nitrogen-dioxide and Diabetes--Gestational

Numerous studies have evaluated the association between air pollution and gestational diabetes mellitus (GDM), but the findings were inconsistent. This meta-analysis aimed to provide higher grade evidence on the association of air pollution with GDM based on previous studies. PubMed, Web of science, China National Knowledge Infrastructure (CNKI), and Wanfang Data Knowledge Service Platform (Wanfang) were searched comprehensively up to September 2021. Totally, 20 eligible cohort studies were finally included, for which the pooled RR and 95% CIs were estimated. Stratified analyses by study regions and units of pollutant increase were conducted for further investigation. Sensitivity analyses were also performed to assess the robustness. The finding showed that PM

Topics: Air Pollutants; Air Pollution; Cohort Studies; Diabetes, Gestational; Female; Humans; Maternal Exposure; Nitrogen Dioxide; Particulate Matter; Pregnancy

The global prevalence of gestational diabetes mellitus (GDM) is increasing annually, and previous research reports on the relationship between exposure to air pollutants and GDM are not completely consistent. We investigated the association between air pollutant exposure and GDM in pregnant women in a retrospective cohort study in Guangzhou. We found that in the first trimester, exposure to PM

Topics: Air Pollutants; Air Pollution; Diabetes, Gestational; Female; Humans; Maternal Exposure; Nitrogen Dioxide; Particulate Matter; Pregnancy; Pregnant Women; Retrospective Studies

Neonatal mortality and morbidity are often caused by preterm birth and lower birth weight. Gestational diabetes mellitus (GDM) and gestational hypertension (GH) are the most prevalent maternal medical complications during pregnancy. However, evidence on effects of air pollution on adverse birth outcomes and pregnancy complications is mixed. Singleton live births conceived between January 1st, 2000, and December 31st, 2015, and reached at least 27 weeks of pregnancy in Kansas were included in the study. Trimester-specific and total pregnancy exposures to nitrogen dioxide (NO

Topics: Air Pollutants; Air Pollution; Birth Weight; Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Kansas; Maternal Exposure; Nitrogen Dioxide; Particulate Matter; Pregnancy; Premature Birth

Epidemiological findings are inconsistent regarding the associations between air pollution exposure during pregnancy and gestational diabetes mellitus (GDM). Several limitations exist in previous studies, including potential outcome and exposure misclassification, unassessed confounding, and lack of simultaneous consideration of air pollution mixtures and particulate matter (PM) constituents.. To assess the association between GDM and maternal residential exposure to air pollution, and the joint effect of the mixture of air pollutants and PM constituents.. This study found that exposure to a mixture of ambient PM

Topics: Air Pollutants; Air Pollution; California; Diabetes, Gestational; Electronic Health Records; Environmental Exposure; Female; Humans; Nitrogen Dioxide; Particulate Matter; Pregnancy

Exposures to multiple air pollutants during pregnancy have been associated with the risk of gestational diabetes mellitus (GDM). However, their combined effects are unclear. We aimed to evaluate the combined associations of five air pollutants from pre-pregnancy to the 2nd trimester with GDM. This study included 20,113 participants from the Born in Guangzhou Cohort Study (BIGCS). The inverse distance-weighted models were used to estimate individual air pollutant exposure, namely ozone (O

Topics: Air Pollutants; Air Pollution; Cohort Studies; Diabetes, Gestational; Female; Humans; Nitrogen Dioxide; Particulate Matter; Pregnancy; Prospective Studies

Gestational hypertension (GH), preeclampsia (PE), and gestational diabetes mellitus (GDM) are common pregnancy complications and can result in maternal and prenatal morbidity and mortality. Air pollution exposure could adversely impact pregnancy complications; however, evidence remains limited in China, where ambient air pollution is relatively severe.. This study aims to examine the associations of GH, PE, and GDM with exposure to six air pollutants (PM. Leveraging a multicenter birth cohort study among pregnant women in 24 hospitals from 15 provinces in China, we obtained data for maternal characteristics and pregnancy outcomes. We generated ambient concentrations of the six air pollutants using a combination of chemical transport model simulations with monitoring data. We used multivariable logistic regression models to estimate the effects on pregnancy complications from exposure to six air pollutants in each trimester and the entire pregnancy.. Among the total 3754 pregnant women in this study, the prevalences of GH, GDM, and PE were 2.6 %, 11.2 %, and 0.7 %, respectively. GH risk increased 11.9 % (95 % CI, -8.5 %, 36.8 %) and 13.8 % (1.4 %, 27.8 %) per 10 μg/m. Ambient particulate matter pollution adversely affects GH, GDM, and PE among Chinese pregnant women. Since most regions of China still suffer from hazardous levels of air pollution, our findings indicate importance of better protecting pregnant women from the risk of air pollution.

Topics: Air Pollutants; Air Pollution; China; Cohort Studies; Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Maternal Exposure; Nitrogen Dioxide; Particulate Matter; Pregnancy; Pregnancy Complications

There is some evidence about the short-term effects of air pollutants on adverse pregnancy outcomes. The aim of this study was to determine the association between air pollutants and spontaneous abortion, stillbirth, gestational hypertension, preeclampsia, gestational diabetes and macrosomia in Ahvaz, which is one of the most polluted cities in the Middle East.. Data on adverse pregnancy outcomes and air pollutants including ozone (O. The results showed that the SO. The results of this study suggest that some air pollutants are associated with spontaneous abortion, preeclampsia, gestational diabetes and macrosomia. This study further emphasizes the need to control ambient air pollution.

Topics: Air Pollutants; Air Pollution; Carbon Monoxide; Diabetes, Gestational; Female; Fetal Macrosomia; Humans; Hypertension, Pregnancy-Induced; Iran; Maternal Exposure; Models, Theoretical; Nitric Oxide; Nitrogen Dioxide; Ozone; Particulate Matter; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Sulfur Dioxide

There is mixed evidence implicating prenatal exposure to particulate matter <2.5 μm in aerodynamic diameter (PM. We conducted a retrospective cohort study of singleton live births in Harris County, Texas from 2008 to 2013. With data from the Texas Commission on Environmental Quality (TCEQ), we spatially interpolated maternal exposures to total and speciated PM. An interquartile range (IQR) increase in total PM. Exposures to PM

Topics: Air Pollutants; Air Pollution; Child; Diabetes, Gestational; Female; Humans; Nitrogen Dioxide; Particulate Matter; Pregnancy; Retrospective Studies; Texas

Ambient air pollution and maternal diabetes may affect common biological pathways underlying adverse neurodevelopmental effects. However, joint effects of maternal diabetes and air pollution on autism spectrum disorder (ASD) have not been studied.. We evaluated whether prenatal and early-life air pollution exposure interacts with maternal diabetes status to affect ASD risk.. This retrospective cohort study included 246,420 singleton children born in Kaiser Permanente Southern California hospitals in 1999-2009. Children were followed from birth until age 5, during which 2471 ASD cases were diagnosed. Ozone (O. There were associations of ASD with preconception, first and third trimesters, and first year of life PM. GDM onset early in pregnancy may increase children's susceptibility to prenatal O

Topics: Adult; Air Pollutants; Autism Spectrum Disorder; California; Child, Preschool; Cohort Studies; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Infant; Infant, Newborn; Male; Maternal Exposure; Nitrogen Dioxide; Ozone; Particulate Matter; Pregnancy; Pregnancy Trimesters; Proportional Hazards Models; Retrospective Studies

Emerging evidence suggests a potential association between ambient air pollution and risk of gestational diabetes mellitus (GDM), but results have been inconsistent. Accordingly, we assessed the associations between ambient fine particulate matter (PM. Using linked data from birth certificates, hospital discharge diagnoses, and air pollution estimates informed by the New York City Community Air Survey, we fit conditional logistic regression models to evaluate the association between residential levels of PM. GDM was identified in 17,065 women, yielding a risk of GDM in the study sample of 67 per 1000 deliveries. In single pollutant models, 1st and 2nd trimester PM. In this large cohort of singleton births in New York City, NO

Topics: Adult; Air Pollutants; Air Pollution; Diabetes, Gestational; Female; Humans; Maternal Exposure; New York City; Nitrogen Dioxide; Particulate Matter; Pregnancy

Road traffic is a main source of air pollution and noise. Both exposures have been associated with type 2 diabetes, but associations with gestational diabetes mellitus (GDM) have been studied less.. We aimed to examine single and joint associations of exposure to air pollution and road traffic noise on GDM in a prospective cohort.. We identified GDM cases from self-reports and hospital records, using two different criteria, among 72,745 singleton pregnancies (1997-2002) from the Danish National Birth Cohort. We modeled nitrogen dioxide (NO. According to the two diagnostic criteria: the Danish clinical guidelines, which was our main outcome, and the WHO standard during recruitment period, a total of 565 and 210 women, respectively, had GDM. For both exposures no risk was evident for the common Danish criterion of GDM. A 10-μg/m. No risk was evident for the common Danish criterion of GDM. NO

Topics: Adult; Air Pollutants; Automobiles; Cohort Studies; Diabetes, Gestational; Environmental Exposure; Female; Humans; Maternal Exposure; Nitrogen Dioxide; Noise; Odds Ratio; Pregnancy; Prospective Studies; Risk; Young Adult