaniasis. In vitro, PD-1 blocking promoted increased levels of intracellular NO and NO Topics: Animals; Antibodies, Monoclonal; Cell Culture Techniques; Culture Media; Dog Diseases; Dogs; Female; Gene Expression Regulation; Interleukin-17; Leishmania infantum; Leishmaniasis, Visceral; Leukocytes; Male; Nitric Oxide; Nitrogen Dioxide; Parasite Load; Programmed Cell Death 1 Receptor; Reactive Oxygen Species; Spleen	2020
rIL-2-stimulated splenocytes reactivate the NO2-producing ability of macrophages infected by Leishmania donovani. Immunopharmacology and immunotoxicology, 2000, Volume: 22, Issue:3 Infection with L. donovani down-regulates immunity and parasite clearance by macrophages. Treatment with IL-2-stimulated-splenocytes activate parasiticidal action in vitro in peritoneal macrophages of C57BL/6 (Lsh(s)) mice and also was effective in stimulating infected macrophages to produce NO2-. Topics: Animals; Cricetinae; Female; Hydrogen Peroxide; In Vitro Techniques; Interleukin-2; Leishmania donovani; Leishmaniasis, Visceral; Macrophage Activation; Macrophages, Peritoneal; Mesocricetus; Mice; Mice, Inbred C57BL; Nitrogen Dioxide; Recombinant Proteins; Spleen; Superoxides	2000

Article

Year

PD-1 regulates leishmanicidal activity and IL-17 in dogs with leishmaniasis.

Veterinary immunology and immunopathology, 2020, Volume: 219

Leishmaniasis is an immunosuppressive disease caused by protozoa of the genus Leishmania, for which dogs are the domestic reservoir. The programmed cell death-1 molecule (PD-1) is highly expressed in leukocyte cells of dogs with leishmaniasis, and it promotes T lymphocyte exhaustion and suppression of cytokine secretion. Because PD-1 has a suppressive function regarding cell immunity, we evaluated the effect of PD-1 blocking antibodies on NO, ROS and interleukin 17 (IL-17) production and on parasite load in spleen leukocyte cultures from dogs with leishmaniasis. In vitro, PD-1 blocking promoted increased levels of intracellular NO and NO

Topics: Animals; Antibodies, Monoclonal; Cell Culture Techniques; Culture Media; Dog Diseases; Dogs; Female; Gene Expression Regulation; Interleukin-17; Leishmania infantum; Leishmaniasis, Visceral; Leukocytes; Male; Nitric Oxide; Nitrogen Dioxide; Parasite Load; Programmed Cell Death 1 Receptor; Reactive Oxygen Species; Spleen

2020

rIL-2-stimulated splenocytes reactivate the NO2-producing ability of macrophages infected by Leishmania donovani.

Immunopharmacology and immunotoxicology, 2000, Volume: 22, Issue:3

Infection with L. donovani down-regulates immunity and parasite clearance by macrophages. Treatment with IL-2-stimulated-splenocytes activate parasiticidal action in vitro in peritoneal macrophages of C57BL/6 (Lsh(s)) mice and also was effective in stimulating infected macrophages to produce NO2-.

Topics: Animals; Cricetinae; Female; Hydrogen Peroxide; In Vitro Techniques; Interleukin-2; Leishmania donovani; Leishmaniasis, Visceral; Macrophage Activation; Macrophages, Peritoneal; Mesocricetus; Mice; Mice, Inbred C57BL; Nitrogen Dioxide; Recombinant Proteins; Spleen; Superoxides

2000