nitrogen-dioxide and Eczema

Immunoglobulin E (IgE)-mediated allergic diseases, including eczema, atopic dermatitis (AD), and allergic rhinitis (AR), have increased prevalence in recent decades. Recent studies have proved that environmental pollution might have correlations with IgE-mediated allergic diseases, but existing research findings were controversial. Thus, we performed a comprehensive meta-analysis from published observational studies to evaluate the risk of long-term and short-term exposure to air pollutants on eczema, AD, and AR in the population (per 10-μg/m

Topics: Air Pollutants; Air Pollution; Eczema; Environmental Exposure; Environmental Pollutants; Humans; Immunoglobulin E; Nitrogen Dioxide; Particulate Matter; Rhinitis, Allergic

Ambient nitrogen dioxide (NO. To measure the effect of short-term exposure of NO. Data of daily temperature, air pollutants, and outpatient visits from 2013 to 2018 were collected in a row. The generalized additive model (GAM) and Poisson distribution were used to assess the association between short-term exposure of NO. The daily outpatient visits of eczema increased from 75.26 to 190.85 from 2013 to 2018 (P < 0.001). The combined influence of NO. Exposure to NO

Topics: Air Pollutants; Air Pollution; Child; China; Eczema; Hospitals; Humans; Nitrogen Dioxide; Outpatients; Particulate Matter

There is growing evidence that air pollution may contribute to the development of childhood asthma and other allergic diseases. In this follow-up of the Toronto Child Health Evaluation Questionnaire (T-CHEQ) study, we examined associations between early life exposures to air pollution and incidence of asthma, allergic rhinitis and eczema from birth through adolescence.. Hazard ratios of 1.17 (95% CI 1.05-1.31) for asthma and 1.07 (95% CI 0.99-1.15) for eczema were observed for total oxidants (O. Exposures to oxidant air pollutants (O

Topics: Adolescent; Air Pollutants; Air Pollution; Asthma; Child; Eczema; Environmental Exposure; Humans; Incidence; Infant, Newborn; Nitrogen Dioxide; Particulate Matter; Rhinitis, Allergic

Evidence linking prenatal exposure to outdoor air pollution with eczema in early childhood is scare, and the role of components of air pollution and exposure timing remains unclear.. We investigated the association between exposure to air pollution during preconceptional and perinatal period and the risk of eczema in preschool children.. We conducted a prospective cohort study of 2598 children aged 3-6 years in Changsha, China. The prevalence of eczema was assessed by a standardized health questionnaire administered by the parents. Individual exposures to nitrogen dioxide (NO. Life-time prevalence of eczema in preschool children in Changsha was 28.6%. Childhood eczema was associated with traffic-related air pollutant NO. Our findings support the hypothesis that early childhood eczema is associated with exposure to traffic-related air pollutant during both preconceptional and perinatal period, especially at a high level of exposure.

Topics: Air Pollutants; Air Pollution; Child; Child, Preschool; China; Eczema; Environmental Monitoring; Female; Humans; Male; Maternal Exposure; Nitrogen Dioxide; Parents; Particulate Matter; Paternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Risk Factors; Sulfur Dioxide; Surveys and Questionnaires

Associations between traffic-related air pollution and incident childhood asthma can be strengthened by analysis of gene-environment interactions, but studies have typically been limited by lack of study power. We combined data from six birth cohorts on: asthma, eczema and allergic rhinitis to 7/8 years, and candidate genes. Individual-level assessment of traffic-related air pollution exposure was estimated using land use regression or dispersion modeling. A total of 11,760 children were included in the Traffic, Asthma and Genetics (TAG) Study; 6.3 % reported physician-diagnosed asthma at school-age, 16.0 % had asthma at anytime during childhood, 14.1 % had allergic rhinitis at school-age, 10.0 % had eczema at school-age and 33.1 % were sensitized to any allergen. For GSTP1 rs1138272, the prevalence of heterozygosity was 16 % (range amongst individual cohorts, 11-17 %) and homozygosity for the minor allele was 1 % (0-2 %). For GSTP1 rs1695, the prevalence of heterozygosity was 45 % (40-48 %) and homozygosity for the minor allele, 12 % (10-12 %). For TNF rs1800629, the prevalence of heterozygosity was 29 % (25-32 %) and homozygosity for the minor allele, 3 % (1-3 %). TAG comprises a rich database, the largest of its kind, for investigating the effect of genotype on the association between air pollution and childhood allergic disease.

Topics: Air Pollution; Asthma; Child; Eczema; Environmental Exposure; Female; Gene-Environment Interaction; Genotype; Glutathione S-Transferase pi; Humans; Incidence; Inflammation; Male; Nitrogen Dioxide; Oxidative Stress; Polymorphism, Single Nucleotide; Rhinitis; Tumor Necrosis Factor-alpha; Vehicle Emissions

Several studies reported inconsistent associations between using gas for cooking and respiratory symptoms or lung function in children. Kitchen ventilation characteristics may modify the relationship between gas cooking and respiratory health. The aim of this study was to investigate the effect of kitchen ventilation (while cooking) on the relationship between gas cooking, combustion product dispersal, and respiratory and allergic outcomes in children.. Data on respiratory and allergic symptoms and diagnoses were collected by yearly questionnaires in a population of over 3000 children participating in a birth cohort study on development of allergy and asthma. At 4 years of age, a sub-sample of 647 children provided blood samples for antibody testing. Data on gas cooking and kitchen ventilation were collected when the children were 5 years old. Based on these data a model was constructed to determine the chance of accumulation of combustion products (CACP) in the kitchen.. No relationship was found between gas cooking and any of the respiratory or allergy outcomes except nasal symptoms. The overall results did not change when the 'CACP' was used as exposure variable instead, while the association for nasal symptoms decreased to borderline significance.. Our results suggest that gas cooking per se is associated with nasal symptoms in young children and not with the other respiratory symptoms that were investigated. Taking kitchen ventilation characteristics into account did not lead to different conclusions in this population where, according to the classification system, the majority of households using gas for cooking have insufficient kitchen ventilation.

Topics: Air Pollution, Indoor; Asthma; Child, Preschool; Cohort Studies; Comorbidity; Cooking; Eczema; Fossil Fuels; Humans; Models, Statistical; Netherlands; Nitrogen Dioxide; Odds Ratio; Paranasal Sinuses; Prevalence; Respiratory Hypersensitivity; Respiratory Sounds; Surveys and Questionnaires; Ventilation

Topics: Animals; Antigen-Antibody Reactions; Benzene Derivatives; Chromium Isotopes; Cytotoxicity Tests, Immunologic; Dermatitis, Contact; Eczema; Guinea Pigs; Haptens; Immunologic Techniques; Lymphocytes; Macrophages; Nitrogen Dioxide; Skin Tests; Time Factors