Page last updated: 2024-09-03

nitroflurbiprofen and Bone Loss, Osteoclastic

nitroflurbiprofen has been researched along with Bone Loss, Osteoclastic in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Idris, AI; Ralston, SH; van't Hof, RJ1
Del Soldato, P; Idris, AI; Ralston, SH; van't Hof, RJ1
Armour, KE; Armour, KJ; Del Soldato, P; Ralston, SH; Torbergsen, AC; van 't Hof, RJ1

Other Studies

3 other study(ies) available for nitroflurbiprofen and Bone Loss, Osteoclastic

ArticleYear
The nitrosylated flurbiprofen derivative HCT1026 inhibits cytokine-induced signalling through a novel mechanism of action.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Actins; Animals; Apoptosis; Bone Resorption; Cytokines; Enzyme Activation; Flurbiprofen; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitroso Compounds; Osteoclasts; RANK Ligand; Signal Transduction

2009
The flurbiprofen derivatives HCT1026 and HCT1027 inhibit bone resorption by a mechanism independent of COX inhibition and nitric oxide production.
    Bone, 2004, Volume: 35, Issue:3

    Topics: Animals; Bone Resorption; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Mice; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Rabbits

2004
Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026).
    Arthritis and rheumatism, 2001, Volume: 44, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Flurbiprofen; In Vitro Techniques; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Ovariectomy; Spleen

2001