nitrogen-dioxide and Cerebrovascular-Disorders

Ambient air pollution is the environmental factor with the most significant impact on human health. Several epidemiological studies provide evidence for an association between ambient air pollution and human health. However, the recent economic literature has challenged the identification strategy used in these studies. This paper contributes to the ongoing discussion by investigating the association between ambient air pollution and morbidity using hospital admission data from Switzerland. Our identification strategy rests on the construction of geographically explicit pollution measures derived from a dispersion model that replicates atmospheric conditions and accounts for several emission sources. The reduced form estimates account for location and time fixed effects and show that ambient air pollution has a substantial impact on hospital admissions. In particular, we show that [Formula: see text] and [Formula: see text] are positively associated with admission rates for coronary artery and cerebrovascular diseases while we find no similar correlation for PM10 and [Formula: see text]. Our robustness checks support these findings and suggest that dispersion models can help in reducing the measurement error inherent to pollution exposure measures based on station-level pollution data. Therefore, our results may contribute to a more accurate evaluation of future environmental policies aiming at a reduction of ambient air pollution exposure.

Topics: Air Pollutants; Air Pollution; Animals; Cerebrovascular Disorders; Coronary Artery Disease; Environmental Monitoring; Hospitalization; Humans; Nitrogen Dioxide; Ozone; Particulate Matter; Sulfur Dioxide; Switzerland

In recent years, ambient air has been severely contaminated by particulate matters (PMs) and some gas pollutants (nitrogen dioxide (NO

Topics: Air Pollutants; Air Pollution; Cerebrovascular Disorders; China; Environmental Exposure; Humans; Lung Neoplasms; Meteorological Concepts; Mortality; Myocardial Ischemia; Nitrogen Dioxide; Particulate Matter; Public Health; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Infections; Seasons; Sulfur Dioxide

To study the association of air pollution with health service demand of the elderly and middle-age patients with cardiovascular and cerebrovascular diseases, and to provide a scientific basis for development of environmental protection policy and health service policy of the Chinese government.. This study included survey data on self-evaluated health, outpatient service demand and inpatient service demand of the patients with hypertension, heart disease and stroke in 62 cities of 17 provinces from China Health and Retirement Longitudinal Study (CHARLS) in 2011 and 2013, and combined it with the data on the annual concentrations of inhalable particulate matter (PM(10)), sulfur dioxide(SO(2)) and nitrogen dioxide (NO(2)) of those provinces and cities. Conditional Logistic regression was carried out to assess the possible effects of air pollutants on self-evaluated health and health service utilization.. The results showed that turning points existed in the effects of concentrations of NO(2) and SO(2) on the health service demand of the patients with hypertension, heart disease and stroke. The inpatient service demand of the hypertension patients increased with NO(2) concentration when it was lower than 35.1 μg/m(3) and decreased with NO(2) concentration for higher value. Self-evaluated health of the patients with heart disease and stroke decreased with SO(2) concentration when it was lower than 63.8 μg/m(3) and increased with SO(2) concentration for higher value. In addition, no evidence was found for the association between PM(10) and health service demand.. Air pollution may have effects on health service demand of the patients with hypertension,cardiovascular and cerebrovascular diseases, and different air pollutants at high or low concentration may have different health effects.

Topics: Aged; Air Pollutants; Air Pollution; Cerebrovascular Disorders; China; Cities; Health Services; Health Services Needs and Demand; Humans; Hypertension; Longitudinal Studies; Middle Aged; Nitrogen Dioxide; Particulate Matter; Stroke; Sulfur Dioxide

Little evidence is available about the association between temperature and cerebrovascular mortality in China. This study aims to examine the effects of ambient temperature on cerebrovascular mortality in different climatic zones in China.. We obtained daily data on weather conditions, air pollution and cerebrovascular deaths from five cities (Beijing, Tianjin, Shanghai, Wuhan, and Guangzhou) in China during 2004-2008. We examined city-specific associations between ambient temperature and the cerebrovascular mortality, while adjusting for season, long-term trends, day of the week, relative humidity and air pollution. We examined cold effects using a 1°C decrease in temperature below a city-specific threshold, and hot effects using a 1°C increase in temperature above a city-specific threshold. We used a meta-analysis to summarize the cold and hot effects across the five cities.. Beijing and Tianjin (with low mean temperature) had lower thresholds than Shanghai, Wuhan and Guangzhou (with high mean temperature). In Beijing, Tianjin, Wuhan and Guangzhou cold effects were delayed, while in Shanghai there was no or short induction. Hot effects were acute in all five cities. The cold effects lasted longer than hot effects. The hot effects were followed by mortality displacement. The pooled relative risk associated with a 1°C decrease in temperature below thresholds (cold effect) was 1.037 (95% confidence interval (CI): 1.020, 1.053). The pooled relative risk associated with a 1°C increase in temperature above thresholds (hot effect) was 1.014 (95% CI: 0.979, 1.050).. Cold temperatures are significantly associated with cerebrovascular mortality in China, while hot effect is not significant. People in colder climate cities were sensitive to hot temperatures, while people in warmer climate cities were vulnerable to cold temperature.

Topics: Air Pollutants; Cerebrovascular Disorders; China; Climate; Humans; Humidity; Nitrogen Dioxide; Particulate Matter; Risk; Temperature

Exposure to air pollutants has been associated with increased hospital admissions (HAs) for respiratory and cardiovascular diseases. This work describes a short-term epidemiological study in Brindisi, a highly industrialized town in Southern Italy. The effects of daily exposure to PM10 and NO2 on daily HAs for cardiac, respiratory, and cerebrovascular diseases were investigated by means of a case-crossover design in the period 2001-2007. Results showed positive associations between PM10 and HAs for cardiac and respiratory diseases and between NO2 and HAs for all the categories of diseases considered, particularly among females. Although not statistically significant, increased risk was observed for wind blowing from the port and the industrial area. Findings confirm the health risks associated with ambient air pollution exposure, even though NO2 and PM10 concentrations were below the legal limits. This may be due to the complex scenario of emissions in the area, which should be better investigated.

Topics: Adult; Aged; Air Pollutants; Cardiovascular Diseases; Cerebrovascular Disorders; Cities; Environmental Exposure; Environmental Monitoring; Female; Humans; Italy; Male; Middle Aged; Nitrogen Dioxide; Particle Size; Particulate Matter; Respiratory Tract Diseases; Risk Factors; Seasons; Time Factors; Wind

Panel studies show a consistent association between increase in the cardiovascular hospitalizations with air pollutants in economically developed regions, but little evidence in less developed inland areas. In this study, a time-series analysis was used to examine the specific effects of major air pollutants [particulate matter less than 10 microns in diameter (PM(10)), sulfur dioxide (SO(2)), and nitrogen dioxides (NO(2))] on daily hospital admissions for cardio-cerebrovascular diseases in Lanzhou, a heavily polluted city in China. We examined the effects of air pollutants for stratified groups by age and gender, and conducted the modifying effect of seasons on air pollutants to test the possible interaction. The significant associations were found between PM(10), SO(2) and NO(2) and cardiac disease admissions, SO(2) and NO(2) were found to be associated with the cerebrovascular disease admissions. The elderly was associated more strongly with gaseous pollutants than younger. The modifying effect of seasons on air pollutants also existed. The significant effect of gaseous pollutants (SO(2) and NO(2)) was found on daily hospital admissions even after adjustment for other pollutants except for SO(2) on cardiac diseases. In a word, this study provides the evidence for the detrimental short-term health effects of urban gaseous pollutants on cardio-cerebrovascular diseases in Lanzhou.

Topics: Air Pollutants; Cardiovascular Diseases; Cerebrovascular Disorders; China; Cities; Environmental Exposure; Gases; Hospitalization; Humans; Nitrogen Dioxide; Particulate Matter; Sulfur Dioxide

The relationship between ambient air pollution exposure and mortality of cardiovascular and cerebrovascular diseases in human is controversial, and there is little information about how exposures to ambient air pollution contribution to the mortality of cardiovascular and cerebrovascular diseases among Chinese. The aim of the present study was to examine whether exposure to ambient-air pollution increases the risk for cardiovascular and cerebrovascular disease.. We conducted a retrospective cohort study among humans to examine the association between compound-air pollutants [particulate matter <10 µm in aerodynamic diameter (PM(10)), sulfur dioxide (SO(2)) and nitrogen dioxide (NO(2))] and mortality in Shenyang, China, using 12 years of data (1998-2009). Also, stratified analysis by sex, age, education, and income was conducted for cardiovascular and cerebrovascular mortality. The results showed that an increase of 10 µg/m(3) in a year average concentration of PM(10) corresponds to 55% increase in the risk of a death cardiovascular disease (hazard ratio [HR], 1.55; 95% confidence interval [CI], 1.51 to 1.60) and 49% increase in cerebrovascular disease (HR, 1.49; 95% CI, 1.45 to 1.53), respectively. The corresponding figures of adjusted HR (95%CI) for a 10 µg/m(3) increase in NO(2) was 2.46 (2.31 to 2.63) for cardiovascular mortality and 2.44 (2.27 to 2.62) for cerebrovascular mortality, respectively. The effects of air pollution were more evident in female that in male, and nonsmokers and residents with BMI<18.5 were more vulnerable to outdoor air pollution.. Long-term exposure to ambient air pollution is associated with the death of cardiovascular and cerebrovascular diseases among Chinese populations.

Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Cardiovascular Diseases; Cerebrovascular Disorders; China; Educational Status; Environmental Exposure; Female; Humans; Male; Middle Aged; Nitrogen Dioxide; Particulate Matter; Public Policy; Retrospective Studies; Risk Assessment; Sex Distribution; Social Class; Sulfur Dioxide; Time Factors

Relatively little research exists focusing on the impact of air pollution on hospital admissions in Asia compared to the extensive work conducted in the USA and Europe. The issue is of particular importance because of the frequency, intensity and health effects of Asian sandstorms. This work investigates the relation between cause-specific hospital admissions and sandstorms and air pollution in Taipei, Taiwan's capital.. Time-series analyses of asthma, pneumonia, ischaemic heart disease and cerebrovascular disease hospital admissions were performed for Taipei. An eight-year time period (1995-2002) was considered for various indicators of sandstorms and the pollutants NO(2), CO, ozone, SO(2), PM(10), and PM(2.5). Pollution effects based on single-day lags of 0, 1, 2 and 3 days were explored, along with the average of the same day and previous three days (L03).. The risk of ischaemic heart disease admissions was associated with several sandstorm metrics, including indicators of high PM(10) levels in the Taipei area, indicators of high PM(10) at a monitor designed to measure background pollution, the PM coarse fraction, and the ratio of PM(10) to PM(2.5). However, the lag structure of effect was not consistent across sandstorm indicators. Hospital admissions for this disease were 16-21% higher on sandstorm days compared to other days. This cause was also associated with transportation-related pollutants, NO(2), CO and PM(2.5). Asthma admissions rose 4.48% (95% CI 0.71% to 8.38%) per 28 mug/m(3) increase in L03 PM(10) levels and 7.60% (95% CI 2.87% to 12.54%) per 10 ppb increase in L03 ozone. Cerebrovascular disease admissions were associated with PM(10) and CO, both at lag 3 days. SO(2) exhibited no relation with admissions.. Risk of hospital admissions in Taipei may be increased by air pollution and sandstorms. Additional research is needed to clarify the lag structure and magnitude of such effects.

Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Cerebrovascular Disorders; Environmental Exposure; Environmental Monitoring; Fourier Analysis; Hospitalization; Humans; Myocardial Ischemia; Nitrogen Dioxide; Ozone; Particle Size; Particulate Matter; Pneumonia; Silicon Dioxide; Sulfur Dioxide; Taiwan; Urban Health; Weather

This article describes a Poisson regression model for time trends of mortality to detect the long-term effects of common levels of air pollution on lung cancer, in which the adjustment for cigarette smoking is not always necessary. The main hypothesis to be tested in the model is that if the long-term and common-level air pollution had an effect on lung cancer, the death rate from lung cancer could be expected to increase gradually at a higher rate in the region with relatively high levels of air pollution than in the region with low levels, and that this trend would not be expected for other control diseases in which cigarette smoking is a risk factor. Using this approach, we analyzed the trend of mortality in females aged 40 to 79, from lung cancer and two control diseases, ischemic heart disease and cerebrovascular disease, based on vital statistics in 23 wards of the Tokyo metropolitan area for 1972 to 1988. Ward-specific mean levels per day of SO2 and NO2 from 1974 through 1976 estimated by Makino (1978) were used as the ward-specific exposure measure of air pollution. No data on tobacco consumption in each ward is available. Our analysis supported the existence of long-term effects of air pollution on lung cancer.

Topics: Adult; Aged; Air Pollutants; Air Pollution; Cerebrovascular Disorders; Cohort Studies; Environmental Exposure; Female; Humans; Lung Neoplasms; Middle Aged; Myocardial Ischemia; Nitrogen Dioxide; Poisson Distribution; Regression Analysis; Risk Factors; Smoking; Sulfur Dioxide; Tokyo; Vital Statistics